Molecular Weight: 377.43 g/mol
Chemical Structure
Check the
SB203580 (Adezmapimod)
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
38 mg/mL
(100.68 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
75 mg/mL
(198.71 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
35 mg/mL
(92.73 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
96 mg/mL
(254.35 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 28 mg/mL |
| Water | Insoluble |
| DMSO |
59 mg/mL
(156.32 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
| IUPAC Name | 4-[4-(4-fluorophenyl)-2-(4-methylsulfinylphenyl)-1H-imidazol-5-yl]pyridine | |
|---|---|---|
| CAS Number | 152121-47-6 | |
| Molecular Formula |
C21H16FN3OS |
|
| Molecular Weight (MW) | 377.43 | |
| SMILES | CS(=O)C1=CC=C(C=C1)C2=NC(=C(N2)C3=CC=NC=C3)C4=CC=C(C=C4)F | |
| InChIKey | CDMGBJANTYXAIV-UHFFFAOYSA-N |
- SB203580 (Adezmapimod) Mechanism of Action: p38 MAPK Inhibition in Tumor Cell Research
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- SB203580 (Adezmapimod) Working Concentration | Cell Culture | Treatment
- SB203580 (Adezmapimod) Solubility in DMSO
- SB203580 (Adezmapimod) Storage
- SB203580 (Adezmapimod) Stability
- SB203580 (Adezmapimod) Combination Database
- SB203580 (Adezmapimod) SMILES
- SB203580 (Adezmapimod) CAS Number
- SB203580 (Adezmapimod) Chemical Structure (2D and 3D)
- SB203580 (Adezmapimod) IC50 for Cell-based and Cell-free Assays
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- SB203580 (Adezmapimod) SDS|MSDS
Note: Technical data last updated: Sep 1, 2026.