Clinical Trials

Anlotinib is currently being evaluated in numerous clinical trials spanning Phase 1 safety evaluations to Phase 4 post-marketing research across oncology indications, including non-small cell lung cancer, soft tissue sarcoma, esophageal squamous cell carcinoma, breast cancer, and pheochromocytoma or paraganglioma. Conducted by diverse organizations, including academic medical centers and pharmaceutical sponsors, these studies evaluate both monotherapies and combination regimens. The trial landscape represents the full spectrum of recruitment statuses, encompassing studies that are not yet recruiting, actively recruiting, active but not recruiting, and completed.

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT07540390 NOT_YET_RECRUITING
Nasopharyngeal Carcinoma
Sun Yat-sen University
2026-05-08 PHASE3
NCT07612098 NOT_YET_RECRUITING
Soft Tissue Sarcoma (STS)
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
2026-07-01 PHASE2
NCT06992336 RECRUITING
Breast Cancer
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
2025-04-10 PHASE2
NCT07156643 NOT_YET_RECRUITING
Locally Advanced Soft Tissue Sarcoma
The First Affiliated Hospital with Nanjing Medical University
2025-10-01 PHASE2
NCT07520760 RECRUITING
HER 2 Negative Breast Cancer
Sun Yat-sen University
2026-04-01 PHASE2
NCT07193186 NOT_YET_RECRUITING
Thyroid Cancer
Fudan University
2026-04-01 PHASE2
NCT06662877 NOT_YET_RECRUITING
Biliary Tract Cancer; Second Line Treatment; Chemotherapy; Tyrosine Kinase Inhibitor
Sun Yat-sen University
2024-11-25 PHASE2; PHASE3
NCT07562581 RECRUITING
Non-small Cell Lung Caner; KRAS-mutated; Metastasis; Previous Treamted
Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd.
2026-06-15 PHASE2
NCT07643350 NOT_YET_RECRUITING
NSCLC
The Third Xiangya Hospital of Central South University
2026-05-15 PHASE2
NCT07470840 NOT_YET_RECRUITING
Locally Advanced or Metastatic Renal Cell Carcinoma
Fujian Cancer Hospital
2027-02-01 PHASE2
NCT07355855 NOT_YET_RECRUITING
Rhabdomyosarcoma
Fudan University
2026-01 PHASE2
NCT07627464 NOT_YET_RECRUITING
Renal Cell Carcinoma (RCC)
Tianjin Medical University Cancer Institute and Hospital
2026-05-31 PHASE2
NCT07239622 NOT_YET_RECRUITING
Ovarian Cancer; Ovarian Clear Cell Carcinoma
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
2026-01-01 PHASE2
NCT07646080 NOT_YET_RECRUITING
Dermatofibrosarcoma Protuberans (DFSP)
Yanjie Zhang, MD
2026-06-15 PHASE2
NCT07075250 NOT_YET_RECRUITING
Platinum-resistant Ovarian Cancer (PROC)
Peking University People's Hospital
2025-09-01 PHASE4
NCT07671560 NOT_YET_RECRUITING
ALK-positive, Locally Advanced or Metastatic (TNM Stage IIIB-IV) Non-small Cell Lung Cancer That Has Developed Resistance to Prior Treatment With Lorlatinib
Qiming Wang
2026-07-01 PHASE4
NCT07636226 NOT_YET_RECRUITING
Small Cell Lung Cancer
Sun Yat-sen University
2026-07-30 PHASE2; PHASE3
NCT07128693 NOT_YET_RECRUITING
Esophageal Squamous Cell Carcinoma
The First Affiliated Hospital of Zhengzhou University
2025-09 PHASE2
NCT07446335 NOT_YET_RECRUITING
Advanced Esophageal Squamous Cell Carcinoma
The First Affiliated Hospital of Zhengzhou University
2026-04 PHASE3
NCT07137884 NOT_YET_RECRUITING
Rhabdomyosarcoma Recurrent; Maintenance Treatment
Sun Yat-sen University
2025-10-01 PHASE2
NCT07294261 NOT_YET_RECRUITING
Local Advanced or Metastatic NSCLC
Sun Yat-sen University
2025-12-23 PHASE2
NCT07780578 NOT_YET_RECRUITING
Non-Small Cell Lung Cancer (NSCLC, Locally Advanced or Metastatic, Second-line
Fudan University
2026-09-30 PHASE2
NCT06356675 NOT_YET_RECRUITING
Advanced NSCLC
The First Affiliated Hospital, Guangzhou University of Traditional Chinese Medicine
2024-07-01 PHASE4
NCT07396454 RECRUITING
HER2-Negative Breast Cancer
The First Affiliated Hospital with Nanjing Medical University
2026-02-10 PHASE2
NCT07616141 NOT_YET_RECRUITING
Adenoid Cystic Carcinoma
Eye & ENT Hospital of Fudan University
2026-06-01 PHASE2
NCT07632209 NOT_YET_RECRUITING
SCLC, Extensive Stage
Yayi He
2026-06 PHASE2
NCT07165951 RECRUITING
Metastatic Pancreatic Ductal Adenocarcinoma
Shanghai Chia Tai Tianqing Pharmaceutical Technology Development Co., Ltd.
2025-12-02 PHASE3
NCT07455019 RECRUITING
Esophageal Cancer
The First Affiliated Hospital with Nanjing Medical University
2025-05-01 PHASE2
NCT04322617 RECRUITING
Non-small Cell Lung Cancer
Hunan Province Tumor Hospital
2020-03-24 PHASE2; PHASE3
NCT07363512 NOT_YET_RECRUITING
HCC - Hepatocellular Carcinoma
Henan Cancer Hospital
2026-01-05 PHASE2
NCT07545213 NOT_YET_RECRUITING
Non-small Cell Lung Cancer; EGFR Mutant Advanced Non-small Cell Lung Cancer
The Fourth Affiliated Hospital of Zhejiang University School of Medicine
2026-04-20 PHASE2
NCT07537777 NOT_YET_RECRUITING
Hepatocellular Carcinoma (HCC); First-line Targeted Therapy Failure; Oligometastatic Hepatocellular Carcinoma; Benmelstobart; Anlotinib; SBRT
Nanfang Hospital, Southern Medical University
2026-04-20 PHASE2
NCT07385079 NOT_YET_RECRUITING
Nasopharyngeal Cancinoma (NPC); Nasopharyngeal Cancer
Sun Yat-sen University
2026-03-01 PHASE3
NCT06848439 NOT_YET_RECRUITING
Mouth Neoplasms; Neoadjuvant Therapy; Immunotherapy; Molecular Targeted Therapy
Jiangsu Cancer Institute & Hospital
2025-06-15 PHASE2
NCT07602101 NOT_YET_RECRUITING
Clear Cell Renal Cell Carcinoma
RenJi Hospital
2026-05-31 PHASE2
NCT06681285 NOT_YET_RECRUITING
Esophageal Carcinoma
Hebei Medical University Fourth Hospital
2024-11-01 PHASE2
NCT07010393 NOT_YET_RECRUITING
Thyroid Neoplasms
Fujian Medical University
2025-07-01 PHASE4
NCT04165330 ACTIVE_NOT_RECRUITING
Solid Tumor, Adult; Soft Tissue Sarcoma; Non Small Cell Lung Cancer; Small Cell Lung Cancer
Sarcoma Oncology Research Center, LLC
2019-10-17 PHASE1; PHASE2
NCT07398326 RECRUITING
Colorectal Cancer
Shanghai Changzheng Hospital
2026-02-24 PHASE2
NCT07205185 NOT_YET_RECRUITING
Soft Tissue Sarcoma (STS)
Fudan University
2025-10-01 PHASE2
NCT05167994 RECRUITING
Sarcoma,Soft Tissue; Extremity; Trunk; Anlotinib; Intensity-modulated Radiotherapy; Major Wound Complications
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
2020-05-01 PHASE2
NCT05582499 RECRUITING
Breast Neoplasm; Breast Cancer; Breast Tumors; Triple-Negative Breast Cancer (TNBC); HER2-positive Breast Cancer; HER2-negative Breast Cancer; Hormone Receptor Positive Tumor; Hormone Receptor Negative Tumor; Early-stage Breast Cancer; Locally Advanced Breast Cancer
Fudan University
2022-11-01 PHASE2
NCT07581821 RECRUITING
Recurrent or Metastatic Nasopharyngeal Carcinoma
Ming-Yuan Chen
2025-09-15 PHASE2
NCT07728955 NOT_YET_RECRUITING
Small Cell Lung Cancer ( SCLC )
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
2026-08-01 PHASE3
NCT07627347 RECRUITING
ESCC
Nanfang Hospital, Southern Medical University
2026-05-18
NCT06141226 RECRUITING
Non-small-cell Lung Cancer
Tianjin Medical University Cancer Institute and Hospital
2023-04-12 PHASE2
NCT07745257 NOT_YET_RECRUITING
HR-positive, HER2-negative Metastatic Breast Cancer With Brain Metastases
Sun Yat-sen University
2026-08-28 PHASE2
NCT07444918 NOT_YET_RECRUITING
Relapsed or Refractory Pediatric Malignant Solid Tumors (Including Neuroblastoma, Rhabdomyosarcoma, Ewing Sarcoma, Osteosarcoma)
Tianjin Medical University Cancer Institute and Hospital
2026-03-01 PHASE2
NCT07307443 NOT_YET_RECRUITING
SMARCA4-Deficient Tumor; Locally Advanced or Metastatic Lung Cancer
Zhijie Wang
2026-02-01 PHASE2
NCT06475599 NOT_YET_RECRUITING
Endometrial Cancer
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2024-07 PHASE3
NCT06662006 RECRUITING
Advanced Metastatic Pancreatic Cancer
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
2024-03-01 PHASE2
NCT07172412 NOT_YET_RECRUITING
Extensive Stage Lung Small Cell Cancer
Tianjin Medical University Cancer Institute and Hospital
2025-11 PHASE2
NCT03016819 RECRUITING
Alveolar Soft Part Sarcoma; Leiomyosarcoma; Synovial Sarcoma; Soft-Tissue Sarcoma
Advenchen Laboratories, LLC
2017-08-15 PHASE3
NCT07231575 NOT_YET_RECRUITING
Neoadjuvant Immunotherapy; NSCLC; Chemo-free Therapy
Sun Yat-sen University
2025-11-10 PHASE2
NCT07330544 RECRUITING
Breast Cancer
Zhejiang Cancer Hospital
2025-11-24 PHASE2
NCT06978153 NOT_YET_RECRUITING
Limited Stage Small Cell Lung Cancer
Tang-Du Hospital
2025-05-20 PHASE2
NCT07548177 RECRUITING
Alveolar Soft Part Sarcoma
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2026-04-02 PHASE2
NCT07538258 NOT_YET_RECRUITING
Limited-stage Small Cell Lung Cancer (LS-SCLC)
Yayi He
2026-04-20 PHASE2
NCT07703228 ACTIVE_NOT_RECRUITING
NSCLC (Advanced Non-small Cell Lung Cancer); NSCLC Stage IIIB~IV; Second-line Therapy; Metastases
Nanfang Hospital, Southern Medical University
2025-08-13 PHASE2
NCT07359053 RECRUITING
Sarcoma
Shanghai 6th People's Hospital
2025-12-25 PHASE2
NCT07538271 NOT_YET_RECRUITING
SCLC, Extensive Stage
Yayi He
2026-04-20 PHASE2
NCT07286240 RECRUITING
Treatment of Recurrent Ovarian Cancer
Affiliated Cancer Hospital & Institute of Guangzhou Medical University
2025-11-15 PHASE2
NCT07601178 RECRUITING
TNBC, Triple Negative Breast Cancer
Jiangsu Cancer Institute & Hospital
2026-04-17 PHASE2
NCT06945705 RECRUITING
NSCLC
Henan Cancer Hospital
2025-04-02 PHASE2
NCT07142421 ACTIVE_NOT_RECRUITING
Esophageal Squamous Cell Carcinoma (ESCC)
First Affiliated Hospital of Zhejiang University
2025-08-06 PHASE2
NCT07443397 RECRUITING
Whole-Brain Radiotherapy
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
2025-08-29 PHASE3
NCT07501169 NOT_YET_RECRUITING
Extensive-stage Small Cell Lung Cancer (ES-SCLC)
Sichuan University
2026-04-01 PHASE2
NCT07089199 RECRUITING
NSCLC; Tislelizumab; Anlotinib; Nab-paclitaxel
Qilu Hospital of Shandong University
2025-07-25 PHASE2
NCT06506838 RECRUITING
Soft Tissue Sarcoma; Doxorubicin; Radiotherapy
Guangdong Provincial People's Hospital
2024-08-10 PHASE4
NCT07635290 ACTIVE_NOT_RECRUITING
Previously Treated, Advanced; Biliary Tract Cancers
West China Hospital
2026-06-03 PHASE2
NCT06977828 NOT_YET_RECRUITING
NSCLC (Non-small Cell Lung Cancer); Neoadjuvant Immunotherapy; Adjuvant Immunotherapy
The First Affiliated Hospital with Nanjing Medical University
2025-07-20 PHASE2
NCT05830500 RECRUITING
Medullary Thyroid Cancer
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2023-06-19 PHASE4
NCT06851247 RECRUITING
Nasopharyngeal Carcinoma
Sun Yat-sen University
2025-01-03 PHASE2
NCT06429397 NOT_YET_RECRUITING
Pheochromocytoma
Sun Yat-sen University
2025-05-01 PHASE2
NCT07022301 NOT_YET_RECRUITING
Small Cell Lung Cancer Extensive Stage; Resistance to Immunotherapy
First Affiliated Hospital of Wannan Medical College
2025-07 PHASE2
NCT06931145 NOT_YET_RECRUITING
Extensive-stage Small Cell Lung Cancer
Peking Union Medical College Hospital
2025-04-15 PHASE4
NCT07139470 NOT_YET_RECRUITING
Triple Negative Breast Cancer
Tianjin Medical University Cancer Institute and Hospital
2025-08-15 PHASE1; PHASE2
NCT06761417 RECRUITING
Solid Tumors; Children; Adolescents
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
2025-01-24 PHASE2
NCT06874933 RECRUITING
HR+/HER2- Breast Cancer
First Affiliated Hospital of Zhejiang University
2025-05-04 PHASE2
NCT07438886 NOT_YET_RECRUITING
Healthy Volunteer
Advenchen Laboratories Nanjing Ltd.
2026-03-02 PHASE1
NCT07320963 NOT_YET_RECRUITING
Nasopharyngeal Carcinoma
Sun Yat-sen University
2026-03-31 PHASE1; PHASE2
NCT06761027 RECRUITING
Locally Advanced Pancreatic Cancer; Metastatic Pancreatic Cancer
Fujian Provincial Hospital
2024-12-23 PHASE1; PHASE2
NCT07388875 NOT_YET_RECRUITING
Extensive-Stage Small Cell Lung Cancer
China Medical University, China
2026-02-24 PHASE2
NCT06851169 NOT_YET_RECRUITING
Non Small Cell Lung Cancer
Tang-Du Hospital
2025-04-01 PHASE2
NCT07489300 NOT_YET_RECRUITING
Ovarian Cancer; Fallopian Tube Cancers; Primary Peritoneal Cancer
Second Affiliated Hospital, Zhejiang University, School of Medicine
2026-03-30 PHASE2
NCT07358520 NOT_YET_RECRUITING
Proteinuria
Fudan University
2026-01-28 PHASE4
NCT07358676 RECRUITING
Small Cell Lung Cancer (SCLC); SCLC, Extensive Stage
Tianjin Medical University Cancer Institute and Hospital
2026-02-01 PHASE2
NCT07510594 NOT_YET_RECRUITING
Large-Cell Neuroendocrine Carcinoma of the Lung; Extrapulmonary Neuroendocrine Carcinoma
Tianjin Medical University Cancer Institute and Hospital
2026-05-01 PHASE2
NCT06476093 RECRUITING
Non-Small-Cell Lung Cancer; Brain Metastases
The First People's Hospital of Lianyungang
2024-07-01
NCT06739395 RECRUITING
Solid Tumor; Precision Medicine
Tianjin Medical University Second Hospital
2024-11-01 PHASE2
NCT04959500 ACTIVE_NOT_RECRUITING
Glioblastoma
Sun Yat-sen University
2021-07-21 PHASE2
NCT06331169 RECRUITING
Breast Cancer
Fudan University
2024-07-31 PHASE1
NCT07025174 RECRUITING
Bile Duct Carcinoma; Gall Bladder Cancer; Biliary Tract Cancer; Cholangiocarcinoma
First Affiliated Hospital of Zhejiang University
2025-06-01 PHASE2
NCT04136535 RECRUITING
NSCLC Stage IV
Fudan University
2021-11-18 PHASE2
NCT06195228 RECRUITING
Advanced Thyroid Cancer Patients Who Received Target Therapy
Fudan University
2020-01-01 PHASE4
NCT06699576 NOT_YET_RECRUITING
Osteosarcoma; Soft Tissue Sarcoma (STS)
Hansoh BioMedical R&D Company
2024-12-20 PHASE1
NCT05926700 RECRUITING
Soft Tissue Sarcoma
Second Affiliated Hospital, Zhejiang University, School of Medicine
2024-02-28 PHASE2
NCT06838910 RECRUITING
Thymic Carcinoma; Thymoma
The First Affiliated Hospital with Nanjing Medical University
2025-03-31 PHASE2
NCT04344158 ACTIVE_NOT_RECRUITING
Advanced Hepatocellular Carcinoma (HCC)
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2020-08-11 PHASE3
NCT06767813 RECRUITING
Pancreatic Neoplasms
Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd.
2024-03-19 PHASE2
NCT05252078 RECRUITING
Esophageal Squamous Cell Carcinoma; Esophageal Neoplasms; Esophageal Diseases; Gastrointestinal Neoplasms; Gastrointestinal Diseases; Digestive System Neoplasms; Digestive System Diseases; Neoplasms by Site; Neoplasms by Histologic Type; Neoplasms, Squamous Cell; Carcinoma, Squamous Cell
Jiangxi Provincial Cancer Hospital
2022-06-02 PHASE2
NCT07746960 ACTIVE_NOT_RECRUITING
Hepatocellular Carcinoma Non-Resectable
Nanfang Hospital, Southern Medical University
2025-01-01 EARLY_PHASE1
NCT06102928 RECRUITING
Non-Small Cell Lung Cancer With Mutation in Epidermal Growth Factor Receptor
Kunming Medical University
2023-10-30
NCT05828953 ACTIVE_NOT_RECRUITING
Interstitial Lung Diseases
First Affiliated Hospital of Wenzhou Medical University
2021-09-28 PHASE2
NCT06043973 RECRUITING
Advanced Non-small Cell Lung Cancer
Qianfoshan Hospital
2023-09-01 PHASE3
NCT06469879 NOT_YET_RECRUITING
Small Cell Lung Cancer Limited Stage
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2024-09 PHASE3
NCT05188859 RECRUITING
Mesothelioma, Malignant; Mesothelioma, Malignant Pleural; Mesothelioma Malignant Advanced
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
2024-09-01 PHASE2
NCT06634667 NOT_YET_RECRUITING
Non-small Cell Lung Cancer
Hunan Province Tumor Hospital
2024-11-30 PHASE2
NCT06853769 ACTIVE_NOT_RECRUITING
Colorectal Cancer
The First Affiliated Hospital with Nanjing Medical University
2024-09-01 EARLY_PHASE1
NCT05742620 NOT_YET_RECRUITING
Adjuvant Treatment
Xijing Hospital
2023-06-20
NCT06456138 NOT_YET_RECRUITING
KRAS Mutation-Related Tumors; Advanced Lung Cancer; Refractory Tumor
Shanghai Chest Hospital
2024-07-01 PHASE1; PHASE2
NCT05214222 RECRUITING
Advanced Esophageal Squamous Cell Carcinoma
Nanfang Hospital, Southern Medical University
2022-09-02 PHASE2
NCT06939452 ACTIVE_NOT_RECRUITING
Advanced Gastric or Gastroesophageal Junction (G/GEJ) Adenocarcinoma
Yongxu Jia
2023-06-07 PHASE2
NCT06547476 NOT_YET_RECRUITING
Breast Cancer
Guangdong Provincial People's Hospital
2024-09-01 PHASE2
NCT06352008 RECRUITING
Non-Small Cell Lung Cancer
Tianjin Medical University Cancer Institute and Hospital
2024-07-01 PHASE2
NCT05913089 RECRUITING
Non Small Cell Lung Cancer
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2023-06-14 PHASE2
NCT06048315 NOT_YET_RECRUITING
Lung Cancer; TKI Resistance; EGFR Sensitive Mutation; Anlotinib; Pianzumab
Degan Lu
2023-09 PHASE3
NCT06327698 NOT_YET_RECRUITING
Melanoma
Hunan Cancer Hospital
2024-05-15 PHASE2
NCT06951841 NOT_YET_RECRUITING
Small Cell Lung Cancer
China Medical University, China
2025-04-30 PHASE4
NCT06441344 NOT_YET_RECRUITING
SCLC; Maintenance Treatment
Taizhou Hospital
2024-07-01 PHASE3
NCT06258642 RECRUITING
Small Cell Lung Cancer Recurrent
Fudan University
2024-04-17
NCT06970145 RECRUITING
Craniopharyngiomas
Nanfang Hospital, Southern Medical University
2025-04-25 PHASE1; PHASE2
NCT06897579 TERMINATED
Extensive Stage Small Cell Lung Cancer
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2025-04-07 PHASE2
NCT06886347 RECRUITING
Metastatic Nasopharyngeal Carcinoma
Chen Xiaozhong
2023-07-07 PHASE1
NCT07376499 NOT_YET_RECRUITING
Small Cell Lung Cancer
China Medical University, China
2026-01-25 PHASE2
NCT06901622 ENROLLING_BY_INVITATION
Gallbladder Cancer and Extrahepatic Cholangiocarcinoma
The First Affiliated Hospital of Zhengzhou University
2024-11-08 PHASE2
NCT05736952 WITHDRAWN
Platinum-resistant Ovarian Cancer
Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
2023-03-01 PHASE2
NCT05942508 UNKNOWN
Limited Stage Small Cell Lung Cancer; Not Progressed After First-line Chemoradiotherapy
Jinming Yu
2023-05-30 PHASE1
NCT07037680 RECRUITING
Locally Advanced Non-Small Cell Lung Cancer; Thoracic Radiotherapy; Safety
JIANYANG WANG
2024-01-01 PHASE2
NCT06182761 NOT_YET_RECRUITING
NSCLC
Shanghai Zhongshan Hospital
2024-01 PHASE2
NCT06483672 NOT_YET_RECRUITING
Adenocarcinoma of Lung Metastatic to Brain
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
2024-07 PHASE2
NCT05685550 ACTIVE_NOT_RECRUITING
Progression Free Survival(PFS)
Tianjin Medical University Cancer Institute and Hospital
2023-04-12 PHASE2
NCT06354530 RECRUITING
Neoadjuvant Therapy; Esophageal Squamous Cell Carcinoma
Army Medical Center of PLA
2024-03-08 PHASE2; PHASE3
NCT06379087 RECRUITING
Non-Small Cell Lung Cancer
Ji Yongling
2024-05-01 PHASE2
NCT06621095 NOT_YET_RECRUITING
Pancreatic Cancer; First-line; Metastatic Pancreatic Cancer
RenJi Hospital
2024-10-30 PHASE2
NCT06211790 RECRUITING
Kidney Cancer; Renal Cell Carcinoma; Renal Clear Cell Carcinoma
Fudan University
2024-01-16 PHASE2
NCT06355609 RECRUITING
Non-small Cell Lung Cancer
Hunan Province Tumor Hospital
2024-07-01 PHASE2
NCT05301764 COMPLETED
Soft Tissue Sarcoma
Lyvgen Biopharma Holdings Limited
2022-05-25 PHASE1; PHASE2
NCT06699498 NOT_YET_RECRUITING
Head and Neck Squamous Cell Carcinoma; Neoadjuvant Therapy; PD-L1; Anlotinib
The First Affiliated Hospital with Nanjing Medical University
2024-12-03 PHASE2
NCT05550558 NOT_YET_RECRUITING
Endometrial Cancer
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
2022-11-01 PHASE2
NCT05817214 RECRUITING
Cervical Cancer
Zhongnan Hospital
2023-02-16 PHASE2
NCT06585644 NOT_YET_RECRUITING
Lung Cancer (NSCLC)
Shanghai Pulmonary Hospital, Shanghai, China
2024-10-01 PHASE2
NCT05844813 ENROLLING_BY_INVITATION
Retroperitoneal Sarcoma
Peking University International Hospital
2022-11-01 PHASE4
NCT06348927 RECRUITING
Non-Small Cell Lung Cancer
Hunan Province Tumor Hospital
2024-07-01 PHASE2
NCT04172805 COMPLETED
Sarcoma,Soft Tissue
Sun Yat-sen University
2020-03-13 PHASE2
NCT06031480 UNKNOWN
Hepatocellular Carcinoma
Shanghai Zhongshan Hospital
2023-10-31 PHASE2
NCT06678230 UNKNOWN
Breast Cancer
The First Hospital of Jilin University
2024-11 PHASE2
NCT06086197 RECRUITING
Diffuse Large B-cell Lymphoma Recurrent; Diffuse Large B Cell Lymphoma Refractory
Zhejiang Cancer Hospital
2023-10-01 PHASE2
NCT04772001 UNKNOWN
Uterine Cervical Neoplasms; Chemoradiotherapy; Angiogenesis
Zhongnan Hospital
2021-03-12
NCT06188650 RECRUITING
Non-Small Cell Lung Cancer
Ningbo Medical Center Lihuili Hospital
2023-12-09
NCT04807166 ACTIVE_NOT_RECRUITING
Ovarian Neoplasms; Fallopian Tube Neoplasms; Neoplasms by Site; Genital Neoplasms, Female; Neoplasms, Glandular and Epithelial; Neoplasms by Histologic Type; Carcinoma, Ovarian Epithelial; Ovarian Diseases; Genital Diseases, Female; Endocrine System Diseases; Carcinoma; Anlotinib; Angiogenesis; Antineoplastic Agents; Tyrosine Kinase Inhibitor
Wenjun Cheng
2021-08-24 PHASE2
NCT06660511 RECRUITING
Ovarian Cancer Recurrent
Second Xiangya Hospital of Central South University
2024-10-15 EARLY_PHASE1
NCT06396585 UNKNOWN
Immunotherapy Gastroesophageal Junction
Fujian Cancer Hospital
2024-08-01 PHASE2
NCT06605690 NOT_YET_RECRUITING
Breast Cancer
Liu Shu
2024-10-31
NCT06222944 UNKNOWN
Gastric Cancer; Adenocarcinoma of Esophagogastric Junction
Peking University
2024-02-25 PHASE2
NCT05990231 UNKNOWN
Esophageal Squamous Cell Carcinoma
Second Affiliated Hospital, Zhejiang University, School of Medicine
2023-09-01 PHASE2
NCT06475287 UNKNOWN
Hepatocellular Carcinoma
Fudan University
2024-07-20 PHASE2
NCT06033118 UNKNOWN
Combined Hepatocellular Cholangiocarcinoma
Sichuan University
2023-10-01 PHASE1; PHASE2
NCT05807880 ACTIVE_NOT_RECRUITING
Nasopharyngeal Neoplasms
Sun Yat-sen University
2023-09-01 PHASE2
NCT05375734 COMPLETED
Pulmonary Pleomorphic Carcinoma; Immunotherapy; Tislelizumab
Second Affiliated Hospital of Nanchang University
2021-08-17 PHASE2
NCT06051851 UNKNOWN
Pancreatic Adenocarcinoma Metastatic
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
2023-07-01 PHASE2
NCT06438783 TERMINATED
Osteosarcoma; Other Solid Tumors
Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd.
2024-02-15 PHASE1
NCT06475755 NOT_YET_RECRUITING
Non-Small Cell Lung Cancer; Anti Angiogenesis
Tang-Du Hospital
2024-06-30 PHASE2
NCT05975645 TERMINATED
Advanced Hepatocellular Carcinoma
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2023-08-15 PHASE1
NCT04523272 ACTIVE_NOT_RECRUITING
Advanced Renal Cancer
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2020-08-25 PHASE3
NCT05218759 UNKNOWN
Non-Small Cell Lung Cancer
Shanghai Chest Hospital
2022-02-21
NCT05229003 UNKNOWN
Metastatic Colorectal Cancer
Fudan University
2022-03-09 PHASE2
NCT05842018 UNKNOWN
Non Small Cell Lung Cancer Recurrent
Tianjin Medical University Cancer Institute and Hospital
2023-05-01 PHASE2
NCT06426797 NOT_YET_RECRUITING
Locally Advanced Esophageal Squamous Cell Carcinoma
Peking University People's Hospital
2024-05 PHASE2
NCT05481775 WITHDRAWN
Locally Advanced Non-small Cell Lung Cancer; Efficacy and Safety
Sun Yat-sen University
2022-04-01 PHASE2
NCT06586242 RECRUITING
Esophageal Cancer
Xijing Hospital
2023-04-03 PHASE2
NCT05778149 NOT_YET_RECRUITING
Aumolertinib; Anlotinib; TP53; NSCLC; EGFR Activating Mutation
Tianjin Medical University Cancer Institute and Hospital
2023-03-31 PHASE2
NCT04914390 UNKNOWN
Triple-negative Breast Cancer
Sichuan Provincial People's Hospital
2023-09-15 PHASE2
NCT05193188 UNKNOWN
Chondrosarcoma
Second Affiliated Hospital, Zhejiang University, School of Medicine
2023-02-06 PHASE2
NCT06010901 UNKNOWN
Colorectal Cancer
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2024-01-13 PHASE1
NCT06221462 NOT_YET_RECRUITING
Carcinoma, Non-Small-Cell Lung
Ningbo No.2 Hospital
2024-02-01 PHASE2
NCT05021328 COMPLETED
NSCLC
Hubei Cancer Hospital
2021-10-01 PHASE1
NCT05001971 COMPLETED
Small Cell Lung Cancer
Hunan Cancer Hospital
2021-01-30 PHASE2
NCT05271916 RECRUITING
Non-Small Cell Lung Cancer (NSCLC)
Shanghai Chest Hospital
2022-10-13 PHASE1; PHASE2
NCT05193617 ACTIVE_NOT_RECRUITING
Nasopharyngeal Carcinoma
Sun Yat-sen University
2022-01-20 PHASE2
NCT06015126 UNKNOWN
Breast Cancer
Yan Xue
2022-10-05
NCT05539118 NOT_YET_RECRUITING
Melanoma
Xijing Hospital
2022-09-30 PHASE1; PHASE2
NCT05218629 UNKNOWN
Overall Survival
Qingdao Central Hospital
2022-01-01 PHASE2
NCT05028504 UNKNOWN
Gynecological Cancer
Sichuan Cancer Hospital and Research Institute
2022-05-10 PHASE2
NCT05029102 UNKNOWN
Gastric Cancer
Zhejiang University
2021-09-01 PHASE2
NCT05896059 UNKNOWN
Extensive Stage Small Cell Lung Cancer
Zhejiang Cancer Hospital
2023-05-15 PHASE2
NCT03646968 UNKNOWN
Non-Squamous Non Small Cell Lung Cancer
Yongchang Zhang
2018-08-01 PHASE2
NCT04854668 ACTIVE_NOT_RECRUITING
Metastatic Colorectal Cancer
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2021-05-27 PHASE3
NCT06000033 UNKNOWN
Breast Cancer
Qilu Hospital of Shandong University
2023-08-10 PHASE2
NCT06341530 UNKNOWN
Non-small Cell Lung Cancer
The First Affiliated Hospital of Zhengzhou University
2024-01-31 PHASE2
NCT05681390 UNKNOWN
Pancreatic Neoplasms
First Affiliated Hospital Xi'an Jiaotong University
2023-01-01 PHASE2
NCT05816499 UNKNOWN
NSCLC Stage IV; NSCLC Stage IIIB; NSCLC Stage IIIC
Shanghai Chest Hospital
2023-02-16 PHASE1; PHASE2
NCT05659186 UNKNOWN
Thyroid Cancer
West China Hospital
2022-12-30 PHASE2
NCT06062563 UNKNOWN
Locally Advanced or Metastatic Radioiodine-refractory Differentiated Thyroid Carcinoma
Peking Union Medical College Hospital
2023-11-11
NCT04891900 UNKNOWN
Gastric Cancer; Adenocarcinoma of Esophagogastric Junction
Henan Cancer Hospital
2021-05-10
NCT06482086 RECRUITING
Locally Advanced Thyroid Gland Carcinoma
West China Hospital
2021-06-01 PHASE2
NCT06277674 UNKNOWN
Non-small Cell Lung Cancer
Guangzhou University of Traditional Chinese Medicine
2023-11-02 PHASE2
NCT05715398 UNKNOWN
Non-Small Cell Lung Cancer
Shanghai Gopherwood Biotech Co., Ltd.
2023-02 PHASE1; PHASE2
NCT05494060 RECRUITING
Carcinoma; Gastrointestinal Diseases; Stomach Cancer; Gastroesophageal-junction Cancer; Digestive System Diseases; Gastric Cancer; Gastrointestinal Neoplasms
The First Affiliated Hospital with Nanjing Medical University
2022-03-16 PHASE2
NCT05220267 ACTIVE_NOT_RECRUITING
Non Clear Cell Renal Carcinoma
Sun Yat-sen University
2022-02-28 PHASE2
NCT05007093 ACTIVE_NOT_RECRUITING
DTC - Differentiated Thyroid Cancer
Yansong Lin
2020-12-01 PHASE2
NCT05996484 UNKNOWN
Esophageal Carcinoma; Neoadjuvant Therapy
Nanfang Hospital, Southern Medical University
2023-09 PHASE2
NCT04278222 UNKNOWN
Gastric Cancer; Immunotherapy; Anlotinib; Toripalimab
Shanghai Changzheng Hospital
2020-02-10 PHASE2
NCT05656222 WITHDRAWN
Objective Response; Overall Survival
Peking University People's Hospital
2021-08-01
NCT05718167 UNKNOWN
Advanced Squamous Non-Small Cell Lung Carcinoma
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2023-02 PHASE3
NCT05145218 UNKNOWN
Recurrent Platinum-resistant Ovarian Cancer
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2021-09-28 PHASE3
NCT02584478 UNKNOWN
Endometrial Carcinoma; Ovarian Carcinoma; Fallopian Tube Carcinoma; Primary Peritoneal Carcinoma; Cervical Carcinoma
Advenchen Laboratories, LLC
2015-12 PHASE3
NCT05460195 UNKNOWN
Non-small Cell Lung Cancer; Minimal Residual Disease; Immunotherapy; Anti-angiogenesis
Shanghai Chest Hospital
2022-01-01 PHASE2
NCT04691388 COMPLETED
NSCLC
Zhejiang Cancer Hospital
2021-03-01 PHASE2
NCT05296577 UNKNOWN
Breast Cancer
Henan Cancer Hospital
2022-03-22 PHASE2
NCT05558722 ACTIVE_NOT_RECRUITING
Breast Cancer Stage II
Xijing Hospital
2022-12-05 PHASE2
NCT05862337 RECRUITING
Hepatocellular Carcinoma
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2023-05-10 PHASE3
NCT05490667 UNKNOWN
Desmoid
Henan Cancer Hospital
2022-08-20
NCT04888546 UNKNOWN
Patients With Resectable Hepatocellular Carcinoma Who Are at High Risk of Recurrence or Metastasi
Chinese Academy of Medical Sciences
2021-04-30 PHASE1; PHASE2
NCT04660097 COMPLETED
SCLC, Extensive Stage
Henan Cancer Hospital
2021-05-20 PHASE2
NCT04770688 COMPLETED
Non-Small Cell Lung Cancer With EGFR Mutation; Locally Advanced Solid Tumor; Metastatic Cancer; Adenocarcinoma of Lung
Shanghai Chest Hospital
2020-11-19 PHASE1; PHASE2
NCT06611657 ACTIVE_NOT_RECRUITING
Whole Brain Radiotherapy
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
2021-08-20 PHASE2
NCT05772377 UNKNOWN
To Evaluate the Efficacy and Safety of Anlotinib Combined With Concurrent Chemoradiotherapy in the Treatment of Locally Advanced Cervical Cancer
The First Affiliated Hospital with Nanjing Medical University
2023-07-01 PHASE2
NCT04985851 UNKNOWN
Extensive-Stage Small-Cell Lung Cancer
Shanghai Chest Hospital
2021-09-28
NCT05121350 UNKNOWN
Soft Tissue Sarcoma
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2022-03 PHASE3
NCT04975451 UNKNOWN
Breast Cancer
Anqin Zhang
2021-10-01 PHASE2
NCT05493995 COMPLETED
Pancreatic Neoplasms
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
2022-07-21 PHASE2
NCT05866510 UNKNOWN
Esophageal Cancer
Peking University
2023-05-15 PHASE2
NCT05306847 UNKNOWN
Carcinoma, Non-Small-Cell Lung
Peking Union Medical College Hospital
2022-04-01 PHASE2
NCT06331169 Not yet recruiting
Breast Cancer
Fudan University
2024-04-01 Phase 1
NCT04963088 COMPLETED
Gastric Cancer
The First Affiliated Hospital with Nanjing Medical University
2021-03-06 PHASE1; PHASE2
NCT05038813 UNKNOWN
Esophageal Squamous Cell Carcinoma
The First Affiliated Hospital of Zhengzhou University
2022-03-14 PHASE2
NCT05137171 UNKNOWN
Cervical Cancer
The First Affiliated Hospital of Zhengzhou University
2022-03-01 PHASE2
NCT05244993 UNKNOWN
Breast Neoplasm Female
Liaoning Cancer Hospital & Institute
2022-07 PHASE2
NCT05385068 UNKNOWN
Epithelial Ovarian Cancer
Peking Union Medical College Hospital
2022-06 PHASE2
NCT04803851 UNKNOWN
Anlotinib; Anti-PD-1 Antibody; Advanced Pancreatic Cancer
Peking Union Medical College Hospital
2021-05-12 PHASE1; PHASE2
NCT05481645 TERMINATED
Advanced Endometrial Cancer; Sarcoma of Uterus
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2022-08-26 PHASE2
NCT05800080 UNKNOWN
Gastric Cancer
Xijing Hospital
2023-04
NCT05111366 UNKNOWN
Hepatocellular Carcinoma; Adjuvant Therapy
Xianhai Mao
2022-01-06 PHASE2
NCT04197492 UNKNOWN
Malignant Glioma
Huashan Hospital
2019-12-16 PHASE2
NCT04842526 UNKNOWN
Refractory or Recurrent Neuroblastoma in Children
Tianjin Medical University Cancer Institute and Hospital
2021-04-12 PHASE2
NCT04762030 UNKNOWN
Non Small Cell Lung Cancer
Shanghai Pulmonary Hospital, Shanghai, China
2021-02-08 PHASE2
NCT05400070 ACTIVE_NOT_RECRUITING
Sintilimab; Lung Cancer; Anlotinib; Chemotherapy
Tang-Du Hospital
2021-03-01 PHASE2
NCT05883085 UNKNOWN
Pheochromocytoma; Paraganglioma
Peking Union Medical College Hospital
2022-05-01 PHASE2
NCT05262335 UNKNOWN
Gastrointestinal Tumors
Ruijin Hospital
2021-12-01 PHASE2
NCT04620473 WITHDRAWN
Neoadjuvant Treatment; Rectal Cancer; Anlotinib
Shanghai Minimally Invasive Surgery Center
2023-11-01 PHASE2
NCT05124431 UNKNOWN
Renal Cell Carcinoma
Fudan University
2021-12 PHASE2
NCT05346952 UNKNOWN
Advanced Non-squamous Non-small Cell Lung Cancer
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2022-01-25 PHASE3
NCT05068206 UNKNOWN
Unresectable Metastatic Colorectal Cancer
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2021-10-08 PHASE2
NCT04895930 UNKNOWN
Non-Small-Cell Lung Cancer
Shanghai Chest Hospital
2021-10-12 PHASE2
NCT05193604 TERMINATED
Pancreatic Carcinoma
Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd.
2022-03-24 PHASE1
NCT04574284 COMPLETED
Advanced Endometrial Cancer
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2020-09-29 PHASE2
NCT04385550 UNKNOWN
Advanced Gastric and Gastro-oesophageal Junction Adenocarcinoma
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2020-05-20 PHASE3
NCT04646330 COMPLETED
NSCLC
Akeso
2020-11-18 PHASE1; PHASE2
NCT04860700 COMPLETED
Malignant Adrenal Gland Pheochromocytoma; Malignant Paraganglioma; Pheochromocytoma, Metastatic; Paraganglioma, Malignant; Paraganglioma, Extra-Adrenal
Peking Union Medical College Hospital
2021-04-30 PHASE2
NCT05812430 UNKNOWN
Advanced Biliary Tract Cancer
The First Affiliated Hospital of Zhengzhou University
2023-04-10 PHASE2
NCT04996758 COMPLETED
Nasopharyngeal Carcinoma; Recurrent or Metastatic Nasopharyngeal Carcinoma
Sun Yat-sen University
2021-10-30 PHASE2
NCT05087602 UNKNOWN
Locally Advanced or Metastatic Acral Malignant Melanoma
Qilu Hospital of Shandong University
2021-11-01 PHASE2
NCT04271813 COMPLETED
Colorectal Cancer; Immunotherapy; Anlotinib; Sintilimab; Chemo-free Therapy; First-line Treatment
Shanghai Changzheng Hospital
2020-06-01 PHASE2
NCT05600998 UNKNOWN
Ovarian Clear Cell Carcinoma
Peking University Third Hospital
2022-10-30
NCT05485350 UNKNOWN
Non-Small Cell Lung Cancer
Peking University Third Hospital
2022-09-12 PHASE2
NCT05133349 UNKNOWN
Advanced or Metastatic Paraganglioma/ Pheochromocytoma
Nanjing First Hospital, Nanjing Medical University
2021-09-14 PHASE2
NCT04790409 COMPLETED
Lung Cancer
Zhejiang Cancer Hospital
2019-08-01 PHASE2
NCT05030077 UNKNOWN
Urothelial Carcinoma; Anlotinib; Urogenital Neoplasms; Cisplatin; Carboplatin; Gemcitabine; Antineoplastic Agents
Tianjin Medical University Second Hospital
2021-10-01 PHASE2
NCT04877821 COMPLETED
Triple Negative Breast Cancer
Guangdong Provincial People's Hospital
2021-09-15 PHASE2
NCT05075512 UNKNOWN
Breast Neoplasm Female
Zhejiang Cancer Hospital
2021-09-01 PHASE2
NCT06507891 TERMINATED
Non Small Cell Lung Cancer
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2020-07-06 PHASE1; PHASE2
NCT04797507 UNKNOWN
SHR-1210; Anlotinib; Advanced Esophageal Squamous Cell Cancer
Peking Union Medical College Hospital
2021-03 PHASE2
NCT04952493 UNKNOWN
Thyroid Cancer
Peking Union Medical College Hospital
2021-09-15 PHASE2
NCT04967079 COMPLETED
Non Small Cell Lung Cancer
Shanghai Chest Hospital
2021-08-01 PHASE1
NCT05549973 UNKNOWN
Multiple Myeloma
Institute of Hematology & Blood Diseases Hospital, China
2022-09 PHASE1
NCT04671303 COMPLETED
Lung Cancer
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
2021-01-01 PHASE2
NCT05385900 UNKNOWN
Gastric Cancer
Xijing Hospital
2022-06-30
NCT03866980 TERMINATED
Lung Cancer Non-small Cell Stage IV
Akeso
2018-11-27 PHASE3
NCT04936295 UNKNOWN
Breast Cancer
Sun Yat-sen University
2021-06-16 PHASE2
NCT05460481 UNKNOWN
Non Small Cell Lung Cancer
Hunan Cancer Hospital
2022-06-12 PHASE2
NCT05559242 UNKNOWN
Liver Dysfunction
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2022-10 PHASE1
NCT05033587 UNKNOWN
MGMT-Unmethylated Glioblastoma
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
2021-09 PHASE2
NCT04055792 COMPLETED
Extensive Disease Small Cell Lung Cancer
Henan Cancer Hospital
2019-09-11 PHASE2
NCT04846452 UNKNOWN
Metastatic NSCLC; Recurrent NSCLC; Advanced Non-Small Cell Squamous Lung Cancer
The First Affiliated Hospital with Nanjing Medical University
2021-06-01 PHASE2
NCT05121363 UNKNOWN
Endometrial Carcinoma
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2021-12 PHASE2
NCT05387109 UNKNOWN
NSCLC
Tang-Du Hospital
2022-06-30 PHASE4
NCT05322499 UNKNOWN
Stage IV Esophagus Squamous Cell Carcinoma
Zhejiang Cancer Hospital
2022-04-15 PHASE2
NCT04979585 UNKNOWN
Melanoma
Di Wu
2021-07-15 PHASE2
NCT03950518 UNKNOWN
HCC
The First Affiliated Hospital of Zhengzhou University
2019-04-10 PHASE3
NCT05344924 UNKNOWN
Hepatocellular Carcinoma
Zhongda Hospital
2022-10-12 PHASE2; PHASE3
NCT05311579 UNKNOWN
Ovarian Carcinoma; Survival Outcomes; Adverse Events; Niraparib; Anlotinib; CA125; Chemotherapy; Targeted Therapy; Recurrent Ovarian Cancer
Lei Li
2022-03-27 PHASE2
NCT04566952 UNKNOWN
Ovarian Cancer; Ovarian and Fallopian Tube Cysts and Neoplasms; Neoplasms by Site; Neoplasms; Genital Neoplasms, Female; Urogenital Neoplasms; Neoplasms, Glandular and Epithelial; Neoplasms by Histologic Type; Carcinoma, Ovarian Epithelial; Ovarian Diseases; Adnexal Diseases; Genital Diseases, Female; Carcinoma; Anlotinib; PARP Inhibitors; BRCA1 Mutation; Angiogenesis; Antineoplastic Agents; BRCA2 Mutation
Xiaoxiang Chen
2020-10-28 PHASE2
NCT06015061 Recruiting
Pheochromocytoma Metastatic|Ultrasonography|Paraganglioma Malignant|Pheochromocytoma Malignant
Peking Union Medical College Hospital
2023-03-01 --
NCT04846634 NOT_YET_RECRUITING
Resectable Locally Advanced Non-small Cell Lung Cancer
Tianjin Medical University Cancer Institute and Hospital
2021-08 PHASE2
NCT04718701 UNKNOWN
Pancreatic Neoplasm; Metastatic Pancreatic Cancer; Locally Advanced Pancreatic Adenocarcinoma
The First Affiliated Hospital with Nanjing Medical University
2021-04-01 PHASE2
NCT03940378 UNKNOWN
ICC
The First Affiliated Hospital of Zhengzhou University
2019-02-01 PHASE3
NCT04213118 UNKNOWN
Hepatocellular Carcinoma; TACE; Anlotinib
First Affiliated Hospital Xi'an Jiaotong University
2020-04-23 PHASE2
NCT05816499 Recruiting
NSCLC Stage IV|NSCLC Stage IIIB|NSCLC Stage IIIC
Shanghai Chest Hospital|The Affiliated Hospital of Qingdao University|Anhui Provincial Hospital|Zhejiang University
2023-02-16 Phase 1|Phase 2
NCT04999800 UNKNOWN
Head and Neck Squamous Cell Carcinoma
Shi Yuankai
2021-07-18 PHASE2
NCT05130515 COMPLETED
Platinum-resistant Recurrent Clear Cell Ovarian Cancer
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
2021-12-15 PHASE2
NCT04777162 UNKNOWN
Gastric Cancer; Colo-rectal Cancer
Peking University
2021-03 PHASE2
NCT05602415 UNKNOWN
Soft Tissue Sarcoma; High Risk of Recurrence; Anlotinib; Radiotherapy
Ruijin Hospital
2022-11 PHASE2
NCT04363255 UNKNOWN
Small Cell Lung Carcinoma
Taizhou Hospital
2020-05-01 PHASE2
NCT04507035 UNKNOWN
Head and Neck Cancer
Sun Yat-sen University
2020-09-01 PHASE4
NCT05453383 UNKNOWN
Hepatocellular Cancer
Shen Feng
2022-07-08 PHASE2
NCT04967625 UNKNOWN
Small Cell Lung Cancer Extensive Stage
Zhejiang Cancer Hospital
2021-07-26 PHASE2
NCT04765228 UNKNOWN
Stage III Adult Soft Tissue Sarcoma
Yong Chen
2020-04-01 PHASE2
NCT04827004 UNKNOWN
Diffuse Large B-cell Lymphoma
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2021-04 PHASE2
NCT04620837 UNKNOWN
Small Cell Lung Carcinoma
Chinese Academy of Medical Sciences
2020-11-01 PHASE2
NCT05035914 UNKNOWN
Advanced Colorectal Cancer
Guangzhou University of Traditional Chinese Medicine
2021-07-09 PHASE1; PHASE2
NCT04665609 UNKNOWN
Hepatocellular Carcinoma; Thermal Ablation; Anlotinib; PDL-1
Chinese PLA General Hospital
2021-03-05 PHASE3
NCT05013697 UNKNOWN
Esophageal Neoplasms
Henan Cancer Hospital
2021-09 PHASE2
NCT05232552 UNKNOWN
Nasopharyngeal Carcinoma
Zhejiang Cancer Hospital
2021-01-01 PHASE2
NCT04757779 UNKNOWN
Relapsed Small Cell Lung Cancer; Anlotinib
First People's Hospital of Hangzhou
2019-12-30 PHASE2
NCT04659733 UNKNOWN
Sarcoma
Yizhuo Zhang
2020-12-30 PHASE1
NCT04438902 TERMINATED
Non Small Cell Lung Cancer
First Affiliated Hospital of Zhejiang University
2020-12-12 PHASE2
NCT04725214 UNKNOWN
MGMT-Unmethylated Glioblastoma
Second Affiliated Hospital, Zhejiang University, School of Medicine
2021-01-15 PHASE2
NCT04325763 UNKNOWN
Stage III Non-small-cell Lung Cancer
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2020-05-27 PHASE3
NCT04964479 UNKNOWN
Non Small Cell Lung Cancer
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2021-08-06 PHASE3
NCT04291248 UNKNOWN
MSI-H or dMMR Advanced Solid Tumors
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2020-03 PHASE2
NCT04157478 UNKNOWN
Glioblastoma
People's Hospital of Guangxi Zhuang Autonomous Region
2020-01 PHASE2
NCT05311319 UNKNOWN
Hepatocarcinoma
Fudan University
2022-01-11 PHASE2
NCT04234607 UNKNOWN
Extensive Small Cell Lung Cancer
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2020-01 PHASE3
NCT05027100 UNKNOWN
Small Cell Lung Cancer (SCLC)
Haibo Zhang
2021-09-30
NCT04822805 UNKNOWN
Recurrent High-grade Glioma
First People's Hospital of Hangzhou
2020-04-13 PHASE2
NCT05198531 UNKNOWN
Recurrent / Metastatic Nasopharyngeal Cancer
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2022-01 PHASE1; PHASE2
NCT04924192 TERMINATED
Advanced Lung Carcinoma
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2021-08-18 PHASE2
NCT04547855 UNKNOWN
Glioblastoma
Yonggao Mou
2020-09-11 PHASE2
NCT04157140 UNKNOWN
Hepatocellular Carcinoma
Jinglong Chen
2019-11-28 PHASE2
NCT04544644 UNKNOWN
Non-small Cell Lung Cancer
Chinese PLA General Hospital
2020-09 PHASE2
NCT04471480 UNKNOWN
ESCC
Dong Wang
2020-09-01
NCT04720807 UNKNOWN
Platinum-resistant Recurrent Ovarian Cancer
Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
2020-09-01 PHASE2
NCT03890068 COMPLETED
Soft Tissue Sarcoma
Sun Yat-sen University
2019-04-11 PHASE2
NCT04119674 COMPLETED
Glioblastoma
Zhejiang Cancer Hospital
2019-03-19 PHASE1; PHASE2
NCT04970914 UNKNOWN
Colorectal Cancer
Peking Union Medical College Hospital
2021-11-05 PHASE2
NCT03946943 UNKNOWN
Soft Tissue Sarcomas; Undifferentiated Pleomorphic Sarcoma
Di Wu
2019-07-19 PHASE2
NCT04452370 UNKNOWN
Triple Negative Breast Cancer
Chinese Academy of Medical Sciences
2020-09-23 PHASE2
NCT04405505 UNKNOWN
Triple Negative Breast Cancer
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2020-06-01 PHASE3
NCT04731038 UNKNOWN
Advanced Cervical Cancer
Ruijin Hospital
2021-08-01 PHASE1
NCT04453423 UNKNOWN
Non-squamous Non-small-cell Lung Cancer
The First Affiliated Hospital with Nanjing Medical University
2020-07-01 PHASE2
NCT04668508 UNKNOWN
Malignant Brain Stem Tumor; Glioma
Zhejiang Cancer Hospital
2020-11-24 PHASE2
NCT03945799 TERMINATED
Hepatocellular Carcinoma
Zhejiang University
2019-04-22 PHASE1; PHASE2
NCT04736810 COMPLETED
Nasopharyngeal Carcinoma
Akeso
2021-02-25 PHASE2
NCT04731909 UNKNOWN
SCLC, Extensive Stage; Lung Cancer; Small Cell Lung Cancer
Third Military Medical University
2018-10-01
NCT03951571 COMPLETED
Soft Tissue Sarcoma Adult; High Grade Sarcoma
Fudan University
2019-05-13 PHASE2
NCT04172571 COMPLETED
Hepatocellular Carcinoma
Akeso
2018-11-22 PHASE2
NCT04080843 COMPLETED
Colorectal Cancer; RAS and BRAF Wild-type; Colorectal Neoplasms; Intestinal Neoplasms; Gastrointestinal Neoplasms; Digestive System Neoplasms; Neoplasms by Site; Neoplasms; Digestive System Diseases; Gastrointestinal Diseases; Colonic Diseases; Intestinal Diseases; Rectal Diseases
Zhejiang University
2019-11-15 PHASE2
NCT04933175 UNKNOWN
Extensive Stage Small Cell Lung Cancer
Liu Zhenhua
2021-06 PHASE2
NCT04624711 UNKNOWN
HER2-negative Breast Cancer
The First Affiliated Hospital with Nanjing Medical University
2021-03-01 PHASE2
NCT04978753 UNKNOWN
Non-small Cell Lung Cancer; Brain Metastases
Li-kun Chen
2021-05-01 PHASE2
NCT04358562 UNKNOWN
Non-small Cell Lung Cancer; EGFR Gene Mutation
Second Affiliated Hospital of Nanchang University
2020-05-01 PHASE2
NCT05883085 Recruiting
Pheochromocytoma|Paraganglioma
Peking Union Medical College Hospital
2022-05-01 Phase 2
NCT05301764 Recruiting
Soft Tissue Sarcoma
Lyvgen Biopharma Holdings Limited
2022-05-25 Phase 1|Phase 2
NCT05206656 COMPLETED
Metastatic Breast Cancer
Hunan Cancer Hospital
2020-10-09 PHASE2
NCT04797806 UNKNOWN
Non Small Cell Lung Cancer
Tianjin Medical University Cancer Institute and Hospital
2021-03-12 PHASE3
NCT06015035 COMPLETED
Sintilimab and Anlotinib in Combination With Chemotherapy
Tang-Du Hospital
2021-04-01 PHASE2
NCT04316351 UNKNOWN
IIIb/IV NSCLC With T790M Positive Mutations Failed to Osimertinib Therapy
Guangzhou Institute of Respiratory Disease
2020-04-01 PHASE2
NCT04507906 COMPLETED
NSCLC Stage IV; Checkpoint Inhibitor
Shanghai Chest Hospital
2020-11-02 PHASE1; PHASE2
NCT04809142 UNKNOWN
Advanced Biliary Cancer
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2021-02-04 PHASE3
NCT04063683 UNKNOWN
Esophageal Squamous Cell Carcinoma
Henan Cancer Hospital
2019-10-07 PHASE2
NCT04813406 UNKNOWN
Esophageal Squamous Cell Carcinoma
Henan Provincial People's Hospital
2021-03
NCT04236362 UNKNOWN
Gynecological Cancer
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2020-02-27 PHASE1; PHASE2
NCT04376073 UNKNOWN
Platinum-resistant Ovarian Cancer
Jihong Liu
2020-05-22 PHASE2
NCT03936452 COMPLETED
Natural Killer/T-Cell Lymphoma, Nasal and Nasal-Type; Early Stage; Anlotinib; Peg-aspargase; Sintilimab; Phase Two; Open; Radiotherapy
Sun Yat-sen University
2019-04-28 PHASE2
NCT04147728 UNKNOWN
Stereotactic Body Radiation Therapy
Peking University Third Hospital
2019-12-24 PHASE2
NCT03387904 UNKNOWN
Esophageal Squamous Cell Carcinoma
The First Affiliated Hospital of Zhengzhou University
2019-01-13 PHASE2
NCT04958993 TERMINATED
Non-small Cell Lung Cancer
Shandong Cancer Hospital and Institute
2020-11-12 PHASE1; PHASE2
NCT04164745 UNKNOWN
NSCLC
Peking Union Medical College Hospital
2019-11-16 PHASE2
NCT03743129 COMPLETED
Non-Small Cell Lung Cancer Stage III
Anhui Shi, MD
2019-04-12 PHASE2
NCT04764084 UNKNOWN
HER2-negative Breast Cancer; Gastric Adenocarcinoma; Cholangiocarcinoma; Pancreatic Cancer
Peking University Cancer Hospital & Institute
2021-04-01 PHASE1
NCT03755869 UNKNOWN
Non-squamous NSCLC
First Affiliated Hospital Xi'an Jiaotong University
2018-11-29 PHASE4
NCT04042597 UNKNOWN
Effect of Drugs; Quality of Life; Chordoma; Advanced Cancer
Peking University People's Hospital
2019-07-18 PHASE2
NCT04619537 UNKNOWN
Non Small Cell Lung Cancer
Shandong Cancer Hospital and Institute
2020-10-08 PHASE2
NCT04619563 UNKNOWN
Non Small Cell Lung Cancer
Shandong Cancer Hospital and Institute
2020-11-04 PHASE2
NCT04684017 UNKNOWN
SCLC; Anlotinib
Shanghai Chest Hospital
2019-05-01 PHASE2
NCT03639467 UNKNOWN
Recurrent Nasopharyngeal Carcinoma; Metastatic Nasopharyngeal Carcinoma
Chinese Academy of Medical Sciences
2018-09-18 PHASE1; PHASE2
NCT04181372 UNKNOWN
Stage III Non-small-cell Lung Cancer
The First Affiliated Hospital of Guangzhou Medical University
2019-12 PHASE2
NCT04073550 UNKNOWN
Small Cell Lung Cancer
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2019-10-31 PHASE3
NCT04073537 UNKNOWN
Squamous Non-small Cell Lung Cancer
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2019-10-31 PHASE3
NCT04211896 UNKNOWN
Non Small Cell Lung Cancer
The First Affiliated Hospital with Nanjing Medical University
2020-01-01 PHASE2
NCT04882033 UNKNOWN
Small Cell Lung Cancer Limited Stage
Tianjin Medical University Cancer Institute and Hospital
2021-05-07 PHASE1
NCT04007835 UNKNOWN
NSCLC
Guangdong Association of Clinical Trials
2019-07
NCT04439890 UNKNOWN
Advanced Non-squamous Cell Non-small Cell Lung Cancer
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2019-08-08 PHASE3
NCT03720873 UNKNOWN
EGFR Gene Mutation
Fujian Cancer Hospital
2018-10 PHASE2
NCT04066543 UNKNOWN
Carcinoma, Hepatocellular
Zhejiang Cancer Hospital
2019-08-30 PHASE2
NCT04182698 UNKNOWN
Patients With Non-small Cell Lung Cancer
Second Affiliated Hospital of Xi'an Jiaotong University
2019-11-22 PHASE1; PHASE2
NCT03618238 COMPLETED
Natural Killer/T-Cell Lymphoma, Nasal and Nasal-Type
Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
2018-07-25 PHASE2
NCT03924882 UNKNOWN
Ovarian Cancer
Second Affiliated Hospital, Zhejiang University, School of Medicine
2019-04-25 PHASE2
NCT04124731 UNKNOWN
Carcinoma; Non-small Cell Lung Cancer
Shanghai Chest Hospital
2019-10 PHASE2
NCT03880695 UNKNOWN
Sarcoma
Peking University People's Hospital
2019-03 PHASE2
NCT03706287 UNKNOWN
Lung Cancer Metastatic
Sichuan Cancer Hospital and Research Institute
2018-12-06 PHASE1; PHASE2
NCT04192682 UNKNOWN
Small Cell Lung Cancer
Changzhou Cancer Hospital of Soochow University
2019-05-08 PHASE2; PHASE3
NCT03906058 COMPLETED
Nasopharyngeal Carcinoma
Sun Yat-sen University
2019-04-29 PHASE2
NCT04309136 UNKNOWN
Thyroid Cancer
Fudan University
2019-06-01 PHASE2
NCT04503967 UNKNOWN
Gastric Adenocarcinoma; Esophageal Squamous Cell Carcinoma
Shanghai Zhongshan Hospital
2020-08-01 PHASE2
NCT04314297 UNKNOWN
Anlotinib; Durvalumab; Small Cell Lung Cancer
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
2020-04 PHASE2
NCT04313660 UNKNOWN
NSCLC; Anlotinib; PD-1/L1 Inhibitor
Xiaorong Dong
2020-04 PHASE2
NCT04080154 UNKNOWN
Hepatocellular Carcinoma
Shanghai Zhongshan Hospital
2019-09-24 PHASE2
NCT04223583 COMPLETED
Soft Tissue Sarcomas
Henan Cancer Hospital
2019-06-26 PHASE4
NCT04273815 UNKNOWN
Non-small Cell Lung Cancer
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2020-07-06 PHASE1; PHASE2
NCT03825705 UNKNOWN
Advanced Biliary Adenocarcinoma/Hepatocellular Carcinoma
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2019-04-23 PHASE1; PHASE2
NCT03736837 COMPLETED
Non Small Cell Lung Cancer
Tianjin Medical University Cancer Institute and Hospital
2018-12-01 PHASE2
NCT04300959 UNKNOWN
Biliary Tract Cancer
Zhejiang Cancer Hospital
2020-01-01 PHASE2
NCT04207463 UNKNOWN
Gastrointestinal Tumors, Urinary System Tumors, Neuroendocrine Tumors
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2020-06-03 PHASE2
NCT04203719 UNKNOWN
Advanced Head, Neck and Chest Cancer
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2020-05-09 PHASE2
NCT03998085 UNKNOWN
Non-Small Cell Lung Cancer
The First Hospital of Jilin University
2019-03-05
NCT03910127 UNKNOWN
Non-small Cell Lung Cancer
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2019-06-11 PHASE1
NCT04157491 UNKNOWN
Endometrial Cancer
Sun Yat-sen University
2019-10-18 PHASE1; PHASE2
NCT03996408 UNKNOWN
Advanced Cholangiocarcinoma
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2019-06-24 PHASE1; PHASE2
NCT03769805 UNKNOWN
Nonsmall Cell Lung Cancer
The First Affiliated Hospital with Nanjing Medical University
2019-06-15
NCT04675697 UNKNOWN
Extensive-stage Small-cell Lung Cancer
Xiangya Hospital of Central South University
2019-01-24 PHASE2
NCT04611711 UNKNOWN
Patients With Digestive System Tumors Resistant to PD-1 Inhibitors
Peking University
2020-11-01 PHASE1; PHASE2
NCT03792542 UNKNOWN
Soft Tissue Sarcoma
Second Affiliated Hospital, Zhejiang University, School of Medicine
2019-01 PHASE2
NCT04028778 UNKNOWN
Lung Cancer, Nonsmall Cell
Sun Yat-sen University
2019-04-10 PHASE3
NCT03781869 UNKNOWN
Extensive-stage Small Cell Lung Cancer
Third Military Medical University
2018-12 PHASE2
NCT03750916 UNKNOWN
Non Small Cell Lung Cancer
Qilu Hospital of Shandong University
2018-11-30 PHASE2
NCT03700359 UNKNOWN
Small Cell Lung Carcinoma
The First Affiliated Hospital of Guangzhou Medical University
2019-03-01 PHASE2
NCT03983928 UNKNOWN
Lung Cancer
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2019-06-03 PHASE1; PHASE2
NCT03735264 UNKNOWN
Non Small Cell Lung Cancer
The Affiliated Hospital of Qingdao University
2018-11-15 PHASE2
NCT03790228 UNKNOWN
Non-squamous Cell Non-Small Cell Lung Cancer
Henan Cancer Hospital
2019-03-22 PHASE1
NCT04670107 COMPLETED
NSCLC; Angiogenesis; Immunotherapy
The Affiliated Hospital of Qingdao University
2018-06-01 PHASE1; PHASE2
NCT04232397 TERMINATED
Chronic Graft-versus-host-disease
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
2020-04-10 PHASE2
NCT04111913 UNKNOWN
Unresectable Stage III Non-small Cell Lung Cancer
Nanfang Hospital, Southern Medical University
2019-10-01 PHASE2
NCT03589950 UNKNOWN
Lung Neoplasms; Docetaxel; Pemetrexed; S-1; Anlotinib
The First People's Hospital of Lianyungang
2018-08-01 PHASE2
NCT03601975 UNKNOWN
Nasopharyngeal Carcinoma
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2018-08-27 PHASE3
NCT04004975 UNKNOWN
Recurrent Glioblastoma
Shandong Cancer Hospital and Institute
2019-06-25 PHASE1; PHASE2
NCT03929965 UNKNOWN
Advanced Solid Tumor
Shanghai Changzheng Hospital
2019-07-01
NCT03624309 UNKNOWN
Non-small Cell Lung Cancer
Hunan Cancer Hospital
2018-10-15 PHASE2
NCT03897283 UNKNOWN
Advanced Solid Tumors
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2019-06-20 PHASE1
NCT03855358 UNKNOWN
Triple Negative Breast Cancer (TNBC)
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2019-05-09 PHASE1
NCT03823118 COMPLETED
Small Cell Lung Cancer Recurrent
Taizhou Hospital
2019-03-01 PHASE2
NCT03975036 UNKNOWN
Advanced Solid Tumor
Henan Cancer Hospital
2019-04-08 PHASE2; PHASE3
NCT03732846 UNKNOWN
Recurrent Small Cell Lung Cancer
Peking University Cancer Hospital & Institute
2018-11-01 PHASE2
NCT03890055 UNKNOWN
Small Cell Lung Cancer
Chifeng Municipal Hospital
2019-04-01 PHASE4
NCT03991975 UNKNOWN
Advanced Acral Malignant Melanoma
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2019-06-11 PHASE1; PHASE2
NCT03416517 UNKNOWN
Ewing's Tumor Metastatic
Peking University People's Hospital
2018-01-22 PHASE1; PHASE2
NCT04029350 UNKNOWN
Non Small Cell Lung Cancer
Tianjin Medical University Cancer Institute and Hospital
2019-07-31 PHASE2
NCT04002284 COMPLETED
Breast Neoplasm; Antineoplastic Agents; Anlotinib
Peng Yuan
2018-07-12 PHASE2
NCT03780283 UNKNOWN
Carcinoma; Lung Neoplasm; Small Cell Lung Cancer
First Hospital of Shijiazhuang City
2019-01-01 PHASE2
NCT03527888 UNKNOWN
Neoplasm of Bone
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2018-01-31 PHASE2
NCT03778138 UNKNOWN
Non-squamous Cell Non-Small Cell Lung Cancer
Henan Provincial People's Hospital
2019-01-01 PHASE2
NCT03815474 UNKNOWN
Sarcoma, Soft Tissue
Liaoning Cancer Hospital & Institute
2019-05-20 PHASE2
NCT03765775 UNKNOWN
Carcinoma; Non-small Cell Lung Cancer; Lung Neoplasm
First Hospital of Shijiazhuang City
2018-11-20 PHASE2
NCT03591666 UNKNOWN
Head and Neck Carcinoma; Adenocarcinoma; Recurrent Disease; Distantly Metastatic Malignant Neoplasm
Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
2018-07-15 PHASE2
NCT03628521 UNKNOWN
Lung Cancer; Advanced Stage
Shanghai Chest Hospital
2018-07-20 PHASE1
NCT03766776 UNKNOWN
Cancer of Liver
The First Affiliated Hospital with Nanjing Medical University
2018-12-31
NCT04052152 UNKNOWN
Advanced Hepatocellular Carcinoma
The First Affiliated Hospital with Nanjing Medical University
2019-06-10 PHASE2
NCT03766490 UNKNOWN
Non-Small-Cell Lung
The First Affiliated Hospital of Soochow University
2019-03-30
NCT03841136 UNKNOWN
Extensive-stage Small Cell Lung Cancer
Fudan University
2019-04-01 PHASE2
NCT03799601 UNKNOWN
NSCLC
Tongji Hospital
2019-03-01 PHASE4
NCT02586337 UNKNOWN
Differentiated Thyroid Cancer
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2015-07 PHASE2; PHASE3
NCT03778853 UNKNOWN
Advanced Non-squamous NSCLC
LanZhou University
2019-01 PHASE4
NCT03768037 UNKNOWN
Advanced Non-squamous NSCLC
Guangdong Association of Clinical Trials
2018-11-26 PHASE4
NCT03545711 UNKNOWN
Colo-rectal Cancer
Chinese Academy of Medical Sciences
2018-05-26 PHASE1; PHASE2
NCT03732001 UNKNOWN
Non-small Cell Lung Cancer
China Medical University, China
2018-11-08 PHASE2
NCT04012619 COMPLETED
Non-squamous Non-small-cell Lung Cancer; Anlotinib
Sichuan University
2019-04-30 PHASE1
NCT03726736 UNKNOWN
Non-small Cell Lung Cancer
Yong Fang
2018-12-21 PHASE1; PHASE2
NCT03672136 UNKNOWN
Carcinoma, Non-Small-Cell Lung
Shandong Cancer Hospital and Institute
2018-11-01 PHASE2
NCT03728374 UNKNOWN
Non-Small-Cell Lung Cancer
First Affiliated Hospital of Wenzhou Medical University
2018-11-01 PHASE2
NCT03703596 UNKNOWN
Lung Cancer; Lung Cancer Metastatic
Sichuan Cancer Hospital and Research Institute
2018-10-16 PHASE2
NCT04106024 UNKNOWN
Gastrointestinal Stromal Tumors
Cttq
2018-10-23 PHASE2
NCT03654027 UNKNOWN
Non-small Cell Lung Cancer
First Affiliated Hospital of Guangxi Medical University
2018-10-01 PHASE2
NCT03671538 UNKNOWN
Non-squamous Non-small Cell Lung Cancer
Lingyu Luo
2018-10-01
NCT03457844 UNKNOWN
Gastroenteropancreatic Neuroendocrine Tumor G3
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2018-01-30 PHASE2
NCT03636685 UNKNOWN
NSCLC; Adenocarcinoma; Squamous Cell Carcinoma
Chinese Academy of Medical Sciences
2018-08-15 PHASE1; PHASE2
NCT05089643 UNKNOWN
Metastatic Triple-Negative Breast Cancer
Chinese Academy of Medical Sciences
2019-04-11 PHASE2
NCT04947371 WITHDRAWN
Hepatocellular Carcinoma
Shanghai Zhongshan Hospital
2018-12-15 PHASE2
NCT03602027 UNKNOWN
Non-squamous Non-small Cell Lung Cancer
Second Affiliated Hospital of Nanchang University
2018-08-01
NCT02586350 COMPLETED
Medullary Thyroid Carcinoma
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2015-07 PHASE2; PHASE3
NCT03566576 UNKNOWN
Non-squamous Non-small Cell Lung Cancer
Fujian Cancer Hospital
2018-07-01
NCT02825563 COMPLETED
Advanced Cancer
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2016-06 PHASE1
NCT02649361 COMPLETED
Esophageal Squamous Cell Carcinoma
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2016-01 PHASE2
NCT03059797 COMPLETED
Small Cell Lung Cancer
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2017-03-27 PHASE2
NCT02461407 UNKNOWN
Gastric Cancer
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2015-06 PHASE2; PHASE3
NCT02072044 UNKNOWN
Renal Cell Carcinoma
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2013-12 PHASE2
NCT02809534 UNKNOWN
Hepatocellular Carcinoma
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2016-09 PHASE2
NCT02752516 UNKNOWN
Cancer
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2016-04-27 PHASE1
NCT02449343 UNKNOWN
Soft Tissue Sarcoma
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2015-05-12 PHASE2; PHASE3
NCT02029209 UNKNOWN
Non-small Cell Lung Cancer
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2013-12 PHASE2; PHASE3
NCT02558348 TERMINATED
Endometrial Cancer; Ovarian Cancer; Cervical Cancer
Advenchen Laboratories, LLC
2015-11 PHASE1; PHASE2
NCT02388919 COMPLETED
Non-small Cell Lung Cancer
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2015-02-26 PHASE2; PHASE3
NCT02622932 COMPLETED
Advanced Solid Tumors
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2015-12-02 PHASE1
NCT01874873 COMPLETED
Tumor
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2013-04 PHASE2
NCT02072031 UNKNOWN
Anlotinib; RCC
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2013-12 PHASE2
NCT02332499 COMPLETED
Metastatic Colorectal Cancer
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2014-12 PHASE2; PHASE3
NCT01833923 COMPLETED
Advanced Cancer
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2011-05 PHASE1
NCT01878448 COMPLETED
Cancer
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2013-04 PHASE2
NCT01924195 COMPLETED
Non-small Cell Lung Cancer
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2013-08 PHASE2
NCT04216082 COMPLETED
Advanced Malignancy
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2013-08-01 PHASE2

(data from https://clinicaltrials.gov, updated on 2026-04-22)

Check the Anlotinib (AL3818) Dihydrochloride product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Compliance for Clinical Use

Mechanism and Biochemical Profile

Anlotinib selectively binds to and inhibits vascular endothelial growth factor receptor 2 (VEGFR2) with nanomolar potency, suppressing downstream receptor autophosphorylation and intracellular signal transduction pathways essential for endothelial cell proliferation and migration. This targeted inhibition impairs tumor neovascularization and disrupts vascular supply, thereby inducing tumor cell apoptosis and suppressing disease progression in clinical conditions such as non-small cell lung cancer, soft tissue sarcoma, and esophageal squamous cell carcinoma.

Appendix RUO and cGMP Quality Standards

Quality Dimension RUO (Research Use Only) cGMP (Current Good Manufacturing Practice)
Clinical Applicability Prohibited in human clinical trials or medical diagnostics. Mandatory for human clinical trials (Phase I–III) and therapies.
Regulatory Status Non-regulated grade; exempt from drug manufacturing laws. Legally enforced by health authorities (e.g., FDA, EMA, NMPA).
Facility Environment Unclassified analytical or research laboratories. Validated Cleanrooms (ISO Class 5–8) with continuous monitoring.
Quality Control Basic purity and activity testing. Rigorous safety release testing (Sterility, Endotoxin, Mycoplasma).
Process Validation Basic equipment calibration; no process validation required. Full qualification (IQ/OQ/PQ) and complete batch records.
Quality Assurance Vendor self-declared without required formal QMS. Mandatory QA/QC unit, Change Control, CAPA, and vendor audits.
Regulatory Impact High risk of IND rejection if used as a critical raw material. Required for IND/NDA filings, supported by Drug Master Files (DMF).

Footnotes

Regulatory Note: Governed by FDA (21 CFR Parts 210/211/312), EMA (EudraLex Vol 4), ICH Guidelines (E6/Q7/Q9/Q10), and compendial standards (USP <71>/<85>/<1043>).

Note: Technical data last updated: Sep 1, 2026.