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For research use only. Not for use in humans.
Anti-TGFb1 (NIS793)
Synonyms: NIS793
Anti-TGFb1 (NIS793) is a monoclonal antibody targeting TGF-β. It can be used in metastatic melanoma and non-small cell-lung cancer. MW :143.78 KD
Quality Control
Specificity
| Name | Citation | ALK1 | ALK2 | ALK3 | ALK4 | TGFβRI/ALK5 | ALK6 | TGFβRII | TGF-β | Smad3 | ALK7 | Others |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SB431542 | 799 | |||||||||||
| LDN-193189 | 262 | |||||||||||
| Galunisertib (LY2157299) | 192 | |||||||||||
| LY2109761 | 137 | |||||||||||
| SB-525334 | 116 | |||||||||||
| SB505124 | 37 | |||||||||||
| GW788388 | 25 | |||||||||||
| LY364947 | 49 | RIPK2,CK1δ,MLK-7K | ||||||||||
| RepSox (E-616452) | 82 | |||||||||||
| LDN-193189 Dihydrochloride | 103 | |||||||||||
| K02288 | 24 | |||||||||||
| TGFβRI-IN-3 | 2 | |||||||||||
| R-268712 | 1 | |||||||||||
| BIBF-0775 | 0 | |||||||||||
| TP0427736 HCl | 6 | |||||||||||
| A-83-01 | 68 | |||||||||||
| LDN-214117 | 4 | |||||||||||
| SD-208 | 21 | |||||||||||
| Vactosertib (TEW-7197) | 28 | |||||||||||
| ML347 | 5 | |||||||||||
| LDN-212854 | 7 | |||||||||||
| DMH1 | 61 | |||||||||||
| Dorsomorphin Dihydrochloride | 512 | AMPK | ||||||||||
| PF-06952229 | 0 | |||||||||||
| Ginsenoside Rh4 | 0 | |||||||||||
| SIS3 | 16 | |||||||||||
| AUDA | 0 | TNF-α,IL-1β,MMP-9 | ||||||||||
| PD 169316 | 2 | Activin A,Enterovirus71,p38 MAPK | ||||||||||
| TA-02 | 0 | p38 MAPK | ||||||||||
| ITD-1 | 14 | |||||||||||
| LY 3200882 | 5 | |||||||||||
| Alantolactone | 3 | STAT3 | ||||||||||
| Halofuginone | 12 | prolyl-tRNA synthetase | ||||||||||
| SIS3 Hydrochloride | 85 | |||||||||||
| Dorsomorphin | 474 | AMPK | ||||||||||
| Hesperetin | 4 | Histamine receptor |
Expand to Check More
1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.
Mechanism of Action
| Description |
Anti-TGFb1 (NIS793) is a monoclonal antibody targeting TGF-β. It can be used in metastatic melanoma and non-small cell-lung cancer. MW :143.78 KD
|
References |
|---|
Product Details
| Isotype | Human IgG1 |
|---|---|
| Source | CHO |
| Formulation | 100 mM Pro-Ac, 20mM Arg, pH5.0 |
| Storage (From the date of receipt) |
Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles. |
Comparison of Clones for
*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)
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Products are for research use only. Not for human use. We do not sell to patients.
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