research use only

Abaloparatide (BA058)

Cat.No.P1092

Abaloparatide (BA058, BIM-44058, ITM-058) is a novel 34-amino acid peptide selected to be a potent and selective activator of the parathyroid hormone receptor (PTH1R) signaling pathway with an IC50 of 0.117 nM in SOST analysis.

Chemical Structure

CAS No. 247062-33-5 (acetate)

Selleck's Abaloparatide (BA058) Has Been Cited by 2 Publications

Quality Control

Batch: P109201 DMSO] 80 mg/mL] false] Water] 80 mg/mL] false] Ethanol] Insoluble] false Purity: 98.04%

98.04

Featured Inhibitors	Y-27632 Dihydrochloride SB431542 CHIR-99021 (Laduviglusib) RMC-7977 RMC-6236 (Daraxonrasib) MRTX1133 MG132 Z-VAD-FMK VT3989 IAG933

Chemical Information & Solubility

Storage (From the date of receipt)	3 years-20°C powder	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
			1 month-20°Cin solvent

In vitro
Batch:

DMSO : 80 mg/mL (19.89 mM)；
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)

Water : 80 mg/mL

Ethanol : Insoluble

Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.

In vivo Formulation Calculator

Biological Activity

Description	Abaloparatide (BA058, BIM-44058, ITM-058) is a novel 34-amino acid peptide selected to be a potent and selective activator of the parathyroid hormone receptor (PTH1R) signaling pathway with an IC50 of 0.117 nM in SOST analysis.
Targets/IC₅₀/Ki	PTH1R

References
https://tspace.library.utoronto.ca/handle/1807/103220 https://pubmed.ncbi.nlm.nih.gov/27748532/

References

https://tspace.library.utoronto.ca/handle/1807/103220
https://pubmed.ncbi.nlm.nih.gov/27748532/

Product Information

Molecular Formula	C₁₇₆H₃₀₄N₅₆O₅₁
Molecular Weight	4020.709
CAS No.	247062-33-5 (acetate)
Appearance	White Powder
Peptide Content (by %N)	≥80%
Single Impurity (by HPLC)	≤1.0%
Assay (By Anhydrous, Acetic Acid-free)	95.0~105.0%
MS	Consistent
Packing	plastic vial(dedicated for peptide packing) or glass vial, quantity according to customer's detail requirement.
Storage (From the date of receipt)	3 years-20°C powder
Shipping	Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)