Home Biosimilar Antibodies Protein Tyrosine Kinase Trk receptor Anti-TrkB / NTRK2
For research use only. Not for use in humans.

Anti-TrkB / NTRK2

Synonyms: BDNF/NT-3 growth factors receptor

Anti-TrkB / NTRK2 is an antibody targeting TrkB. It is used to improve nerve function, including treatment of peripheral neuropathies. MW :146.68 KD.

Anti-TrkB / NTRK2

Quality Control

Batch: A310301 Purity: 99% Protein concentration: 6.716mg/ml Endotoxin Level: ＜1EU/mg
99

Specificity

Name Citation TrkA TrkB TrkC Trk receptor Others
SP600125 1063 serine/threonine kinase,JNK2,JNK1
Danusertib (PHA-739358) 46 Aurora A,Abl,RET
BMS-754807 54 Insulin Receptor,IGF-1R,Met
GW441756 20
UNC2025 7 FLT3,Mer,Axl
Taletrectinib (DS-6051b) 5 ROS1
Altiratinib 3 MET Y1230C,MET D1228N,MET Y1230H
Selitrectinib (LOXO-195) 4 TRKA G595R,TRKC G623R,TRKC G696A
CH7057288 0
BMS-935177 4 BTK,TEC,BLK
PF-06273340 0
Sitravatinib (MGCD516) 7 DDR2,EPHA3,Axl
ANA-12 44
GNF-5837 7
Belizatinib (TSR-011) 0 ALK
Repotrectinib (TPX-0005) 12 ROS1,WT ALK,ALK(L1196M)
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1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.

Mechanism of Action

Description
Anti-TrkB / NTRK2 is an antibody targeting TrkB. It is used to improve nerve function, including treatment of peripheral neuropathies. MW :146.68 KD.
References

Product Details

Isotype Human IgG2SA
Source CHO
Formulation 100 mM Pro-Ac, 20mM Arg, pH5.0
Storage
(From the date of receipt)		 Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

Tech Support

Handling Instructions

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