Home Biosimilar Antibodies Proteases BACE Anti-BACE1 (Genentech anti-BACE1)
For research use only. Not for use in humans.

Anti-BACE1 (Genentech anti-BACE1)

Synonyms: null

Anti-BACE1 (Genentech anti-BACE1) is a monoclonal anti-BACE1 antibody (mAb) that reduces endogenous BACE1 activity and amyloid-β (Aβ) production. It has the potential to treat Alzheimer's disease. MW: 144.22 KD.

Anti-BACE1 (Genentech anti-BACE1)

Quality Control

  • Cited in Nature Medicine for its top-tier quality
  • SDS
  • Datasheet

Specificity

Name Citation BACE Others
LY2886721 19
LY2811376 19 Aβ
Loganin 0 AChE,BChE
Verubecestat (MK-8931) 8
Lanabecestat (AZD3293) 6
Verubecestat (MK-8931) Trifluoroacetate 10
AZD3839 7
Nodakenetin 0 Bcl-2,Bax,BChE
Expand to Check More
1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.

Mechanism of Action

Description
Anti-BACE1 (Genentech anti-BACE1) is a monoclonal anti-BACE1 antibody (mAb) that reduces endogenous BACE1 activity and amyloid-β (Aβ) production. It has the potential to treat Alzheimer's disease. MW: 144.22 KD.
References

Product Details

Molecular Weight 144.22
Isotype Human IgG1
Source CHO
Purification AKTA
Sterility 0.2 μM filtered
Formulation 100 mM Pro-Ac, 20mM Arg, pH5.0
Storage
(From the date of receipt)		 Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

Tech Support

Handling Instructions

Tel: +1-832-582-8158 Ext:3

If you have any other enquiries, please leave a message.