Ifosfamide has been evaluated across numerous clinical trials ranging from Early Phase 1 through Phase 4 for the treatment of diverse malignancies, including leiomyosarcoma, osteosarcoma, small cell lung cancer, and non-Hodgkin lymphomas. Supported by academic medical centers, government institutions, and pharmaceutical sponsors, these investigations encompass completed, recruiting, and terminated protocols. Overall, this body of research underscores ifosfamide as a core component of combination chemotherapy regimens for relapsed, refractory, or advanced solid tumors and hematologic cancers.
| NCT Number | Recruitment | Conditions | Sponsor/Collaborators | Start Date | Phases |
|---|---|---|---|---|---|
| NCT06239272 | RECRUITING | Adipocytic Neoplasm; Liposarcoma; Atypical Fibroxanthoma; Angiomatoid Fibrous Histiocytoma; Fibrosarcoma NOS; Myxofibrosarcoma; Angiosarcoma; Osteosarcoma, Extraskeletal; Dedifferentiated Liposarcoma; Myxoid Liposarcoma; Pleomorphic Liposarcoma; Myxoid Pleomorphic Liposarcoma; Low Grade Fibromyxoid Sarcoma; Sclerosing Epithelioid Fibrosarcoma; Malignant Tenosynovial Giant Cell Tumor of Soft Tissue; Epithelioid Hemangioendothelioma; Glomus Tumor; Inflammatory Leiomyosarcoma; Leiomyosarcoma; Ossifying Fibromyxoid Tumor, Malignant; Myoepithelioma; Synovial Sarcoma; Epithelioid Sarcoma; Perineurioma, Malignant; Clear Cell Sarcoma; Extraskeletal Myxoid Chondrosarcoma; Granular Cell Tumor, Malignant; Melanotic Malignant Nerve Sheath Tumor; Malignant Peripheral Nerve Sheath Tumor; Perivascular Epithelioid Tumor, Malignant; Intimal Sarcoma; Myoepithelial Carcinoma; Undifferentiated Sarcoma; Pleomorphic Sarcoma, Undifferentiated; Round Cell Sarcoma, Undifferentiated; NTRK-Rearranged Spindle Cell Neoplasm; Phosphaturic Mesenchymal Tumor, Malignant; Round Cell Sarcoma; Well Differentiated Liposarcoma; Giant Cell Tumor of Soft Parts NOS; Low Grade Myofibroblastic Sarcoma; Dermatofibrosarcoma Protuberans, Fibrosarcomatous |
St. Jude Children's Research Hospital |
2024-03-27 | PHASE1; PHASE2 |
| NCT02106988 | ACTIVE_NOT_RECRUITING | Lymphoma |
M.D. Anderson Cancer Center |
2015-01-16 | PHASE2 |
| NCT07724457 | NOT_YET_RECRUITING | Recurrent Burkitt Lymphoma; Recurrent High Grade B-Cell Lymphoma With MYC and BCL2 Rearrangements; Refractory Burkitt Lymphoma; Refractory High Grade B-Cell Lymphoma With MYC and BCL2 Rearrangements |
National Cancer Institute (NCI) |
2026-10-30 | PHASE2; PHASE3 |
| NCT07321912 | RECRUITING | Osteosarcoma; Ewing Sarcoma |
Milton S. Hershey Medical Center |
2026-06-05 | PHASE2 |
| NCT02375204 | ACTIVE_NOT_RECRUITING | Germ Cell Tumor; Teratoma; Choriocarcinoma; Germinoma; Mixed Germ Cell Tumor; Yolk Sac Tumor; Childhood Teratoma; Malignant Germ Cell Neoplasm; Extragonadal Seminoma; Non-seminomatous Germ Cell Tumor; Seminoma |
Alliance for Clinical Trials in Oncology |
2015-08-06 | PHASE3 |
| NCT05991388 | RECRUITING | B-cell Non Hodgkin Lymphoma |
University of Birmingham |
2024-05-02 | PHASE2; PHASE3 |
| NCT03418038 | RECRUITING | Clonal Cytopenia of Undetermined Significance; High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements; Recurrent Diffuse Large B-Cell Lymphoma; Recurrent Hodgkin Lymphoma; Recurrent Lymphoma; Refractory Diffuse Large B-Cell Lymphoma; Refractory Lymphoma; Chronic Myelomonocytic Leukemia |
Mayo Clinic |
2018-03-23 | PHASE2 |
| NCT07194044 | RECRUITING | Metastatic Ewing Sarcoma |
H. Lee Moffitt Cancer Center and Research Institute |
2026-02-05 | PHASE1 |
| NCT04625907 | RECRUITING | Rhabdomyosarcoma |
University of Birmingham |
2020-09-17 | PHASE1; PHASE2 |
| NCT04043494 | RECRUITING | Lymphoblastic Lymphoma, Childhood |
University Hospital Muenster |
2019-08-23 | PHASE3 |
| NCT04684368 | RECRUITING | Central Nervous System Nongerminomatous Germ Cell Tumor; Choriocarcinoma; Embryonal Carcinoma; Immature Teratoma; Malignant Teratoma; Mixed Germ Cell Tumor; Pineal Region Germ Cell Tumor; Pineal Region Immature Teratoma; Pineal Region Yolk Sac Tumor; Suprasellar Germ Cell Tumor |
Children's Oncology Group |
2021-07-13 | PHASE2 |
| NCT05533775 | RECRUITING | Mature B-Cell Non-Hodgkin Lymphoma |
Hoffmann-La Roche |
2022-11-16 | PHASE1; PHASE2 |
| NCT06528496 | RECRUITING | High-risk Neuroblastoma; Neuroblastoma; Childhood Neuroblastoma |
Memorial Sloan Kettering Cancer Center |
2024-07-22 | PHASE2 |
| NCT06647953 | RECRUITING | Pleuropulmonary Blastoma |
Children's Oncology Group |
2025-03-21 | PHASE3 |
| NCT06792253 | RECRUITING | Relapsed/Refractory Diffuse Large B-Cell Lymphoma |
BeBetter Med Inc |
2025-01-06 | PHASE3 |
| NCT04199026 | RECRUITING | Metastatic Sarcoma; Recurrent Sarcoma; Resectable Sarcoma |
M.D. Anderson Cancer Center |
2025-02-25 | |
| NCT06552559 | RECRUITING | B-cell Lymphoma Recurrent; B-cell Lymphoma Refractory; CNS Metastases |
Samsung Medical Center |
2024-05-01 | PHASE1; PHASE2 |
| NCT03643276 | RECRUITING | Acute Lymphoblastic Leukemia, Pediatric |
Martin Schrappe |
2018-07-15 | PHASE3 |
| NCT06905509 | RECRUITING | Recurrent Diffuse Large B-Cell Lymphoma; Recurrent Diffuse Large B-Cell Lymphoma, Not Otherwise Specified; Recurrent High Grade B-Cell Lymphoma With MYC and BCL2 Rearrangements; Recurrent High Grade B-Cell Lymphoma With MYC and BCL6 Rearrangements; Recurrent High Grade B-Cell Lymphoma, Not Otherwise Specified; Recurrent Nodal Marginal Zone Lymphoma; Recurrent Transformed Follicular Lymphoma to Diffuse Large B-Cell Lymphoma; Refractory Diffuse Large B-Cell Lymphoma; Refractory Diffuse Large B-Cell Lymphoma, Not Otherwise Specified; Refractory High Grade B-Cell Lymphoma With MYC and BCL2 Rearrangements; Refractory High Grade B-Cell Lymphoma With MYC and BCL6 Rearrangements; Refractory High Grade B-Cell Lymphoma, Not Otherwise Specified; Refractory Nodal Marginal Zone Lymphoma; Refractory Transformed Follicular Lymphoma to Diffuse Large B-Cell Lymphoma |
University of California, Davis |
2025-07-31 | PHASE2 |
| NCT06204614 | ENROLLING_BY_INVITATION | Muscle Invasive Bladder Urothelial Carcinoma |
Brigham and Women's Hospital |
2024-06-14 | EARLY_PHASE1 |
| NCT05711628 | WITHDRAWN | Recurrent Classic Hodgkin Lymphoma; Refractory Classic Hodgkin Lymphoma |
National Cancer Institute (NCI) |
2023-08-10 | PHASE3 |
| NCT06230224 | ACTIVE_NOT_RECRUITING | B-Cell Non-Hodgkin Lymphoma (B-NHL) |
Regeneron Pharmaceuticals |
2024-02-15 | PHASE3 |
| NCT06835049 | RECRUITING | Sarcoma,Soft Tissue |
Swiss Cancer Institute |
2025-10-27 | PHASE2 |
| NCT07477457 | RECRUITING | Osteosarcoma; Metastasis |
Memorial Sloan Kettering Cancer Center |
2026-03-11 | PHASE2 |
| NCT06849986 | RECRUITING | Soft Tissue Sarcomas; Angiosarcoma; Fibrosarcoma; Leiomyosarcoma; Pleomorphic Liposarcoma; Malignant Peripheral Nerve Sheath Tumor (MPNST); Desmoplastic Small Round Cell Tumor |
Fudan University |
2025-02-25 | PHASE2 |
| NCT03719105 | RECRUITING | NK-Cell Lymphoma; NK-Cell Leukemia; Peripheral T Cell Lymphoma |
New York Medical College |
2019-03-01 | EARLY_PHASE1 |
| NCT06156410 | RECRUITING | Ewing Sarcoma; Osteosarcoma; Sarcomas |
Children's Hospital of Philadelphia |
2023-10-24 | PHASE1 |
| NCT07389356 | NOT_YET_RECRUITING | DLBCL - Diffuse Large B Cell Lymphoma |
The First Affiliated Hospital with Nanjing Medical University |
2026-02-25 | |
| NCT00077285 | ACTIVE_NOT_RECRUITING | Sarcoma |
Memorial Sloan Kettering Cancer Center |
2003-10 | PHASE2 |
| NCT04663347 | ACTIVE_NOT_RECRUITING | Diffuse Large B-Cell Lymphoma; Follicular Lymphoma |
Genmab |
2020-11-03 | PHASE1; PHASE2 |
| NCT04322318 | RECRUITING | Anaplastic Kidney Wilms Tumor; Recurrent Kidney Wilms Tumor; Stage II Kidney Wilms Tumor; Stage III Kidney Wilms Tumor; Stage IV Kidney Wilms Tumor |
Children's Oncology Group |
2020-10-19 | PHASE2 |
| NCT04947501 | ACTIVE_NOT_RECRUITING | Neuroblastoma; Pediatric Cancer |
Memorial Sloan Kettering Cancer Center |
2021-06-22 | EARLY_PHASE1 |
| NCT06415318 | RECRUITING | Penile Cancer |
Sun Yat-sen University |
2024-05-31 | PHASE2 |
| NCT03206671 | ACTIVE_NOT_RECRUITING | Mature B-cell Non-Hodgkin Lymphoma |
University Hospital Muenster |
2017-08-03 | PHASE3 |
| NCT01873326 | ACTIVE_NOT_RECRUITING | Germ Cell Tumors |
Memorial Sloan Kettering Cancer Center |
2013-06 | PHASE2 |
| NCT06451302 | ACTIVE_NOT_RECRUITING | Ewing Sarcoma; Risk Stratification |
Yizhuo Zhang |
2024-04-17 | |
| NCT02305654 | ACTIVE_NOT_RECRUITING | Squamous Cell Carcinoma of the Penis, Usual Type |
Institute of Cancer Research, United Kingdom |
2017-05-12 | PHASE3 |
| NCT01864109 | ACTIVE_NOT_RECRUITING | Newly Diagnosed Ewing Sarcoma |
Memorial Sloan Kettering Cancer Center |
2013-05 | PHASE2 |
| NCT07081022 | ACTIVE_NOT_RECRUITING | B-cell Non-Hodgkin's Lymphoma |
Shanghai Junshi Bioscience Co., Ltd. |
2025-08-17 | PHASE2 |
| NCT06839703 | NOT_YET_RECRUITING | High-risk GD2-Positive Ewing Sarcoma |
Prof. Dr. Dirk Reinhardt |
2025-03-01 | PHASE1 |
| NCT05681260 | RECRUITING | T-cell Lymphoblastic Lymphoma |
Children's Cancer Group, China |
2023-02-06 | PHASE3 |
| NCT06489808 | RECRUITING | Relapsed/Refractory Large B-Cell Lymphoma |
Institute of Hematology & Blood Diseases Hospital, China |
2024-05-28 | PHASE2 |
| NCT07243626 | RECRUITING | Soft Tissue Sarcoma |
Second Affiliated Hospital, Zhejiang University, School of Medicine |
2024-09-30 | PHASE2 |
| NCT06684327 | RECRUITING | Paget Disease, Extramammary; Rhabdomyosarcoma; Testicular Cancer; Penile Cancer; Urachal Cancer |
Fudan University |
2024-11-30 | PHASE2 |
| NCT05590572 | NOT_YET_RECRUITING | Osteosarcoma |
Second Affiliated Hospital, Zhejiang University, School of Medicine |
2023-01 | PHASE1; PHASE2 |
| NCT02393157 | RECRUITING | Non-Hodgkin Lymphoma; Burkitt Lymphoma; Diffuse Large B-Cell Lymphoma; Primary Mediastinal B-cell Lymphoma; CD20+ Lymphoblastic Lymphoma; Follicular Lymphoma, Grade III |
New York Medical College |
2015-08-21 | PHASE2 |
| NCT03805022 | RECRUITING | Non-metastatic Soft-tissue Sarcoma; Resectable |
Institut Bergonié |
2019-02-14 | PHASE3 |
| NCT01871766 | ACTIVE_NOT_RECRUITING | Rhabdomyosarcoma |
St. Jude Children's Research Hospital |
2013-12-04 | PHASE2 |
| NCT06302465 | RECRUITING | Malignant Bone Tumor |
Peking University People's Hospital |
2024-05-01 | |
| NCT04221035 | RECRUITING | High-Risk Neuroblastoma; Patient With Insufficient Response Chemoimmunotherapy |
Gustave Roussy, Cancer Campus, Grand Paris |
2019-11-05 | PHASE3 |
| NCT05124951 | RECRUITING | Intracranial Germ Cell CNS Tumor, Childhood |
Beijing Tiantan Hospital |
2021-09-15 | PHASE2 |
| NCT04776525 | RECRUITING | Soft Tissue Sarcoma |
Oslo University Hospital |
2021-04-27 | PHASE2 |
| NCT03007147 | ACTIVE_NOT_RECRUITING | Acute Lymphoblastic Leukemia; B Acute Lymphoblastic Leukemia; Mixed Phenotype Acute Leukemia; T Acute Lymphoblastic Leukemia |
Children's Oncology Group |
2017-08-08 | PHASE3 |
| NCT06820957 | ACTIVE_NOT_RECRUITING | CIC-Rearranged Sarcoma; Metastatic Ewing Sarcoma; Metastatic High Grade Sarcoma; Metastatic Undifferentiated Round Cell Sarcoma; Metastatic Undifferentiated Sarcoma, Not Otherwise Specified; Round Cell Sarcoma With EWSR1-non-ETS Fusion; Sarcoma With BCOR Genetic Alterations |
Children's Oncology Group |
2025-11-10 | PHASE2; PHASE3 |
| NCT05221645 | ACTIVE_NOT_RECRUITING | Diffuse Large B Cell Lymphoma |
University of Southampton |
2022-06-27 | PHASE2 |
| NCT05813327 | TERMINATED | Soft Tissue Sarcoma; Sts; Sarcoma,Soft Tissue |
Washington University School of Medicine |
2024-03-14 | PHASE1 |
| NCT04824352 | SUSPENDED | Effect of Drug; Toxicity, Drug |
Peking University People's Hospital |
2021-04-01 | PHASE2 |
| NCT05821088 | ACTIVE_NOT_RECRUITING | Recurrent B-Cell Lymphoma, Unclassifiable, With Features Intermediate Between Diffuse Large B-Cell Lymphoma and Classic Hodgkin Lymphoma; Recurrent Diffuse Large B-Cell Lymphoma, Not Otherwise Specified; Recurrent Grade 3b Follicular Lymphoma; Recurrent High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements; Recurrent High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements; Recurrent High Grade B-Cell Lymphoma, Not Otherwise Specified; Recurrent Primary Cutaneous Diffuse Large B-Cell Lymphoma, Leg Type; Recurrent Primary Mediastinal (Thymic) Large B-Cell Lymphoma; Recurrent T-Cell/Histiocyte-Rich Large B-Cell Lymphoma; Recurrent Transformed Follicular Lymphoma to Diffuse Large B-Cell Lymphoma; Recurrent Transformed Marginal Zone Lymphoma to Diffuse Large B-Cell Lymphoma; Refractory B-Cell Lymphoma, Unclassifiable, With Features Intermediate Between Diffuse Large B-Cell Lymphoma and Classic Hodgkin Lymphoma; Refractory Diffuse Large B-Cell Lymphoma, Not Otherwise Specified; Refractory Grade 3b Follicular Lymphoma; Refractory High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements; Refractory High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements; Refractory High Grade B-Cell Lymphoma, Not Otherwise Specified; Refractory Primary Cutaneous Diffuse Large B-Cell Lymphoma, Leg Type; Refractory Primary Mediastinal (Thymic) Large B-Cell Lymphoma; Refractory T-Cell/Histiocyte-Rich Large B-Cell Lymphoma; Refractory Transformed Follicular Lymphoma to Diffuse Large B-Cell Lymphoma; Refractory Transformed Marginal Zone Lymphoma to Diffuse Large B-Cell Lymphoma |
David Bond, MD |
2023-06-29 | PHASE2 |
| NCT06277154 | RECRUITING | Leiomyosarcoma; Liposarcoma; Synovial Sarcoma; Angiosarcoma; Undifferentiated Pleomorphic Sarcoma; Epithelioid Sarcoma; Malignant Peripheral Nerve Sheath Tumors; Fibrosarcoma; Pleomorphic Rhabdomyosarcoma; Endometrial Stromal Sarcoma; Desmoplastic Small Round Cell Tumor |
HRYZ Biotech Co. |
2024-02-21 | PHASE2 |
| NCT06816771 | RECRUITING | Rhabdomyosarcoma, Recurrent, Refractory |
Shandong Cancer Hospital and Institute |
2025-02 | PHASE2 |
| NCT03383406 | UNKNOWN | Diffuse Large B Cell Lymphoma |
Asan Medical Center |
2016-12-01 | PHASE2 |
| NCT04589754 | UNKNOWN | Soft Tissue Sarcoma |
Sun Yat-sen University |
2021-07-26 | PHASE2 |
| NCT04425070 | TERMINATED | Peripheral T-cell Lymphoma; NK/T-cell Lymphoma |
Antengene Corporation |
2020-08-18 | PHASE1; PHASE2 |
| NCT04833114 | COMPLETED | Relapsed Diffuse Large B-cell Lymphoma; Refractory Diffuse Large B-Cell Lymphoma |
GWT-TUD GmbH |
2021-04-30 | PHASE3 |
| NCT01464606 | ACTIVE_NOT_RECRUITING | Pleuropulmonary Blastoma |
Children's Hospitals and Clinics of Minnesota |
2009-12-22 | |
| NCT05844813 | ENROLLING_BY_INVITATION | Retroperitoneal Sarcoma |
Peking University International Hospital |
2022-11-01 | PHASE4 |
| NCT06164327 | UNKNOWN | Relapsed/Refractory Diffuse Large B-Cell Lymphoma |
BeBetter Med Inc |
2023-12-01 | PHASE1 |
| NCT05364424 | COMPLETED | Diffuse Large B-Cell Lymphoma (DLBCL) |
Hoffmann-La Roche |
2022-11-04 | PHASE1 |
| NCT04968106 | ACTIVE_NOT_RECRUITING | Resectable Sarcoma |
Institut Bergonié |
2022-12-07 | PHASE2 |
| NCT05455918 | RECRUITING | Pediatric Germ Cell Tumor |
Yonsei University |
2020-07-26 | PHASE2 |
| NCT05518383 | RECRUITING | Non-hodgkin Lymphoma,B Cell; Burkitt Lymphoma; Primary Mediastinal Lymphoma; Primary CNS Lymphoma; Diffuse Large B-cell Lymphoma |
Federal Research Institute of Pediatric Hematology, Oncology and Immunology |
2022-05-25 | PHASE4 |
| NCT03458260 | COMPLETED | Aggressive Non-Hodgkin Lymphoma |
The Lymphoma Academic Research Organisation |
2018-12-26 | PHASE2 |
| NCT01602666 | COMPLETED | Central Nervous System Nongerminomatous Germ Cell Tumor; Childhood Germinoma |
Children's Oncology Group |
2012-06-27 | PHASE2 |
| NCT01710176 | COMPLETED | Localized High-risk Soft Tissue Sarcomas of the Extremities and Trunk Wall in Adults |
Italian Sarcoma Group |
2011-06-01 | PHASE3 |
| NCT03277924 | COMPLETED | Soft Tissue Sarcoma; Bone Sarcoma |
Grupo Espanol de Investigacion en Sarcomas |
2017-05-31 | PHASE1; PHASE2 |
| NCT00878254 | COMPLETED | Mantle-Cell Lymphoma |
University of Miami |
2009-03-25 | PHASE2 |
| NCT03440567 | COMPLETED | Recurrent Diffuse Large B-Cell Lymphoma; Recurrent Mantle Cell Lymphoma; Refractory Diffuse Large B-Cell Lymphoma; Refractory Mantle Cell Lymphoma; Transformed Follicular Lymphoma to Diffuse Large B-Cell Lymphoma |
City of Hope Medical Center |
2018-04-02 | PHASE1 |
| NCT04860674 | UNKNOWN | Gray Zone Lymphoma; Relapse/Recurrence; Chemotherapy Effect |
Zhejiang Cancer Hospital |
2021-05-01 | PHASE2 |
| NCT01505569 | COMPLETED | Ewing's Family Tumors; Renal Tumors; Hepatoblastoma; Rhabdomyosarcoma; Soft Tissue Sarcoma; Primary Malignant Brain Neoplasms; Retinoblastoma; Medulloblastoma; Supra-tentorial Primative Neuro-Ectodermal Tumor (PNET); Atypical Teratoid/Rhabdoid Tumor (AT/RT); CNS Tumors; Germ Cell Tumors |
Masonic Cancer Center, University of Minnesota |
2011-10-20 | |
| NCT03016871 | ACTIVE_NOT_RECRUITING | Recurrent Hodgkin Lymphoma; Refractory Hodgkin Lymphoma |
City of Hope Medical Center |
2017-04-24 | PHASE2 |
| NCT00936936 | COMPLETED | Testicular Cancer |
M.D. Anderson Cancer Center |
2009-06-02 | PHASE2 |
| NCT02845882 | ACTIVE_NOT_RECRUITING | Lymphoblastic Lymphoma |
Children's Cancer Group, China |
2016-01 | PHASE3 |
| NCT03034304 | TERMINATED | Advanced Solid Tumors |
HRYZ Biotech Co. |
2017-02-22 | PHASE1 |
| NCT04581265 | UNKNOWN | Extracranial Germ Cell Tumor, Pediatric |
Sun Yat-sen University |
2020-11-10 | PHASE2 |
| NCT04981899 | UNKNOWN | Hodgkin Lymphoma |
St. Petersburg State Pavlov Medical University |
2021-03-01 | PHASE1; PHASE2 |
| NCT03736616 | UNKNOWN | Diffuse Large B Cell Lymphoma |
Swedish Medical Center |
2019-08-16 | PHASE2 |
| NCT04224337 | COMPLETED | Carcinoma, Non-Small-Cell Lung |
Seoul National University Hospital |
2020-06-11 | PHASE2 |
| NCT04044222 | UNKNOWN | Classic Hodgkin's Lymphoma |
Innovent Biologics (Suzhou) Co. Ltd. |
2019-10-21 | PHASE3 |
| NCT02348216 | COMPLETED | Refractory Diffuse Large B Cell Lymphoma (DLBCL); Relapsed Diffuse Large B-Cell Lymphoma; Transformed Follicular Lymphoma (TFL); Primary Mediastinal B-cell Lymphoma (PMBCL); High Grade B-cell Lymphoma (HGBCL) |
Kite, A Gilead Company |
2015-04-21 | PHASE1; PHASE2 |
| NCT06438614 | COMPLETED | Refractory Neuroblastoma; Soft Tissue Cancer |
Fundació Sant Joan de Déu |
2020-08-20 | PHASE2 |
| NCT03628131 | UNKNOWN | Relapsed Pediatric Solid Tumor; Refractory Pediatric Solid Tumor |
Samsung Medical Center |
2018-10 | PHASE1; PHASE2 |
| NCT05277480 | COMPLETED | Effect of Drug; Drug; Toxicity |
Peking University People's Hospital |
2022-03-01 | PHASE2 |
| NCT04012827 | UNKNOWN | Soft Tissue Sarcoma |
Sun Yat-sen University |
2019-08-20 | PHASE2 |
| NCT04925089 | Recruiting | Leiomyosarcoma |
University of Michigan Rogel Cancer Center|National Cancer Institute (NCI) |
2023-04-26 | -- |
| NCT04968106 | Recruiting | Resectable Sarcoma |
Institut Bergonié|Incyte Biosciences International Sàrl |
2022-12-07 | Phase 2 |
| NCT03064867 | ACTIVE_NOT_RECRUITING | Diffuse Large B-cell-lymphoma |
Molly Gallogly |
2017-06-26 | PHASE1; PHASE2 |
| NCT00574496 | COMPLETED | Lymphoma |
Memorial Sloan Kettering Cancer Center |
2007-11-13 | PHASE2 |
| NCT05050630 | UNKNOWN | Age Range ≥16 Years, Gender Unlimited; Histopathology Confirmed Diffuse Large B-cell Lymphoma or High-grade B-cell Lymphoma; Received Prior First-line Chemotherapy for DLBCL or HGBL, Failed to Reach CR for Four Cycles, or Relapsed; At Least One Positive Lesion According to the 2014 Lugano Criteria for Hodgkin's and Non-Hodgkin's Lymphoma; ECOG Physical Status Score is 0-3; The Researchers Judged That Life Expectancy Was at Least Three Months; Understand and Voluntarily Sign Written Informed Consent |
Affiliated Hospital to Academy of Military Medical Sciences |
2021-08-01 | PHASE2 |
| NCT04665765 | ACTIVE_NOT_RECRUITING | Diffuse Large B-Cell Lymphoma Unclassifiable; Recurrent Diffuse Large B-Cell Lymphoma; Recurrent Primary Mediastinal (Thymic) Large B-Cell Cell Lymphoma; Recurrent Transformed B-Cell Non-Hodgkin Lymphoma; Refractory Diffuse Large B-Cell Lymphoma; Refractory Primary Mediastinal (Thymic) Large B-Cell Cell Lymphoma; Refractory Transformed B-Cell Non-Hodgkin Lymphoma |
City of Hope Medical Center |
2021-01-18 | PHASE2 |
| NCT04154189 | COMPLETED | Osteosarcoma |
Eisai Inc. |
2020-03-23 | PHASE2 |
| NCT01979393 | COMPLETED | Uterine Sarcoma |
European Organisation for Research and Treatment of Cancer - EORTC |
2015-02-02 | PHASE2 |
| NCT04475016 | COMPLETED | Penile Cancer |
Sun Yat-sen University |
2020-08-12 | PHASE2 |
| NCT04356872 | UNKNOWN | Sarcoma, Soft Tissue |
Fudan University |
2020-04-08 | PHASE2 |
| NCT01117441 | COMPLETED | Leukemia |
University Hospital Schleswig-Holstein |
2010-06 | PHASE3 |
| NCT02638428 | UNKNOWN | Relapsed Pediatric Solid Tumor; Refractory Pediatric Solid Tumor; Relapsed Pediatric AML; Refractory Pediatric AML |
Samsung Medical Center |
2015-12 | PHASE2 |
| NCT00324467 | UNKNOWN | Lymphoma, Non-Hodgkin; Advanced Stage Diffuse Large B-Cell Non-Hodgkin's Lymphoma |
British Columbia Cancer Agency |
2006-08 | PHASE2 |
| NCT02104986 | COMPLETED | Extra Cranial Non Seminomateous Malignant Germ Cell Tumour |
Centre Leon Berard |
2014-05-12 | PHASE2 |
| NCT04044378 | WITHDRAWN | Effect of Drugs; Progression; Pediatric Cancer |
Peking University People's Hospital |
2019-08-15 | PHASE1; PHASE2 |
| NCT02628405 | UNKNOWN | Recurrent B-Cell Non-Hodgkin Lymphoma; Recurrent Diffuse Large B-Cell Lymphoma; Recurrent Primary Mediastinal (Thymic) Large B-Cell Lymphoma; Recurrent Transformed Non-Hodgkin Lymphoma; Refractory B-Cell Non-Hodgkin Lymphoma; Refractory Diffuse Large B-Cell Lymphoma; Refractory Primary Mediastinal (Thymic) Large B-Cell Lymphoma; Refractory Transformed Non-Hodgkin Lymphoma |
Academic and Community Cancer Research United |
2016-05-20 | PHASE1; PHASE2 |
| NCT02544425 | UNKNOWN | Extranodal NK-T-Cell Lymphoma |
Samsung Medical Center |
2016-02-21 | PHASE2 |
| NCT03071822 | UNKNOWN | Peripheral T Cell Lymphoma |
The University of Hong Kong |
2017-02-24 | PHASE4 |
| NCT04189952 | TERMINATED | Diffuse Large B Cell Lymphoma; Chronic Lymphocytic Leukemia; Small Lymphocytic Leukemia; Marginal Zone Lymphoma |
University of Miami |
2020-09-22 | PHASE2 |
| NCT03711279 | TERMINATED | Sarcoma |
Jiangsu HengRui Medicine Co., Ltd. |
2018-11-22 | PHASE2 |
| NCT02703272 | TERMINATED | Lymphoma, Non-Hodgkin |
Janssen Research & Development, LLC |
2016-07-01 | PHASE3 |
| NCT02018861 | COMPLETED | B-Cell Malignancies |
Incyte Corporation |
2016-09-22 | PHASE1; PHASE2 |
| NCT02306161 | ACTIVE_NOT_RECRUITING | Metastatic Ewing Sarcoma; Metastatic Malignant Neoplasm in the Bone; Metastatic Malignant Neoplasm in the Bone Marrow; Metastatic Malignant Neoplasm in the Lung; Metastatic Peripheral Primitive Neuroectodermal Tumor of Bone; Peripheral Primitive Neuroectodermal Tumor of Soft Tissues |
National Cancer Institute (NCI) |
2014-12-12 | PHASE3 |
| NCT01979536 | COMPLETED | Anaplastic Large Cell Lymphoma, ALK-Positive; Ann Arbor Stage II Noncutaneous Childhood Anaplastic Large Cell Lymphoma; Ann Arbor Stage III Noncutaneous Childhood Anaplastic Large Cell Lymphoma; Ann Arbor Stage IV Noncutaneous Childhood Anaplastic Large Cell Lymphoma |
National Cancer Institute (NCI) |
2013-11-13 | PHASE2 |
| NCT00712582 | COMPLETED | Non-Hodgkin's Lymphoma |
Memorial Sloan Kettering Cancer Center |
2008-07-01 | PHASE2 |
| NCT04690231 | COMPLETED | Effect of Drug; Toxicity, Drug; Secondary Resistance |
Peking University People's Hospital |
2020-12-01 | |
| NCT00432094 | COMPLETED | Childhood Germ Cell Tumor; Ovarian Cancer; Teratoma |
Masonic Cancer Center, University of Minnesota |
2006-12-19 | PHASE2 |
| NCT03349346 | WITHDRAWN | Diffuse Large B-Cell Lymphoma; Mediastinal B-cell Lymphoma |
Gilead Sciences |
2019-06 | PHASE1 |
| NCT03154918 | UNKNOWN | Lymphoma, Extranodal NK-T-Cell |
Sichuan University |
2017-06-01 | PHASE2 |
| NCT03077828 | UNKNOWN | Lymphocyte-Rich Classical Hodgkin Lymphoma; Recurrent Lymphocyte-Depleted Classical Hodgkin Lymphoma; Recurrent Mixed Cellularity Classical Hodgkin Lymphoma; Recurrent Nodular Sclerosis Classical Hodgkin Lymphoma; Refractory Lymphocyte-Depleted Classical Hodgkin Lymphoma; Refractory Mixed Cellularity Classical Hodgkin Lymphoma; Refractory Nodular Sclerosis Classical Hodgkin Lymphoma |
Northwestern University |
2017-04-21 | PHASE2 |
| NCT03367143 | UNKNOWN | Diffuse Large B-Cell Lymphoma Refractory |
Ruijin Hospital |
2016-12 | PHASE2 |
| NCT03268772 | UNKNOWN | Soft Tissue Sarcoma |
Fudan University |
2015-04-01 | PHASE2 |
| NCT03514381 | COMPLETED | Soft Tissue Sarcoma |
Institut Claudius Regaud |
2018-05-18 | PHASE4 |
| NCT03342300 | WITHDRAWN | Progression-free Survival; Overall Survival; Toxicity |
Peking University People's Hospital |
2017-11-06 | PHASE2; PHASE3 |
| NCT02808247 | TERMINATED | Sarcoma, Soft Tissue |
European Organisation for Research and Treatment of Cancer - EORTC |
2017-07-07 | PHASE2 |
| NCT03212937 | COMPLETED | Peripheral T-cell Lymphoma |
National Cancer Centre, Singapore |
2016-07-01 | PHASE1 |
| NCT00864318 | COMPLETED | Germ Cell Tumors |
Institut Claudius Regaud |
2009-03-13 | PHASE2 |
| NCT02422563 | UNKNOWN | Cervical Cancer |
Charite University, Berlin, Germany |
2015-10 | PHASE3 |
| NCT02732015 | TERMINATED | Locally Advanced Sarcoma |
M.D. Anderson Cancer Center |
2016-10-12 | PHASE2 |
| NCT01959698 | ACTIVE_NOT_RECRUITING | CD20 Positive; Recurrent Diffuse Large B-Cell Lymphoma; Refractory Diffuse Large B-Cell Lymphoma; Stage I Diffuse Large B-Cell Lymphoma; Stage II Diffuse Large B-Cell Lymphoma; Stage III Diffuse Large B-Cell Lymphoma; Stage IV Diffuse Large B-Cell Lymphoma |
Roswell Park Cancer Institute |
2014-04-17 | PHASE1 |
| NCT02414685 | COMPLETED | Germ Cell Tumor |
National Cancer Institute, Slovakia |
2015-04 | PHASE2 |
| NCT02099188 | UNKNOWN | Unresectable Sinonasal Tumors |
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano |
2013-11 | PHASE2 |
| NCT02784015 | UNKNOWN | Unresectable Localized Soft Tissue Sarcoma |
Samsung Medical Center |
2016-05 | PHASE2 |
| NCT01231906 | COMPLETED | Localized Extraskeletal Ewing Sarcoma; Peripheral Primitive Neuroectodermal Tumor of Bone; Peripheral Primitive Neuroectodermal Tumor of Soft Tissues |
Children's Oncology Group |
2010-11-24 | PHASE3 |
| NCT02112916 | ACTIVE_NOT_RECRUITING | Adult T Acute Lymphoblastic Leukemia; Ann Arbor Stage II Adult Lymphoblastic Lymphoma; Ann Arbor Stage II Childhood Lymphoblastic Lymphoma; Ann Arbor Stage III Adult Lymphoblastic Lymphoma; Ann Arbor Stage III Childhood Lymphoblastic Lymphoma; Ann Arbor Stage IV Adult Lymphoblastic Lymphoma; Ann Arbor Stage IV Childhood Lymphoblastic Lymphoma; Childhood T Acute Lymphoblastic Leukemia |
National Cancer Institute (NCI) |
2014-10-04 | PHASE3 |
| NCT02227199 | COMPLETED | Recurrent Hodgkin Lymphoma; Refractory Hodgkin Lymphoma |
University of Washington |
2014-10-10 | PHASE1; PHASE2 |
| NCT03623087 | UNKNOWN | Non-Hodgkin's Lymphoma, Relapsed; Non-Hodgkin T-cell Lymphoma; Natural Killer/T-Cell Lymphoma, Nasal and Nasal-Type |
The University of Hong Kong |
2017-07-01 | PHASE3 |
| NCT02771743 | UNKNOWN | Newly Diagnosed High Risk Neuroblastoma |
Samsung Medical Center |
2015-04 | PHASE2 |
| NCT03360760 | UNKNOWN | Osteosarcoma of Pelvis |
Peking University People's Hospital |
2018-08-01 | |
| NCT02099175 | UNKNOWN | Sinonasal Tumors |
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano |
2013-11 | PHASE2 |
| NCT04126811 | UNKNOWN | Soft Tissue Sarcoma |
Tianjin Medical University Cancer Institute and Hospital |
2019-06-01 | PHASE2 |
| NCT03815474 | UNKNOWN | Sarcoma, Soft Tissue |
Liaoning Cancer Hospital & Institute |
2019-05-20 | PHASE2 |
| NCT03651375 | UNKNOWN | Sarcoma; Fibrosarcoma; Leiomyosarcoma; Liposarcoma; Myosarcoma; Histiocytic Sarcoma; Synovial Sarcoma; Lymphangiosarcoma; Malignant Peripheral Nerve Sheath Tumors; Myxofibrosarcoma; Myxoid Liposarcoma; Undifferentiated Sarcoma; Pleomorphic Liposarcoma; Undifferentiated Pleomorphic Sarcoma; Dedifferentiated Liposarcoma; Pleomorphic Rhabdomyosarcoma; Malignant Triton Tumor |
Maria Sklodowska-Curie National Research Institute of Oncology |
2017-02-11 | PHASE2 |
| NCT02471911 | COMPLETED | Diffuse Large B-Cell Lymphoma |
Weill Medical College of Cornell University |
2015-12-11 | PHASE1 |
| NCT02329080 | COMPLETED | Diffuse Large B-cell Lymphoma |
International Extranodal Lymphoma Study Group (IELSG) |
2014-12 | PHASE2 |
| NCT01329900 | COMPLETED | Lymphoma |
M.D. Anderson Cancer Center |
2011-08-22 | PHASE2 |
| NCT02432274 | COMPLETED | Tumors; Solid Malignant Tumors; Osteosarcoma; Differentiated Thyroid Cancer (DTC) |
Eisai Limited |
2014-12-29 | PHASE1; PHASE2 |
| NCT02393859 | COMPLETED | Leukemia, Acute Lymphoblastic |
Amgen |
2015-11-10 | PHASE3 |
| NCT02180867 | COMPLETED | Alveolar Soft Part Sarcoma; Angiomatoid Fibrous Histiocytoma; Atypical Fibroxanthoma; Clear Cell Sarcoma of Soft Tissue; Epithelioid Malignant Peripheral Nerve Sheath Tumor; Epithelioid Sarcoma; Extraskeletal Myxoid Chondrosarcoma; Extraskeletal Osteosarcoma; Fibrohistiocytic Neoplasm; Fibrosarcoma; Inflammatory Myofibroblastic Tumor; Intimal Sarcoma; Leiomyosarcoma; Liposarcoma; Liver Embryonal Sarcoma; Low Grade Fibromyxoid Sarcoma; Low Grade Myofibroblastic Sarcoma; Malignant Peripheral Nerve Sheath Tumor; Malignant Skin Granular Cell Tumor; Malignant Triton Tumor; Mesenchymal Chondrosarcoma; Myxofibrosarcoma; Myxoid Chondrosarcoma; Myxoinflammatory Fibroblastic Sarcoma; Nerve Sheath Neoplasm; PEComa; Pericytic Neoplasm; Plexiform Fibrohistiocytic Tumor; Sclerosing Epithelioid Fibrosarcoma; Skin Glomus Tumor; Stage IB Soft Tissue Sarcoma AJCC v7; Stage IIB Soft Tissue Sarcoma AJCC v7; Stage III Soft Tissue Sarcoma AJCC v7; Stage IV Soft Tissue Sarcoma AJCC v7; Synovial Sarcoma; Undifferentiated High Grade Pleomorphic Sarcoma of Bone |
National Cancer Institute (NCI) |
2014-08-12 | PHASE2; PHASE3 |
| NCT03283696 | COMPLETED | Soft Tissue Sarcoma |
Eli Lilly and Company |
2017-10-18 | PHASE1 |
| NCT00954174 | UNKNOWN | Mixed Mesodermal (Mullerian) Tumor; Ovarian Carcinosarcoma; Recurrent Fallopian Tube Carcinoma; Recurrent Ovarian Carcinoma; Recurrent Primary Peritoneal Carcinoma; Stage I Ovarian Cancer AJCC v6 and v7; Stage IA Fallopian Tube Cancer AJCC v6 and v7; Stage IA Ovarian Cancer AJCC v6 and v7; Stage IA Uterine Sarcoma AJCC v7; Stage IB Fallopian Tube Cancer AJCC v6 and v7; Stage IB Ovarian Cancer AJCC v6 and v7; Stage IB Uterine Sarcoma AJCC v7; Stage IC Fallopian Tube Cancer AJCC v6 and v7; Stage IC Ovarian Cancer AJCC v6 and v7; Stage IC Uterine Sarcoma AJCC v7; Stage II Ovarian Cancer AJCC v6 and v7; Stage IIA Fallopian Tube Cancer AJCC v6 and v7; Stage IIA Ovarian Cancer AJCC V6 and v7; Stage IIA Uterine Sarcoma AJCC v7; Stage IIB Fallopian Tube Cancer AJCC v6 and v7; Stage IIB Ovarian Cancer AJCC v6 and v7; Stage IIB Uterine Sarcoma AJCC v7; Stage IIC Fallopian Tube Cancer AJCC v6 and v7; Stage IIC Ovarian Cancer AJCC v6 and v7; Stage IIIA Fallopian Tube Cancer AJCC v7; Stage IIIA Ovarian Cancer AJCC v6 and v7; Stage IIIA Primary Peritoneal Cancer AJCC v7; Stage IIIA Uterine Sarcoma AJCC v7; Stage IIIB Fallopian Tube Cancer AJCC v7; Stage IIIB Ovarian Cancer AJCC v6 and v7; Stage IIIB Primary Peritoneal Cancer AJCC v7; Stage IIIB Uterine Sarcoma AJCC v7; Stage IIIC Fallopian Tube Cancer AJCC v7; Stage IIIC Ovarian Cancer AJCC v6 and v7; Stage IIIC Primary Peritoneal Cancer AJCC v7; Stage IIIC Uterine Sarcoma AJCC v7; Stage IV Fallopian Tube Cancer AJCC v6 and v7; Stage IV Ovarian Cancer AJCC v6 and v7; Stage IV Primary Peritoneal Cancer AJCC v7; Stage IVA Uterine Sarcoma AJCC v7; Stage IVB Uterine Sarcoma AJCC v7; Uterine Carcinosarcoma |
GOG Foundation |
2009-08-17 | PHASE3 |
| NCT01966913 | UNKNOWN | Germ Cell Tumor |
Assistance Publique - Hôpitaux de Paris |
2012-04 | PHASE1; PHASE2 |
| NCT02718482 | TERMINATED | OSTEOSARCOMA |
Italian Sarcoma Group |
2016-04-06 | PHASE2 |
| NCT01446809 | COMPLETED | Stage IIA Adult Soft Tissue Sarcoma; Stage III Adult Soft Tissue Sarcoma; Stage IV Adult Soft Tissue Sarcoma |
University of Washington |
2012-04 | |
| NCT02812654 | UNKNOWN | Sarcoma, Soft Tissue |
AC Camargo Cancer Center |
2015-03 | PHASE2 |
| NCT02686346 | COMPLETED | Hodgkin Disease |
The Lymphoma Academic Research Organisation |
2016-03 | PHASE1; PHASE2 |
| NCT02677116 | COMPLETED | Neoplasm Metastasis |
Eli Lilly and Company |
2016-08-29 | PHASE1 |
| NCT01424839 | UNKNOWN | Intracranial Germ Cell Tumors |
University Hospital Muenster |
2011-10 | PHASE4 |
| NCT01746992 | UNKNOWN | ALK-negative Anaplastic Large Cell Lymphoma; Peripherial T Cell Lymphoma,Not Otherwise Specified; Angioimmunoblastic T Cell Lymphoma; Enteropathy Associated T Cell Lymphoma; Hepatosplenic T Cell Lymphoma; Subcutaneous Panniculitis Like T Cell Lymphoma |
Ruijin Hospital |
2012-09 | PHASE4 |
| NCT01784107 | UNKNOWN | Small Cell Lung Cancer |
Gachon University Gil Medical Center |
2011-07 | PHASE1; PHASE2 |
| NCT02050919 | COMPLETED | Pleomorphic Rhabdomyosarcoma; Stage IIB Adult Soft Tissue Sarcoma AJCC v7; Stage III Adult Soft Tissue Sarcoma AJCC v7; Stage IV Adult Soft Tissue Sarcoma AJCC v7 |
OHSU Knight Cancer Institute |
2013-12-03 | PHASE2 |
| NCT00967369 | COMPLETED | Recurrent Classic Hodgkin Lymphoma; Refractory Classic Hodgkin Lymphoma |
M.D. Anderson Cancer Center |
2009-08-24 | PHASE2 |
| NCT01590732 | COMPLETED | Mycosis Fungoides; Recurrent Anaplastic Large Cell Lymphoma; Recurrent Angioimmunoblastic T-Cell Lymphoma; Recurrent Enteropathy-Associated T-Cell Lymphoma; Recurrent Hepatosplenic T-Cell Lymphoma; Recurrent Peripheral T-Cell Lymphoma, Not Otherwise Specified; Refractory Anaplastic Large Cell Lymphoma; Refractory Angioimmunoblastic T-Cell Lymphoma; Refractory Enteropathy-Associated T-Cell Lymphoma; Refractory Hepatosplenic T-Cell Lymphoma; Refractory Peripheral T-Cell Lymphoma, Not Otherwise Specified |
M.D. Anderson Cancer Center |
2012-10-29 | PHASE1 |
| NCT02235701 | COMPLETED | Metastatic, Locally Advanced, or Unresectable Soft Tissue Sarcoma |
ImmunityBio, Inc. |
2014-09-02 | PHASE1; PHASE2 |
| NCT02592876 | TERMINATED | Lymphoma, B-cell; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Follicular, Grade 3b; Follicular Lymphoma, Grade 3b |
Seagen Inc. |
2015-10 | PHASE2 |
| NCT01795430 | WITHDRAWN | Adult Supratentorial Primitive Neuroectodermal Tumor (PNET); Ewing Sarcoma of Bone; Extraosseous Ewing Sarcoma; Metastatic Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor; Recurrent Childhood Supratentorial Primitive Neuroectodermal Tumor; Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor; Untreated Childhood Supratentorial Primitive Neuroectodermal Tumor |
City of Hope Medical Center |
2013-07 | |
| NCT01156883 | COMPLETED | Leukemia |
Gruppo Italiano Malattie EMatologiche dell'Adulto |
2010-04 | |
| NCT01169636 | COMPLETED | Hodgkin's Lymphoma |
M.D. Anderson Cancer Center |
2011-01-31 | PHASE1; PHASE2 |
| NCT02219737 | COMPLETED | CD20 Positive; Recurrent Diffuse Large B-Cell Lymphoma; Refractory Diffuse Large B-Cell Lymphoma |
National Cancer Institute (NCI) |
2014-09-12 | PHASE1 |
| NCT02137096 | TERMINATED | Recurrent Nasopharynx Carcinoma |
University of Florida |
2014-06 | PHASE3 |
| NCT02049905 | COMPLETED | Metastatic, Locally Advanced or Unresectable Soft Tissue Sarcoma |
ImmunityBio, Inc. |
2014-01 | PHASE3 |
| NCT00526318 | UNKNOWN | Neuroblastoma |
German Society for Pediatric Oncology and Hematology GPOH gGmbH |
2007-01 | |
| NCT01749072 | UNKNOWN | Non-small Cell Lung Cancer; Effects of Chemotherapy |
Peking Union Medical College Hospital |
2012-12 | PHASE2 |
| NCT02441309 | TERMINATED | Osteosarcoma |
University of Oxford |
2014-10 | PHASE2 |
| NCT02207309 | TERMINATED | Sarcoma |
Ludwig-Maximilians - University of Munich |
2015-06-22 | PHASE2 |
| NCT01055314 | COMPLETED | Adult Rhabdomyosarcoma; Childhood Alveolar Rhabdomyosarcoma; Childhood Embryonal Rhabdomyosarcoma; Metastatic Childhood Soft Tissue Sarcoma; Stage IV Adult Soft Tissue Sarcoma; Untreated Childhood Rhabdomyosarcoma |
National Cancer Institute (NCI) |
2010-01 | PHASE2 |
| NCT00470366 | COMPLETED | Brain and Central Nervous System Tumors; Extragonadal Germ Cell Tumor; Ovarian Cancer; Teratoma; Testicular Germ Cell Tumor |
Memorial Sloan Kettering Cancer Center |
2007-03 | PHASE2 |
| NCT01490060 | COMPLETED | Sarcoma; Chemotherapy-induced Nausea and Vomiting; Effects of Chemotherapy; Adverse Effects of Medical Drugs |
M.D. Anderson Cancer Center |
2012-05 | |
| NCT00920153 | TERMINATED | Lymphoma |
French Innovative Leukemia Organisation |
2008-05 | PHASE3 |
| NCT00470223 | ACTIVE_NOT_RECRUITING | Sarcoma |
UNICANCER |
2007-03 | PHASE3 |
| NCT01501136 | UNKNOWN | Nasal and Nasal-type NK/T-cell Lymphoma |
Mingzhi Zhang |
2011-01 | PHASE4 |
| NCT02412267 | COMPLETED | Diffuse Large B-cell Lymphoma |
National Cancer Centre, Singapore |
2011-04 | PHASE2 |
| NCT02408042 | WITHDRAWN | Lymphoma; Hodgkin's Lymphoma; Non-hodgkin's Lymphoma |
Western Regional Medical Center |
2015-04 | PHASE1; PHASE2 |
| NCT01946529 | COMPLETED | Desmoplastic Small Round Cell Tumor; Ewing Sarcoma of Bone or Soft Tissue; Localized Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor; Metastatic Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor |
St. Jude Children's Research Hospital |
2013-12-27 | PHASE2 |
| NCT00002854 | COMPLETED | Cancer |
City of Hope Medical Center |
1994-12 | PHASE1 |
| NCT00450801 | COMPLETED | Lymphoma |
University of Miami |
2004-04 | PHASE2 |
| NCT01555710 | UNKNOWN | Extensive-Stage Small Cell Lung Cancer |
Alaunos Therapeutics |
2012-05 | PHASE3 |
| NCT00134030 | COMPLETED | Localized Osteosarcoma; Metastatic Osteosarcoma |
Children's Oncology Group |
2005-11-14 | PHASE3 |
| NCT00720109 | COMPLETED | Acute Lymphoblastic Leukemia; Adult B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1; Childhood B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1 |
National Cancer Institute (NCI) |
2008-07-14 | PHASE2; PHASE3 |
| NCT02432274 | Completed | Tumors|Solid Malignant Tumors|Osteosarcoma|Differentiated Thyroid Cancer (DTC) |
Eisai Limited|Merck Sharp & Dohme LLC|Eisai Inc. |
2014-12-29 | Phase 1|Phase 2 |
| NCT01241734 | COMPLETED | Diffuse Large B Cell Lymphoma |
Hackensack Meridian Health |
2010-10 | PHASE1; PHASE2 |
| NCT00002931 | COMPLETED | Brain and Central Nervous System Tumors; Extragonadal Germ Cell Tumor; Ovarian Cancer; Teratoma; Testicular Germ Cell Tumor |
City of Hope Medical Center |
1997-02 | PHASE2 |
| NCT01238159 | COMPLETED | Extranodal NK-T-Cell Lymphoma, Nasal and Nasal-Type |
Samsung Medical Center |
2010-08 | PHASE2 |
| NCT01808534 | TERMINATED | Adult Central Nervous System Germ Cell Tumor; Adult Teratoma; Malignant Extragonadal Germ Cell Tumor; Malignant Extragonadal Non-Seminomatous Germ Cell Tumor; Extragonadal Seminoma; Recurrent Malignant Testicular Germ Cell Tumor; Recurrent Ovarian Germ Cell Tumor; Stage IV Extragonadal Non-Seminomatous Germ Cell Tumor; Stage IV Extragonadal Seminoma; Stage IV Ovarian Germ Cell Tumor |
Indiana University |
2013-02 | PHASE2 |
| NCT01226849 | COMPLETED | Diffuse Large B-Cell Lymphoma |
Singapore General Hospital |
2010-11 | PHASE1 |
| NCT00598169 | COMPLETED | Lymphoma |
AIDS Malignancy Consortium |
2007-11 | PHASE1 |
| NCT01331590 | COMPLETED | Precursor Cell Lymphoblastic Leukemia-Lymphoma |
Washington University School of Medicine |
2011-07 | EARLY_PHASE1 |
| NCT00346164 | COMPLETED | Adult Alveolar Soft-part Sarcoma; Adult Angiosarcoma; Adult Epithelioid Sarcoma; Adult Extraskeletal Chondrosarcoma; Adult Extraskeletal Osteosarcoma; Adult Fibrosarcoma; Adult Leiomyosarcoma; Adult Liposarcoma; Adult Malignant Fibrous Histiocytoma; Adult Malignant Hemangiopericytoma; Adult Malignant Mesenchymoma; Adult Neurofibrosarcoma; Adult Synovial Sarcoma; Childhood Alveolar Soft-part Sarcoma; Childhood Angiosarcoma; Childhood Epithelioid Sarcoma; Childhood Fibrosarcoma; Childhood Leiomyosarcoma; Childhood Liposarcoma; Childhood Malignant Mesenchymoma; Childhood Neurofibrosarcoma; Childhood Synovial Sarcoma; Dermatofibrosarcoma Protuberans; Metastatic Childhood Soft Tissue Sarcoma; Nonmetastatic Childhood Soft Tissue Sarcoma; Stage I Adult Soft Tissue Sarcoma; Stage II Adult Soft Tissue Sarcoma; Stage III Adult Soft Tissue Sarcoma; Stage IV Adult Soft Tissue Sarcoma |
Children's Oncology Group |
2007-02-05 | PHASE3 |
| NCT00002601 | COMPLETED | Sarcoma |
City of Hope Medical Center |
1994-09 | PHASE2 |
| NCT01703754 | TERMINATED | Breast Cancer Nos Metastatic Recurrent |
Alaunos Therapeutics |
2013-04-04 | PHASE2 |
| NCT00667342 | COMPLETED | Osteosarcoma; Malignant Fibrous Histiocytoma (MFH) of Bone |
St. Jude Children's Research Hospital |
2008-06-03 | PHASE2 |
| NCT00304083 | COMPLETED | Neurofibromatosis Type 1; Sarcoma |
Sarcoma Alliance for Research through Collaboration |
2005-12 | PHASE2 |
| NCT01872416 | UNKNOWN | Small Cell Lung Cancer |
The First Affiliated Hospital of Guangzhou Medical University |
2012-10 | PHASE2 |
| NCT00809341 | TERMINATED | Non-Hodgkin's Lymphoma |
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins |
2009-01 | PHASE2 |
| NCT01884428 | UNKNOWN | Hodgkin's Lymphoma |
Armando Santoro, MD |
2011-07 | PHASE1 |
| NCT00317408 | UNKNOWN | Lymphoma |
European Inter-group Cooperation on Childhood and Adolescent Non Hodgkin Lymphoma |
2004-04 | |
| NCT00658580 | COMPLETED | Small Cell Lung Carcinoma, Extensive Disease |
European Lung Cancer Working Party |
2000-04 | PHASE3 |
| NCT02808091 | TERMINATED | Extranodal NK-T-CELL LYMPHOMA |
National Cancer Centre, Singapore |
2011-03 | PHASE2 |
| NCT00662233 | COMPLETED | Ovarian Cancer; Sarcoma |
Mayo Clinic |
1991-10 | EARLY_PHASE1 |
| NCT01097057 | COMPLETED | Non-Hodgkin Lymphoma |
Fred Hutchinson Cancer Center |
2010-11-09 | PHASE2 |
| NCT01340547 | UNKNOWN | Advanced Solid Tumors |
Alaunos Therapeutics |
2011-06 | PHASE1 |
| NCT00346125 | COMPLETED | Sarcoma |
Masonic Cancer Center, University of Minnesota |
2006-04-10 | |
| NCT00541411 | UNKNOWN | Ewing's Sarcoma |
King Faisal Specialist Hospital & Research Center |
2003-06 | |
| NCT00274924 | COMPLETED | Lymphoma |
Eastern Cooperative Oncology Group |
2006-09-26 | PHASE2 |
| NCT00551122 | UNKNOWN | Brain and Central Nervous System Tumors; Extragonadal Germ Cell Tumor; Ovarian Cancer; Testicular Germ Cell Tumor |
University of Southampton |
2006-11 | PHASE1; PHASE2 |
| NCT00699517 | COMPLETED | Sarcoma |
Sanofi |
2008-06 | PHASE3 |
| NCT00020722 | TERMINATED | Breast Cancer |
Barbara Ann Karmanos Cancer Institute |
2007-08 | PHASE2 |
| NCT00147225 | COMPLETED | Solid Tumors; Advanced Cancer |
M.D. Anderson Cancer Center |
2005-08 | PHASE1; PHASE2 |
| NCT01168791 | COMPLETED | Soft Tissue Sarcoma |
Alaunos Therapeutics |
2010-07 | PHASE3 |
| NCT00423852 | COMPLETED | Brain and Central Nervous System Tumors; Extragonadal Germ Cell Tumor; Ovarian Cancer; Teratoma; Testicular Germ Cell Tumor |
Memorial Sloan Kettering Cancer Center |
2006-08 | PHASE1; PHASE2 |
| NCT01242072 | UNKNOWN | Malignancy; Cancer; Non Small Cell Lung Cancer; Small Cell Lung Cancer; Testicular Cancer; Thymoma; Ovarian Cancer; Osteosarcoma |
Alaunos Therapeutics |
2010-11 | PHASE1 |
| NCT00189137 | COMPLETED | Sarcoma, Soft Tissue |
University of Michigan Rogel Cancer Center |
2004-08 | PHASE2 |
| NCT01172912 | UNKNOWN | Brain and Central Nervous System Tumors; Extragonadal Germ Cell Tumor; Testicular Germ Cell Tumor |
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano |
2010-10 | PHASE2 |
| NCT00790244 | UNKNOWN | Soft Tissue Sarcoma; Non Metastatic Disease |
Oslo University Hospital |
2007-10 | PHASE2 |
| NCT01230788 | TERMINATED | Leukemia; Acute Lymphoblastic Leukemia; ALL |
Emory University |
2010-09 | |
| NCT00822848 | COMPLETED | Sarcoma |
OHSU Knight Cancer Institute |
2009-02 | PHASE1 |
| NCT00695032 | SUSPENDED | Chemotherapeutic Agent Toxicity; Renal Toxicity; Unspecified Adult Solid Tumor, Protocol Specific |
Institut Claudius Regaud |
2007-10 | |
| NCT00796120 | COMPLETED | Sarcoma |
Johnson & Johnson Pharmaceutical Research & Development, L.L.C. |
2008-11 | PHASE3 |
| NCT00623077 | TERMINATED | Brain and Central Nervous System Tumors; Kidney Cancer; Liver Cancer; Retinoblastoma; Sarcoma |
Masonic Cancer Center, University of Minnesota |
2005-08 | PHASE1 |
| NCT00255723 | COMPLETED | Lymphoma |
Memorial Sloan Kettering Cancer Center |
2004-04 | PHASE2 |
| NCT00439361 | COMPLETED | Hodgkin Lymphoma; Lymphoma |
M.D. Anderson Cancer Center |
2007-02 | PHASE1 |
| NCT00836173 | WITHDRAWN | Diffuse Large B-cell Lymphoma |
Loyola University |
2008-07 | PHASE2 |
| NCT00742924 | COMPLETED | Sarcoma |
Children's Oncology Group |
2008-08 | PHASE1 |
| NCT00718484 | UNKNOWN | Soft Tissue Sarcoma |
Alaunos Therapeutics |
2008-08 | PHASE2 |
| NCT00104676 | COMPLETED | Extragonadal Germ Cell Tumor; Teratoma; Testicular Germ Cell Tumor |
UNICANCER |
2003-11-26 | PHASE3 |
| NCT00467051 | COMPLETED | Childhood Extracranial Germ Cell Tumor; Childhood Extragonadal Malignant Germ Cell Tumor; Childhood Malignant Ovarian Germ Cell Tumor; Childhood Malignant Testicular Germ Cell Tumor; Ovarian Choriocarcinoma; Ovarian Embryonal Carcinoma; Ovarian Yolk Sac Tumor; Recurrent Childhood Malignant Germ Cell Tumor; Recurrent Malignant Testicular Germ Cell Tumor; Recurrent Ovarian Germ Cell Tumor; Testicular Choriocarcinoma; Testicular Embryonal Carcinoma; Testicular Mixed Choriocarcinoma and Embryonal Carcinoma; Testicular Mixed Choriocarcinoma and Yolk Sac Tumor; Testicular Mixed Embryonal Carcinoma and Yolk Sac Tumor; Testicular Yolk Sac Tumor |
Children's Oncology Group |
2007-11-05 | PHASE2 |
| NCT01026220 | COMPLETED | Childhood Nodular Lymphocyte Predominant Hodgkin Lymphoma; Stage III Childhood Hodgkin Lymphoma; Stage IV Childhood Hodgkin Lymphoma |
Children's Oncology Group |
2009-12-07 | PHASE3 |
| NCT00302003 | COMPLETED | Childhood Favorable Prognosis Hodgkin Lymphoma; Childhood Lymphocyte Depletion Hodgkin Lymphoma; Childhood Mixed Cellularity Hodgkin Lymphoma; Childhood Nodular Sclerosis Hodgkin Lymphoma; Stage I Childhood Hodgkin Lymphoma; Stage II Childhood Hodgkin Lymphoma |
Children's Oncology Group |
2006-02 | PHASE3 |
| NCT00965172 | COMPLETED | Sarcoma; Oral Mucositis |
M.D. Anderson Cancer Center |
2010-04 | PHASE2 |
| NCT00430118 | COMPLETED | Leukemia |
University Hospital Schleswig-Holstein |
2000-07 | PHASE3 |
| NCT00101205 | TERMINATED | Angioimmunoblastic T-cell Lymphoma; B-cell Childhood Acute Lymphoblastic Leukemia; B-cell Chronic Lymphocytic Leukemia; Childhood Burkitt Lymphoma; Childhood Diffuse Large Cell Lymphoma; Childhood Grade III Lymphomatoid Granulomatosis; Childhood Immunoblastic Large Cell Lymphoma; Childhood Nasal Type Extranodal NK/T-cell Lymphoma; Hepatosplenic T-cell Lymphoma; Intraocular Lymphoma; Noncutaneous Extranodal Lymphoma; Peripheral T-cell Lymphoma; Recurrent Childhood Acute Lymphoblastic Leukemia; Recurrent Childhood Anaplastic Large Cell Lymphoma; Recurrent Childhood Grade III Lymphomatoid Granulomatosis; Recurrent Childhood Large Cell Lymphoma; Recurrent Childhood Lymphoblastic Lymphoma; Recurrent Childhood Small Noncleaved Cell Lymphoma; Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma; Recurrent Mycosis Fungoides/Sezary Syndrome; Recurrent/Refractory Childhood Hodgkin Lymphoma; Refractory Chronic Lymphocytic Leukemia; Refractory Hairy Cell Leukemia; Small Intestine Lymphoma; T-cell Childhood Acute Lymphoblastic Leukemia; T-cell Large Granular Lymphocyte Leukemia; Unspecified Childhood Solid Tumor, Protocol Specific |
National Cancer Institute (NCI) |
2004-11 | PHASE1 |
| NCT00801918 | WITHDRAWN | Anaplastic Large-Cell Lymphoma |
Columbia University |
2008-12 | PHASE2 |
| NCT00020566 | UNKNOWN | Sarcoma |
University of Leicester |
2001-02 | PHASE3 |
| NCT01258634 | TERMINATED | Osteosarcoma; Lung Metastases |
University of Chicago |
2010-07 | PHASE1 |
| NCT00544778 | TERMINATED | Sarcoma |
City of Hope Medical Center |
2001-08 | PHASE2 |
| NCT00515138 | TERMINATED | Lymphoma, B-Cell |
University of California, San Francisco |
2007-05 | EARLY_PHASE1 |
| NCT01102608 | COMPLETED | Soft Tissue Sarcoma |
Grupo Espanol de Investigacion en Sarcomas |
2008-03 | PHASE2 |
| NCT00089544 | TERMINATED | Recurrent Adult Soft Tissue Sarcoma; Stage I Adult Soft Tissue Sarcoma AJCC v7; Stage II Adult Soft Tissue Sarcoma AJCC v7; Stage III Adult Soft Tissue Sarcoma AJCC v7 |
National Cancer Institute (NCI) |
2004-06-17 | PHASE2 |
| NCT01300793 | TERMINATED | Non-Hodgkin's Lymphoma; B-cell Lymphoma |
University of California, San Francisco |
2007-05 | PHASE1 |
| NCT00231842 | COMPLETED | Uterine Cancer |
Montefiore Medical Center |
2003-02 | PHASE2 |
| NCT00392834 | COMPLETED | Lymphoma |
AIDS Malignancy Consortium |
2006-09 | PHASE2 |
| NCT00410488 | COMPLETED | Sarcoma; Nausea; Vomiting |
M.D. Anderson Cancer Center |
2006-12 | |
| NCT00379457 | UNKNOWN | Sarcoma |
European Paediatric Soft Tissue Sarcoma Study Group |
2006-06 | PHASE3 |
| NCT00974792 | UNKNOWN | Lymphoma |
Cancer Research UK |
2006-01 | PHASE2 |
| NCT00960063 | TERMINATED | Neoplasms; Solid Tumors; Bone Cancer; Kidney Tumor; Neuroblastoma |
Merck Sharp & Dohme LLC |
2009-11-11 | PHASE1 |
| NCT00504751 | COMPLETED | Non-Hodgkin's Lymphoma |
Weill Medical College of Cornell University |
2007-05 | PHASE2 |
| NCT00410631 | UNKNOWN | Neuroblastoma |
German Society for Pediatric Oncology and Hematology GPOH gGmbH |
2004-10 | PHASE3 |
| NCT00880542 | TERMINATED | Sarcoma |
Jonsson Comprehensive Cancer Center |
2008-08 | PHASE2 |
| NCT00673179 | TERMINATED | Osteosarcoma |
M.D. Anderson Cancer Center |
2008-05 | |
| NCT00358540 | COMPLETED | Thrombocytopaenia |
GlaxoSmithKline |
2006-06-01 | PHASE1 |
| NCT01458730 | COMPLETED | Central Nervous System Lymphoma |
University of Aarhus |
2007-05 | PHASE2 |
| NCT00039130 | COMPLETED | Leukemia; Lymphoma |
Alliance for Clinical Trials in Oncology |
2002-05 | PHASE2 |
| NCT00512096 | COMPLETED | Penile Cancer |
M.D. Anderson Cancer Center |
1999-08 | PHASE2 |
| NCT00601718 | COMPLETED | Adult Nasal Type Extranodal NK/T-cell Lymphoma; Anaplastic Large Cell Lymphoma; Angioimmunoblastic T-cell Lymphoma; Contiguous Stage II Mantle Cell Lymphoma; Cutaneous B-cell Non-Hodgkin Lymphoma; Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue; Nodal Marginal Zone B-cell Lymphoma; Noncontiguous Stage II Mantle Cell Lymphoma; Recurrent Adult Burkitt Lymphoma; Recurrent Adult Diffuse Large Cell Lymphoma; Recurrent Adult Diffuse Mixed Cell Lymphoma; Recurrent Adult Diffuse Small Cleaved Cell Lymphoma; Recurrent Adult Grade III Lymphomatoid Granulomatosis; Recurrent Adult Hodgkin Lymphoma; Recurrent Adult Immunoblastic Large Cell Lymphoma; Recurrent Adult Lymphoblastic Lymphoma; Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma; Recurrent Grade 1 Follicular Lymphoma; Recurrent Grade 2 Follicular Lymphoma; Recurrent Grade 3 Follicular Lymphoma; Recurrent Mantle Cell Lymphoma; Recurrent Marginal Zone Lymphoma; Recurrent Mycosis Fungoides/Sezary Syndrome; Recurrent Small Lymphocytic Lymphoma; Splenic Marginal Zone Lymphoma; Stage I Cutaneous T-cell Non-Hodgkin Lymphoma; Stage I Mantle Cell Lymphoma; Stage I Mycosis Fungoides/Sezary Syndrome; Stage II Cutaneous T-cell Non-Hodgkin Lymphoma; Stage II Mycosis Fungoides/Sezary Syndrome; Stage III Cutaneous T-cell Non-Hodgkin Lymphoma; Stage III Mantle Cell Lymphoma; Stage III Mycosis Fungoides/Sezary Syndrome; Stage IV Cutaneous T-cell Non-Hodgkin Lymphoma; Stage IV Mantle Cell Lymphoma; Stage IV Mycosis Fungoides/Sezary Syndrome; Waldenström Macroglobulinemia |
University of Washington |
2007-12 | PHASE1; PHASE2 |
| NCT00199082 | COMPLETED | Burkitt's Lymphoma; Burkitt's Leukemia; Mediastinal Neoplasms; Lymphoblastic Lymphoma; Large Cell Anaplastic Lymphoma |
Nicola Goekbuget |
2002-07 | PHASE4 |
| NCT00334854 | UNKNOWN | Childhood Malignant Fibrous Histiocytoma of Bone; Sarcoma |
European Paediatric Soft Tissue Sarcoma Study Group |
2006-03 | PHASE3 |
| NCT00274950 | UNKNOWN | Childhood Germ Cell Tumor; Extragonadal Germ Cell Tumor; Ovarian Cancer |
Children's Cancer and Leukaemia Group |
2005-05 | PHASE3 |
| NCT00061984 | COMPLETED | Sarcoma |
European Organisation for Research and Treatment of Cancer - EORTC |
2003-04 | PHASE3 |
| NCT00788125 | TERMINATED | Brain and Central Nervous System Tumors; Childhood Germ Cell Tumor; Extragonadal Germ Cell Tumor; Kidney Cancer; Liver Cancer; Lymphoma; Neuroblastoma; Ovarian Cancer; Sarcoma; Testicular Germ Cell Tumor; Unspecified Childhood Solid Tumor, Protocol Specific |
City of Hope Medical Center |
2008-09-03 | PHASE1; PHASE2 |
| NCT00003631 | COMPLETED | Lymphoma |
Memorial Sloan Kettering Cancer Center |
1998-08 | PHASE2 |
| NCT00618813 | COMPLETED | Ewing Sarcoma of Bone; Localized Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor |
Children's Oncology Group |
2008-03 | |
| NCT00278278 | UNKNOWN | Brain and Central Nervous System Tumors |
German Society for Pediatric Oncology and Hematology GPOH gGmbH |
2003-09 | PHASE3 |
| NCT00588094 | COMPLETED | Lymphoma; B-cell Non-Hodgkin's Lymphoma |
Memorial Sloan Kettering Cancer Center |
2003-10 | PHASE2 |
| NCT00354107 | TERMINATED | Anaplastic Large Cell Lymphoma; Recurrent Childhood Anaplastic Large Cell Lymphoma |
National Cancer Institute (NCI) |
2007-01 | PHASE1; PHASE2 |
| NCT00354744 | COMPLETED | Sarcoma |
Children's Oncology Group |
2006-07 | PHASE3 |
| NCT00231582 | COMPLETED | Testicular Neoplasms |
Assistance Publique - Hôpitaux de Paris |
2004-09 | PHASE2 |
| NCT00502892 | COMPLETED | Solid Tumors |
M.D. Anderson Cancer Center |
2004-08 | PHASE1 |
| NCT00039195 | COMPLETED | Lymphoma |
Memorial Sloan Kettering Cancer Center |
2006-11 | PHASE2 |
| NCT00292695 | COMPLETED | Lymphoma |
National Health Research Institutes, Taiwan |
2006-05 | PHASE2 |
| NCT00529503 | TERMINATED | Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin |
Seagen Inc. |
2007-09 | PHASE2 |
| NCT00126191 | TERMINATED | Burkitt Lymphoma; Non-Hodgkins Lymphoma; Atypical Burkitt Lymphoma |
Dana-Farber Cancer Institute |
2005-07 | PHASE2 |
| NCT00289809 | COMPLETED | Sarcoma, Soft Tissue |
Istituto Clinico Humanitas |
2006-09 | PHASE1; PHASE2 |
| NCT00842595 | COMPLETED | Diffuse Large B-Cell Lymphoma |
French Innovative Leukemia Organisation |
2003-12 | PHASE2 |
| NCT00607711 | SUSPENDED | Advanced Cancer |
Alaunos Therapeutics |
2008-03 | PHASE1 |
| NCT00267046 | COMPLETED | Sarcoma; Oral Mucositis |
M.D. Anderson Cancer Center |
2005-12 | PHASE2 |
| NCT00541840 | UNKNOWN | Soft Tissue Sarcoma |
Grupo Espanol de Investigacion en Sarcomas |
2007-10 | PHASE1; PHASE2 |
| NCT00002558 | COMPLETED | Extragonadal Germ Cell Tumor; Ovarian Cancer; Testicular Germ Cell Tumor |
Memorial Sloan Kettering Cancer Center |
1994-01 | PHASE1; PHASE2 |
| NCT00622349 | COMPLETED | Carcinoma, Non-Small-Cell Lung |
European Lung Cancer Working Party |
2004-02 | PHASE3 |
| NCT00418535 | COMPLETED | Lymphoma, T-Cell |
Samsung Medical Center |
2006-04 | PHASE2 |
| NCT00047320 | COMPLETED | Brain Tumor; Central Nervous System Tumors; Childhood Germ Cell Tumor |
Children's Oncology Group |
2004-01 | PHASE2 |
| NCT00006455 | COMPLETED | Lymphoma |
Gustave Roussy, Cancer Campus, Grand Paris |
1999-11-26 | PHASE3 |
| NCT00245011 | COMPLETED | Sarcoma |
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins |
2004-10 | PHASE2 |
| NCT00137995 | COMPLETED | Lymphoma, Large-Cell, Diffuse |
Lymphoma Study Association |
2003-06 | PHASE3 |
| NCT00967291 | TERMINATED | Pancreatic Cancer |
IRCCS San Raffaele |
2006-03 | PHASE2 |
| NCT00381940 | COMPLETED | Adult Lymphocyte Depletion Hodgkin Lymphoma; Adult Lymphocyte Predominant Hodgkin Lymphoma; Adult Mixed Cellularity Hodgkin Lymphoma; Adult Nodular Lymphocyte Predominant Hodgkin Lymphoma; Adult Nodular Sclerosis Hodgkin Lymphoma; Childhood Lymphocyte Depletion Hodgkin Lymphoma; Childhood Lymphocyte Predominant Hodgkin Lymphoma; Childhood Mixed Cellularity Hodgkin Lymphoma; Childhood Nodular Lymphocyte Predominant Hodgkin Lymphoma; Childhood Nodular Sclerosis Hodgkin Lymphoma; Recurrent Adult Hodgkin Lymphoma; Recurrent/Refractory Childhood Hodgkin Lymphoma; Stage I Adult Hodgkin Lymphoma; Stage I Childhood Hodgkin Lymphoma; Stage II Adult Hodgkin Lymphoma; Stage II Childhood Hodgkin Lymphoma; Stage III Adult Hodgkin Lymphoma; Stage III Childhood Hodgkin Lymphoma; Stage IV Adult Hodgkin Lymphoma; Stage IV Childhood Hodgkin Lymphoma |
National Cancer Institute (NCI) |
2007-01 | PHASE2 |
| NCT00060944 | COMPLETED | Liposarcoma; Leiomyosarcoma |
Johnson & Johnson Pharmaceutical Research & Development, L.L.C. |
2003-05 | PHASE2 |
| NCT00061893 | COMPLETED | Sarcoma |
Children's Oncology Group |
2004-04 | PHASE2 |
| NCT00636311 | COMPLETED | Hodgkin Disease |
Istituto Clinico Humanitas |
2008-02 | PHASE2 |
| NCT00072280 | TERMINATED | Sarcoma |
Children's Oncology Group |
2004-11 | PHASE2 |
| NCT00163761 | COMPLETED | Non-Hodgkin's Lymphoma; Hodgkin's Disease |
Bayside Health |
2002-12 | PHASE2 |
| NCT00484601 | TERMINATED | Refractory Nasopharyngeal Carcinoma |
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins |
2004-04-15 | PHASE2 |
| NCT00025363 | COMPLETED | Alveolar Childhood Rhabdomyosarcoma; Embryonal Childhood Rhabdomyosarcoma; Embryonal-botryoid Childhood Rhabdomyosarcoma; Previously Treated Childhood Rhabdomyosarcoma; Recurrent Childhood Rhabdomyosarcoma |
National Cancer Institute (NCI) |
2001-11 | PHASE2 |
| NCT00002684 | COMPLETED | Bladder Cancer; Urethral Cancer |
Memorial Sloan Kettering Cancer Center |
1995-05 | PHASE2 |
| NCT00764907 | UNKNOWN | Leukemia |
University Hospital, Motol |
2002-11 | PHASE3 |
| NCT00002546 | COMPLETED | Sarcoma |
Gynecologic Oncology Group |
1993-12 | PHASE3 |
| NCT00093509 | COMPLETED | Sarcoma |
Mark Dewhirst |
1999-11 | PHASE1; PHASE2 |
| NCT00003941 | COMPLETED | Mediastinal Cancer; Metastatic Cancer; Testicular Germ Cell Tumor |
European Organisation for Research and Treatment of Cancer - EORTC |
1999-04 | PHASE3 |
| NCT00058461 | TERMINATED | B-cell Childhood Acute Lymphoblastic Leukemia; Childhood Burkitt Lymphoma; Childhood Diffuse Large Cell Lymphoma; Childhood Immunoblastic Large Cell Lymphoma; L3 Childhood Acute Lymphoblastic Leukemia; Recurrent Childhood Acute Lymphoblastic Leukemia; Recurrent Childhood Large Cell Lymphoma; Recurrent Childhood Lymphoblastic Lymphoma; Recurrent Childhood Small Noncleaved Cell Lymphoma |
National Cancer Institute (NCI) |
2003-11 | PHASE2 |
| NCT00002565 | COMPLETED | Lymphoma |
M.D. Anderson Cancer Center |
1994-05-25 | PHASE3 |
| NCT00187109 | COMPLETED | Germ Cell Tumors; Hepatic Cancer; Neuroblastoma; Osteosarcoma; Rhabdomyosarcoma |
St. Jude Children's Research Hospital |
2000-06 | PHASE1; PHASE2 |
| NCT00003128 | COMPLETED | Sarcoma |
Gynecologic Oncology Group |
1997-11 | PHASE3 |
| NCT00652860 | COMPLETED | Metastatic Cancer; Sarcoma |
Mayo Clinic |
2001-08 | PHASE2 |
| NCT00006373 | COMPLETED | Lymphoma |
H. Lee Moffitt Cancer Center and Research Institute |
2000-02 | PHASE2 |
| NCT00022737 | COMPLETED | Childhood Acute Lymphoblastic Leukemia in Remission; Recurrent Childhood Acute Lymphoblastic Leukemia |
National Cancer Institute (NCI) |
2002-10 | PHASE3 |
| NCT00006734 | COMPLETED | Sarcoma |
Children's Oncology Group |
2001-05 | PHASE3 |
| NCT00003541 | COMPLETED | Lymphoma |
Memorial Sloan Kettering Cancer Center |
1998-06 | PHASE1; PHASE2 |
| NCT00613457 | COMPLETED | Leukemia |
Associazione Italiana Ematologia Oncologia Pediatrica |
2000-09 | PHASE3 |
| NCT00086944 | COMPLETED | Recurrent Adult Diffuse Large Cell Lymphoma; Recurrent Grade 3 Follicular Lymphoma; Recurrent Mantle Cell Lymphoma |
National Cancer Institute (NCI) |
2004-05 | PHASE1; PHASE2 |
| NCT00145639 | COMPLETED | Osteosarcoma |
St. Jude Children's Research Hospital |
1999-05 | PHASE2 |
| NCT00080795 | COMPLETED | Bladder Cancer; Transitional Cell Cancer of the Renal Pelvis and Ureter; Urethral Cancer |
M.D. Anderson Cancer Center |
2001-07 | PHASE2 |
| NCT00283621 | COMPLETED | Sarcoma |
M.D. Anderson Cancer Center |
2003-06-02 | |
| NCT00002641 | COMPLETED | Endometrial Cancer; Kidney Cancer; Ovarian Cancer; Pheochromocytoma; Sarcoma |
European Organisation for Research and Treatment of Cancer - EORTC |
1995-02 | PHASE3 |
| NCT00334867 | WITHDRAWN | Sarcoma |
Children's Oncology Group |
2005-12 | PHASE3 |
| NCT00023998 | COMPLETED | Metastatic Osteosarcoma |
National Cancer Institute (NCI) |
2001-07 | PHASE2 |
| NCT00086970 | TERMINATED | Unspecified Adult Solid Tumor, Protocol Specific |
National Cancer Institute (NCI) |
2004-06 | PHASE1 |
| NCT00002524 | COMPLETED | Lymphoma |
M.D. Anderson Cancer Center |
1993-06 | PHASE2 |
| NCT00002982 | COMPLETED | Lymphoma |
Memorial Sloan Kettering Cancer Center |
1997-01 | PHASE2 |
| NCT00017368 | COMPLETED | Neuroblastoma |
Children's Oncology Group |
2001-04 | PHASE2 |
| NCT00193505 | COMPLETED | Non-Hodgkins Lymphoma |
SCRI Development Innovations, LLC |
2003-10 | PHASE2 |
| NCT00006760 | COMPLETED | Lymphoma |
Children's Oncology Group |
2001-05 | PHASE2 |
| NCT00002466 | COMPLETED | Kidney Cancer; Sarcoma |
Memorial Sloan Kettering Cancer Center |
1990-05 | PHASE2 |
| NCT00072215 | TERMINATED | Extragonadal Germ Cell Tumor; Testicular Germ Cell Tumor |
Alliance for Clinical Trials in Oncology |
2004-04 | PHASE3 |
| NCT00030784 | COMPLETED | Sarcoma |
European Organisation for Research and Treatment of Cancer - EORTC |
2001-11 | PHASE1 |
| NCT00006260 | COMPLETED | Breast Cancer |
Case Comprehensive Cancer Center |
1997-05 | PHASE2 |
| NCT00004186 | COMPLETED | Lung Cancer |
University of Alabama at Birmingham |
1996-12 | PHASE1; PHASE2 |
| NCT00003597 | COMPLETED | Cancer |
Children's Oncology Group |
1998-11 | PHASE1 |
| NCT00003105 | COMPLETED | Bladder Cancer; Transitional Cell Cancer of the Renal Pelvis and Ureter |
Memorial Sloan Kettering Cancer Center |
1997-09 | PHASE1; PHASE2 |
| NCT00007865 | COMPLETED | Lymphoma |
University of Nebraska |
2000-09-01 | PHASE2 |
| NCT00002494 | COMPLETED | Leukemia; Lymphoma |
Alliance for Clinical Trials in Oncology |
1992-05 | PHASE2 |
| NCT00005977 | COMPLETED | Leukemia; Lymphoma |
Children's Oncology Group |
2000-09 | PHASE3 |
| NCT00003937 | COMPLETED | Cardiac Toxicity; Sarcoma |
Children's Oncology Group |
1999-09 | PHASE3 |
| NCT00002835 | COMPLETED | Lymphoma |
M.D. Anderson Cancer Center |
1995-10-30 | PHASE3 |
| NCT00003292 | TERMINATED | Chondrosarcoma; Adult Fibrosarcoma; Adult Leiomyosarcoma; Adult Rhabdomyosarcoma; Adult Malignant Meningioma; Adult Brain Malignant Hemangiopericytoma |
SWOG Cancer Research Network |
1998-07 | PHASE2 |
| NCT00199056 | COMPLETED | Adult Acute Lymphocytic Leukemia |
Goethe University |
1999-10 | PHASE4 |
| NCT00004172 | COMPLETED | Breast Cancer |
Northwestern University |
1999-10 | PHASE2 |
| NCT00002697 | COMPLETED | Lymphoma |
Memorial Sloan Kettering Cancer Center |
1995-09 | PHASE2 |
| NCT00199095 | COMPLETED | Adult Acute Lymphocytic Leukemia |
Goethe University |
1997-02 | PHASE4 |
| NCT00002643 | COMPLETED | Neutropenia; Sarcoma |
National Cancer Institute (NCI) |
1995-04 | PHASE2 |
| NCT00004061 | COMPLETED | Leukemia; Lymphoma; Oral Complications |
Memorial Sloan Kettering Cancer Center |
1999-05 | PHASE2 |
| NCT00002559 | COMPLETED | Ovarian Cancer; Testicular Germ Cell Tumor |
Memorial Sloan Kettering Cancer Center |
1994-01 | PHASE1; PHASE2 |
| NCT00005631 | COMPLETED | Lymphoma |
Memorial Sloan Kettering Cancer Center |
1999-11 | PHASE2 |
| NCT00006708 | TERMINATED | Lymphoma |
SWOG Cancer Research Network |
2000-10 | PHASE3 |
| NCT00002816 | COMPLETED | Leukemia |
Children's Oncology Group |
1996-12 | PHASE3 |
| NCT00004916 | COMPLETED | Lymphoma |
Northwestern University |
1999-02 | PHASE1; PHASE2 |
| NCT00002791 | COMPLETED | Sarcoma |
Radiation Therapy Oncology Group |
1997-02 | PHASE2 |
| NCT00003575 | COMPLETED | Lymphoma |
National Cancer Institute (NCI) |
1999-01 | PHASE2 |
| NCT00002566 | COMPLETED | Extragonadal Germ Cell Tumor; Testicular Germ Cell Tumor |
UNICANCER |
1994-02 | PHASE3 |
| NCT00003212 | COMPLETED | Sarcoma |
European Organisation for Research and Treatment of Cancer - EORTC |
1998-01 | PHASE3 |
| NCT00002974 | COMPLETED | Sarcoma |
University of Wisconsin, Madison |
1996-07 | PHASE2 |
| NCT00187070 | COMPLETED | Lymphoma, Large Cell; Lymphoma, Non-Hodgkin |
St. Jude Children's Research Hospital |
1997-12 | |
| NCT00186849 | COMPLETED | Neuroblastoma |
St. Jude Children's Research Hospital |
1997-10 | PHASE2 |
| NCT00006032 | TERMINATED | Breast Cancer |
H. Lee Moffitt Cancer Center and Research Institute |
2000-03 | PHASE2 |
| NCT00003086 | TERMINATED | Breast Cancer |
Louisiana State University Health Sciences Center Shreveport |
1997-03 | PHASE1; PHASE2 |
| NCT00003683 | COMPLETED | Kidney Cancer |
UNICANCER |
1998-03 | PHASE2 |
| NCT00165139 | COMPLETED | Neuroblastoma; Ewings Sarcoma; Non-rhabdomyosarcoma Soft Tissue Sarcoma |
Dana-Farber Cancer Institute |
1996-01 | PHASE2 |
| NCT00002764 | COMPLETED | Endometrial Cancer; Kidney Cancer; Metastatic Cancer; Ovarian Cancer; Pheochromocytoma; Sarcoma |
European Organisation for Research and Treatment of Cancer - EORTC |
1996-04 | PHASE3 |
| NCT00003657 | COMPLETED | Bladder Cancer; Brain and Central Nervous System Tumors; Carcinoma of Unknown Primary; Extragonadal Germ Cell Tumor; Head and Neck Cancer; Kidney Cancer; Lung Cancer; Ovarian Cancer; Sarcoma; Testicular Germ Cell Tumor; Unspecified Adult Solid Tumor, Protocol Specific |
Dana-Farber Cancer Institute |
1998-07 | PHASE2 |
| NCT00003860 | COMPLETED | Lung Cancer |
UNICANCER |
1998-09 | PHASE2 |
| NCT00002804 | COMPLETED | Sarcoma |
Children's Oncology Group |
1996-09 | PHASE2 |
| NCT00002865 | COMPLETED | Leukemia |
Wake Forest University Health Sciences |
1995-04 | PHASE2 |
| NCT00003198 | COMPLETED | Unspecified Adult Solid Tumor, Protocol Specific |
Memorial Sloan Kettering Cancer Center |
1997-11 | PHASE1 |
| NCT00003776 | COMPLETED | Sarcoma |
Memorial Sloan Kettering Cancer Center |
1998-12 | PHASE2 |
| NCT00003852 | TERMINATED | Childhood Germ Cell Tumor; Extragonadal Germ Cell Tumor; Ovarian Cancer; Testicular Germ Cell Tumor |
UNICANCER |
1998-03 | PHASE2 |
| NCT00003209 | COMPLETED | Cervical Cancer |
European Organisation for Research and Treatment of Cancer - EORTC |
1997-12 | PHASE3 |
| NCT00199069 | COMPLETED | Adult Acute Lymphocytic Leukemia |
Goethe University |
1993-04 | PHASE4 |
| NCT00002526 | COMPLETED | Ovarian Cancer; Sarcoma |
Swiss Cancer Institute |
1993-01 | PHASE2 |
| NCT00645632 | COMPLETED | Sarcoma |
Mayo Clinic |
1990-11 | |
| NCT00003406 | COMPLETED | Chronic Myeloproliferative Disorders; Leukemia; Lymphoma; Multiple Myeloma and Plasma Cell Neoplasm; Myelodysplastic Syndromes; Precancerous/Nonmalignant Condition; Unspecified Adult Solid Tumor, Protocol Specific |
Cancer Treatment Centers of America |
1997-10 | PHASE1; PHASE2 |
| NCT00002802 | COMPLETED | Neuroblastoma |
Children's Hospital Medical Center, Cincinnati |
1990-07 | PHASE3 |
| NCT00003240 | UNKNOWN | Lung Cancer |
National Cancer Institute (NCI) |
1995-10 | PHASE3 |
| NCT00004132 | COMPLETED | Drug/Agent Toxicity by Tissue/Organ; Leukemia; Lymphoma; Multiple Myeloma and Plasma Cell Neoplasm; Oral Complications; Radiation Toxicity |
Jonsson Comprehensive Cancer Center |
2000-01 | PHASE2 |
| NCT00004887 | UNKNOWN | Lung Cancer |
The Christie NHS Foundation Trust |
1999-01 | PHASE3 |
| NCT00280878 | COMPLETED | Non-Hodgkin's Lymphoma (CD20+) |
Bayside Health |
2006-01 | PHASE2 |
| NCT00045461 | UNKNOWN | Fallopian Tube Cancer; Ovarian Cancer; Primary Peritoneal Cavity Cancer |
Ludwig-Maximilians - University of Munich |
2000-06 | PHASE2; PHASE3 |
| NCT00025441 | COMPLETED | Ovarian Cancer; Sarcoma; Small Intestine Cancer |
Societe Internationale d'Oncologie Pediatrique |
1998-11 | PHASE2 |
| NCT00002898 | COMPLETED | Childhood Malignant Fibrous Histiocytoma of Bone; Sarcoma |
Societe Internationale d'Oncologie Pediatrique |
1995-01 | PHASE3 |
| NCT00025064 | UNKNOWN | Lymphoma |
Children's Cancer and Leukaemia Group |
2000-01 | PHASE2 |
| NCT00293358 | COMPLETED | Brain and Central Nervous System Tumors |
Children's Cancer and Leukaemia Group |
1997-01 | PHASE3 |
| NCT00001300 | COMPLETED | Sarcoma |
National Cancer Institute (NCI) |
1992-06 | PHASE3 |
| NCT00002531 | UNKNOWN | Leukemia |
Johann Wolfgang Goethe University Hospital |
1993-01 | PHASE2 |
| NCT00173862 | COMPLETED | Transitional Cell Carcinoma |
National Taiwan University Hospital |
2000-05 | PHASE2 |
| NCT00004086 | UNKNOWN | Leukemia; Lymphoma |
Garden State Cancer Center at the Center for Molecular Medicine and Immunology |
1997-06 | PHASE1 |
| NCT00002822 | COMPLETED | Lung Cancer |
Medical Research Council |
1996-03 | PHASE3 |
| NCT00023738 | COMPLETED | Sarcoma |
Radiation Therapy Oncology Group |
2001-08 | PHASE1; PHASE2 |
| NCT00012311 | UNKNOWN | Breast Cancer |
Herbert Irving Comprehensive Cancer Center |
2000-01 | PHASE2 |
| NCT00003284 | UNKNOWN | Lung Cancer |
Herbert Irving Comprehensive Cancer Center |
1998-01 | PHASE2 |
| NCT00001209 | COMPLETED | Neuroectodermal Tumor, Primitive; Neuroepithelioma; Osteosarcoma; Sarcoma; Sarcoma, Ewing's |
National Cancer Institute (NCI) |
1986-10 | PHASE1 |
| NCT00180908 | COMPLETED | Osteosarcoma; Localised High Grade Osteosarcoma of the Limbs |
Gustave Roussy, Cancer Campus, Grand Paris |
1994-06 | PHASE3 |
| NCT00040690 | COMPLETED | Leukemia; Lymphoma |
Medical Research Council |
2008-11 | PHASE2 |
| NCT00012051 | COMPLETED | Lymphoma |
Commissie Voor Klinisch Toegepast Onderzoek |
2000-09 | PHASE3 |
| NCT00002532 | UNKNOWN | Leukemia |
Hannover Medical School |
1993-01 | PHASE2 |
| NCT00127049 | UNKNOWN | Germ Cell Tumor |
Gustave Roussy, Cancer Campus, Grand Paris |
2004-12 | PHASE2 |
| NCT00026078 | UNKNOWN | Breast Cancer |
Grupo Oncologico Cooperativo del Sur |
2001-03 | PHASE2 |
| NCT00162695 | TERMINATED | Rhabdomyosarcoma; Malignant Soft Tissue |
Gustave Roussy, Cancer Campus, Grand Paris |
1995-07 | PHASE3 |
| NCT00003052 | COMPLETED | Sarcoma |
European Organisation for Research and Treatment of Cancer - EORTC |
1997-07 | PHASE3 |
| NCT00038311 | COMPLETED | Sarcoma |
Pfizer |
2000-09 | PHASE3 |
| NCT00829205 | WITHDRAWN | Lymphoma |
Cancer Research UK |
2009-01 | PHASE1; PHASE2 |
| NCT00689845 | UNKNOWN | Lymphoma |
University Hospital Southampton NHS Foundation Trust |
2007-06 | |
| NCT00148395 | COMPLETED | Non-Small-Cell Lung Carcinoma |
Aktion Bronchialkarzinom e.V. |
2002-06 | PHASE3 |
| NCT00017225 | COMPLETED | Neuroblastoma |
German Society for Pediatric Oncology and Hematology GPOH gGmbH |
1997-05 | PHASE2 |
| NCT00002516 | UNKNOWN | Sarcoma |
University Hospital Muenster |
1992-07 | PHASE3 |
| NCT00204646 | COMPLETED | Sarcoma, Soft Tissue |
University Hospital Tuebingen |
1999-02 | PHASE2 |
| NCT00003159 | COMPLETED | Lung Cancer |
Medical Research Council |
1997-08 | PHASE3 |
| NCT00028860 | COMPLETED | Bladder Cancer; Transitional Cell Cancer of the Renal Pelvis and Ureter |
Tulane University Health Sciences Center |
2001-10 | PHASE2 |
| NCT00011921 | UNKNOWN | Lung Cancer |
EBMT Solid Tumors Working Party |
1997-09 | PHASE3 |
| NCT00004077 | COMPLETED | Testicular Germ Cell Tumor |
Medical Research Council |
1996-05 | PHASE2 |
| NCT00018954 | COMPLETED | Leukemia; Lymphoma |
National Institutes of Health Clinical Center (CC) |
1992-10 | PHASE2 |
| NCT00017160 | WITHDRAWN | Stage III Adult Soft Tissue Sarcoma; Recurrent Adult Soft Tissue Sarcoma; Stage IVA Adult Soft Tissue Sarcoma; Stage IIB Adult Soft Tissue Sarcoma; Stage IIC Adult Soft Tissue Sarcoma |
Radiation Therapy Oncology Group |
PHASE2 | |
| NCT00669812 | UNKNOWN | Lymphoma; Small Intestine Cancer |
Cancer Research UK |
2008-02 | PHASE2 |
| NCT00001270 | COMPLETED | Breast Neoplasms; Lymphoma; Neoplasm Metastasis; Testicular Neoplasms |
National Cancer Institute (NCI) |
1991-06 | PHASE1 |
| NCT00162721 | UNKNOWN | Uterine Sarcoma |
Gustave Roussy, Cancer Campus, Grand Paris |
2001-09 | PHASE3 |
(data from https://clinicaltrials.gov, updated on 2026-08-03)
Check the
Ifosfamide
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Mechanism and Biochemical Profile
Appendix RUO and cGMP Quality Standards
| Quality Dimension | RUO (Research Use Only) | cGMP (Current Good Manufacturing Practice) |
|---|---|---|
| Clinical Applicability | Prohibited in human clinical trials or medical diagnostics. | Mandatory for human clinical trials (Phase I–III) and therapies. |
| Regulatory Status | Non-regulated grade; exempt from drug manufacturing laws. | Legally enforced by health authorities (e.g., FDA, EMA, NMPA). |
| Facility Environment | Unclassified analytical or research laboratories. | Validated Cleanrooms (ISO Class 5–8) with continuous monitoring. |
| Quality Control | Basic purity and activity testing. | Rigorous safety release testing (Sterility, Endotoxin, Mycoplasma). |
| Process Validation | Basic equipment calibration; no process validation required. | Full qualification (IQ/OQ/PQ) and complete batch records. |
| Quality Assurance | Vendor self-declared without required formal QMS. | Mandatory QA/QC unit, Change Control, CAPA, and vendor audits. |
| Regulatory Impact | High risk of IND rejection if used as a critical raw material. | Required for IND/NDA filings, supported by Drug Master Files (DMF). |
Footnotes
Regulatory Note: Governed by FDA (21 CFR Parts 210/211/312), EMA (EudraLex Vol 4), ICH Guidelines (E6/Q7/Q9/Q10), and compendial standards (USP <71>/<85>/<1043>).
Note: Technical data last updated: Sep 1, 2026.