Numerous clinical trials evaluate Indocyanine green across diagnostic and intraoperative applications, targeting indications such as solid tumors, breast and gastric cancers, primary and metastatic liver malignancies, and glaucoma. Spanning Early Phase 1 through Phase 4, these studies investigate molecular tumor imaging, sentinel lymph node mapping, microvascular blood flow, hepatic sufficiency, and surgical localization. Sponsored by prominent academic medical centers and health systems, including the University of Pennsylvania and St. Jude Children's Research Hospital, trial recruitment statuses range from completed studies to actively recruiting and upcoming trials.
| NCT Number | Recruitment | Conditions | Sponsor/Collaborators | Start Date | Phases |
|---|---|---|---|---|---|
| NCT07677839 | RECRUITING | Breast Cancer |
University of California, Davis |
2026-06-17 | |
| NCT07635420 | NOT_YET_RECRUITING | Head and Neck Cancer (H&N); Free Tissue Flaps; Free Flap; Free Flap Evaluation; Indocyanine Green; Indocyanine Green (ICG); Microsurgery; Randomised Controlled Trial |
Region Skane |
2026-10-01 | PHASE4 |
| NCT07060443 | RECRUITING | Right Hemicolectomy |
Pusan National University Yangsan Hospital |
2025-07-23 | PHASE2 |
| NCT06610071 | NOT_YET_RECRUITING | Dermatofibrosarcoma Protuberans (DFSP); Skin Squamous Cell Carcinoma |
The Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College |
2024-10-30 | PHASE1 |
| NCT06638125 | NOT_YET_RECRUITING | Non Small Cell Lung Cancer |
St. Joseph's Healthcare Hamilton |
2026-12-01 | PHASE1; PHASE2 |
| NCT05350540 | RECRUITING | Surgery Site Fistula |
University Health Network, Toronto |
2021-11-11 | PHASE2 |
| NCT07788001 | NOT_YET_RECRUITING | Esophageal Cancer; Sentinel Lymph Node; Lymphadenectomy; Indocyanine Green (ICG); Disease Free Survival |
Fujian Medical University Union Hospital |
2026-10-01 | PHASE3 |
| NCT06712433 | NOT_YET_RECRUITING | Sarcoma,Soft Tissue |
Adam Olson |
2026-09-30 | PHASE2 |
| NCT06421103 | RECRUITING | Perfusion; Fluorescence Imaging; Gastrointestinal Tract Disorders; Genitourinary Disease |
Great Ormond Street Hospital for Children NHS Foundation Trust |
2024-06 | |
| NCT06327490 | RECRUITING | Breast Cancer |
University of Florida |
2024-10-15 | PHASE2 |
| NCT07650656 | RECRUITING | High Grade Sarcoma; Sarcoma |
City of Hope Medical Center |
2027-05-15 | PHASE2 |
| NCT07614815 | NOT_YET_RECRUITING | Lymphedema Arm; Breast Cancer Lymphedema |
Assiut University |
2026-05-27 | |
| NCT06421220 | NOT_YET_RECRUITING | Gastric Cancer |
Qilu Hospital of Shandong University |
2024-05-20 | |
| NCT07234968 | RECRUITING | Bladder Cancer; Muscle-Invasive Bladder Carcinoma; Urothelial Carcinoma; Pelvic Malignancy; Bladder Transitional Cell Carcinoma; Bladder Neoplasm |
Thomas Jefferson University |
2025-12-23 | |
| NCT07149207 | RECRUITING | Squamous Cell Carcinoma Head and Neck Cancer (HNSCC); Margin Assessment |
Medical University of South Carolina |
2026-05-04 | PHASE2 |
| NCT04752137 | RECRUITING | Benign Neoplasm; Malignant Neoplasm |
Massachusetts General Hospital |
2022-05-25 | PHASE2 |
| NCT06583564 | ENROLLING_BY_INVITATION | Colorectal Cancer Stage III |
Shanghai Tong Ren Hospital |
2024-09-27 | |
| NCT06831149 | RECRUITING | Squamous Cell Carcinoma; Pharyngocutaneous Fistula |
Matthew Spector |
2025-02-28 | PHASE2 |
| NCT06396806 | ENROLLING_BY_INVITATION | Sigmoid Cancer |
Sun Yat-sen University |
2024-05-06 | |
| NCT07593339 | NOT_YET_RECRUITING | Epithelial Ovarian Cancer |
Başakşehir Çam & Sakura City Hospital |
2026-06-01 | |
| NCT04845828 | RECRUITING | Endometrial Cancer |
Asan Medical Center |
2022-01-26 | |
| NCT06840418 | RECRUITING | Uterine Cervical Neoplasms |
Obstetrics & Gynecology Hospital of Fudan University |
2025-01-01 | |
| NCT07638956 | NOT_YET_RECRUITING | Colon Cancer; ICG (Indocyanine Green) |
Tanta University |
2026-06-01 | |
| NCT06871787 | NOT_YET_RECRUITING | Gynecologic Cancers; Ovarian Cancer; Endometrial Cancers; Cervical Cancers; Vulvar Cancer; Anastomotic Leaks |
Istanbul University |
2025-09-01 | PHASE4 |
| NCT05344274 | RECRUITING | Glaucoma |
University of Maryland, Baltimore |
2022-05-23 | PHASE4 |
| NCT07303231 | NOT_YET_RECRUITING | Esophageal Cancer; Sentinel Lymph Node; Lymphadenectomy; Indocyanine Green |
Fujian Medical University Union Hospital |
2026-01-01 | PHASE3 |
| NCT06918210 | NOT_YET_RECRUITING | Gallstone; Gallstone; Cholecystitis, Acute |
Karolinska Institutet |
2025-08-01 | |
| NCT06002906 | ACTIVE_NOT_RECRUITING | Ulcer, Gastric; Obesity, Morbid |
University Health Network, Toronto |
2023-01-25 | PHASE4 |
| NCT07108855 | RECRUITING | Esophageal Carcinoma; Gastric Carcinoma |
University Medical Center Groningen |
2025-09-01 | PHASE1; PHASE2 |
| NCT06485609 | RECRUITING | Colon Cancer |
Sun Yat-sen University |
2024-08-10 | |
| NCT04878094 | ACTIVE_NOT_RECRUITING | Ovarian Cancer; Ovarian Carcinoma |
Memorial Sloan Kettering Cancer Center |
2021-05-03 | PHASE3 |
| NCT05369117 | NOT_YET_RECRUITING | Gastric Cancer |
Guangyong Zhang |
2022-05-31 | |
| NCT04400292 | ACTIVE_NOT_RECRUITING | Esophageal Cancer |
Memorial Sloan Kettering Cancer Center |
2020-05-20 | |
| NCT07793266 | RECRUITING | To Assess the Feasibility, Visualization Capability, and Optimal Dosing of ICG Fluorescence Imaging for Intraoperative Assessment of Knee Tissue Perfusion |
Henry Ford Health System |
2026-06-01 | PHASE1 |
| NCT07250854 | RECRUITING | Biliary Atresia; Kasai; Cholestasis in Newborn; Cholestasis in Newborn Infant |
University of Alabama at Birmingham |
2026-01-23 | EARLY_PHASE1 |
| NCT07518485 | NOT_YET_RECRUITING | N1/N2b Oral Cavity Cancer; Head and Neck Skin Cancer |
Centre Hospitalier Universitaire Vaudois |
2026-04 | PHASE2 |
| NCT05746104 | ENROLLING_BY_INVITATION | Nervous System Tumor |
Abramson Cancer Center at Penn Medicine |
2023-03-31 | PHASE1 |
| NCT05038098 | NOT_YET_RECRUITING | Gastric Adenocarcinoma |
M.D. Anderson Cancer Center |
2026-12-31 | PHASE1 |
| NCT03760575 | RECRUITING | Mesotheliomas Pleural |
Abramson Cancer Center at Penn Medicine |
2023-01-10 | PHASE1 |
| NCT04723810 | RECRUITING | Tumor, Solid |
University of Pennsylvania |
2024-08-14 | PHASE1; PHASE2 |
| NCT06198400 | RECRUITING | Pancreatic Fistula |
Charles University, Czech Republic |
2024-05-01 | |
| NCT03941756 | RECRUITING | Anatomic Stage III Breast Cancer AJCC v8; Breast Inflammatory Carcinoma; Locally Advanced Breast Carcinoma; Melanoma |
M.D. Anderson Cancer Center |
2018-08-14 | |
| NCT07481760 | NOT_YET_RECRUITING | Acute Cholecystitis; Biliary Complications |
Hospital del Mar |
2027-01-01 | |
| NCT07380867 | ENROLLING_BY_INVITATION | Colorectal Cancer; Endoscopic Tattoo of Suspected Colon Cancer; Indocyanine Green (ICG) |
Seoul St. Mary's Hospital |
2025-12-22 | |
| NCT07376876 | NOT_YET_RECRUITING | Esophageal Squamous Cell Carcinoma (ESCC); Esophageal Cancer |
Daping Hospital and the Research Institute of Surgery of the Third Military Medical University |
2026-01-01 | PHASE2 |
| NCT04719156 | RECRUITING | Sarcoma |
Kurt Weiss |
2021-03-02 | PHASE2 |
| NCT06219096 | RECRUITING | Malignant Tumor of Liver; Randomized Controlled Trial |
West China Hospital |
2023-12-10 | |
| NCT06437054 | WITHDRAWN | Hearing Loss, Sensorineural; Hearing Loss, Sudden; Intratympanic Injection |
Seoul National University Hospital |
2026-12-15 | PHASE1; PHASE2 |
| NCT06322862 | RECRUITING | Bowel; Ischemic, Acute |
Rigshospitalet, Denmark |
2024-03-05 | |
| NCT07000539 | RECRUITING | Obesity; Bariatric Surgery |
Instituto Mexicano del Seguro Social |
2025-05-06 | |
| NCT07656571 | RECRUITING | Pancreatic Neoplasms; Pancreatic Cancer |
Alexandria University |
2026-06-09 | |
| NCT07315828 | RECRUITING | Giant Cell Tumor of Bone |
Shanghai Jiao Tong University Affiliated Sixth People's Hospital |
2026-01-02 | PHASE4 |
| NCT07315841 | RECRUITING | Tenosynovial Giant Cell Tumor |
Shanghai Jiao Tong University Affiliated Sixth People's Hospital |
2026-01-02 | PHASE4 |
| NCT07400237 | RECRUITING | Cholecystectomy |
Consorci Sanitari Integral |
2025-04-01 | |
| NCT05645523 | RECRUITING | Solid Tumor |
St. Jude Children's Research Hospital |
2023-10-24 | EARLY_PHASE1 |
| NCT07682155 | RECRUITING | Anatomical Description |
Germans Trias i Pujol Hospital |
2026-02-01 | |
| NCT07195331 | RECRUITING | Laparoscopic Cholecystectomy Surgery |
Instituto de Investigación Biomédica de Salamanca |
2026-02-26 | PHASE4 |
| NCT06127836 | ACTIVE_NOT_RECRUITING | Vulvar Cancer |
Memorial Sloan Kettering Cancer Center |
2023-11-06 | |
| NCT04842162 | RECRUITING | Head and Neck Cancer |
Gustave Roussy, Cancer Campus, Grand Paris |
2020-12-15 | PHASE2 |
| NCT05646316 | RECRUITING | Stage I Uterine Corpus Carcinoma or Carcinosarcoma AJCC v8 |
NRG Oncology |
2022-12-07 | PHASE3 |
| NCT04611997 | ACTIVE_NOT_RECRUITING | Gastric Cancer; Lymph Node Metastases |
Fujian Medical University |
2020-11-16 | PHASE3 |
| NCT05937620 | RECRUITING | Ovarian Epithelial Cancer |
Fundacion Clinic per a la Recerca Biomédica |
2023-09-01 | |
| NCT02570815 | RECRUITING | Non-small Cell Lung Cancer |
St. Joseph's Healthcare Hamilton |
2016-10 | PHASE1 |
| NCT03953144 | RECRUITING | Non-small Cell Lung Cancer; Primary Neoplasm |
St. Joseph's Healthcare Hamilton |
2022-12-01 | PHASE1; PHASE2 |
| NCT07745738 | NOT_YET_RECRUITING | Pulmonary Nodule, Solitary |
Tongji Hospital |
2026-07-15 | |
| NCT07613931 | RECRUITING | Lower Extremity Lymphedema |
Tactile Medical |
2026-07-09 | EARLY_PHASE1 |
| NCT06647901 | RECRUITING | Giant Cell Tumor of Bone |
Tang Xiaodong |
2024-08-23 | PHASE1; PHASE2 |
| NCT04593615 | ACTIVE_NOT_RECRUITING | Gastric Cancer; Surgery |
Fujian Medical University |
2020-11-10 | |
| NCT06672224 | WITHDRAWN | Breast Cancer-Related Lymphedema; Breast Carcinoma |
City of Hope Medical Center |
2025-08-14 | |
| NCT04084067 | RECRUITING | Neoplastic Disease; Solid Tumor |
St. Jude Children's Research Hospital |
2020-02-07 | PHASE1 |
| NCT07513038 | RECRUITING | Biliary Atresia |
Boston Children's Hospital |
2024-08-01 | PHASE1; PHASE2 |
| NCT06845306 | NOT_YET_RECRUITING | Colo-rectal Cancer; Colonic Neoplasms Malignant |
Vadim Kuznetsov |
2025-06-01 | PHASE3 |
| NCT07406815 | NOT_YET_RECRUITING | Esophageal Cancer; Recurrent Laryngeal Nerve; ICG (Indocyanine Green); Lymph Node Dissection |
Fujian Medical University Union Hospital |
2026-06-01 | PHASE3 |
| NCT07146295 | RECRUITING | Breast Cancer; Sentinel Lymph Node Biopsy (SLNB); Sentinel Lymph Node Detection; Sentinel Lymph Node; Lymphatic Metastasis; Fluorescence Imaging; Indocyanine Green (ICG); Radioisotopes; Lymph Node Mapping |
Isabelle Henskens |
2025-04-18 | |
| NCT07316023 | RECRUITING | Stage III Periodontitis |
Nada Mahmoud Soliman |
2026-01-15 | PHASE2 |
| NCT07545278 | COMPLETED | Torsion Testis; Scrotum Disease |
Sheffield Children's NHS Foundation Trust |
2025-04-30 | PHASE4 |
| NCT06867978 | NOT_YET_RECRUITING | Frozen Sections; Indocyanine Green; Brain Tumor |
VPIX Medical |
2025-06-01 | PHASE1 |
| NCT04785443 | RECRUITING | Thyroid Diseases |
University Hospital, Brest |
2021-06-22 | PHASE3 |
| NCT07502053 | RECRUITING | Postoperative Pancreatic Fistula Post-pancreatoduodenectomy |
Institut d'Investigació Biomèdica de Girona Dr. Josep Trueta |
2024-06-15 | |
| NCT07165340 | ENROLLING_BY_INVITATION | Chronic Venous Disease |
The University of Texas Health Science Center, Houston |
2025-09 | PHASE1; PHASE2 |
| NCT05197530 | RECRUITING | Rheumatoid Arthritis |
University of Rochester |
2021-12-30 | PHASE1 |
| NCT07254845 | NOT_YET_RECRUITING | Frozen Sections; Indocyanine Green (ICG); Brain Tumor |
VPIX Medical |
2025-12-01 | PHASE1 |
| NCT06169735 | TERMINATED | Parathyroid Dysfunction; Adenoma |
University of Alabama at Birmingham |
2024-04-11 | PHASE4 |
| NCT06085274 | RECRUITING | Breast Cancer |
University Health Network, Toronto |
2025-09-03 | |
| NCT07362485 | RECRUITING | Breast Cancer; Sentinel Lymph Node Biopsy (SLNB); Sentinel Lymph Node Detection; Sentinel Lymph Node; Lymphatic Metastasis; Fluorescence Imaging; Indocyanine Green (ICG); Radioisotopes; Lymph Node Mapping; Mastectomy |
Isabelle Henskens |
2022-08-22 | |
| NCT06275022 | RECRUITING | Lymphatic Malformation |
Nanjing Children's Hospital |
2023-01-01 | |
| NCT06398028 | RECRUITING | Liver Tumor; Surgery |
Hospital Universitari Vall d'Hebron Research Institute |
2023-08-19 | PHASE4 |
| NCT05735964 | UNKNOWN | Tracheo-Esophageal Fistula with Atresia of Esophagus |
Birmingham Women's and Children's NHS Foundation Trust |
2023-03-01 | |
| NCT07144904 | NOT_YET_RECRUITING | Indocyanine Green (ICG); Robotic Surgical Procedure; Deep Infiltrating Endometriosis (DIE); Endometriosis Pelvic; Endometriosis (Diagnosis); Endometriosis of the Cul-de-sac; Ureteral Stent Placement; Ureteral Injury; Endometriosis Ovaries |
Baylor College of Medicine |
2025-10-01 | PHASE4 |
| NCT06258486 | UNKNOWN | Lymphocele; Prostate Cancer |
Kaiser Permanente |
2024-02 | PHASE4 |
| NCT06161207 | RECRUITING | Gastric Cancer; Surgery |
Fujian Medical University |
2023-01-03 | PHASE3 |
| NCT06227338 | RECRUITING | Breast Cancer |
Jules Bordet Institute |
2024-02-12 | |
| NCT06755554 | RECRUITING | Gastric Cancer Stage II; Gastric Cancer Stage III; Gastric Cancer; Gastrectomy for Gastric Cancer |
Ukrainian Society of Clinical Oncology |
2025-01-01 | PHASE3 |
| NCT06768268 | ENROLLING_BY_INVITATION | Breast Cancer Early Stage Breast Cancer (Stage 1-3) |
National Taiwan University Hospital |
2025-01-01 | PHASE1; PHASE2 |
| NCT03779009 | RECRUITING | Colon Cancer; Sentinel Lymph Node |
University Hospital, Ghent |
2018-03-01 | |
| NCT06780735 | RECRUITING | Breast Neoplasms; Breast Cancer |
National Cancer Center, Korea |
2023-07-06 | |
| NCT05808140 | COMPLETED | Disc Herniation |
Zhongnan Hospital |
2023-04-11 | PHASE1; PHASE2 |
| NCT04051502 | COMPLETED | Ovarian Cancer; Adnexal Mass |
Memorial Sloan Kettering Cancer Center |
2019-08-05 | EARLY_PHASE1 |
| NCT05960149 | UNKNOWN | Prostate Cancer Adenocarcinoma; Erectile Dysfunction Following Radical Prostatectomy |
Ankara University |
2023-07-30 | PHASE4 |
| NCT06793280 | COMPLETED | Anastomotic Leak |
University of Roma La Sapienza |
2022-02-22 | |
| NCT05830890 | UNKNOWN | Rectal Cancer Stage III; Rectal Cancer Stage IV |
National Cancer Center, China |
2023-05 | |
| NCT05709548 | UNKNOWN | Acute Cholecystitis; Bile Duct Injury |
Corporacion Parc Tauli |
2023-03-15 | PHASE4 |
| NCT05168839 | RECRUITING | Colorectal Cancer |
Centre Hospitalier Universitaire de Besancon |
2022-09-26 | PHASE3 |
| NCT06656949 | RECRUITING | Endometrial Cancer |
Qilu Hospital of Shandong University |
2024-10-30 | |
| NCT07311278 | ACTIVE_NOT_RECRUITING | Breast Cancer |
St. Antonius Hospital |
2023-06-08 | |
| NCT05087264 | UNKNOWN | Cervical Carcinoma |
Fifth Affiliated Hospital, Sun Yat-Sen University |
2022-03-10 | EARLY_PHASE1 |
| NCT04340752 | COMPLETED | Rotator Cuff Tears |
NYU Langone Health |
2021-01-27 | PHASE1 |
| NCT05507710 | UNKNOWN | Fat Necrosis |
Leiden University Medical Center |
2019-05-01 | PHASE3 |
| NCT05191212 | COMPLETED | Endometrial Cancer; Endometrial Neoplasms; Sentinel Lymph Node Biopsy (SLNB) |
Bakirkoy Dr. Sadi Konuk Research and Training Hospital |
2021-07-13 | |
| NCT06939946 | TERMINATED | Thyroid Disease; Thyroid Surgery; Parathyroid Gland |
OPTOSURGICAL, LLC |
2023-09-01 | PHASE1 |
| NCT06347354 | UNKNOWN | Breast Cancer |
Centro di Riferimento Oncologico - Aviano |
2024-09 | |
| NCT01847612 | COMPLETED | Liver Disease |
Centre Hospitalier Universitaire, Amiens |
2013-07-08 | PHASE3 |
| NCT04938973 | TERMINATED | Esophageal Cancer |
St. Joseph's Healthcare Hamilton |
2022-05-01 | |
| NCT05346380 | COMPLETED | Lung Neoplasms; Esophageal Lesion |
Massachusetts General Hospital |
2020-10-29 | PHASE1; PHASE2 |
| NCT06288750 | UNKNOWN | Total Thyroidectomy; Parathyroid Function Low Adverse Event; Parathyroid Glands--Diseases; Indocyanine Green |
Shandong Linglong Yingcheng Hospital |
2024-02-01 | |
| NCT01737619 | ACTIVE_NOT_RECRUITING | Endometrial Clear Cell Adenocarcinoma; Endometrial Mixed Adenocarcinoma; Endometrial Serous Adenocarcinoma; Grade 3 Endometrial Endometrioid Adenocarcinoma; Malignant Mixed Mesodermal (Mullerian) Tumor |
M.D. Anderson Cancer Center |
2013-04-03 | |
| NCT07551388 | COMPLETED | Acute Cholecystitis |
Peking Union Medical College Hospital |
2025-01-08 | |
| NCT05618821 | RECRUITING | Gastric Cancer |
Fujian Medical University |
2022-06-03 | PHASE2 |
| NCT06608082 | RECRUITING | Hysterectomy; Vascularization; Complication of Surgical Procedure |
University Hospital, Clermont-Ferrand |
2024-09-21 | |
| NCT07441733 | RECRUITING | Breast Cancer |
Casa di Cura Dott. Pederzoli |
2024-11-07 | |
| NCT05965817 | UNKNOWN | Colorectal Cancer; Liver Metastasis Colon Cancer; Image |
Leiden University Medical Center |
2023-12-01 | PHASE2 |
| NCT04258566 | TERMINATED | Hepatocellular Carcinoma |
National Institutes of Health Clinical Center (CC) |
2022-01-27 | |
| NCT05735977 | COMPLETED | Wilms Tumor; Renal Cancer |
Birmingham Women's and Children's NHS Foundation Trust |
2023-02-01 | |
| NCT03587532 | UNKNOWN | Anastomotic Leak; Esophageal Cancer |
University Hospital, Ghent |
2021-12-13 | |
| NCT06164392 | WITHDRAWN | Neuroma; Neuroma Amputation; Neuroma of Upper Limb; Neuroma of Lower Limb |
Northwestern University |
2024-12-28 | PHASE4 |
| NCT03751501 | COMPLETED | Macular Edema; Diabetic Retinopathy |
Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts |
2019-02-12 | |
| NCT03625765 | WITHDRAWN | Breast Reconstruction |
Case Comprehensive Cancer Center |
2019-11-22 | |
| NCT02802553 | ACTIVE_NOT_RECRUITING | Invasive Breast Cancer |
Case Comprehensive Cancer Center |
2017-12-28 | |
| NCT05376540 | UNKNOWN | Gall Stone; Cholecystitis |
Ostfold Hospital Trust |
2023-03-03 | |
| NCT05489757 | UNKNOWN | Esophagus; Fistula; Fistula;Rectal; Complication of Surgical Procedure; Complication,Postoperative |
IRCCS San Raffaele |
2022-02-16 | |
| NCT06133699 | UNKNOWN | Testicular Germ Cell Tumor |
N.N. Petrov National Medical Research Center of Oncology |
2023-11-08 | |
| NCT05453721 | COMPLETED | Segmentectomy; Non-small Cell Lung Cancer Stage I |
The First Affiliated Hospital of Nanchang University |
2022-08-04 | |
| NCT05720598 | UNKNOWN | Gastric Cancer; Lymph Node Metastasis |
Medical University of Lublin |
2022-11-04 | |
| NCT04224467 | UNKNOWN | Cervical Cancer; Ovarian Tumor; Endometrial Carcinoma; Uterine Myomatosis; Adenomyosis; Ovarian Cyst Benign; Ovarian Cyst Malignant; Endometriosis; Uterine Sarcoma |
Chen Chunlin |
2020-01-01 | |
| NCT05117853 | UNKNOWN | Thyroid Disease; Hypoparathyroidism Postprocedural |
Onze Lieve Vrouw Hospital |
2021-11-01 | PHASE3 |
| NCT04723810 | Not yet recruiting | Tumor Solid |
University of Pennsylvania |
2024-10-31 | Phase 1|Phase 2 |
| NCT05206279 | COMPLETED | Visualization of Ureters in Gynecological Surgery; Deep Infiltrative Endometriosis; ICG (Indocyanine Green); Near Infrared Imaging; Laparoscopy |
Insel Gruppe AG, University Hospital Bern |
2023-06-26 | |
| NCT05228587 | UNKNOWN | Hepatic and Hepatobiliary Disorders |
Fondazione Policlinico Universitario Agostino Gemelli IRCCS |
2022-02-01 | |
| NCT06212440 | COMPLETED | Sentinel Lymph Node Biopsy; Neoadjuvant Therapy; Breast Neoplasm |
National Cancer Center, Korea |
2021-05-04 | |
| NCT05633836 | COMPLETED | Ovarian Cancer |
Assistance Publique - Hôpitaux de Paris |
2024-03-04 | |
| NCT05734118 | UNKNOWN | NEC; Atresia; Malrotation; Intestinal Perforation |
University Medical Center Groningen |
2023-08 | |
| NCT06347354 | Not yet recruiting | Breast Cancer |
Centro di Riferimento Oncologico - Aviano |
2024-07 | Not Applicable |
| NCT06755905 | COMPLETED | Lymphatic Malformation |
Nanjing Children's Hospital |
2019-01-01 | |
| NCT07609888 | COMPLETED | Periodontitis; Chronic Periodontitis (Disorder) |
Gulf Medical University |
2023-06-01 | |
| NCT04904081 | UNKNOWN | Hirschsprung Disease; Anorectal Malformations |
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's |
2021-06-16 | PHASE3 |
| NCT05616039 | COMPLETED | Liver Cancer; Hepatocellular Carcinoma; Liver Metastasis Colon Cancer |
University Hospital Plymouth NHS Trust |
2022-11-23 | |
| NCT06579430 | COMPLETED | Hypoparathyroidism |
University Medical Center Groningen |
2020-11-05 | EARLY_PHASE1 |
| NCT06313385 | UNKNOWN | Free Flap; Indocyanine Green; Microsurgery; Temperature Change, Body |
Indonesia University |
2023-01-01 | |
| NCT05687617 | TERMINATED | Gastric Cancer; Gastric Adenocarcinoma; Peritoneal Carcinomatosis; Peritoneal Metastases |
Laval University |
2022-12-15 | PHASE2 |
| NCT05468827 | COMPLETED | Colon Cancer |
N.N. Petrov National Medical Research Center of Oncology |
2022-07-26 | |
| NCT02478138 | COMPLETED | Head and Neck Neoplasms |
University Health Network, Toronto |
2015-05 | |
| NCT05072717 | WITHDRAWN | Knee Injuries |
Dartmouth-Hitchcock Medical Center |
2022-01-12 | |
| NCT05354856 | TERMINATED | Gastric Cancer |
Rigshospitalet, Denmark |
2022-03-11 | PHASE4 |
| NCT04987281 | WITHDRAWN | Lung Non-Small Cell Carcinoma; Metastatic Malignant Neoplasm in the Lung; Stage I Lung Cancer AJCC v8 |
M.D. Anderson Cancer Center |
2022-01-26 | PHASE2 |
| NCT05926856 | COMPLETED | Extrahepatic Biliary Tree Injury |
Zhujiang Hospital |
2023-08-04 | PHASE2; PHASE3 |
| NCT04012645 | UNKNOWN | Rectal Neoplasms |
Zhongtao Zhang |
2023-11-16 | |
| NCT05125393 | UNKNOWN | Colon Cancer; Surgery |
Shanghai East Hospital |
2021-12-01 | |
| NCT05007548 | COMPLETED | Hepatic Carcinoma |
National Atomic Research Institute, Taiwan |
2021-12-14 | PHASE2 |
| NCT06173648 | COMPLETED | Pulp Necroses |
CAO Group, Inc. |
2023-08-01 | |
| NCT05130476 | COMPLETED | Hypoparathyroidism Postprocedural |
Odense University Hospital |
2021-10-01 | |
| NCT06220357 | COMPLETED | Free Flap Evaluation; Indocyanine Green Concentration; Perfusion |
Indonesia University |
2022-10-10 | |
| NCT05332405 | WITHDRAWN | Cubital Tunnel Syndrome |
NYU Langone Health |
2022-05-26 | PHASE4 |
| NCT04891185 | TERMINATED | Ovarian Cancer |
Universitaire Ziekenhuizen KU Leuven |
2021-10-01 | PHASE2 |
| NCT05645523 | Recruiting | Solid Tumor |
St. Jude Children''s Research Hospital |
2023-10-24 | Early Phase 1 |
| NCT05873621 | UNKNOWN | Rectal Cancer; Lymph Node Cancer Metastatic |
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano |
2023-01-01 | |
| NCT05946837 | COMPLETED | Neck Pain; Back Pain |
The University of Texas Health Science Center, Houston |
2023-08-29 | PHASE1 |
| NCT04374448 | UNKNOWN | Chronic Sinusitis; Tumor of Nasal Sinus; Posterior Epistaxis; Skull Base Neoplasms |
St. Paul's Sinus Centre |
2023-01-01 | |
| NCT05092750 | WITHDRAWN | Colorectal Cancer |
M.D. Anderson Cancer Center |
2021-09-15 | PHASE1; PHASE2 |
| NCT05986383 | Not yet recruiting | Primary Liver Cancer|Metastatic Liver Cancer|Benign Liver Neoplasms|Hepatic Echinococcosis |
Beijing Tsinghua Chang Gung Hospital|West China Hospital|Second Affiliated Hospital Sun Yat-Sen University|The First Hospital of Jilin University|Meng Chao Hepatobiliary Hospital of Fujian Medical University|LanZhou University|Southwest Hospital China|The Affiliated Hospital of Qingdao University|Affiliated Hospital of Qinghai University|The First Affiliated Hospital with Nanjing Medical University|Shenzhen People''s Hospital|Zhongshan Hospital Xiamen University |
2023-08 | -- |
| NCT03602677 | UNKNOWN | Colorectal Cancer; Colorectal Neoplasms; Gastrointestinal Cancer; Gastrointestinal Neoplasms; Diverticulosis, Colonic; Gastrointestinal Disease |
Oulu University Hospital |
2018-09-24 | |
| NCT04973475 | UNKNOWN | Early Gastric Cancer; Indocyanine Green; Lymph Node Dissection |
Fujian Medical University |
2021-07 | PHASE2 |
| NCT05167149 | UNKNOWN | Cervical Cancer Stage IB1 |
Cancer Institute and Hospital, Chinese Academy of Medical Sciences |
2022-02 | |
| NCT05419947 | COMPLETED | Laparoscopic Cholecystectomy |
Fundación Instituto de Estudios de Ciencias de la Salud de Castilla y León |
2022-06-20 | PHASE4 |
| NCT06629415 | COMPLETED | Chronic Calculous Cholecystitis; Laparoscopic Cholecystectomy |
Theodor Bilharz Research Institute |
2022-05-05 | PHASE4 |
| NCT05094102 | COMPLETED | Lymphedema; Surgery; Breast Cancer |
University of Wisconsin, Madison |
2022-05-05 | |
| NCT05365204 | UNKNOWN | Breast Cancer; Sentinel Lymph Node |
National Taiwan University Hospital Hsin-Chu Branch |
2022-04-08 | PHASE1 |
| NCT05365191 | UNKNOWN | Breast Cancer; Sentinel Lymph Node |
National Taiwan University Hospital Hsin-Chu Branch |
2022-04-08 | |
| NCT05229874 | UNKNOWN | Gastric Cancer |
Hebei Medical University |
2022-01-20 | PHASE2 |
| NCT03532581 | COMPLETED | Neck Dissection; Radical Lymph Node Dissection |
Ohio State University Comprehensive Cancer Center |
2018-04-23 | |
| NCT06742242 | COMPLETED | Lymphedema |
Chang Gung Memorial Hospital |
2015-09 | |
| NCT04665544 | UNKNOWN | Endometrial Cancer; Sentinel Lymph Node |
University Medical Centre Maribor |
2021-01-01 | |
| NCT05160740 | UNKNOWN | Liver Cancer |
Zhujiang Hospital |
2021-09-23 | |
| NCT05179941 | COMPLETED | Shoulder Pain; Shoulder Arthritis; Shoulder Arthroplasty |
Dartmouth-Hitchcock Medical Center |
2022-02-11 | |
| NCT04355312 | COMPLETED | Ovarian Cysts; Endometriosis; Fertility |
University Hospital, Clermont-Ferrand |
2020-06-15 | |
| NCT03927651 | COMPLETED | Fibroid Uterus; Endometriosis; Uterus Myoma; Uterine Fibroid; Uterine Adenomyosis; Endometrial Cyst; Uterine Cyst |
Northwestern University |
2019-06-01 | EARLY_PHASE1 |
| NCT05467137 | UNKNOWN | Melanoma, Stage I; Melanoma, Stage II; Melanoma Stage III |
University Medical Center Groningen |
2022-09 | PHASE4 |
| NCT07763236 | COMPLETED | Non-functioning Pituitary Adenoma |
Tomislav Felbabić |
2019-02-19 | |
| NCT02949726 | COMPLETED | Lymphedema |
The University of Texas Health Science Center, Houston |
2017-04-24 | PHASE1 |
| NCT04854018 | COMPLETED | Pediatric Renal Tumor; Metastatic Osteosarcoma; Metastatic Ewing Sarcoma; Pulmonary Metastasis; Rhabdomyosarcoma; Non-Rhabdo. Soft Tissue Sarcoma |
Birmingham Women's and Children's NHS Foundation Trust |
2021-04-30 | PHASE4 |
| NCT04615806 | UNKNOWN | Esophageal Cancer; Indocyanine Green |
Fujian Medical University Union Hospital |
2020-09-22 | |
| NCT02997553 | COMPLETED | Breast Carcinoma; Head and Neck Cancer; Melanoma (Skin); Squamous Cell Carcinoma, Skin; Cervix Cancer; Endometrium Cancer; Ovary Cancer; Vulva Cancer; Anus Cancer; Rectum Cancer |
Institut de Cancérologie de Lorraine |
2017-11-29 | PHASE3 |
| NCT04942665 | COMPLETED | Cholecystitis; Hepatocellular Carcinoma; Liver Metastases |
University of Florida |
2021-09-15 | PHASE2 |
| NCT02910726 | COMPLETED | Pediatric Patients With Solid Tumors |
Memorial Sloan Kettering Cancer Center |
2016-09-13 | PHASE2; PHASE3 |
| NCT04712032 | UNKNOWN | Colo-rectal Cancer; Crohn Disease; Resectable Colorectal Carcinoma |
Leiden University Medical Center |
2020-07-01 | PHASE3 |
| NCT02680067 | COMPLETED | Rheumatoid Arthritis |
University of Rochester |
2015-12-08 | PHASE1 |
| NCT04759820 | UNKNOWN | Number of Lymph Node Retrieved |
LI XIN-XIANG |
2021-01-01 | PHASE2; PHASE3 |
| NCT04351009 | COMPLETED | Colon Cancer |
Asian Institute of Gastroenterology, India |
2020-06-08 | |
| NCT04908826 | UNKNOWN | Laparoscopic; Cholecystectomy; Cholelithiasis; Bile Duct; Choledocholithiasis; Stone - Biliary; Post-Op Complication; Cholangiography; Indocyanine Green; Intraoperative Complications; Bile Duct Injury |
Aristotle University Of Thessaloniki |
2022-01-03 | |
| NCT04761172 | UNKNOWN | GIST |
Leiden University Medical Center |
2020-06-17 | PHASE2; PHASE3 |
| NCT05506020 | COMPLETED | Living Donor Liver Transplantation |
Fudan University |
2016-10 | |
| NCT05075889 | COMPLETED | Bone Tumor |
Dartmouth-Hitchcock Medical Center |
2021-11-11 | EARLY_PHASE1 |
| NCT04964167 | COMPLETED | Periodontitis; Periodontal Inflammation |
Riyadh Elm University |
2021-09-07 | PHASE4 |
| NCT05006950 | TERMINATED | Cholecystitis |
Stryker Endoscopy |
2021-06-28 | PHASE1 |
| NCT04591028 | WITHDRAWN | Gastric Cancer |
Mayo Clinic |
2022-01 | PHASE4 |
| NCT04624841 | UNKNOWN | Acute Cholecystitis; Acute; Cholecystitis, Choledocholithiasis; Acute Cholecystitis With Obstruction |
Hamad Medical Corporation |
2021-01-01 | PHASE4 |
| NCT03811704 | UNKNOWN | Liver Resection |
Zhujiang Hospital |
2016-01-01 | PHASE2 |
| NCT03958500 | COMPLETED | Colorectal Cancer; Colorectal Carcinoma; Colorectal Neoplasms; Colorectal Adenocarcinoma |
Vilnius University |
2019-04-01 | |
| NCT04173676 | UNKNOWN | Detection Rate of SLN ; Accuracy Rate of Lymph Node Metastasis |
Fifth Affiliated Hospital, Sun Yat-Sen University |
2019-12-02 | PHASE1 |
| NCT04882618 | UNKNOWN | Prostate Cancer; Lymph Node Metastases |
TC Erciyes University |
2019-11-08 | PHASE4 |
| NCT04107623 | COMPLETED | Stomach Neoplasms; Surgery |
Rigshospitalet, Denmark |
2020-06-16 | |
| NCT04103762 | COMPLETED | Lithiasis; Cholecystitis, Acute; Cholangiopathy |
Centre Hospitalier Universitaire, Amiens |
2019-10-01 | |
| NCT04606511 | UNKNOWN | Lymphedema |
Odense University Hospital |
2020-10-05 | |
| NCT04352894 | UNKNOWN | Peritoneal Carcinomatosis; Gastric Cancer |
Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia |
2020-09 | |
| NCT04663412 | UNKNOWN | Vulvar Cancer |
Azienda Ospedaliera per l'Emergenza Canizzaro |
2020-07-09 | |
| NCT05125653 | COMPLETED | Cholecystitis; Chronic Calculous Cholecystitis; Acute Calculous Cholecystitis |
Ain Shams University |
2020-01-01 | |
| NCT04511026 | TERMINATED | Endometrial Cancer |
Stanford University |
2021-01-20 | PHASE2 |
| NCT03745690 | WITHDRAWN | Head and Neck Carcinoma |
Jonsson Comprehensive Cancer Center |
2018-12-12 | PHASE1; PHASE2 |
| NCT04424485 | UNKNOWN | Thyroid Cancer; Thyroid Carcinoma, Papillary; Thyroid Metastases; Thyroid Neoplasms; Sentinel Lymph Node; Lymph Node Metastases |
Umraniye Education and Research Hospital |
2020-06-01 | |
| NCT04165603 | UNKNOWN | Pulmonary Nodule, Solitary; Pulmonary Nodule, Multiple |
Peking University People's Hospital |
2018-12-18 | |
| NCT04020939 | COMPLETED | Intestinal Atresia; Necrotizing Enterocolitis; Hirschsprung Disease; Gastroschisis; Intestinal Obstruction; Incarcerated Hernia; Intussusception; Malrotation; Volvulus; Meconium Ileus; Intestinal Perforation; Trauma |
St. Justine's Hospital |
2020-03-16 | |
| NCT03579199 | UNKNOWN | Liver Tumor |
Assistance Publique - Hôpitaux de Paris |
2019-03-18 | |
| NCT04833569 | COMPLETED | Peri-Implantitis |
King Saud University |
2020-09-20 | PHASE1 |
| NCT04857346 | COMPLETED | Type 2 Diabetes Mellitus; Prediabetic State; Chronic Periodontitis |
King Saud University |
2020-06-01 | PHASE2; PHASE3 |
| NCT04219332 | UNKNOWN | Indocyanine Green; Gastric Cancer; Injection Site |
Fujian Medical University |
2019-12-31 | PHASE3 |
| NCT04182152 | UNKNOWN | Lung Cancer |
Jiayuan Sun |
2019-11-05 | |
| NCT04534816 | COMPLETED | Abdominal Injuries |
Rigshospitalet, Denmark |
2020-03-12 | |
| NCT04393168 | COMPLETED | Lymphedema; Secondary Lymphedema |
Nicole Lindenblatt |
2020-05-22 | PHASE1 |
| NCT04160884 | UNKNOWN | Pulmonary Segmentectomy |
Peking University People's Hospital |
2018-12-12 | |
| NCT03854890 | UNKNOWN | Rectal Cancer |
Fudan University |
2019-07-01 | |
| NCT04046146 | COMPLETED | Rheumatoid Arthritis |
University of Rochester |
2019-12-15 | PHASE1 |
| NCT03262636 | COMPLETED | Brain Tumor, Primary; Brain Tumor, Recurrent |
University of Pennsylvania |
2015-06 | PHASE1 |
| NCT04012476 | UNKNOWN | Hypocalcemia; Total Thyroidectomy; Hypoparathyroidism Postprocedural |
Hospital Son Espases |
2016-11 | PHASE4 |
| NCT02710240 | COMPLETED | Suspected Central Nervous System Tumors |
Abramson Cancer Center at Penn Medicine |
2015-06-10 | PHASE1; PHASE2 |
| NCT03964831 | COMPLETED | Retinal Disease |
Optos, PLC |
2019-06-18 | |
| NCT03793322 | UNKNOWN | Hepatocellular Carcinoma |
Zhujiang Hospital |
2017-01-01 | PHASE1 |
| NCT03931044 | UNKNOWN | Gastric Cancer; Sentinel Lymph Node |
International Study Group on Minimally Invasive Surgery for Gastric Cancer |
2019-04 | |
| NCT03812432 | UNKNOWN | Cholecystectomy |
Hospital Son Espases |
2019-01-15 | |
| NCT03557827 | UNKNOWN | Periodontal Diseases |
National Taiwan University Hospital |
2018-03-01 | PHASE3 |
| NCT04145323 | COMPLETED | Breast Cancer; Necrosis |
University of Wisconsin, Madison |
2019-09-25 | EARLY_PHASE1 |
| NCT04266548 | COMPLETED | Hepatic Carcinoma |
Chang Gung Memorial Hospital |
2018-07-09 | |
| NCT03950206 | TERMINATED | Endometriosis |
IRCCS Azienda Ospedaliero-Universitaria di Bologna |
2019-06-01 | |
| NCT02558556 | UNKNOWN | Cholecystolithiasis; Cholecystitis |
Maastricht University Medical Center |
2016-01 | |
| NCT02462200 | TERMINATED | Breast Cancer; Cancer of Breast; Cancer of the Breast |
Washington University School of Medicine |
2016-06-13 | PHASE2 |
| NCT03969108 | COMPLETED | Thyroid Cancer; Thyroid Goiter; Graves Disease |
University Health Network, Toronto |
2019-08-06 | PHASE4 |
| NCT02111824 | TERMINATED | Lung Neoplasms; Thoracic Neoplasms; Neoplasms by Site; Neoplasms; Lung Diseases |
The Methodist Hospital Research Institute |
2014-01-05 | PHASE1 |
| NCT03850158 | COMPLETED | Endometriosis; Laparoscopy; Near Infrared Fluorescence Imaging; Indocyanine Green (ICG) |
Insel Gruppe AG, University Hospital Bern |
2017-01 | EARLY_PHASE1 |
| NCT03532074 | UNKNOWN | Endometriosis, Rectum; Bowel Endometriosis |
IRCCS Azienda Ospedaliero-Universitaria di Bologna |
2018-05-28 | |
| NCT03584633 | COMPLETED | Lymphedema |
University of Iowa |
2019-04-15 | PHASE4 |
| NCT03579979 | COMPLETED | Sentinel Lymph Node; Breast Cancer |
Chinese Academy of Sciences |
2017-08-24 | |
| NCT03430934 | COMPLETED | Skin Cancer |
University of Missouri-Columbia |
2018-07-01 | EARLY_PHASE1 |
| NCT03050879 | COMPLETED | Stomach Neoplasms; Indocyanine Green |
Fujian Medical University |
2017-10-15 | PHASE2 |
| NCT01886066 | COMPLETED | Endometrial Cancer; Sentinel Lymph Node; Indocyanine Green |
University Health Network, Toronto |
2012-03 | |
| NCT02994225 | COMPLETED | Breast Cancer |
Gustave Roussy, Cancer Campus, Grand Paris |
2017-03-10 | |
| NCT03935165 | COMPLETED | Pelvic Endometriosis; Endometriosis Outside Pelvis |
Catholic University of the Sacred Heart |
2016-01-04 | PHASE2 |
| NCT03716050 | TERMINATED | Perfusion; Complications |
Wake Forest University Health Sciences |
2018-01-30 | PHASE2; PHASE3 |
| NCT06379438 | COMPLETED | Oral Ulcer; Aphthous Recurrent Ulcers |
Yuzuncu Yil University |
2018-03-05 | |
| NCT03080558 | UNKNOWN | Deep Endometriosis; Recto Vaginal Node |
University Hospital, Clermont-Ferrand |
2017-08-06 | PHASE4 |
| NCT02419807 | COMPLETED | Stage I Breast Cancer; Stage II Breast Cancer |
Case Comprehensive Cancer Center |
2015-02-17 | |
| NCT03572998 | UNKNOWN | Secondary Lymphedema |
University of Aarhus |
2018-09 | |
| NCT02875626 | COMPLETED | Breast Cancer |
Association Pour La Recherche des Thérapeutiques Innovantes en Cancérologie |
2016-09 | |
| NCT03072186 | COMPLETED | Skull Base Neoplasms; Skull Neoplasms; Bone Neoplasm; Neoplasms; Bone Diseases; Musculoskeletal Disease |
Ohio State University |
2017-11-06 | |
| NCT03017989 | UNKNOWN | Endometriosis |
Maastricht University Medical Center |
2017-01 | |
| NCT02775838 | COMPLETED | Kidney Transplantation |
University Hospital Erlangen |
2016-04-01 | PHASE2 |
| NCT02142244 | UNKNOWN | Melanoma; Lymph Node Metastasis |
Barretos Cancer Hospital |
2014-05 | |
| NCT02840617 | UNKNOWN | Prostate Cancer |
Third Affiliated Hospital, Sun Yat-Sen University |
2016-03 | PHASE1 |
| NCT02344654 | COMPLETED | Cholecystitis; Gallstones |
Hvidovre University Hospital |
2015-05-01 | |
| NCT03292757 | COMPLETED | Chylothorax; Esophageal Cancer; Thoracic Duct Intra-Operative Injury |
Oxford University Hospitals NHS Trust |
2017-12-20 | PHASE1; PHASE2 |
| NCT03313908 | COMPLETED | Breast Cancer Female |
University Hospital, Montpellier |
2017-10-17 | |
| NCT03204994 | TERMINATED | Cancer of Rectum; Lymph Node Disease |
Oxford University Hospitals NHS Trust |
2017-08-01 | PHASE1; PHASE2 |
| NCT03204201 | TERMINATED | Urethra Injury; Rectal Cancer; Surgery |
Oxford University Hospitals NHS Trust |
2017-07-11 | PHASE1; PHASE2 |
| NCT02508298 | COMPLETED | Portal Hypertension; Cirrhosis |
VA Connecticut Healthcare System |
2014-04 | |
| NCT04056923 | COMPLETED | Pulmonary Nodule, Solitary; Lung Cancer |
Wen-zhao ZHONG |
2018-01-01 | |
| NCT02479997 | COMPLETED | Breast Cancer |
National Cancer Center, Korea |
2015-03-31 | PHASE2 |
| NCT02119858 | COMPLETED | Stage IIA Prostate Cancer; Stage IIB Prostate Cancer |
City of Hope Medical Center |
2014-08-22 | PHASE1 |
| NCT03155464 | WITHDRAWN | Systemic Sclerosis |
Duke University |
2017-06-01 | PHASE4 |
| NCT02598414 | UNKNOWN | Colon Neoplasms; Rectal Neoplasms; Inflammatory Bowel Disease; Diverticular Disease |
Acibadem University |
2015-11 | PHASE2; PHASE3 |
| NCT02415725 | UNKNOWN | Lymphadenectomy; Breast Cancer |
Centre Hospitalier Universitaire Saint Pierre |
2014-09 | |
| NCT02851368 | COMPLETED | Solitary Pulmonary Nodules |
University of Pittsburgh |
2016-11 | EARLY_PHASE1 |
| NCT01281488 | COMPLETED | Recurrent Renal Cell Cancer; Stage I Renal Cell Cancer; Stage II Renal Cell Cancer |
City of Hope Medical Center |
2011-10-20 | PHASE1 |
| NCT02570958 | WITHDRAWN | Non-small Cell Lung Cancer; Thoracic Surgery |
St. Joseph's Healthcare Hamilton |
2017-10 | PHASE1 |
| NCT01034670 | TERMINATED | Gastrointestinal Diseases; Gastric (Stomach) Cancer; Gastrointestinal Stromal Tumor (GIST) |
Stanford University |
2009-06 | |
| NCT02920216 | COMPLETED | Head and Neck Cancer |
Institut de Cancérologie de Lorraine |
2016-12-06 | |
| NCT02822833 | UNKNOWN | Endometrial Neoplasm |
Ankara University |
2016-07 | |
| NCT02669485 | UNKNOWN | Anastomotic Leak |
The University of Hong Kong |
2016-01 | |
| NCT03129763 | COMPLETED | Tissue Expander Disorder |
Shanghai Jiao Tong University School of Medicine |
2017-01-07 | |
| NCT02759796 | COMPLETED | Breast Cancer; Vascularization; Fat Necrosis |
Instituto de Investigación Hospital Universitario La Paz |
2015-11 | |
| NCT02564276 | COMPLETED | Endometrial Neoplasms |
Centre hospitalier de l'Université de Montréal (CHUM) |
2016-02 | PHASE3 |
| NCT02131558 | COMPLETED | Endometrial Cancer; Sentinel Lymph Node Detection |
Lahey Clinic |
2014-05 | |
| NCT03332004 | COMPLETED | Pelvic Endometriosis; Endometriosis Outside Pelvis |
Catholic University of the Sacred Heart |
2016-01-04 | PHASE2 |
| NCT02781259 | UNKNOWN | Breast Neoplasms |
Samsung Medical Center |
2016-05 | PHASE4 |
| NCT02280954 | COMPLETED | Solid Tumor; Neoplasms |
University of Pennsylvania |
2013-11 | PHASE1 |
| NCT01419860 | COMPLETED | Colon Cancer; Benign Colon Diseases |
Ostfold Hospital Trust |
2010-01 | |
| NCT01818739 | COMPLETED | Endometrial Cancer |
Ohio State University Comprehensive Cancer Center |
2013-03 | |
| NCT01796041 | COMPLETED | Invasive Ductal Carcinoma; Invasive Lobular Carcinoma; Ductal Carcinoma |
Abramson Cancer Center at Penn Medicine |
2011-07 | EARLY_PHASE1 |
| NCT02423148 | WITHDRAWN | Lung Cancer |
Dana-Farber Cancer Institute |
2015-05 | |
| NCT02621268 | COMPLETED | Neoplasms |
University of Pennsylvania |
2014-11 | PHASE1 |
| NCT03097627 | COMPLETED | Pulmonary Nodule, Solitary; Pulmonary Nodule, Multiple |
Brigham and Women's Hospital |
2016-02-01 | PHASE1; PHASE2 |
| NCT02611245 | COMPLETED | Lung Cancer; Esophageal Cancer |
Chinese Academy of Sciences |
2015-08 | PHASE1 |
| NCT01939028 | TERMINATED | Stage I Endometrial Carcinoma; Stage II Endometrial Carcinoma; Stage III Endometrial Carcinoma; Stage IV Endometrial Carcinoma |
Case Comprehensive Cancer Center |
2013-07 | |
| NCT02817334 | UNKNOWN | Breast Cancer |
National Cancer Center, Korea |
2016-03 | PHASE2 |
| NCT01424293 | COMPLETED | Rectal Neoplasms; Colon Neoplasms; Diverticulitis |
Maimonides Medical Center |
2010-05 | |
| NCT03012750 | COMPLETED | Peripheral Arterial Disease |
University Hospital Erlangen |
2015-02 | PHASE2 |
| NCT02279108 | COMPLETED | Breast Neoplasms |
Centre Hospitalier Universitaire de Saint Etienne |
2014-11 | PHASE3 |
| NCT02552901 | WITHDRAWN | Hepatic Failure; Liver Failure |
Cardiox Corporation |
2015-11 | PHASE3 |
| NCT01969448 | COMPLETED | Ductal Carcinoma in Situ - Category; Breast Cancer; Prophylactic Mastectomy |
Washington University School of Medicine |
2013-03-28 | |
| NCT02260349 | WITHDRAWN | Prostatic Neoplasms |
Centre Hospitalier Universitaire de Saint Etienne |
2014-04 | PHASE3 |
| NCT02167087 | COMPLETED | Colon Cancer; Lymphatic Metastasis |
Ismail Gögenür |
2015-03 | |
| NCT02249780 | COMPLETED | Parathyroid Function Low Adverse Event |
University Hospital, Geneva |
2014-09 | |
| NCT02850783 | COMPLETED | Sentinel Lymph Node |
VU University of Amsterdam |
2015-03 | PHASE2; PHASE3 |
| NCT01873716 | COMPLETED | Atherosclerosis; Atherosclerotic Plaque; Carotid Stenosis |
Massachusetts General Hospital |
2013-05 | PHASE1 |
| NCT02057393 | COMPLETED | Melanoma; Sentinel Node |
Milton S. Hershey Medical Center |
2014-06 | |
| NCT02473159 | UNKNOWN | Breast Cancer |
National Cancer Center, Korea |
2015-03 | PHASE2 |
| NCT01836848 | UNKNOWN | Subarachnoid Hemorrhage, Aneurysmal; Intracerebral Hemorrhage (ICH); Traumatic Brain Injury |
University of Cologne |
2013-06 | |
| NCT02405559 | UNKNOWN | Lymphatic Function |
Centre Hospitalier Universitaire Saint Pierre |
2015-05 | EARLY_PHASE1 |
| NCT02117310 | COMPLETED | Skull Base Neoplasms |
Ohio State University |
2015-03 | |
| NCT01662752 | COMPLETED | Colorectal Cancer |
Imperial College London |
2013-05 | PHASE2 |
| NCT02084784 | COMPLETED | Sentinel Lymph Node; Breast Cancer |
Chinese Academy of Sciences |
2014-01 | |
| NCT00757471 | COMPLETED | Idiopathic Macular Holes |
The Ludwig Boltzmann Institute of Retinology and Biomicroscopic Laser Surgery |
2008-08 | |
| NCT02368067 | UNKNOWN | Endometrial Carcinoma |
Southeastern Regional Medical Center |
2014-06 | |
| NCT01974622 | UNKNOWN | Retinal Vascular Disorders |
Manhattan Eye, Ear & Throat Hospital |
2013-04 | |
| NCT02163083 | COMPLETED | Prostate Cancer |
St. Antonius Hospital Gronau |
2014-08 | |
| NCT01771666 | COMPLETED | Breast Cancer |
Stanford University |
2012-07 | PHASE2 |
| NCT01693484 | TERMINATED | Fractures, Comminuted; Surgical Wound Dehiscence; Necrosis |
Louisiana State University Health Sciences Center Shreveport |
2013-04 | PHASE2; PHASE3 |
| NCT01884584 | COMPLETED | Malignant Neoplasm |
Emory University |
2012-06 | PHASE1 |
| NCT01554267 | UNKNOWN | Breast Cancer; Breast Reconstruction; Mastectomy |
Stony Brook University |
2014-01 | |
| NCT02068820 | COMPLETED | Endometrial Cancer |
AdventHealth |
2012-09 | |
| NCT01335893 | COMPLETED | Lung Neoplasms |
University of Pennsylvania |
2011-05 | PHASE1 |
| NCT02359578 | COMPLETED | Determination of the Occlusion Pressure in Lymphatic Vessels |
Centre Hospitalier Universitaire Saint Pierre |
2014-08 | EARLY_PHASE1 |
| NCT02032563 | UNKNOWN | Breast Cancer |
Jules Bordet Institute |
2013-12 | PHASE2 |
| NCT01295931 | COMPLETED | Melanoma |
M.D. Anderson Cancer Center |
2011-02 | PHASE1 |
| NCT01834469 | COMPLETED | Ovarian Cancer; Peritoneal Carcinomatosis |
Jules Bordet Institute |
2013-03 | PHASE1; PHASE2 |
| NCT02027818 | COMPLETED | Breast Cancer |
Jules Bordet Institute |
2014-01 | PHASE2 |
| NCT02027831 | UNKNOWN | Head and Neck Cancer |
Jules Bordet Institute |
2013-12 | PHASE2 |
| NCT02032498 | UNKNOWN | Breast Cancer |
Jules Bordet Institute |
2013-07 | PHASE2 |
| NCT02032485 | COMPLETED | Colorectal Cancer; Peritoneal Carcinomatosis |
Jules Bordet Institute |
2013-03 | PHASE2 |
| NCT01993576 | COMPLETED | Breast Cancer. |
Jules Bordet Institute |
2013-01 | PHASE1; PHASE2 |
| NCT02070627 | COMPLETED | Acute Cholecystitis; Acute Cholangitis |
Ohio State University |
2013-07 | PHASE1 |
| NCT01424215 | COMPLETED | Cholelithiasis; Cholecystitis; Pancreatitis Biliary; Colic of Gallbladder Without Mention of Cholecystitis |
Maimonides Medical Center |
2011-01 | |
| NCT02070640 | COMPLETED | Cholecystitis |
Ohio State University |
2013-01 | |
| NCT02766244 | COMPLETED | Burns |
Texas Tech University Health Sciences Center |
2014-01 | |
| NCT01898403 | COMPLETED | Recurrent Melanoma |
Stanford University |
2013-06 | |
| NCT01962649 | COMPLETED | Hepatocellular Carcinoma |
Massachusetts General Hospital |
2013-10 | EARLY_PHASE1 |
| NCT01801306 | COMPLETED | Spontaneous Subarachnoid Hemorrhage |
NeMoDevices AG |
2013-03 | |
| NCT01095913 | COMPLETED | Breast Cancer |
M.D. Anderson Cancer Center |
2010-03 | PHASE1 |
| NCT02043340 | COMPLETED | Periodontitis |
SVS Institute of Dental Sciences |
2012-10 | PHASE2 |
| NCT01410734 | COMPLETED | Gallbladder Disease; Biliary Colic; Gallstones |
Intuitive Surgical |
2011-07 | |
| NCT01856452 | COMPLETED | Breast Neoplasms |
National Cancer Center, Korea |
2011-09 | PHASE2 |
| NCT01276054 | TERMINATED | Lymphedema; Recurrent Breast Cancer; Stage IA Breast Cancer; Stage IB Breast Cancer; Stage II Breast Cancer |
University of Southern California |
2010-12 | PHASE2 |
| NCT01083004 | UNKNOWN | Macular Pucker; Macular Hole; Vitreoretinal Surgery |
University of Cologne |
2008-01 | PHASE3 |
| NCT01204554 | UNKNOWN | Reconstructive Surgery; Microcirculation |
Oslo University Hospital |
2008-09 | EARLY_PHASE1 |
| NCT01112514 | COMPLETED | High Risk Polyposis Syndrome; Distal Colonic Lesions; Colorectal Polyps |
Massachusetts General Hospital |
2010-02 | |
| NCT00540982 | COMPLETED | Lung Cancer; Unspecified Adult Solid Tumor, Protocol Specific |
City of Hope Medical Center |
1997-02-20 | PHASE1; PHASE2 |
| NCT00187421 | COMPLETED | Coronary Disease |
Sunnybrook Health Sciences Centre |
2005-07 | PHASE3 |
| NCT00674323 | COMPLETED | Polypoidal Choroidal Vasculopathy |
Novartis |
2008-04 | PHASE4 |
| NCT00453050 | COMPLETED | Melanoma (Skin); Metastatic Cancer |
University of Oklahoma |
2006-03 | PHASE1 |
| NCT00137254 | COMPLETED | Burns |
United States Army Institute of Surgical Research |
2005-12 | |
| NCT00419185 | COMPLETED | Idiopathic Macular Hole |
University of Luebeck |
2003-04 | |
| NCT00484913 | COMPLETED | Healthy |
University Hospital Freiburg |
2003-09 | PHASE1 |
| NCT00383825 | COMPLETED | Pterygium |
Baskent University |
2003-01 | |
| NCT00376857 | COMPLETED | Idiopathic Epiretinal Membrane, Cataract |
University of Regensburg |
||
| NCT00331253 | UNKNOWN | Maculopathy, Age-Related |
Opto Eletronica S.A. |
2007-04 | PHASE2 |
(data from https://clinicaltrials.gov, updated on 2026-07-01)
Mechanism and Biochemical Profile
Appendix RUO and cGMP Quality Standards
| Quality Dimension | RUO (Research Use Only) | cGMP (Current Good Manufacturing Practice) |
|---|---|---|
| Clinical Applicability | Prohibited in human clinical trials or medical diagnostics. | Mandatory for human clinical trials (Phase I–III) and therapies. |
| Regulatory Status | Non-regulated grade; exempt from drug manufacturing laws. | Legally enforced by health authorities (e.g., FDA, EMA, NMPA). |
| Facility Environment | Unclassified analytical or research laboratories. | Validated Cleanrooms (ISO Class 5–8) with continuous monitoring. |
| Quality Control | Basic purity and activity testing. | Rigorous safety release testing (Sterility, Endotoxin, Mycoplasma). |
| Process Validation | Basic equipment calibration; no process validation required. | Full qualification (IQ/OQ/PQ) and complete batch records. |
| Quality Assurance | Vendor self-declared without required formal QMS. | Mandatory QA/QC unit, Change Control, CAPA, and vendor audits. |
| Regulatory Impact | High risk of IND rejection if used as a critical raw material. | Required for IND/NDA filings, supported by Drug Master Files (DMF). |
Footnotes
Regulatory Note: Governed by FDA (21 CFR Parts 210/211/312), EMA (EudraLex Vol 4), ICH Guidelines (E6/Q7/Q9/Q10), and compendial standards (USP <71>/<85>/<1043>).