Home Biosimilar Antibodies Proteases MMP antibody Andecaliximab (Anti-MMP9)
For research use only. Not for use in humans.

Andecaliximab (Anti-MMP9)

Synonyms: null

Andecaliximab (Anti-MMP9) is a recombinant chimeric IgG4 monoclonal antibody (mAb) that targets matrix metalloproteinase 9 (MMP9). Andecaliximab shows antifibrotic efficacy in idiopathic pulmonary fibrosis mouse models. MW: 145.5 kD.

Andecaliximab (Anti-MMP9)

Quality Control

Batch: Purity: 99% Protein concentration: 4.998mg/ml Endotoxin Level: ＜1EU/mg
99

Specificity

Name Citation MMP MMP1 MMP2 MMP3 MMP7 MMP8 MMP9 MMP12 MMP13 MMP14 MMP26 Others
Batimastat (BB-94) 41
Ilomastat (GM6001) 60
ARP 100 0
MMP-9-IN-1 7
T-26c 1
SB-3CT 30
Marimastat (BB-2516) 22
NSC 405020 5
SM-7368 0
CL-82198 1
Triolein 0 ROS,IL-6
Solasodine 0 miR-21,RECK,EMMPRIN
Isoliquiritin apioside 0 NF-κB,MAPK
T-5224 22 Adamts-5,IL-1β,c-Jun
AUDA 0 TNF-α,IL-1β,p38
o-Phenanthroline 1 Fe2+,Collagenase
Trans-Zeatin 0 JNK,ERK,p38 MAPK
(S,S)-TAPI-1 25 ADAM17/TACE
Nobiletin 16
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1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.

Mechanism of Action

Description
Andecaliximab (Anti-MMP9) is a recombinant chimeric IgG4 monoclonal antibody (mAb) that targets matrix metalloproteinase 9 (MMP9). Andecaliximab shows antifibrotic efficacy in idiopathic pulmonary fibrosis mouse models. MW: 145.5 kD.

Product Details

CAS No. 1518996-49-0
Molecular Weight 145.5 kDa
Isotype Human IgG4SP
Source CHO
Purification AKTA
Sterility 0.2 μM filtered
Formulation 100 mM Pro-Ac, 20mM Arg, pH5.0
Storage
(From the date of receipt)		 Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

Tech Support

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