Molecular Weight: 518.92 g/mol
Chemical Structure
Check the
Alisertib (MLN8237)
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
100 mg/mL
(192.7 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
35 mg/mL
(67.44 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
100 mg/mL
(192.7 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
33 mg/mL
(63.59 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
25 mg/mL
(48.17 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
| IUPAC Name | 4-[[9-chloro-7-(2-fluoro-6-methoxyphenyl)-5H-pyrimido[5,4-d][2]benzazepin-2-yl]amino]-2-methoxybenzoic acid | |
|---|---|---|
| CAS Number | 1028486-01-2 | |
| Molecular Formula |
C27H20ClFN4O4 |
|
| Molecular Weight (MW) | 518.92 | |
| SMILES | COC1=C(C(=CC=C1)F)C2=NCC3=CN=C(N=C3C4=C2C=C(C=C4)Cl)NC5=CC(=C(C=C5)C(=O)O)OC | |
| InChIKey | ZLHFILGSQDJULK-UHFFFAOYSA-N |
- Alisertib (MLN8237) Mechanism of Action: Aurora A Kinase Inhibition in Breast Cancer Cell Research
- Alisertib (MLN8237) Clinical Trials
- Alisertib (MLN8237): Selectivity & Specificity
- Alisertib (MLN8237) Working Concentration | Cell Culture | Treatment
- Alisertib (MLN8237) Solubility in DMSO
- Alisertib (MLN8237) Stock Solution
- Alisertib (MLN8237) Storage
- Alisertib (MLN8237) Stability
- Alisertib (MLN8237) Combination Database
- Alisertib (MLN8237) SMILES
- Alisertib (MLN8237) CAS Number
- Alisertib (MLN8237) Chemical Structure (2D and 3D)
- Alisertib (MLN8237) IC50 for Cell-based and Cell-free Assays
- Alisertib (MLN8237) Sigma (AMBH2D6F735A)? Try a better option.
- Alisertib (MLN8237) MedChemExpress (HY-10971)? Try a better option.
- Alisertib (MLN8237) Cayman (13602)? Try a better option.
- Alisertib (MLN8237) Axonmedchem (Axon 2003)? Try a better option.
- Alisertib (MLN8237) APExBIO (A4110)? Try a better option.
- Alisertib (MLN8237) SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.