SMILES:
CCN(CC)CCNC(=O)C1=C(NC(=C1C)C=C2C3=C(C=CC(=C3)C4=CSC(=N4)C5=CC=CC=C5)NC2=O)C
Chemical Structure
Check the
Amcasertib (BBI503)
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| IUPAC Name | N-[2-(diethylamino)ethyl]-2,4-dimethyl-5-[(Z)-[2-oxo-5-(2-phenyl-1,3-thiazol-4-yl)-1H-indol-3-ylidene]methyl]-1H-pyrrole-3-carboxamide | |
|---|---|---|
| CAS Number | 1129403-56-0 | |
| Molecular Formula |
C31H33N5O2S |
|
| Molecular Weight (MW) | 539.69 | |
| SMILES | CCN(CC)CCNC(=O)C1=C(NC(=C1C)C=C2C3=C(C=CC(=C3)C4=CSC(=N4)C5=CC=CC=C5)NC2=O)C | |
| InChIKey | QDWKGEFGLQMDAM-ULJHMMPZSA-N |
How to Prepare Stock Solution?
|
Concentration
Volume
Mass
|
|---|
Solubility
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
14 mg/mL
(25.94 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 1 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Jump to
- Amcasertib (BBI503) Clinical Trials
- Amcasertib (BBI503) Solubility in DMSO
- Amcasertib (BBI503) Stock Solution
- Amcasertib (BBI503) Storage
- Amcasertib (BBI503) Stability
- Amcasertib (BBI503) Molecular Weight
- Amcasertib (BBI503) CAS Number
- Amcasertib (BBI503) Chemical Structure (2D and 3D)
- Amcasertib (BBI503) SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.