For research use only. Not for use in humans.

Anti-MSPR / RON / CD136 (H5B14)

Synonyms: H5B14 Cat.No.A3166

Anti-MSPR / RON / CD136 (H5B14) is a neutralizing human monoclonal antibody-drug conjugate that targets RON binding to its ligand, macrophage-stimulating protein (MSP). It has an strong potential in treatment of chronic liver inflammation and also in autoimmune diseases. MW :156.7 KD.

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Datasheet

Specificity

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1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.

Mechanism of Action

Description	Anti-MSPR / RON / CD136 (H5B14) is a neutralizing human monoclonal antibody-drug conjugate that targets RON binding to its ligand, macrophage-stimulating protein (MSP). It has an strong potential in treatment of chronic liver inflammation and also in autoimmune diseases. MW :156.7 KD.
References	[1] https://pubmed.ncbi.nlm.nih.gov/31519211/

Cell Lines	Assay Type	Concentration	Incubation Time	Formulation	Activity Description	PMID

Product Details

Isotype	Human IgG1
Source	CHO
Formulation	100 mM Pro-Ac, 20mM Arg, pH5.0
Storage (From the date of receipt)	Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

^*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

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