2D Structure
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2D chemical structural formula diagram.
3D Structure
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This 3D model represents a theoretically simulated conformation and is for reference only.
Check the
ARN-509 (Apalutamide)
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | 4-[7-[6-cyano-5-(trifluoromethyl)-3-pyridinyl]-8-oxo-6-sulfanylidene-5,7-diazaspiro[3.4]octan-5-yl]-2-fluoro-N-methylbenzamide | |
|---|---|---|
| CAS Number | 956104-40-8 | |
| Molecular Formula |
C21H15F4N5O2S |
|
| Molecular Weight (MW) | 477.43 | |
| SMILES | CNC(=O)C1=C(C=C(C=C1)N2C(=S)N(C(=O)C23CCC3)C4=CC(=C(N=C4)C#N)C(F)(F)F)F | |
| InChIKey | HJBWBFZLDZWPHF-UHFFFAOYSA-N |
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
95 mg/mL
(198.98 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 7 mg/mL |
| Water | Insoluble |
| DMSO |
18 mg/mL
(37.7 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 5 mg/mL |
| Water | Insoluble |
| DMSO |
95 mg/mL
(198.98 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 28 mg/mL |
| Water | Insoluble |
| DMSO |
95 mg/mL
(198.98 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 8 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
- ARN-509 (Apalutamide) Mechanism of Action: Androgen Receptor Inhibition in Prostate Cancer Cell Research
- ARN-509 (Apalutamide) Clinical Trials
- ARN-509 (Apalutamide): Selectivity & Specificity
- ARN-509 (Apalutamide) Working Concentration | Cell Culture | Treatment
- ARN-509 (Apalutamide) Solubility in DMSO
- ARN-509 (Apalutamide) Stock Solution
- ARN-509 (Apalutamide) Storage
- ARN-509 (Apalutamide) Stability
- ARN-509 (Apalutamide) Combination Database
- ARN-509 (Apalutamide) Molecular Weight
- ARN-509 (Apalutamide) SMILES
- ARN-509 (Apalutamide) CAS Number
- ARN-509 (Apalutamide) IC50 for Cell-based and Cell-free Assays
- ARN-509 (Apalutamide) Sigma (AMBH2D6FA54D)? Try a better option.
- ARN-509 (Apalutamide) MedChemExpress (HY-16060)? Try a better option.
- ARN-509 (Apalutamide) APExBIO (A8364)? Try a better option.
- ARN-509 (Apalutamide) SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.