CAS No. 15687-27-1
| IUPAC Name | 2-[4-(2-methylpropyl)phenyl]propanoic acid | |
|---|---|---|
| CAS Number | 15687-27-1 | |
| Molecular Formula |
C13H18O2 |
|
| Molecular Weight (MW) | 206.28 | |
| SMILES | CC(C)CC1=CC=C(C=C1)C(C)C(=O)O | |
| InChIKey | HEFNNWSXXWATRW-UHFFFAOYSA-N |
Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that acts as a non-selective cyclooxygenase inhibitor targeting COX-1 and COX-2. By suppressing cyclooxygenase enzyme activity, Ibuprofen inhibits the conversion of arachidonic acid to pro-inflammatory prostaglandins such as PGE2. This inhibition impairs downstream inflammatory signaling, reduces cellular inflammatory responses, and attenuates prostaglandin-mediated inflammatory mechanisms across various cell types and tissue models. [1]
|
Concentration
Volume
Mass
|
|---|
| Solvent | Solubility & Note |
|---|---|
| DMSO |
41 mg/mL
(198.75 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 41 mg/mL |
| Water | Insoluble |
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
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- Ibuprofen (NSC 256857) Stability
- Ibuprofen (NSC 256857) Molecular Weight
- Ibuprofen (NSC 256857) SMILES
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