AG-120 (Ivosidenib) IC50 for Cell-based and Cell-free Assays

Comprehensive IC50 Values for AG-120 (Ivosidenib) Across Cell-free Enzyme Inhibitory Profiles and Cell-based Functional Assays.

AG-120 (Ivosidenib) is a potent, selective IDH1 inhibitor. It affects metabolic, epigenetic, and HR repair signaling pathways, by binding to IDH1 to reduce 2-HG levels and targeting YTHDC2, effectively inhibiting cancer cell survival and promoting cellular differentiation and apoptosis.

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