CAS No. 6151-25-3

Batch: Purity:98.5
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Quercetin Dihydrate Chemical Structure
Chemical Structure
Check the Quercetin Dihydrate product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxychromen-4-one;dihydrate
CAS Number 6151-25-3
Molecular Formula

C15H10O7.2H2O
Molecular Weight (MW) 338.27
SMILES C1=CC(=C(C=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O)O.O.O
InChIKey GMGIWEZSKCNYSW-UHFFFAOYSA-N

Ordering Information

Biological Activity

Quercetin Dihydrate is a natural polyphenolic flavonoid that acts as a stimulator of recombinant SIRT1 and an inhibitor of phosphatidylinositol 3-kinase (PI3K). By modulating PI3K/Akt and SIRT1 signaling pathways, it suppresses pro-inflammatory cytokine expression, reduces intracellular reactive oxygen species, and induces apoptosis in cancer cells. Additionally, Quercetin exhibits broad antioxidant and anti-inflammatory activities through downregulation of NF-kB signaling. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 67 mg/mL (198.06 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 17 mg/mL
Water Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.