CAS No. 128794-94-5

Batch: Purity:99.98
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Mycophenolate mofetil Chemical Structure
Chemical Structure
Check the Mycophenolate mofetil product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name 2-morpholin-4-ylethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1H-2-benzofuran-5-yl)-4-methylhex-4-enoate
CAS Number 128794-94-5
Molecular Formula

C23H31NO7
Molecular Weight (MW) 433.49
SMILES CC1=C2COC(=O)C2=C(C(=C1OC)CC=C(C)CCC(=O)OCCN3CCOCC3)O
InChIKey RTGDFNSFWBGLEC-SYZQJQIISA-N

Ordering Information

Biological Activity

Mycophenolate mofetil is a selective, non-competitive, and reversible inhibitor of inosine monophosphate dehydrogenase (IMPDH). As a prodrug of mycophenolic acid, it selectively suppresses the de novo pathway of purine nucleotide synthesis, which is critical for lymphocyte proliferation and activation. By depleting guanine nucleotides, it impairs downstream signal transduction, resulting in caspase-dependent apoptosis and cell cycle arrest in target cell populations.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 87 mg/mL (200.69 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water Insoluble
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.