For research use only. Not for use in humans.

Anti-IL-3Ra / CD123 (SGN-CD123A)

Synonyms: CD123A Cat.No.A2631 Purity:99%

Anti-IL-3Ra / CD123 (SGN-CD123A) is an antibody-drug conjugate targeting IL-3 alpha chain receptor (CD123). It is a potent antileukemic agent in treatment of acute myelogenous leukemia(AML). MW :146.14 KD.

Anti-IL-3Ra / CD123 (SGN-CD123A)

Quality Control

Batch: Purity: 99% Protein concentration: 7.366mg/ml Endotoxin Level: ＜1EU/mg

99

Specificity

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1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.

Mechanism of Action

Description	Anti-IL-3Ra / CD123 (SGN-CD123A) is an antibody-drug conjugate targeting IL-3 alpha chain receptor (CD123). It is a potent antileukemic agent in treatment of acute myelogenous leukemia(AML). MW :146.14 KD.
References	[1] https://pubmed.ncbi.nlm.nih.gov/29142066/

Cell Lines	Assay Type	Concentration	Incubation Time	Formulation	Activity Description	PMID

Product Details

Molecular Weight	146.14
Isotype	Human IgG1
Source	CHO
Purification	AKTA
Sterility	0.2 μM filtered
Formulation	100 mM Pro-Ac, 20mM Arg, pH5.0
Storage (From the date of receipt)	Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

^*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

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