Cell-free Assays (IC50/Ki) for Resveratrol (trans-Resveratrol)

Key TargetIC50 (Cell-free)DescriptionReference
mushroom tyrosinase 516.61 ±7.40 µM DOPA-chrome method Download PDF
DPPH radical 186.57 ±10.03 µM DPPH radical scavenging activity assay Download PDF
ABTS radical 20.21 ±0.37 µM ABTS radical scavenging activity assay Download PDF
α-Amylase 32.23 μM Kusano G, Takahira M, Shibano M, et al. Studies on inhibitory activities of fukiic acid esters on germination, alpha-amylase and carbo xypeptidase A. Biol Pharm Bull . 1998; 21(9): 997-999. doi: 10.1248/bpb.21.997. Download PDF
α-Glucosidase 47.93 –123 μM Zhang CC, Geng CA, Huang XY, Zhang XM, Chen JJ. Antidiabetic stilbenes from peony seeds with PTP1B, α-glucosidase, and DPPIV inhibitory activities. J Agri Food Chem . 2019; 67(24): 6765-6772. doi: 10.1021/acs.jafc.9b01193. Download PDF

Cell-based Assay (IC50) for Resveratrol (trans-Resveratrol)

Cell TypeIC50 (Cell-based)DescriptionReference
K562 single cells 97.15 μmol/L Cell viability calculated based on calcein-AM/PI staining, followed by IC50 calculation with Origin Basic Functions: Logistic dose response in Pharmaceutical/Chemistry. Download PDF
K562 cell-derived clones 90.03 μmol/L Cell viability calculated based on calcein-AM/PI staining, followed by IC50 calculation with Origin Basic Functions: Logistic dose response in Pharmaceutical/Chemistry. Download PDF
A375 cell line 256 µM (24h), 740 µM (6h) Resarzurin assay, non-linear regression with GraphPad Prism PMC12180162
W12 20861 cells 10 µM MTT assay Download PDF
W12 20822 cells 11.8 µM MTT assay Download PDF
Check the Resveratrol (trans-Resveratrol) product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

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