2D Structure
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2D chemical structural formula diagram.
3D Structure
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This 3D model represents a theoretically simulated conformation and is for reference only.
Check the
PF-02341066 (Crizotinib)
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | 3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-(1-piperidin-4-ylpyrazol-4-yl)pyridin-2-amine | |
|---|---|---|
| CAS Number | 877399-52-5 | |
| Molecular Formula |
C21H22Cl2FN5O |
|
| Molecular Weight (MW) | 450.34 | |
| SMILES | CC(C1=C(C=CC(=C1Cl)F)Cl)OC2=C(N=CC(=C2)C3=CN(N=C3)C4CCNCC4)N | |
| InChIKey | KTEIFNKAUNYNJU-GFCCVEGCSA-N |
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
9 mg/mL
(19.98 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
45 mg/mL
(99.92 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
23 mg/mL
(51.07 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
90 mg/mL
(199.84 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
25 mg/mL
(55.51 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
- PF-02341066 (Crizotinib) Mechanism of Action: ALK Inhibition in Lung Adenocarcinoma Cell Research
- PF-02341066 (Crizotinib) Clinical Trials
- PF-02341066 (Crizotinib) Working Concentration | Cell Culture | Treatment
- PF-02341066 (Crizotinib) Solubility in DMSO
- PF-02341066 (Crizotinib) Stock Solution
- PF-02341066 (Crizotinib) Storage
- PF-02341066 (Crizotinib) Stability
- PF-02341066 (Crizotinib) Combination Database
- PF-02341066 (Crizotinib) Molecular Weight
- PF-02341066 (Crizotinib) SMILES
- PF-02341066 (Crizotinib) CAS Number
- PF-02341066 (Crizotinib) IC50 for Cell-based and Cell-free Assays
- PF-02341066 (Crizotinib) Sigma (PZ0191)? Try a better option.
- PF-02341066 (Crizotinib) MedChemExpress (HY-50878)? Try a better option.
- PF-02341066 (Crizotinib) Cayman (12087)? Try a better option.
- PF-02341066 (Crizotinib) APExBIO (A3020)? Try a better option.
- PF-02341066 (Crizotinib) SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.