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For research use only. Not for use in humans.

Anti-c-RET

Anti-c-RET is a monoclonal antibody against the receptor tyrosine kinase Ret (c-Ret) expressed in cells of neuroblastoma and substantia nigra, a responsive locus of Parkinson's disease. MW: 146.74 KD.

Anti-c-RET

Quality Control

  • Cited in Nature Medicine for its top-tier quality
  • SDS
  • Datasheet

Specificity

Name Citation c-RET Others
Danusertib (PHA-739358) 46 Aurora A,Abl,TrkA
TG101209 20 JAK2,FLT3,JAK3
Agerafenib (CEP-32496) 6 PDGFRβ,LCK,c-Kit
CS-2660 (JNJ-38158471) 0 VEGFR2,Kit
WHI-P180 0 KDR
GSK3179106 1
Apatinib (YN968D1) 28 VEGFR2
AD80 7 S6 Kinase,Src,Raf
BAW2881 (NVP-BAW2881) 3 hVEGFR2,C-Raf-1,B-RAFV599E
ON123300 4 CDK4/CyclinD1,ARK5,CDK6/CyclinD1
Amuvatinib (MP-470) 21 RAD51,c-Met,c-Kit (D816H)
TPX-0046 0
AST-487 (NVP-AST487) 3 c-Abl,c-Kit,KDR
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1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.

Mechanism of Action

Description
Anti-c-RET is a monoclonal antibody against the receptor tyrosine kinase Ret (c-Ret) expressed in cells of neuroblastoma and substantia nigra, a responsive locus of Parkinson's disease. MW: 146.74 KD.

Product Details

Molecular Weight 146.74
Isotype Human IgG1
Source CHO
Purification AKTA
Sterility 0.2 μM filtered
Formulation 100 mM Pro-Ac, 20mM Arg, pH5.0
Storage
(From the date of receipt)		 Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

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