Home Biosimilar Antibodies Stem Cells & Wnt ALK Anti-ACVR1 / ALK-2 (DS-6016a)
For research use only. Not for use in humans.

Anti-ACVR1 / ALK-2 (DS-6016a)

Synonyms: Prafnosbart

Anti-ACVR1 / ALK-2 (DS-6016a) monoclonal antibody targeting ALK-2. It can be used in the treatment of fibrodysplasia ossificans progressiva (FOP). MW :145.56.

Anti-ACVR1 / ALK-2 (DS-6016a)

Quality Control

  • Cited in Nature Medicine for its top-tier quality
  • SDS
  • Datasheet

Specificity

Name Citation ALK Others
TAE684 (NVP-TAE684) 83
AP26113-analog (ALK-IN-1) 4 EGFR(C797S/del19),IGF1R,EGFR(del19)
GSK1838705A 18 Insulin Receptor,IGF-1R
AZD3463 7 IGF-1R
ASP3026 4
NVL-655 (Neladalkib) 1 ROS1,TrkB,FAK
Envonalkib 0
TL13-112 0
ZX-29 0
MS4078 0
Ensartinib dihydrochloride 7 TPM3-TRKA,GOPC-ROS1,TRKC
Belizatinib (TSR-011) 0 TrkC,TrkB,TrkA
Repotrectinib (TPX-0005) 12 Trk receptor,ROS1,Src
APG-2449 0
Iruplinalkib 0 ROS1
Conteltinib(CT-707) 0 Pyk2,FAK
Itacnosertib (TP-0184) 0
Zilurgisertib fumarate 0
ALK inhibitor 1 0 FAK,TSSK2
X-376 0
HG-14-10-04 0
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1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.

Mechanism of Action

Description
Anti-ACVR1 / ALK-2 (DS-6016a) monoclonal antibody targeting ALK-2. It can be used in the treatment of fibrodysplasia ossificans progressiva (FOP). MW :145.56.
References

Product Details

CAS No. 2566473-71-8
Molecular Weight 145.56
Isotype Human IgG1
Source CHO
Purification AKTA
Sterility 0.2 μM filtered
Formulation 100 mM Pro-Ac, 20mM Arg, pH5.0
Storage
(From the date of receipt)		 Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

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