Numerous clinical trials spanning Early Phase 1 to Phase 4 evaluate telmisartan, primarily targeting cardiovascular conditions such as hypertension and heart failure with reduced ejection fraction accompanied by renal insufficiency. Sponsored by academic centers and commercial entities, these studies encompass diverse recruitment statuses ranging from active to completed. Beyond cardiovascular disease, research extends into oncology and neurology to assess telmisartan in indications such as prostate cancer and chemotherapy-induced neuropathic pain.
| NCT Number | Recruitment | Conditions | Sponsor/Collaborators | Start Date | Phases |
|---|---|---|---|---|---|
| NCT07207057 | RECRUITING | Parkinsons Disease (PD) |
University College, London |
2025-09-12 | PHASE3 |
| NCT07568574 | ENROLLING_BY_INVITATION | Safety and Impact of Medically Supervised Performance Enhancing Substance Usage in Healthy Elite Athletes |
Enhanced Emirates Limited |
2026-03-12 | |
| NCT07588932 | RECRUITING | Stroke |
Spaulding Rehabilitation Hospital |
2026-05-18 | EARLY_PHASE1 |
| NCT06815497 | RECRUITING | Ovarian Cancer |
Tyler J Curiel |
2026-01-21 | PHASE2 |
| NCT06168487 | RECRUITING | Prostate Cancer |
Tyler J Curiel |
2024-04-22 | PHASE1 |
| NCT07784608 | NOT_YET_RECRUITING | Drug-drug Interactions |
Huons Co., Ltd. |
2026-09 | PHASE1 |
| NCT06483789 | SUSPENDED | Panic Disorder; Mental Illness |
HB BioTech, LLC |
2024-10-29 | PHASE2 |
| NCT07370506 | NOT_YET_RECRUITING | Breast Cancer; Doxorubicin Induced Cardiomyopathy |
Tanta University |
2026-02 | PHASE1; PHASE2 |
| NCT04021550 | WITHDRAWN | Obstructive Sleep Apnea |
University of British Columbia |
2023-05 | EARLY_PHASE1 |
| NCT07652567 | COMPLETED | High-normal Blood Pressure |
Qilu Hospital of Shandong University |
2007-01-01 | |
| NCT06041529 | ACTIVE_NOT_RECRUITING | Essential Hypertension |
Yuhan Corporation |
2023-10-18 | PHASE4 |
| NCT06431477 | UNKNOWN | Diabetic Nephropathies; Hypertension |
Chong Kun Dang Pharmaceutical |
2023-04-19 | PHASE4 |
| NCT02699645 | COMPLETED | Intracerebral Haemorrhage (ICH); Hypertension |
The George Institute |
2017-09-28 | PHASE3 |
| NCT02085265 | TERMINATED | Alzheimer's Disease |
Sunnybrook Health Sciences Centre |
2014-03 | PHASE2 |
| NCT04970108 | WITHDRAWN | Hypertension Associated; Type II Diabetes Mellitus |
EMS |
2023-08 | PHASE3 |
| NCT06515652 | UNKNOWN | Metabolic Syndrome |
Hamdard University |
2023-09-01 | |
| NCT06168487 | Not yet recruiting | Prostate Cancer |
Tyler J Curiel|Dartmouth-Hitchcock Medical Center |
2024-01-01 | Early Phase 1 |
| NCT05843162 | UNKNOWN | Essential Hypertension; Metabolic Syndrome |
Chong Kun Dang Pharmaceutical |
2023-06-01 | PHASE4 |
| NCT06063109 | COMPLETED | Hypertension; Diabetes Mellitus, Type 2 |
THPharm Corp. |
2023-10-09 | PHASE1 |
| NCT04518306 | COMPLETED | Hypertension |
George Medicines PTY Limited |
2021-06-14 | PHASE3 |
| NCT03860220 | COMPLETED | Hypertension; Dyslipidemias |
Hyo-Soo Kim |
2019-04-25 | PHASE4 |
| NCT04518293 | COMPLETED | Hypertension |
George Medicines PTY Limited |
2021-07-09 | PHASE3 |
| NCT04920838 | UNKNOWN | Covid19; Covid19 Drug Treatment; Severe Acute Respiratory Syndrome Coronavirus 2; SARS-CoV2 Infection |
ANRS, Emerging Infectious Diseases |
2021-04-12 | PHASE2; PHASE3 |
| NCT05155436 | COMPLETED | Hypertension; Potassium Imbalance |
National Heart Foundation of Bangladesh |
2022-01-15 | PHASE4 |
| NCT02338232 | TERMINATED | GVHD |
Hackensack Meridian Health |
2015-07-07 | |
| NCT05322889 | COMPLETED | Neuropathic Pain; Chemotherapy Effect |
Dr. Frank Behrens |
2020-04-09 | PHASE2 |
| NCT04736329 | COMPLETED | Heart Failure With Reduced Ejection Fraction; Renal Insufficiency |
Cairo University |
2021-02-01 | |
| NCT05223101 | UNKNOWN | Hypertension |
HK inno.N Corporation |
2022-01-19 | PHASE1 |
| NCT04659070 | UNKNOWN | Primary Hypercholesterolemia; Hypertension |
Hanlim Pharm. Co., Ltd. |
2020-07-15 | PHASE3 |
| NCT02593110 | COMPLETED | Peripheral Artery Disease |
Northwestern University |
2016-01-04 | |
| NCT04360551 | TERMINATED | COVID-19 |
University of Hawaii |
2020-07-01 | PHASE2 |
| NCT04715763 | TERMINATED | Covid19 |
University of Hawaii |
2021-09-01 | PHASE2 |
| NCT04606563 | TERMINATED | Covid19; SARS-CoV Infection |
University of British Columbia |
2020-10-09 | PHASE3 |
| NCT02471833 | COMPLETED | Alzheimer's Disease |
Emory University |
2015-04 | PHASE1; PHASE2 |
| NCT04359953 | TERMINATED | COVID-19 Infection |
University Hospital, Strasbourg, France |
2020-04-25 | PHASE3 |
| NCT05223101 | Unknown status | Hypertension |
HK inno.N Corporation |
2022-01-19 | Phase 1 |
| NCT03550859 | UNKNOWN | Chronic Kidney Disease; Proteinuria |
Yuhan Corporation |
2018-06-05 | PHASE4 |
| NCT04466241 | COMPLETED | COVID-19; COVID-19 Drug Treatment; Severe Acute Respiratory Syndrome Coronavirus 2 |
ANRS, Emerging Infectious Diseases |
2020-11-27 | PHASE2; PHASE3 |
| NCT04356495 | COMPLETED | Corona Virus Infection; Sars-CoV2 |
University Hospital, Bordeaux |
2020-07-29 | PHASE2; PHASE3 |
| NCT05040880 | Completed | Hypertension |
HK inno.N Corporation |
2021-07-08 | Phase 1 |
| NCT04510662 | COMPLETED | COVID-19; Respiratory Insufficiency; Telmisartan; Respiratory Distress Syndrome, Adult |
Abraham Edgar Gracia-Ramos |
2020-08-12 | PHASE2 |
| NCT03956823 | UNKNOWN | Hypertension |
First Affiliated Hospital Xi'an Jiaotong University |
2019-08-01 | |
| NCT03783754 | TERMINATED | Stroke; Cerebral Small Vessel Diseases; Intracerebral Hemorrhage; Vascular Dementia; Hypertension |
The George Institute |
2018-08-09 | |
| NCT04218552 | COMPLETED | Hypertension,Essential |
Addpharma Inc. |
2020-02-25 | PHASE2 |
| NCT03785067 | TERMINATED | Cognitive Decline; Intracerebral Hemorrhage; Dementia, Vascular; Cerebral Small Vessel Diseases; Hypertension; Stroke Hemorrhagic |
The George Institute |
2020-02-27 | PHASE3 |
| NCT04736329 | Completed | Heart Failure With Reduced Ejection Fraction|Renal Insufficiency |
Cairo University |
2021-02-01 | Not Applicable |
| NCT04158076 | COMPLETED | Hypercholesterolemia; Hypertension |
Addpharma Inc. |
2020-01-23 | PHASE3 |
| NCT04355936 | COMPLETED | COVID-19 Drug Treatment |
Laboratorio Elea Phoenix S.A. |
2020-05-19 | PHASE4 |
| NCT03868839 | TERMINATED | Schizophrenia; Schizo Affective Disorder; Treatment-resistant Schizophrenia |
Xiaoduo Fan |
2019-02-01 | PHASE2 |
| NCT03267329 | COMPLETED | Hypertension; Dyslipidemia |
Yuhan Corporation |
2017-09-11 | PHASE4 |
| NCT03872232 | COMPLETED | Hypercholesterolemia; Hypertension |
Addpharma Inc. |
2019-02-26 | PHASE3 |
| NCT05322889 | Unknown status | Neuropathic Pain|Chemotherapy Effect |
Dr. Frank Behrens|Johann Wolfgang Goethe University Hospital|Fraunhofer Institute for Molecular Biology and Applied Ecology |
2020-04-09 | Phase 2 |
| NCT02768948 | COMPLETED | Diabetic Nephropathy |
Centre Hospitalier Universitaire de Nice |
2017-05-05 | |
| NCT03474562 | COMPLETED | ASCVD; Impaired Fasting Glucose; Hypertension |
Yuhan Corporation |
2018-04-03 | PHASE4 |
| NCT03504566 | WITHDRAWN | Diabetic Nephropathy Type 2 |
Steno Diabetes Center Copenhagen |
2017-11-15 | PHASE4 |
| NCT03707899 | COMPLETED | Hypertension With Dyslipidemia |
Jeil Pharmaceutical Co., Ltd. |
2018-12-13 | PHASE1 |
| NCT03705533 | COMPLETED | Bioequivalence |
Pharmtechnology LLC |
2018-09-07 | PHASE1 |
| NCT03662620 | COMPLETED | Hypertension |
Yuhan Corporation |
2018-10-05 | PHASE1 |
| NCT01683084 | COMPLETED | Abdominal Aortic Aneurysm |
Palo Alto Veterans Institute for Research |
2012-09-19 | PHASE4 |
| NCT02170246 | COMPLETED | Acute HIV Infection; HIV Infections |
Yale University |
2015-01-28 | PHASE1 |
| NCT03226340 | UNKNOWN | Essential Hypertension |
Seoul National University Bundang Hospital |
2015-12-02 | PHASE4 |
| NCT02231788 | COMPLETED | Hypertension |
Chong Kun Dang Pharmaceutical |
2014-06 | PHASE4 |
| NCT02968160 | TERMINATED | Metabolic Syndrome |
Yuhan Corporation |
2016-10 | PHASE4 |
| NCT02750059 | COMPLETED | Acute HIV Infection; HIV CNS Involvement |
SEARCH Research Foundation |
2015-01 | PHASE2 |
| NCT02526875 | UNKNOWN | Hypertension |
Chong Kun Dang Pharmaceutical |
2015-04 | PHASE4 |
| NCT03210532 | COMPLETED | Hypertension; Dyslipidemia |
Daewon Pharmaceutical Co., Ltd. |
2016-10-07 | PHASE3 |
| NCT03247140 | COMPLETED | Hypertension With Dyslipidemia |
Jeil Pharmaceutical Co., Ltd. |
2017-06-10 | PHASE1 |
| NCT03088254 | COMPLETED | Dyslipidemia With Hypertension |
Jeil Pharmaceutical Co., Ltd. |
2016-09-20 | PHASE3 |
| NCT03461081 | COMPLETED | Hypertension With Hyperlipidemia |
Jeil Pharmaceutical Co., Ltd. |
2017-05-07 | PHASE1 |
| NCT03566316 | COMPLETED | Hypertension With Hyperlipidemia |
IlDong Pharmaceutical Co Ltd |
2015-11-24 | PHASE3 |
| NCT03116516 | COMPLETED | Hypertension; Hyperlipidemia |
Yuhan Corporation |
2017-04-21 | PHASE1 |
| NCT03032315 | COMPLETED | Healthy |
IlDong Pharmaceutical Co Ltd |
2016-10-01 | PHASE1 |
| NCT02620163 | COMPLETED | Hypertension |
Yuhan Corporation |
2015-12 | PHASE3 |
| NCT02213224 | UNKNOWN | Nonalcoholic Fatty Liver Disease (NAFLD) |
Nanfang Hospital, Southern Medical University |
2014-08 | PHASE4 |
| NCT02951962 | COMPLETED | Hypertension; Hyperlipidemia |
Yuhan Corporation |
2016-08 | PHASE1 |
| NCT02738632 | COMPLETED | Essential Hypertension |
IlDong Pharmaceutical Co Ltd |
2015-05 | PHASE3 |
| NCT01996085 | COMPLETED | Arterial Hypertension |
Military Institute od Medicine National Research Institute |
2013-01 | |
| NCT02608242 | TERMINATED | Hypertension; Hyperlipidemia |
Yuhan Corporation |
2015-11 | PHASE1 |
| NCT01202721 | TERMINATED | Cardiac Disease |
Hamilton Health Sciences Corporation |
2011-06 | PHASE3 |
| NCT02739672 | COMPLETED | Healthy |
IlDong Pharmaceutical Co Ltd |
2016-01-02 | PHASE1 |
| NCT02079805 | COMPLETED | Essential Hypertension Complicated by Type 2 Diabetes Mellitus |
Takeda |
2014-06 | PHASE4 |
| NCT02373163 | COMPLETED | Blood Pressure, High |
Prevencion |
2014-09-01 | PHASE4 |
| NCT01928927 | COMPLETED | HIV-1 Infection |
Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections |
2014-01 | PHASE2 |
| NCT02734355 | COMPLETED | Atrial Fibrillation |
Research Institute for Complex Problems of Cardiovascular Diseases, Russia |
2015-11 | PHASE4 |
| NCT02933658 | COMPLETED | Hypertension and Dyslipidemia |
Daewon Pharmaceutical Co., Ltd. |
2015-11 | PHASE1 |
| NCT02496910 | COMPLETED | Hypertension |
Yuhan Corporation |
2015-06 | PHASE1 |
| NCT02358824 | COMPLETED | Hypertension |
Chong Kun Dang Pharmaceutical |
2015-02 | PHASE1 |
| NCT02387619 | COMPLETED | Hypertension; Hyperlipidemia |
Jeil Pharmaceutical Co., Ltd. |
2015-02 | PHASE1 |
| NCT02255253 | COMPLETED | Hypertension |
The George Institute for Global Health, China |
2014-10 | |
| NCT01075698 | COMPLETED | Hypertension |
Kumamoto University |
2009-07 | PHASE4 |
| NCT01911780 | COMPLETED | Hypertension |
Boehringer Ingelheim |
2013-07 | PHASE3 |
| NCT02057328 | UNKNOWN | Hypertension |
Aristotle University Of Thessaloniki |
2010-12 | PHASE4 |
| NCT02250833 | COMPLETED | Hypertension |
Chong Kun Dang Pharmaceutical |
2014-09 | PHASE1 |
| NCT02087540 | UNKNOWN | Hypertension; Hyperlipidemia |
IlDong Pharmaceutical Co Ltd |
2013-05 | PHASE3 |
| NCT01819220 | COMPLETED | Hypertension |
Yonsei University |
2009-04 | PHASE4 |
| NCT02233218 | COMPLETED | Healthy Male Volunteer |
Yuhan Corporation |
2014-07 | PHASE1 |
| NCT02183675 | COMPLETED | Healthy |
Boehringer Ingelheim |
2014-07 | PHASE1 |
| NCT01983735 | UNKNOWN | Hypertension |
Chong Kun Dang Pharmaceutical |
2014-01 | PHASE3 |
| NCT02129192 | COMPLETED | Healthy |
Boehringer Ingelheim |
2014-05 | PHASE1 |
| NCT02579356 | COMPLETED | Diseases of the Circulatory System; Essential Hypertension |
Samil Pharmaceutical Co., Ltd. |
2014-05 | PHASE1 |
| NCT02152969 | COMPLETED | Hypertension |
Yuhan Corporation |
2014-05 | PHASE1 |
| NCT02121535 | COMPLETED | Healthy |
Boehringer Ingelheim |
2014-04 | PHASE1 |
| NCT01975246 | COMPLETED | Hypertension |
Boehringer Ingelheim |
2013-11 | PHASE3 |
| NCT01885559 | COMPLETED | Kidney, Polycystic |
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) |
2006-01 | PHASE3 |
| NCT00283686 | COMPLETED | Kidney, Polycystic |
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) |
2006-01 | PHASE3 |
| NCT01914432 | COMPLETED | Hyperlipidemia; Hypertension |
Yuhan Corporation |
2013-11 | PHASE3 |
| NCT02047175 | COMPLETED | Hypertension; Hyperlipidemia |
Chong Kun Dang Pharmaceutical |
2014-02 | PHASE1 |
| NCT03889145 | COMPLETED | Healthy |
IlDong Pharmaceutical Co Ltd |
2013-12-19 | PHASE1 |
| NCT01748253 | UNKNOWN | Hypertension and Atrial Fibrillation |
Acrobat Trial Group |
2012-11 | |
| NCT01975961 | COMPLETED | Dyslipidemia & Hypertension |
Yuhan Corporation |
2013-07 | PHASE1 |
| NCT00863980 | TERMINATED | Acute Myocardial Infarction; Angina Pectoris; Myocardial Ischemia; Acute Coronary Syndrome; Hypertension |
Kyoto Prefectural University of Medicine |
2009-04 | |
| NCT01806363 | COMPLETED | Hypertension |
HanAll BioPharma Co., Ltd. |
2012-11 | PHASE1 |
| NCT01224860 | COMPLETED | Renal Transplant |
Mario Negri Institute for Pharmacological Research |
2009-01 | PHASE2 |
| NCT01842230 | COMPLETED | Essential Hypertension; Hyperlipidemia |
Chong Kun Dang Pharmaceutical |
2013-04 | PHASE1 |
| NCT01634295 | COMPLETED | Hypertension |
Chong Kun Dang Pharmaceutical |
2012-07 | PHASE3 |
| NCT01842256 | COMPLETED | Essential Hypertension; Hyperlipidemia |
Chong Kun Dang Pharmaceutical |
2013-04 | PHASE1 |
| NCT01578772 | COMPLETED | Endothelial Dysfunction |
University of California, Los Angeles |
2012-08 | PHASE2 |
| NCT01992601 | COMPLETED | Healthy Volunteer |
Yuhan Corporation |
2012-11 | PHASE1 |
| NCT01501253 | COMPLETED | Hypertension |
Chong Kun Dang Pharmaceutical |
2011-08 | PHASE3 |
| NCT01830530 | COMPLETED | Hypertension; High Altitude |
Istituto Auxologico Italiano |
2012-05 | PHASE4 |
| NCT01011660 | UNKNOWN | Essential Hypertension |
Chinese Academy of Medical Sciences, Fuwai Hospital |
2007-10 | PHASE4 |
| NCT00509470 | COMPLETED | Essential Hypertension |
Tokyo University |
2007-07 | PHASE4 |
| NCT01426100 | COMPLETED | Hypertension |
Chong Kun Dang Pharmaceutical |
2011-08 | PHASE3 |
| NCT00981526 | COMPLETED | Schizophrenia; Schizoaffective Disorder |
University of Massachusetts, Worcester |
2009-03 | PHASE4 |
| NCT00562952 | COMPLETED | Diabetes Mellitus; Heart Failure; Coronary Artery Disease |
Medical University of Vienna |
2007-11 | PHASE2; PHASE3 |
| NCT01180205 | UNKNOWN | Hypertension |
Johannes Gutenberg University Mainz |
2010-08 | PHASE4 |
| NCT01286558 | COMPLETED | Hypertension |
Boehringer Ingelheim |
2011-01 | PHASE3 |
| NCT01356017 | COMPLETED | Healthy Male Volunteers |
Chong Kun Dang Pharmaceutical |
2011-06 | PHASE1 |
| NCT01435161 | COMPLETED | Atrial Fibrillation |
The Second Affiliated Hospital of Chongqing Medical University |
2007-05 | PHASE4 |
| NCT01356043 | COMPLETED | Healthy Male Volunteers |
Chong Kun Dang Pharmaceutical |
2011-05 | PHASE1 |
| NCT01103960 | COMPLETED | Hypertension |
Boehringer Ingelheim |
2010-07 | PHASE3 |
| NCT01344629 | COMPLETED | Healthy |
Boehringer Ingelheim |
2011-04 | PHASE1 |
| NCT01204398 | COMPLETED | Hypertension |
Boehringer Ingelheim |
2010-11 | PHASE3 |
| NCT01222520 | COMPLETED | Hypertension |
Boehringer Ingelheim |
2010-10 | PHASE3 |
| NCT01088295 | COMPLETED | HIV Infection |
University of California, Los Angeles |
2010-05 | PHASE2 |
| NCT01134393 | COMPLETED | Hypertension |
Boehringer Ingelheim |
2010-05 | PHASE3 |
| NCT01541267 | COMPLETED | Chronic Kidney Disease; Proteinuria |
Medical University of Gdansk |
2009-12 | PHASE4 |
| NCT01128322 | COMPLETED | Hypertension |
Chong Kun Dang Pharmaceutical |
2010-07 | PHASE2 |
| NCT01278797 | COMPLETED | Hypertension |
Boehringer Ingelheim |
2011-01 | PHASE1 |
| NCT01271478 | COMPLETED | Inflammation; End-stage Renal Disease |
Coordinación de Investigación en Salud, Mexico |
2009-08 | PHASE4 |
| NCT01181011 | COMPLETED | Healthy |
Boehringer Ingelheim |
2010-08 | PHASE1 |
| NCT00865020 | COMPLETED | Hypertension |
Novartis |
2009-03 | PHASE4 |
| NCT00877929 | COMPLETED | Hypertension |
Boehringer Ingelheim |
2009-02 | PHASE3 |
| NCT00926289 | COMPLETED | Hypertension |
Boehringer Ingelheim |
2009-06 | PHASE4 |
| NCT00939588 | COMPLETED | Hypertension |
Novartis Pharmaceuticals |
2009-07 | PHASE2 |
| NCT00860262 | COMPLETED | Hypertension |
Boehringer Ingelheim |
2009-03 | PHASE3 |
| NCT00452192 | COMPLETED | Metabolic Syndrome |
University of Erlangen-Nürnberg Medical School |
2006-11 | PHASE3 |
| NCT00618774 | COMPLETED | Hypertension |
Boehringer Ingelheim |
2008-01 | PHASE3 |
| NCT00560430 | COMPLETED | Hypertension; Metabolic Syndrome; Hypertriglyceridemia |
Ludwig-Maximilians - University of Munich |
2007-11 | PHASE3 |
| NCT00750113 | COMPLETED | Hypertension |
Bayer |
2007-10 | PHASE4 |
| NCT00624052 | COMPLETED | Hypertension |
Boehringer Ingelheim |
2008-03 | PHASE3 |
| NCT00486187 | COMPLETED | Type 2 Diabetes Mellitus |
Dr. Milan Gupta |
2006-04 | |
| NCT00538486 | COMPLETED | Hypertension; Obesity |
Third Military Medical University |
2008-02 | PHASE4 |
| NCT00295542 | COMPLETED | Hypertension |
University of Vigo |
2000-03 | PHASE4 |
| NCT00614380 | COMPLETED | Hypertension |
Boehringer Ingelheim |
2008-01 | PHASE3 |
| NCT02261064 | COMPLETED | Healthy |
Boehringer Ingelheim |
2008-12 | PHASE1 |
| NCT00559286 | TERMINATED | Arterial Hypertension; Diabetes Mellitus Type 2 IRC or NIR |
RWTH Aachen University |
2007-12 | PHASE4 |
| NCT02261129 | COMPLETED | Healthy |
Boehringer Ingelheim |
2008-09 | PHASE1 |
| NCT00553267 | COMPLETED | Hypertension |
Boehringer Ingelheim |
2007-11 | PHASE3 |
| NCT02276391 | COMPLETED | Healthy |
Boehringer Ingelheim |
2008-07 | PHASE1 |
| NCT00558428 | COMPLETED | Hypertension |
Boehringer Ingelheim |
2007-10 | PHASE3 |
| NCT00558064 | COMPLETED | Hypertension |
Boehringer Ingelheim |
2007-10 | PHASE3 |
| NCT02276378 | COMPLETED | Healthy |
Boehringer Ingelheim |
2008-07 | PHASE1 |
| NCT00702936 | UNKNOWN | Acute Coronary Syndrome; Myocardial Infarction; Coronary Disease |
Catholic University of the Sacred Heart |
2007-11 | PHASE4 |
| NCT00599885 | COMPLETED | Hypertension; Diabetes; Coronary Artery Disease |
Korea University Anam Hospital |
2007-09 | PHASE4 |
| NCT00550953 | COMPLETED | Hypertension |
Boehringer Ingelheim |
2007-10 | PHASE3 |
| NCT00926341 | COMPLETED | Metabolic Syndrome |
Aligarh Muslim University |
2006-10 | PHASE4 |
| NCT00153101 | COMPLETED | Cardiovascular Diseases |
Boehringer Ingelheim |
2001-11 | PHASE4 |
| NCT00738660 | COMPLETED | Diabetic Nephropathy |
Post Graduate Institute of Medical Education and Research, Chandigarh |
2007-02 | PHASE3 |
| NCT02214966 | COMPLETED | Healthy |
Boehringer Ingelheim |
2007-10 | PHASE1 |
| NCT02193308 | COMPLETED | Healthy |
Boehringer Ingelheim |
2007-09 | PHASE1 |
| NCT02259803 | COMPLETED | Healthy |
Boehringer Ingelheim |
2007-10 | PHASE1 |
| NCT02259829 | COMPLETED | Healthy |
Boehringer Ingelheim |
2007-09 | PHASE1 |
| NCT02259777 | COMPLETED | Healthy |
Boehringer Ingelheim |
2007-09 | PHASE1 |
| NCT02242344 | COMPLETED | Hypertension |
Boehringer Ingelheim |
2006-04 | PHASE2 |
| NCT02215005 | COMPLETED | Healthy |
Boehringer Ingelheim |
2007-06 | PHASE1 |
| NCT02259790 | COMPLETED | Healthy |
Boehringer Ingelheim |
2007-07 | PHASE1 |
| NCT00326768 | COMPLETED | Hypertension |
Boehringer Ingelheim |
2006-05 | PHASE3 |
| NCT00316095 | COMPLETED | Hypertension; Dyslipidemias |
Boehringer Ingelheim |
2006-04 | PHASE3 |
| NCT00185705 | TERMINATED | Hypertension; Insulin Resistance; Dyslipidemia |
Stanford University |
2006-10 | |
| NCT02214979 | COMPLETED | Healthy |
Boehringer Ingelheim |
2007-03 | PHASE1 |
| NCT02214992 | COMPLETED | Healthy |
Boehringer Ingelheim |
2007-03 | PHASE1 |
| NCT00281593 | COMPLETED | Hypertension |
Boehringer Ingelheim |
2006-04 | PHASE3 |
| NCT02263989 | COMPLETED | Healthy |
Boehringer Ingelheim |
2007-01 | PHASE1 |
| NCT00242814 | COMPLETED | Hypertension; Metabolic Syndrome X |
Boehringer Ingelheim |
2005-11-03 | PHASE4 |
| NCT00281580 | COMPLETED | Hypertension |
Boehringer Ingelheim |
2006-04 | PHASE3 |
| NCT00267943 | COMPLETED | Hypertension |
Boehringer Ingelheim |
2006-01 | PHASE3 |
| NCT02194309 | COMPLETED | Healthy |
Boehringer Ingelheim |
2006-09 | PHASE1 |
| NCT00146341 | COMPLETED | Hypertension |
Boehringer Ingelheim |
2005-04 | PHASE3 |
| NCT00239369 | COMPLETED | Hypertension |
Boehringer Ingelheim |
2005-10 | PHASE3 |
| NCT00257491 | COMPLETED | Hypertension |
Boehringer Ingelheim |
2005-11 | PHASE3 |
| NCT02259816 | COMPLETED | Healthy |
Boehringer Ingelheim |
2006-05 | PHASE1 |
| NCT00168779 | COMPLETED | Hypertension |
Boehringer Ingelheim |
2005-09 | PHASE4 |
| NCT00168857 | COMPLETED | Hypertension; Diabetic Nephropathies |
Boehringer Ingelheim |
2003-07-09 | PHASE4 |
| NCT00147264 | COMPLETED | Metabolic Syndrome X |
McMaster University |
2004-04 | PHASE3 |
| NCT00153023 | COMPLETED | Diabetic Nephropathies; Hypertension |
Boehringer Ingelheim |
2003-04 | PHASE4 |
| NCT00153088 | COMPLETED | Diabetic Nephropathies |
Boehringer Ingelheim |
2003-01 | PHASE4 |
| NCT00146289 | COMPLETED | Obesity; Insulin Resistance |
Boehringer Ingelheim |
2005-02 | PHASE2 |
| NCT02262858 | COMPLETED | Healthy |
Boehringer Ingelheim |
2005-08 | PHASE1 |
| NCT00144222 | COMPLETED | Hypertension |
Boehringer Ingelheim |
2005-01 | PHASE3 |
| NCT00153049 | COMPLETED | Hypertension |
Boehringer Ingelheim |
2004-06 | PHASE2 |
| NCT00133185 | COMPLETED | Hypertension |
Boehringer Ingelheim |
2004-03 | PHASE3 |
| NCT02262624 | COMPLETED | Healthy |
Boehringer Ingelheim |
2005-02 | PHASE1 |
| NCT00239538 | COMPLETED | Hypertension; Diabetes Mellitus, Type 2 |
Boehringer Ingelheim |
2003-01 | PHASE4 |
| NCT00274105 | TERMINATED | Hypertension; Coronary Arteriosclerosis |
Boehringer Ingelheim |
2001-03-01 | PHASE4 |
| NCT02242812 | TERMINATED | Hypertension |
Boehringer Ingelheim |
2003-09 | PHASE4 |
| NCT02262598 | COMPLETED | Healthy |
Boehringer Ingelheim |
2004-09 | PHASE1 |
| NCT02262793 | COMPLETED | Healthy |
Boehringer Ingelheim |
2004-05 | PHASE1 |
| NCT00240448 | COMPLETED | Hypertension |
Boehringer Ingelheim |
2003-09 | PHASE4 |
| NCT02262650 | COMPLETED | Healthy |
Boehringer Ingelheim |
2004-04 | PHASE1 |
| NCT00240474 | COMPLETED | Hypertension |
Boehringer Ingelheim |
2002-12 | PHASE4 |
| NCT00274144 | COMPLETED | Hypertension; Coronary Arteriosclerosis |
Boehringer Ingelheim |
2001-12 | PHASE4 |
| NCT02262780 | COMPLETED | Healthy |
Boehringer Ingelheim |
2003-12-01 | PHASE1 |
| NCT00274118 | COMPLETED | Hypertension; Diabetes Mellitus, Type 2 |
Boehringer Ingelheim |
1997-07 | PHASE3 |
| NCT00274599 | COMPLETED | Hypertension |
Boehringer Ingelheim |
2002-10-09 | PHASE4 |
| NCT00274612 | COMPLETED | Hypertension |
Boehringer Ingelheim |
2002-10 | PHASE4 |
| NCT02262572 | COMPLETED | Healthy |
Boehringer Ingelheim |
2003-04 | PHASE1 |
| NCT00274638 | COMPLETED | Hypertension |
Boehringer Ingelheim |
2002-07 | PHASE4 |
| NCT02242318 | COMPLETED | Hypertension |
Boehringer Ingelheim |
2001-09 | PHASE4 |
| NCT00034840 | COMPLETED | Hypertension |
Boehringer Ingelheim |
2001-10 | PHASE4 |
| NCT02177461 | COMPLETED | Hypertension |
Boehringer Ingelheim |
2000-04 | PHASE4 |
| NCT02261116 | COMPLETED | Healthy |
Boehringer Ingelheim |
2002-04 | PHASE4 |
| NCT02260089 | COMPLETED | Hypertension |
Boehringer Ingelheim |
2000-03 | PHASE4 |
| NCT02178306 | COMPLETED | Hypertension |
Boehringer Ingelheim |
2000-09 | PHASE4 |
| NCT02264158 | COMPLETED | Healthy |
Boehringer Ingelheim |
2001-09 | PHASE1 |
| NCT02172586 | COMPLETED | Hypertension |
Boehringer Ingelheim |
2000-01 | PHASE4 |
| NCT02206659 | COMPLETED | Hypertension |
Boehringer Ingelheim |
2000-08 | PHASE3 |
| NCT02200653 | COMPLETED | Hypertension |
Boehringer Ingelheim |
2000-05 | PHASE4 |
| NCT02269176 | COMPLETED | Hypertension |
Boehringer Ingelheim |
2000-07 | PHASE3 |
| NCT02200640 | COMPLETED | Hypertension |
Boehringer Ingelheim |
2000-03 | PHASE4 |
| NCT02242370 | COMPLETED | Hypertension |
Boehringer Ingelheim |
1999-09 | PHASE4 |
| NCT02175355 | COMPLETED | Hypertension |
Boehringer Ingelheim |
1999-10 | PHASE3 |
| NCT02187536 | COMPLETED | Healthy |
Boehringer Ingelheim |
2000-04 | PHASE1 |
| NCT02177500 | COMPLETED | Hypertension |
Boehringer Ingelheim |
2000-01 | PHASE3 |
| NCT02177487 | COMPLETED | Hypertension |
Boehringer Ingelheim |
1999-06 | PHASE3 |
| NCT02209649 | COMPLETED | Healthy |
Boehringer Ingelheim |
1999-10 | PHASE1 |
| NCT02187523 | COMPLETED | Healthy |
Boehringer Ingelheim |
1999-10 | PHASE1 |
| NCT02177422 | COMPLETED | Hypertension |
Boehringer Ingelheim |
1998-06 | PHASE3 |
| NCT02177435 | COMPLETED | Hypertension |
Boehringer Ingelheim |
1999-02 | PHASE3 |
| NCT02176499 | COMPLETED | Hypertension |
Boehringer Ingelheim |
1999-02 | PHASE3 |
| NCT02203500 | COMPLETED | Healthy |
Boehringer Ingelheim |
1998-10 | PHASE1 |
| NCT02183701 | COMPLETED | Hypertension |
Boehringer Ingelheim |
1998-04 | PHASE3 |
| NCT02177409 | COMPLETED | Hypertension |
Boehringer Ingelheim |
1998-04 | PHASE3 |
| NCT02177396 | COMPLETED | Hypertension |
Boehringer Ingelheim |
1998-04 | PHASE3 |
| NCT02218684 | COMPLETED | Healthy |
Boehringer Ingelheim |
1998-09 | PHASE1 |
| NCT02176512 | COMPLETED | Healthy |
Boehringer Ingelheim |
1998-09 | PHASE1 |
| NCT00240422 | COMPLETED | Diabetes Mellitus, Type 2; Hypertension |
Boehringer Ingelheim |
2003-02 | PHASE4 |
| NCT00407862 | COMPLETED | Hypertension; Impaired Glucose Tolerance |
Medical University of Graz |
2005-01 | PHASE4 |
| NCT00208221 | TERMINATED | Hypertension; Type 2 Diabetes; Albuminuria |
Institut de Recherches Cliniques de Montreal |
2006-08 | PHASE3 |
| NCT00490958 | COMPLETED | Heart Failure, Congestive |
University of Campania Luigi Vanvitelli |
1999-01 | PHASE4 |
| NCT00288717 | UNKNOWN | Hypertension |
Saitama Medical University |
2006-02 |
(data from https://clinicaltrials.gov, updated on 2025-10-03)
Mechanism and Biochemical Profile
Appendix RUO and cGMP Quality Standards
| Quality Dimension | RUO (Research Use Only) | cGMP (Current Good Manufacturing Practice) |
|---|---|---|
| Clinical Applicability | Prohibited in human clinical trials or medical diagnostics. | Mandatory for human clinical trials (Phase I–III) and therapies. |
| Regulatory Status | Non-regulated grade; exempt from drug manufacturing laws. | Legally enforced by health authorities (e.g., FDA, EMA, NMPA). |
| Facility Environment | Unclassified analytical or research laboratories. | Validated Cleanrooms (ISO Class 5–8) with continuous monitoring. |
| Quality Control | Basic purity and activity testing. | Rigorous safety release testing (Sterility, Endotoxin, Mycoplasma). |
| Process Validation | Basic equipment calibration; no process validation required. | Full qualification (IQ/OQ/PQ) and complete batch records. |
| Quality Assurance | Vendor self-declared without required formal QMS. | Mandatory QA/QC unit, Change Control, CAPA, and vendor audits. |
| Regulatory Impact | High risk of IND rejection if used as a critical raw material. | Required for IND/NDA filings, supported by Drug Master Files (DMF). |
Footnotes
Regulatory Note: Governed by FDA (21 CFR Parts 210/211/312), EMA (EudraLex Vol 4), ICH Guidelines (E6/Q7/Q9/Q10), and compendial standards (USP <71>/<85>/<1043>).