CAS No. 71-58-9
| IUPAC Name | [(6S,8R,9S,10R,13S,14S,17R)-17-acetyl-6,10,13-trimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] acetate | |
|---|---|---|
| CAS Number | 71-58-9 | |
| Molecular Formula |
C24H34O4 |
|
| Molecular Weight (MW) | 386.52 | |
| SMILES | CC1CC2C(CCC3(C2CCC3(C(=O)C)OC(=O)C)C)C4(C1=CC(=O)CC4)C | |
| InChIKey | PSGAAPLEWMOORI-PEINSRQWSA-N |
Medroxyprogesterone acetate (MPA) is a synthetic progestin and potent progesterone receptor agonist. Upon binding to the progesterone receptor, MPA induces conformational changes that drive receptor dimerization, nuclear translocation, and transcriptional regulation of downstream target genes. This activation modulates progesterone receptor signaling pathways, leading to the regulation of cellular differentiation, inhibition of estrogen-driven cell proliferation, and control of gene expression networks in steroid-responsive tissues. [1]
|
Concentration
Volume
Mass
|
1 mg | 5 mg | 10 mg |
|---|
| Solvent | Solubility & Note |
|---|---|
| DMSO |
12 mg/mL
(31.04 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 12 mg/mL |
| Water | Insoluble |
| DMSO |
18 mg/mL
(46.56 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 15 mg/mL |
| Water | Insoluble |
| Ethanol | 15 mg/mL |
| DMSO |
7 mg/mL
(18.11 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| DMSO |
13 mg/mL
(33.63 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 11 mg/mL |
| Water | Insoluble |
| DMSO |
12 mg/mL
(31.04 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 5 mg/mL |
| Water | Insoluble |
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
- Medroxyprogesterone Acetate (MPA) Solubility in DMSO
- Medroxyprogesterone Acetate (MPA) Stock Solution
- Medroxyprogesterone Acetate (MPA) Storage
- Medroxyprogesterone Acetate (MPA) Stability
- Medroxyprogesterone Acetate (MPA) Molecular Weight
- Medroxyprogesterone Acetate (MPA) SMILES
- Medroxyprogesterone Acetate (MPA) Chemical Structure (2D and 3D)
- Medroxyprogesterone Acetate (MPA) SDS｜MSDS