Epirubicin hydrochloride has been evaluated across numerous clinical trials spanning Phase 1 safety evaluations to Phase 4 studies, sponsored by academic research centers, university hospitals, and industry entities such as AstraZeneca, with recruitment statuses ranging from active to completed or terminated. Clinical research focuses heavily on breast cancer—including triple-negative carcinoma and stage II/IIIA disease—as well as T-cell non-Hodgkin's lymphoma, esophageal carcinoma, and unspecified solid tumors. Key Phase 2 investigations include pharmacogenetic dosing in combination regimens and preoperative combinations with targeted agents.
| NCT Number | Recruitment | Conditions | Sponsor/Collaborators | Start Date | Phases |
|---|---|---|---|---|---|
| NCT04335669 | ACTIVE_NOT_RECRUITING | Breast Cancer; Triple Negative Breast Neoplasms |
Lund University Hospital |
2019-12-20 | PHASE3 |
| NCT07441460 | RECRUITING | Resectable HER2-positive Breast Cancer |
Shanghai JMT-Bio Inc. |
2026-03-06 | PHASE3 |
| NCT06966700 | RECRUITING | Breast Neoplasms; Triple Negative Breast Neoplasms; HR Low-Positive/HER2-Negative Breast Neoplasms |
Merck Sharp & Dohme LLC |
2025-06-30 | PHASE3 |
| NCT05883852 | RECRUITING | HER2 Positive Early Breast Cancer |
Fudan University |
2023-06-07 | PHASE3 |
| NCT03725059 | ACTIVE_NOT_RECRUITING | Breast Cancer |
Merck Sharp & Dohme LLC |
2018-12-27 | PHASE3 |
| NCT05981014 | RECRUITING | Breast Neoplasms |
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University |
2023-08-01 | PHASE1; PHASE2 |
| NCT07424287 | RECRUITING | NMIBC |
Suzhou Suncadia Biopharmaceuticals Co., Ltd. |
2026-07-13 | PHASE3 |
| NCT06797635 | RECRUITING | Breast Neoplasms; Breast Cancer |
Merck Sharp & Dohme LLC |
2025-03-20 | PHASE2 |
| NCT06291064 | RECRUITING | Triple Negative Breast Cancer |
University of Chicago |
2025-03-18 | PHASE2 |
| NCT06829199 | WITHDRAWN | Early Triple Negative Breast Cancer |
Merck Sharp & Dohme LLC |
2025-03-26 | PHASE2 |
| NCT07256964 | NOT_YET_RECRUITING | TNBC - Triple-Negative Breast Cancer |
Henan Cancer Hospital |
2025-11-26 | PHASE2 |
| NCT06112379 | ACTIVE_NOT_RECRUITING | Breast Cancer |
AstraZeneca |
2023-11-14 | PHASE3 |
| NCT07522879 | RECRUITING | Adenoid Cystic Carcinoma; Sinonasal Carcinoma |
Eye & ENT Hospital of Fudan University |
2026-04-28 | PHASE2 |
| NCT07016399 | RECRUITING | Anatomic Stage II Breast Cancer AJCC v8; Anatomic Stage IIIA Breast Cancer AJCC v8; Triple-Negative Breast Carcinoma |
Vandana Abramson |
2025-09-09 | PHASE2 |
| NCT07753642 | NOT_YET_RECRUITING | Nodal T-follicular Helper Cell Lymphoma |
Sun Yat-sen University |
2026-08-15 | PHASE2 |
| NCT06795503 | NOT_YET_RECRUITING | Triple-negative Breast Cancer |
Fudan University |
2025-02 | PHASE3 |
| NCT07616141 | NOT_YET_RECRUITING | Adenoid Cystic Carcinoma |
Eye & ENT Hospital of Fudan University |
2026-06-01 | PHASE2 |
| NCT03286634 | ACTIVE_NOT_RECRUITING | Down Syndrome; Acute Lymphoblastic Leukemia; Childhood Cancer |
National Hospital Organization Nagoya Medical Center |
2017-04-18 | PHASE2 |
| NCT06860529 | RECRUITING | HR+/HER2- Breast Cancer |
Henan Cancer Hospital |
2025-04-15 | PHASE2 |
| NCT05582499 | RECRUITING | Breast Neoplasm; Breast Cancer; Breast Tumors; Triple-Negative Breast Cancer (TNBC); HER2-positive Breast Cancer; HER2-negative Breast Cancer; Hormone Receptor Positive Tumor; Hormone Receptor Negative Tumor; Early-stage Breast Cancer; Locally Advanced Breast Cancer |
Fudan University |
2022-11-01 | PHASE2 |
| NCT06692491 | NOT_YET_RECRUITING | Rare Tumour |
Peking University Shenzhen Hospital |
2025-01-01 | PHASE2 |
| NCT06964906 | RECRUITING | ER+/HER2- Breast Cancer |
Second Affiliated Hospital, Zhejiang University, School of Medicine |
2025-03-04 | PHASE2 |
| NCT07320508 | RECRUITING | Adenoid Cystic Carcinoma; Sinonasal Carcinoma; Epirubicin |
Eye & ENT Hospital of Fudan University |
2026-01-20 | PHASE2 |
| NCT05678933 | ENROLLING_BY_INVITATION | Peripheral T-cell Lymphoma Targeted Therapy |
Tianjin Medical University Cancer Institute and Hospital |
2023-01-01 | PHASE3 |
| NCT05287308 | NOT_YET_RECRUITING | Breast Cancer |
Chinese Academy of Medical Sciences |
2022-03 | |
| NCT07739485 | RECRUITING | Triple -Negative Breast Cancer |
Liu Shu |
2026-07-30 | PHASE1; PHASE2 |
| NCT05420467 | RECRUITING | Breast Cancer |
Second Affiliated Hospital, Zhejiang University, School of Medicine |
2022-07-10 | PHASE4 |
| NCT05420454 | RECRUITING | Breast Cancer |
Second Affiliated Hospital, Zhejiang University, School of Medicine |
2022-07-10 | PHASE4 |
| NCT06421948 | RECRUITING | Peripheral T-cell Lymphoma |
Yanyan Liu |
2024-05-25 | PHASE1; PHASE2 |
| NCT05900206 | RECRUITING | Breast Cancer |
Karolinska University Hospital |
2023-10-26 | PHASE2 |
| NCT02455141 | ACTIVE_NOT_RECRUITING | Breast Neoplasm |
Shanghai Jiao Tong University School of Medicine |
2016-03 | PHASE3 |
| NCT04771871 | RECRUITING | Triple Negative Breast Cancer |
University College Hospital, Ibadan |
2021-11-29 | PHASE2 |
| NCT01924819 | ACTIVE_NOT_RECRUITING | Gastric Cancer |
Australasian Gastro-Intestinal Trials Group |
2009-09 | PHASE2; PHASE3 |
| NCT05024734 | ACTIVE_NOT_RECRUITING | Bladder Cancer; Non-muscle Invasive |
Roland Seiler-Blarer |
2023-02-21 | PHASE2 |
| NCT05978648 | RECRUITING | Breast Neoplasms |
wang shusen |
2023-09-20 | PHASE2 |
| NCT06699576 | NOT_YET_RECRUITING | Osteosarcoma; Soft Tissue Sarcoma (STS) |
Hansoh BioMedical R&D Company |
2024-12-20 | PHASE1 |
| NCT04290793 | ACTIVE_NOT_RECRUITING | Breast Cancer |
Hebei Medical University Fourth Hospital |
2020-03-01 | PHASE2; PHASE3 |
| NCT06107673 | RECRUITING | Breast Cancer |
Hebei Medical University Fourth Hospital |
2023-09-30 | PHASE2 |
| NCT02897700 | RECRUITING | Breast Cancer |
Shanghai Jiao Tong University School of Medicine |
2013-01 | PHASE1 |
| NCT04138719 | RECRUITING | Breast Cancer; Triple-negative Breast Cancer; Nab-paclitaxel |
Hebei Medical University Fourth Hospital |
2019-11-20 | PHASE2 |
| NCT06140966 | RECRUITING | Multiple Myeloma; Primary Plasma Cell Leukemia; Extramedullary Multiple Myeloma |
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology |
2023-10-20 | PHASE2 |
| NCT06227065 | NOT_YET_RECRUITING | Bladder Cancer; Non-muscle Invasive Bladder Cancer; Low-risk |
University of Bern |
2024-10 | PHASE2 |
| NCT03609047 | ACTIVE_NOT_RECRUITING | Breast Cancer Stage II; Breast Cancer Stage III |
European Organisation for Research and Treatment of Cancer - EORTC |
2019-06-14 | PHASE2 |
| NCT06975644 | NOT_YET_RECRUITING | Triple-Negative Breast Cancer (TNBC); Neoadjuvant Chemotherapy; Chemotherapy Effects |
Zhejiang Provincial People's Hospital |
2025-09-01 | |
| NCT05983094 | NOT_YET_RECRUITING | Breast Cancer; Neoadjuvant Therapy |
Cancer Institute and Hospital, Chinese Academy of Medical Sciences |
2023-09-01 | PHASE2 |
| NCT06121570 | RECRUITING | Breast Neoplasms |
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University |
2023-11-01 | PHASE1 |
| NCT06144944 | ACTIVE_NOT_RECRUITING | Breast Cancer Invasive; Hormone-receptor-positive Breast Cancer; HER2 Low Breast Carcinoma; Early-stage Breast Cancer |
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University |
2024-01-17 | PHASE3 |
| NCT05862064 | RECRUITING | TNBC - Triple-Negative Breast Cancer |
Fudan University |
2023-06-01 | PHASE3 |
| NCT04193059 | ACTIVE_NOT_RECRUITING | Breast Cancer |
Fudan University |
2019-12-20 | PHASE3 |
| NCT02535221 | RECRUITING | Breast Cancer |
Peking University |
2015-07-29 | PHASE3 |
| NCT06470633 | NOT_YET_RECRUITING | Breast Cancer; HR+/HER2- Breast Cancer |
The First Affiliated Hospital with Nanjing Medical University |
2024-08-01 | PHASE2 |
| NCT05901428 | RECRUITING | Hormone Receptor Positive HER-2 Negative Breast Cancer |
Fudan University |
2023-06-01 | PHASE3 |
| NCT04872985 | ACTIVE_NOT_RECRUITING | Breast Cancer; Hormone-receptor Positive Breast Cancer |
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University |
2021-04-20 | PHASE2 |
| NCT04067037 | ACTIVE_NOT_RECRUITING | Classical Hodgkin Lymphoma |
Henan Cancer Hospital |
2019-08-26 | PHASE2 |
| NCT04437160 | RECRUITING | Triple Negative Breast Cancer |
Chinese Academy of Medical Sciences |
2020-02-01 | PHASE2 |
| NCT06500208 | RECRUITING | Breast Cancer |
Shanghai Jiao Tong University School of Medicine |
2024-11-01 | PHASE2 |
| NCT06227117 | RECRUITING | Breast Cancer |
RemeGen Co., Ltd. |
2023-07-27 | PHASE2 |
| NCT04136782 | RECRUITING | Breast Cancer |
Shengjing Hospital |
2021-07-19 | PHASE4 |
| NCT04137640 | UNKNOWN | Breast Cancer |
Shengjing Hospital |
2021-07-19 | PHASE4 |
| NCT06404463 | NOT_YET_RECRUITING | Early Breast Cancer; Neoadjuvant Therapy; HR+HER2- Breast Cancer |
Fudan University |
2024-05-06 | PHASE2 |
| NCT03036488 | COMPLETED | Triple Negative Breast Neoplasms |
Merck Sharp & Dohme LLC |
2017-03-07 | PHASE3 |
| NCT04947059 | RECRUITING | Bladder Cancer |
University of Thessaly |
2021-12-14 | PHASE3 |
| NCT02627248 | UNKNOWN | Breast Cancer |
Shandong University |
2015-10 | PHASE4 |
| NCT05296317 | COMPLETED | Localized Breast Cancer |
Centre Georges Francois Leclerc |
2022-09-02 | |
| NCT06513364 | COMPLETED | Breast Cancer |
Beijing Wehand-Bio Pharmaceutical Co., Ltd |
2024-09-10 | PHASE2 |
| NCT04433156 | COMPLETED | Marginal Zone Lymphoma |
Henan Cancer Hospital |
2020-04-22 | PHASE2 |
| NCT06389006 | RECRUITING | Breast Cancer |
RemeGen Co., Ltd. |
2024-04-29 | PHASE2 |
| NCT05834582 | UNKNOWN | TNBC - Triple-Negative Breast Cancer |
The First Affiliated Hospital with Nanjing Medical University |
2023-04-08 | PHASE2 |
| NCT06766266 | RECRUITING | Non-Muscle Invasive Bladder Urothelial Carcinoma |
First Affiliated Hospital of Chongqing Medical University |
2025-01-10 | PHASE1 |
| NCT06009627 | COMPLETED | Breast Cancer |
Tianjin Medical University Cancer Institute and Hospital |
2023-04-11 | PHASE2; PHASE3 |
| NCT04296175 | ACTIVE_NOT_RECRUITING | Triple-negative Breast Cancer |
Fudan University |
2020-03-05 | PHASE3 |
| NCT04736394 | UNKNOWN | Non-muscle Invasive Bladder Cancer |
Jiangsu Yahong Meditech Co., Ltd aka Asieris |
2021-09-29 | PHASE3 |
| NCT04668365 | SUSPENDED | Diffuse Large B Cell Lymphoma; CD79A Gene Mutation; CD79B Gene Mutation |
Henan Cancer Hospital |
2020-12-25 | PHASE2 |
| NCT05816694 | UNKNOWN | Histological or Cytological Confirmed Stage Ⅲ and Ⅳa Thymoma |
Peng Liu |
2023-04-30 | PHASE2 |
| NCT05033808 | UNKNOWN | Sepsis |
Jena University Hospital |
2022-10-19 | PHASE2 |
| NCT05656079 | UNKNOWN | Breast Cancer |
Shanghai Pudong Hospital |
2021-07-01 | |
| NCT00301925 | UNKNOWN | Breast Cancer |
Institute of Cancer Research, United Kingdom |
2005-12-16 | PHASE3 |
| NCT03355157 | COMPLETED | Metastatic Breast Cancer |
GBG Forschungs GmbH |
2018-03-01 | PHASE4 |
| NCT05887726 | UNKNOWN | Diffuse Large B Cell Lymphoma |
Liaoning Cancer Hospital & Institute |
2023-08-01 | PHASE2 |
| NCT03277924 | COMPLETED | Soft Tissue Sarcoma; Bone Sarcoma |
Grupo Espanol de Investigacion en Sarcomas |
2017-05-31 | PHASE1; PHASE2 |
| NCT01710176 | COMPLETED | Localized High-risk Soft Tissue Sarcomas of the Extremities and Trunk Wall in Adults |
Italian Sarcoma Group |
2011-06-01 | PHASE3 |
| NCT05472896 | UNKNOWN | Hepatocellular Carcinoma |
Gao-jun Teng |
2022-06-09 | PHASE3 |
| NCT06470464 | COMPLETED | Germ Cell Tumor; Yolk Sac Tumor |
Shandong First Medical University |
2021-11-11 | PHASE2 |
| NCT05914753 | UNKNOWN | Breast Cancer; Chemotherapy Effect |
Zhejiang Provincial People's Hospital |
2023-07-01 | |
| NCT05121350 | UNKNOWN | Soft Tissue Sarcoma |
Chia Tai Tianqing Pharmaceutical Group Co., Ltd. |
2022-03 | PHASE3 |
| NCT05681728 | UNKNOWN | Breast Cancer |
Cancer Institute and Hospital, Chinese Academy of Medical Sciences |
2022-02-01 | PHASE2 |
| NCT03876886 | UNKNOWN | Triple Negative Breast Cancer |
Chinese Academy of Medical Sciences |
2019-02-22 | PHASE3 |
| NCT04214626 | COMPLETED | Diffuse Large B Cell Lymphoma |
Henan Cancer Hospital |
2020-01-05 | PHASE2 |
| NCT05871918 | UNKNOWN | HER-2 Positive Breast Cancer |
Tianjin Medical University Cancer Institute and Hospital |
2022-10-08 | PHASE3 |
| NCT05447702 | RECRUITING | Triple Negative Breast Cancer |
West China Hospital |
2022-11-01 | PHASE2 |
| NCT05491694 | UNKNOWN | Breast Cancer; TNBC - Triple-Negative Breast Cancer |
The First Affiliated Hospital with Nanjing Medical University |
2022-09-01 | PHASE2 |
| NCT02641847 | ACTIVE_NOT_RECRUITING | Triple Negative Breast Cancer; Breast Cancer |
Fudan University |
2016-01 | PHASE2; PHASE3 |
| NCT04809779 | UNKNOWN | Triple Negative Breast Cancer |
First Affiliated Hospital, Sun Yat-Sen University |
2021-03 | PHASE2 |
| NCT05084586 | UNKNOWN | Bladder Cancer; Epirubicin Adverse Reaction; Superficial Bladder Cancer; Tumor Recurrence |
Ankara Training and Research Hospital |
2019-10-01 | |
| NCT05165225 | ACTIVE_NOT_RECRUITING | Breast Cancer; HER2-low-expressing Breast Cancer; Hormone Receptor-positive Breast Cancer; Neoadjuvant Therapy |
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University |
2021-07-13 | PHASE2 |
| NCT04172259 | ACTIVE_NOT_RECRUITING | Breast Cancer; Neoadjuvant Chemotherapy |
Sun Yat-sen University |
2019-01-10 | PHASE2 |
| NCT04877821 | COMPLETED | Triple Negative Breast Cancer |
Guangdong Provincial People's Hospital |
2021-09-15 | PHASE2 |
| NCT03498716 | TERMINATED | Triple Negative Breast Cancer |
Hoffmann-La Roche |
2018-08-02 | PHASE3 |
| NCT01404156 | COMPLETED | Esophageal Cancer; Adenocarcinoma, Esophageal; Adenocarcinoma, Gastroesophageal Junction |
Dr. Gordon Buduhan |
2015-09 | PHASE2; PHASE3 |
| NCT04770272 | TERMINATED | Triple-negative Breast Cancer |
Palleos Healthcare GmbH |
2021-03-01 | PHASE2 |
| NCT05483439 | UNKNOWN | Stage II-III Breast Cancer |
Shengjing Hospital |
2021-10-20 | PHASE2 |
| NCT04576143 | RECRUITING | HER2-negative Breast Cancer; Neoadjuvant Chemotherapy |
Second Affiliated Hospital, Zhejiang University, School of Medicine |
2020-09-20 | PHASE2; PHASE3 |
| NCT04717531 | UNKNOWN | Breast Cancer |
The First Affiliated Hospital with Nanjing Medical University |
2021-06-03 | PHASE2 |
| NCT04899570 | UNKNOWN | Intravascular Large B-Cell Lymphoma |
Peking Union Medical College Hospital |
2021-04-01 | PHASE2 |
| NCT05474690 | WITHDRAWN | Breast Cancer; HER2-positive Breast Cancer |
Henan Cancer Hospital |
2022-05-11 | PHASE3 |
| NCT05251766 | UNKNOWN | Breast Cancer; Chemotherapy Effect |
Xuli Meng |
2022-04-20 | PHASE1 |
| NCT05146635 | UNKNOWN | Bladder Cancer |
Mansoura University |
2021-12-01 | |
| NCT02897050 | SUSPENDED | Breast Cancer |
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University |
2016-09 | PHASE2 |
| NCT03356860 | COMPLETED | Breast Cancer; Triple Negative Breast Cancer; Luminal B |
Grand Hôpital de Charleroi |
2017-04-13 | PHASE1; PHASE2 |
| NCT00773695 | COMPLETED | Breast Cancer |
Hoffmann-La Roche |
2008-11-07 | PHASE2 |
| NCT04738188 | UNKNOWN | Hepatocellular Carcinoma |
Beijing Tsinghua Chang Gung Hospital |
2020-03-18 | |
| NCT01210768 | UNKNOWN | Breast Cancer |
TTY Biopharm |
2010-06 | PHASE2 |
| NCT02752815 | UNKNOWN | Diffuse Large B-cell Lymphoma |
Ruijin Hospital |
2016-06-14 | PHASE4 |
| NCT05053386 | UNKNOWN | Hepatocellular Carcinoma |
Zhejiang Cancer Hospital |
2021-10 | |
| NCT04418154 | UNKNOWN | Triple Negative Breast Cancer |
Fudan University |
2020-06-09 | PHASE2 |
| NCT04094896 | UNKNOWN | HER2-Positive Breast Cancer |
Guangdong Provincial People's Hospital |
2019-09-17 | PHASE2 |
| NCT04301739 | NOT_YET_RECRUITING | Triple Negative Breast Cancer |
Shanghai Henlius Biotech |
2020-04-17 | PHASE3 |
| NCT05204524 | UNKNOWN | Leiomyosarcoma |
Chinese Academy of Medical Sciences |
2021-08-27 | |
| NCT01726452 | COMPLETED | Adenocarcinoma of the Oesophagus; Adenocarcinoma of the Oesophago-gastric Junction; Oesophageal Tumours; Junctional Tumours; Oesophageal Cancer |
Cancer Trials Ireland |
2013-01-24 | PHASE3 |
| NCT05253066 | UNKNOWN | Breast Neoplasms |
Shengjing Hospital |
2022-02-25 | PHASE2; PHASE3 |
| NCT04490993 | UNKNOWN | Non-muscle Invasive Bladder Cancer |
Jiangsu Yahong Meditech Co., Ltd aka Asieris |
2017-03-30 | PHASE3 |
| NCT03123770 | UNKNOWN | Breast Cancer |
Zhejiang University |
2016-12 | PHASE4 |
| NCT04498793 | UNKNOWN | HER2-negative Breast Cancer |
Cancer Institute and Hospital, Chinese Academy of Medical Sciences |
2020-09 | PHASE2 |
| NCT05128617 | Completed | Breast Cancer |
Institut de cancérologie Strasbourg Europe|Université de Strasbourg - Unité de Recherche 3072 - Mitochondries Stress oxydant Protection musculaire |
2021-11-04 | -- |
| NCT03025477 | RECRUITING | Ovarian Cancer, Epithelial |
Groupe Hospitalier Diaconesses Croix Saint-Simon |
2016-10 | PHASE2 |
| NCT01779050 | TERMINATED | Breast Neoplasms |
Washington University School of Medicine |
2013-12-19 | PHASE2 |
| NCT04676997 | UNKNOWN | Triple Negative Breast Cancer |
Shandong Cancer Hospital and Institute |
2020-05-20 | PHASE2 |
| NCT03894007 | TERMINATED | Early-stage Breast Cancer; HER2-positive Breast Cancer |
Renske Altena |
2019-05-23 | PHASE2 |
| NCT04067102 | WITHDRAWN | Triple Negative Breast Cancer |
Hebei Medical University Fourth Hospital |
2019-05-10 | |
| NCT02395640 | COMPLETED | Gastric Cancer |
Fudan University |
2015-03 | PHASE3 |
| NCT02315196 | ACTIVE_NOT_RECRUITING | Estrogen Receptor-negative Breast Cancer; HER2-negative Breast Cancer; Progesterone Receptor-negative Breast Cancer; Stage IIA Breast Cancer; Stage IIB Breast Cancer; Stage IIIA Breast Cancer; Stage IIIB Breast Cancer; Stage IIIC Breast Cancer; Triple-negative Breast Cancer |
Rutgers, The State University of New Jersey |
2015-02-25 | PHASE2 |
| NCT04213898 | UNKNOWN | Triple-negative Breast Cancer |
Henan Cancer Hospital |
2020-01 | PHASE1; PHASE2 |
| NCT02767674 | UNKNOWN | Diffuse Large B Cell Lymphoma |
The First Affiliated Hospital with Nanjing Medical University |
2016-05 | PHASE3 |
| NCT03556358 | COMPLETED | Breast Cancer; Breast Neoplasms; HER2-positive Breast Cancer; Stage II Breast Cancer; Stage IIIA Breast Cancer |
Tanvex BioPharma USA, Inc. |
2018-06-28 | PHASE3 |
| NCT01593020 | COMPLETED | Breast Cancer |
M.D. Anderson Cancer Center |
2012-08-03 | PHASE2 |
| NCT02971345 | UNKNOWN | Hepatocellular Carcinoma; Portal Vein Tumor Thrombus |
Shanghai Zhongshan Hospital |
2017-01 | PHASE3 |
| NCT03647280 | UNKNOWN | Breast Cancer |
Zhejiang Cancer Hospital |
2018-12-01 | |
| NCT03289819 | COMPLETED | Malignant Neoplasm of Breast |
Institut fuer Frauengesundheit |
2018-03-23 | PHASE2 |
| NCT02287129 | COMPLETED | Adenocarcinoma of the Esophagogastric Junction |
Technical University of Munich |
2014-12-05 | PHASE2 |
| NCT01907529 | UNKNOWN | Stage III Breast Cancer |
Hebei Medical University Fourth Hospital |
2019-08 | PHASE2; PHASE3 |
| NCT03272477 | COMPLETED | Breast Neoplasms |
Palleos Healthcare GmbH |
2017-10-05 | PHASE2 |
| NCT03168061 | UNKNOWN | Solid Tumor; Soft Tissue Sarcoma; Metastatic Sarcoma; Sarcoma |
NanoCarrier Co., Ltd. |
2017-06-30 | PHASE1; PHASE2 |
| NCT02624973 | ACTIVE_NOT_RECRUITING | Breast Cancer |
Haukeland University Hospital |
2016-04-15 | PHASE2 |
| NCT02879513 | UNKNOWN | Invasive Ductal Breast Cancer; Tubular Breast Cancer; Mucinous Breast Cancer; Inflammatory Breast Cancer |
RenJi Hospital |
2014-01 | PHASE3 |
| NCT01929811 | TERMINATED | pCR Rate; BCT Rate; Safety |
Shanghai Jiao Tong University School of Medicine |
2013-10 | PHASE2 |
| NCT04659551 | COMPLETED | Breast Cancer |
Istituto Oncologico Veneto IRCCS |
2017-10-05 | PHASE2 |
| NCT02742051 | COMPLETED | Breast Cancer |
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University |
2016-06 | PHASE2 |
| NCT02987244 | UNKNOWN | T Cell Non-Hodgkin's Lymphoma |
Peking Union Medical College Hospital |
2016-03 | PHASE1; PHASE2 |
| NCT02549677 | COMPLETED | Breast Neoplasms |
Ruijin Hospital |
2015-10 | PHASE4 |
| NCT02842099 | UNKNOWN | Breast Cancer |
Peking Union Medical College Hospital |
2014-01 | PHASE2 |
| NCT03154749 | COMPLETED | Triple-Negative Breast Cancer |
Guangdong Provincial People's Hospital |
2016-09-01 | PHASE2 |
| NCT02682693 | COMPLETED | Breast Cancer Female NOS; Tubular Breast Cancer Stage II; Mucinous Breast Cancer Stage II; Invasive Ductal Breast Cancer; HER2 Positive Breast Cancer; Inflammatory Breast Cancer; Tubular Breast Cancer Stage III |
GBG Forschungs GmbH |
2017-02-13 | PHASE2 |
| NCT03815474 | UNKNOWN | Sarcoma, Soft Tissue |
Liaoning Cancer Hospital & Institute |
2019-05-20 | PHASE2 |
| NCT03373708 | UNKNOWN | Breast Cancer; Chemotherapy; Endocrine Breast Diseases |
Zhiyong Yu |
2017-12-20 | PHASE2; PHASE3 |
| NCT03756090 | UNKNOWN | Breast Cancer; Breast Diseases; Breast Neoplasms |
Zhejiang Cancer Hospital |
2018-12-01 | |
| NCT01642771 | UNKNOWN | Breast Cancer |
China Breast Cancer Clinical Study Group |
2012-06 | PHASE3 |
| NCT03799679 | UNKNOWN | Triple Negative Breast Cancer |
Fudan University |
2018-11-26 | PHASE4 |
| NCT03507465 | UNKNOWN | Breast Cancer |
Guangdong Provincial People's Hospital |
2017-11-29 | PHASE2; PHASE3 |
| NCT01966471 | COMPLETED | Breast Cancer |
Hoffmann-La Roche |
2014-01-31 | PHASE3 |
| NCT03349177 | UNKNOWN | Breast Cancer; Pathological Complete Response; Neoadjuvant Chemotherapy |
Zhiyong Yu |
2017-11-27 | PHASE2; PHASE3 |
| NCT03140553 | COMPLETED | HER2-Positive Breast Cancer |
Guangdong Provincial People's Hospital |
2016-09-01 | PHASE2 |
| NCT03755115 | UNKNOWN | Small Cell Lung Cancer Extensive Stage |
Henan Cancer Hospital |
2019-02-01 | PHASE2 |
| NCT01779206 | COMPLETED | Breast Cancer |
Women's Cancer Study Group GmbH |
2012-05 | PHASE2; PHASE3 |
| NCT02177552 | UNKNOWN | Esophageal Neoplasms; Stomach Neoplasms |
Rigshospitalet, Denmark |
2014-06 | PHASE2 |
| NCT03273595 | UNKNOWN | Neoplasms, Breast |
Xijing Hospital |
2016-07 | PHASE2 |
| NCT03113955 | COMPLETED | Localized Hepatocellular Carcinoma |
Varian Medical Systems |
2017-10-24 | |
| NCT03013504 | COMPLETED | HER2 Positive Breast Cancer |
Prestige Biopharma Limited |
2018-02-19 | PHASE3 |
| NCT02789332 | COMPLETED | Breast Cancer; Triple Negative Breast Neoplasms; HRpos Breast Neoplasms; BRCA 1 /2 and / or HRD |
GBG Forschungs GmbH |
2016-09 | PHASE2 |
| NCT02628613 | COMPLETED | Breast Cancer |
Fudan University |
2015-12 | PHASE2 |
| NCT01630083 | COMPLETED | CLDN18.2-positive Adenocarcinoma of the Gastroesophageal Junction; CLDN18.2-positive Adenocarcinoma of Esophagus; CLDN18.2-positive Gastric Adenocarcinoma |
Astellas Pharma Global Development, Inc. |
2012-07-19 | PHASE2 |
| NCT02909751 | COMPLETED | Breast Cancer |
Vejle Hospital |
2016-09-14 | PHASE2 |
| NCT02949258 | UNKNOWN | Stomach Neoplasms; Gastric Cancer |
Jinling Hospital, China |
2017-01 | PHASE2 |
| NCT00907543 | COMPLETED | Esophageal Neoplasms |
Richard Malthaner |
2009-04 | |
| NCT02076594 | TERMINATED | Locally Advanced Unresectable Gastric Cancer; Metastatic Gastric Cancer |
Gruppo Italiano per lo studio dei Carcinomi dell'Apparato Digerente |
2013-01 | PHASE3 |
| NCT02631499 | UNKNOWN | Carcinoma, Hepatocellular; Neoplastic Cells, Circulating |
Fudan University |
2015-12 | PHASE4 |
| NCT00407186 | UNKNOWN | Gastric Cancer |
Dutch Colorectal Cancer Group |
2007-01-11 | PHASE3 |
| NCT02760953 | UNKNOWN | Urinary Bladder Neoplasms |
Huashan Hospital |
2017-10-19 | |
| NCT01690702 | COMPLETED | Breast Cancer |
GBG Forschungs GmbH |
2012-09 | PHASE3 |
| NCT02871869 | UNKNOWN | Diffuse, Large B-Cell, Lymphoma |
Xinjiang Medical University |
2016-09 | PHASE2; PHASE3 |
| NCT01855828 | COMPLETED | Her2-Positive Breast Cancer |
Yale University |
2013-09 | PHASE2 |
| NCT02115152 | UNKNOWN | Stage II Breast Cancer; Stage III Breast Cancer |
Guangxi Medical University |
2014-06 | PHASE2 |
| NCT02050919 | COMPLETED | Pleomorphic Rhabdomyosarcoma; Stage IIB Adult Soft Tissue Sarcoma AJCC v7; Stage III Adult Soft Tissue Sarcoma AJCC v7; Stage IV Adult Soft Tissue Sarcoma AJCC v7 |
OHSU Knight Cancer Institute |
2013-12-03 | PHASE2 |
| NCT02438865 | COMPLETED | Neoplasm, Ureter; Neoplasm, Bladder |
Mansoura University |
2015-01-01 | PHASE2 |
| NCT01503905 | UNKNOWN | Breast Cancer Nos Premenopausal |
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University |
2011-12 | |
| NCT01134523 | UNKNOWN | Breast Cancer |
Chinese Academy of Medical Sciences |
2010-05 | PHASE3 |
| NCT02685059 | COMPLETED | Breast Cancer |
GBG Forschungs GmbH |
2016-06 | PHASE2 |
| NCT02400567 | COMPLETED | Neoadjuvant Operable Breast Cancer |
UNICANCER |
2015-01 | PHASE2 |
| NCT00450203 | UNKNOWN | Oesophagogastric Cancer |
Professor David Cunningham |
2007-10 | PHASE2; PHASE3 |
| NCT02694224 | UNKNOWN | Breast Cancer |
Clinica Universidad de Navarra, Universidad de Navarra |
2016-04 | PHASE2 |
| NCT03022123 | UNKNOWN | Diffuse Large B-cell Lymphoma |
Hebei Medical University Fourth Hospital |
2016-11 | |
| NCT01936064 | UNKNOWN | Haematological Abnormality |
Lagos State University |
2016-10 | PHASE1; PHASE2 |
| NCT03151044 | UNKNOWN | Diffuse Large B-cell Lymphoma |
FENG Ji-feng |
2016-07 | PHASE3 |
| NCT01314833 | COMPLETED | Primary Breast Cancer |
Fudan University |
2010-06-01 | PHASE3 |
| NCT04127019 | COMPLETED | Primary Breast Cancer |
Fudan University |
2010-06-01 | PHASE3 |
| NCT00630032 | COMPLETED | Breast Cancer |
UNICANCER |
2007-09 | PHASE3 |
| NCT02214602 | COMPLETED | Carcinoma of Urinary Bladder, Superficial |
Mansoura University |
2014-07 | PHASE4 |
| NCT01150630 | COMPLETED | Pancreatic Cancer |
IRCCS San Raffaele |
2010-05 | PHASE2 |
| NCT01049425 | COMPLETED | Primary Breast Cancer; Her2 Non-overexpressing |
Women's Cancer Study Group GmbH |
2009-02-05 | PHASE3 |
| NCT01216644 | COMPLETED | Gastric Cancer |
Krankenhaus Nordwest |
2010-08 | PHASE2; PHASE3 |
| NCT02638857 | UNKNOWN | Recurrence Hepatocellular Carcinoma; Advanced Hepatocellular Carcinoma |
Second Military Medical University |
2015-09 | PHASE1; PHASE2 |
| NCT02980965 | COMPLETED | Breast Cancer Female |
Fudan University |
2013-05 | PHASE3 |
| NCT01358877 | COMPLETED | Breast Cancer |
Hoffmann-La Roche |
2011-11-08 | PHASE3 |
| NCT02041338 | UNKNOWN | Breast Cancer; Neoadjuvant Chemotherapy |
Chinese Academy of Medical Sciences |
2014-01 | PHASE2 |
| NCT02510781 | UNKNOWN | Breast Neoplasms |
Hospital Affiliated to Military Medical Science, Beijing |
2015-01 | PHASE2 |
| NCT02207361 | UNKNOWN | Metastatic Breast Cancer |
Tianjin Medical University Cancer Institute and Hospital |
2013-12 | PHASE4 |
| NCT02125344 | COMPLETED | Tubular Breast Cancer Stage II; Tubular Breast Cancer Stage III; Mucinous Breast Cancer Stage II; Breast Cancer Female NOS; Invasive Ductal Breast Cancer; HER2 Positive Breast Cancer; Inflammatory Breast Cancer |
GBG Forschungs GmbH |
2014-12 | PHASE3 |
| NCT01690325 | TERMINATED | Breast Cancer |
Women's Cancer Study Group GmbH |
2012-09 | PHASE2 |
| NCT02365805 | COMPLETED | Breast Cancer |
Fundación Pública Andaluza para la gestión de la Investigación en Sevilla |
2014-04 | PHASE2 |
| NCT01234324 | COMPLETED | Stomach Neoplasms; Gastroesophageal Junction Neoplasms |
AIO-Studien-gGmbH |
2010-10 | PHASE2 |
| NCT04224922 | COMPLETED | Breast Cancer |
Universitair Ziekenhuis Brussel |
2015-05 | PHASE2 |
| NCT02755311 | UNKNOWN | Hepatocellular Carcinoma |
Sun Yat-sen University |
2014-03 | PHASE3 |
| NCT00496795 | UNKNOWN | Stage III Breast Cancer AJCC V7 |
University of Bergen |
2007-09 | PHASE2 |
| NCT01216111 | COMPLETED | Triple Negative Breast Cancer |
Fudan University |
2011-01-01 | PHASE3 |
| NCT04031703 | COMPLETED | Breast Cancer |
Fudan University |
2011-01-01 | PHASE3 |
| NCT00798070 | ACTIVE_NOT_RECRUITING | Breast Cancer |
Karolinska University Hospital |
2007-02 | PHASE3 |
| NCT02132949 | COMPLETED | Breast Cancer |
Hoffmann-La Roche |
2014-07-14 | PHASE2 |
| NCT00379015 | COMPLETED | Breast Cancer |
Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan |
2006-01 | PHASE2 |
| NCT01036087 | COMPLETED | Breast Cancer |
M.D. Anderson Cancer Center |
2010-11 | PHASE2 |
| NCT01026116 | COMPLETED | Breast Neoplasms |
Fudan University |
2009-12 | PHASE3 |
| NCT01150513 | COMPLETED | Breast Cancer |
Chinese Academy of Medical Sciences |
2009-06 | PHASE2; PHASE3 |
| NCT01870791 | TERMINATED | Esophageal Neoplasm; Gastric Neoplasm |
University Hospitals, Leicester |
2012-05 | PHASE2 |
| NCT01624025 | COMPLETED | Metastatic Advanced Gastric Cancer |
Yonsei University |
2012-06 | PHASE2 |
| NCT01830244 | UNKNOWN | Breast Cancer |
Barwon Health |
2013-04 | PHASE2 |
| NCT02867397 | COMPLETED | Patients With Advanced or Metastatic Solid Tumors |
Disphar International B.V. |
2012-01 | PHASE1 |
| NCT02005783 | COMPLETED | Grade 3/4 Neutropenia; Febrile Neutropenia |
Shanghai Jiao Tong University School of Medicine |
2013-10 | PHASE2 |
| NCT01740271 | UNKNOWN | Breast Neoplasms |
AHS Cancer Control Alberta |
2012-12 | PHASE2 |
| NCT00820547 | COMPLETED | Breast Cancer |
UNICANCER |
2009-01 | PHASE2 |
| NCT01830270 | TERMINATED | Stomach Neoplasms; Oesophageal Junction Cancer; Lower Oesophagus Cancer |
Centre Hospitalier Universitaire de Besancon |
2011-05 | PHASE2 |
| NCT01985841 | TERMINATED | Breast Cancer |
Hellenic Oncology Research Group |
2011-10 | PHASE2 |
| NCT00737438 | COMPLETED | Esophageal Cancer; Gastric Cancer |
Memorial Sloan Kettering Cancer Center |
2008-08 | PHASE2 |
| NCT01167738 | TERMINATED | Pancreatic Cancer |
IRCCS San Raffaele |
2010-07 | PHASE2 |
| NCT01479036 | UNKNOWN | Breast Cancer |
Xijing Hospital |
2011-10 | PHASE3 |
| NCT00776724 | COMPLETED | Breast Cancer; Chemotherapy |
National Taiwan University Hospital |
2008-05-29 | PHASE3 |
| NCT01220128 | TERMINATED | Neoplasms, Breast |
GlaxoSmithKline |
2011-04-11 | PHASE2 |
| NCT01697072 | TERMINATED | Gastric Cancer |
Amgen |
2012-10 | PHASE3 |
| NCT00593697 | COMPLETED | Breast Neoplasms |
Finnish Breast Cancer Group |
2008-01 | PHASE3 |
| NCT00425516 | COMPLETED | Individualized Chemotherapy |
Centre Jean Perrin |
2007-01 | PHASE2 |
| NCT01386346 | COMPLETED | Esophageal Cancer; Malignant Neoplasm of Cardio-esophageal Junction of Stomach |
Weill Medical College of Cornell University |
2011-06 | PHASE1 |
| NCT01428414 | UNKNOWN | HER-2 Positive Breast Cancer |
Zhimin Shao |
2011-08 | PHASE2 |
| NCT01964027 | UNKNOWN | Stage IV Gastric Cancer With Metastasis |
Anhui Medical University |
2013-10 | PHASE2 |
| NCT01199432 | COMPLETED | Breast Cancer |
Tao OUYANG |
2010-10 | PHASE4 |
| NCT00196872 | COMPLETED | Breast Cancer |
GBG Forschungs GmbH |
2004-07 | PHASE3 |
| NCT01594177 | COMPLETED | Unilateral HER2 Positive Breast Cancer |
GBG Forschungs GmbH |
2012-05 | PHASE2 |
| NCT00087178 | COMPLETED | Breast Cancer |
NSABP Foundation Inc |
2004-05 | PHASE3 |
| NCT00014222 | COMPLETED | Breast Cancer |
NCIC Clinical Trials Group |
2000-12-04 | PHASE3 |
| NCT01327521 | WITHDRAWN | Carcinoma, Hepatocellular |
Albert Koong |
2011-02 | PHASE3 |
| NCT01204437 | COMPLETED | Breast Cancer |
GBG Forschungs GmbH |
2009-03 | PHASE2; PHASE3 |
| NCT00658580 | COMPLETED | Small Cell Lung Carcinoma, Extensive Disease |
European Lung Cancer Working Party |
2000-04 | PHASE3 |
| NCT01053390 | COMPLETED | Gallbladder Neoplasms |
Shanghai Jiao Tong University School of Medicine |
2009-10 | PHASE3 |
| NCT01985724 | COMPLETED | Breast Cancer |
Hellenic Oncology Research Group |
2007-10 | PHASE3 |
| NCT01094964 | UNKNOWN | Bladder Cancer |
Cancer Research Campaign Clinical Trials Centre |
2009-10 | PHASE3 |
| NCT01849380 | UNKNOWN | Breast Neoplasms; Neoadjuvant Therapy |
Shandong University |
2013-06 | PHASE4 |
| NCT00756470 | TERMINATED | Breast Cancer |
M.D. Anderson Cancer Center |
2008-10 | PHASE2 |
| NCT01624441 | COMPLETED | Estrogen Receptor Negative; HER2/Neu Negative; Male Breast Carcinoma; Progesterone Receptor Negative; Recurrent Breast Carcinoma; Stage IV Breast Cancer AJCC v6 and v7; Triple-Negative Breast Carcinoma |
National Cancer Institute (NCI) |
2012-08-21 | PHASE1 |
| NCT01880385 | UNKNOWN | Inflammatory Breast Cancer |
Association Tunisienne de lutte Contre le Cancer |
2011-03 | PHASE1 |
| NCT02225652 | COMPLETED | Women With Primary Breast Cancer |
Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS |
2010-09 | PHASE2 |
| NCT01123473 | TERMINATED | Adenocarcinoma of the Gastroesophageal Junction; Gastric Cancer |
European Organisation for Research and Treatment of Cancer - EORTC |
2010-12 | PHASE2 |
| NCT00424606 | COMPLETED | Breast Cancer |
Hellenic Oncology Research Group |
2001-06 | PHASE3 |
| NCT00129935 | COMPLETED | Breast Cancer |
Spanish Breast Cancer Research Group |
2004-02 | PHASE3 |
| NCT00625898 | TERMINATED | Breast Cancer |
NSABP Foundation Inc |
2008-04 | PHASE3 |
| NCT06309732 | COMPLETED | Testicular Neoplasms |
Queen Mary University of London |
2006-07 | PHASE2 |
| NCT00878904 | COMPLETED | Unspecified Adult Solid Tumor, Protocol Specific |
University of California, San Francisco |
2009-09-13 | PHASE1 |
| NCT01378533 | UNKNOWN | Breast Cancer |
Chinese Academy of Medical Sciences |
2011-05 | PHASE3 |
| NCT01301040 | TERMINATED | Breast Cancer |
Jules Bordet Institute |
2011-03 | PHASE2 |
| NCT00824785 | TERMINATED | Oesophago-gastric Cancer |
Royal Marsden NHS Foundation Trust |
2008-05 | PHASE3 |
| NCT00689156 | COMPLETED | Breast Neoplasms |
Danish Breast Cancer Cooperative Group |
2008-06 | PHASE3 |
| NCT01641406 | UNKNOWN | Infiltrating Duct and Lobular Carcinoma In Situ; Invasive Lobular Breast Carcinoma; Inflammatory Breast Carcinoma |
Auxilio Mutuo Cancer Center |
2011-03 | PHASE2 |
| NCT01740271 | Recruiting | Breast Neoplasms |
AHS Cancer Control Alberta |
2012-12 | Phase 2 |
| NCT02324088 | COMPLETED | Inflammatory Breast Cancer |
UNICANCER |
2000-10 | PHASE3 |
| NCT00843934 | UNKNOWN | Carcinoma, Hepatocellular |
Nihon University |
2009-03 | PHASE2; PHASE3 |
| NCT01558947 | UNKNOWN | Gastric Cancer |
Zhejiang Cancer Hospital |
2011-01 | PHASE2 |
| NCT01710592 | COMPLETED | Gastro Oesophageal Cancer |
Cancer Trials Ireland |
2007-05 | PHASE2 |
| NCT00248703 | COMPLETED | Breast Cancer |
Oslo University Hospital |
2003-10 | PHASE2 |
| NCT00544505 | UNKNOWN | Breast Cancer |
King Faisal Specialist Hospital & Research Center |
2007-09 | |
| NCT00822848 | COMPLETED | Sarcoma |
OHSU Knight Cancer Institute |
2009-02 | PHASE1 |
| NCT00767377 | COMPLETED | Gastric Cancer |
Fudan University |
2007-05 | PHASE2 |
| NCT01276769 | UNKNOWN | Triple Negative Breast Cancer |
Chinese Academy of Medical Sciences |
2008-01 | PHASE2 |
| NCT00722293 | COMPLETED | Neoplasms, Breast |
GlaxoSmithKline |
2008-07-08 | PHASE1 |
| NCT00055679 | COMPLETED | Breast Cancer |
UNICANCER |
2002-08 | PHASE3 |
| NCT00431795 | TERMINATED | Breast Cancer |
Hellenic Oncology Research Group |
2003-06 | PHASE2 |
| NCT00052910 | COMPLETED | Esophageal Cancer; Gastric Cancer |
Alliance for Clinical Trials in Oncology |
2002-12 | PHASE3 |
| NCT00513292 | COMPLETED | HER2/Neu Positive; Stage IA Breast Cancer; Stage IB Breast Cancer; Stage II Breast Cancer; Stage IIIA Breast Cancer |
National Cancer Institute (NCI) |
2007-07 | PHASE3 |
| NCT00615602 | COMPLETED | Breast Cancer |
Hellenic Oncology Research Group |
2004-10 | PHASE3 |
| NCT00912444 | TERMINATED | Breast Cancer |
Shanghai Jiao Tong University School of Medicine |
2009-07 | PHASE3 |
| NCT02450058 | COMPLETED | Breast Cancer; Chemotherapy, Adjuvant |
IRCCS Azienda Ospedaliera Universitaria San Martino - IST Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy |
1996-11 | PHASE3 |
| NCT00499603 | UNKNOWN | Breast Cancer |
M.D. Anderson Cancer Center |
2007-07 | PHASE2 |
| NCT01093235 | UNKNOWN | Breast Cancer; Cardiac Toxicity; Perioperative/Postoperative Complications |
Cambridge University Hospitals NHS Foundation Trust |
2009-04 | PHASE3 |
| NCT00601705 | COMPLETED | Esophageal Cancer; Gastric Cancer |
Case Comprehensive Cancer Center |
2008-01-05 | PHASE2 |
| NCT00123318 | COMPLETED | Gastric Cancer |
Trans Tasman Radiation Oncology Group |
2003-02 | PHASE3 |
| NCT00047099 | COMPLETED | Breast Cancer |
Ludwig-Maximilians - University of Munich |
2001-08 | PHASE3 |
| NCT02846428 | COMPLETED | Breast Cancer |
Hoffmann-La Roche |
2004-03 | PHASE2 |
| NCT00841828 | COMPLETED | Breast Cancer |
Spanish Breast Cancer Research Group |
2009-02 | PHASE2 |
| NCT00957125 | UNKNOWN | Breast Cancer |
Thomas Hatschek |
2008-09 | PHASE2 |
| NCT00933517 | COMPLETED | Pathological Response Rate |
Centre Jean Perrin |
2009-09 | PHASE2 |
| NCT00548899 | COMPLETED | Breast Cancer |
GBG Forschungs GmbH |
2007-11 | PHASE2 |
| NCT00567554 | COMPLETED | Breast Cancer |
GBG Forschungs GmbH |
2007-10 | PHASE3 |
| NCT00270894 | COMPLETED | Breast Neoplasm |
Accelerated Community Oncology Research Network |
2005-11 | PHASE2 |
| NCT00002784 | COMPLETED | Breast Cancer |
ETOP IBCSG Partners Foundation |
1996-06 | PHASE3 |
| NCT00950300 | COMPLETED | Breast Cancer |
Hoffmann-La Roche |
2009-10-16 | PHASE3 |
| NCT00954512 | TERMINATED | Neoplasms |
Merck Sharp & Dohme LLC |
2009-09-25 | PHASE1; PHASE2 |
| NCT00667420 | TERMINATED | Esophageal Adenocarcinoma; Gastric Adenocarcinoma |
Massachusetts General Hospital |
2008-04 | PHASE1; PHASE2 |
| NCT01205217 | WITHDRAWN | Neoplasms, Breast |
GlaxoSmithKline |
2010-12 | PHASE2 |
| NCT00629278 | UNKNOWN | Breast Cancer |
Azienda Ospedaliero-Universitaria di Modena |
2007-12 | PHASE3 |
| NCT01031030 | UNKNOWN | Breast Cancer |
Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS |
1997-11 | PHASE3 |
| NCT00595972 | COMPLETED | Gastric Cancer |
Fudan University |
2007-11 | PHASE2 |
| NCT00719550 | COMPLETED | Esophagogastric Junction Adenocarcinoma; Gastric Cancer; Esophageal Cancer |
Amgen |
2009-02 | PHASE1; PHASE2 |
| NCT00432172 | COMPLETED | Breast Cancer |
Spanish Breast Cancer Research Group |
2007-04-24 | PHASE2 |
| NCT00002529 | COMPLETED | Breast Cancer |
ETOP IBCSG Partners Foundation |
1993-05 | PHASE3 |
| NCT00454636 | COMPLETED | Gastric Cancer |
Hoffmann-La Roche |
2007-03 | PHASE2 |
| NCT00705315 | COMPLETED | Breast Cancer |
Hellenic Oncology Research Group |
2008-05 | PHASE1; PHASE2 |
| NCT00755976 | COMPLETED | Melanoma (Skin) |
Cancer Trials Ireland |
2007-08 | PHASE2 |
| NCT00963729 | COMPLETED | Breast Cancer |
Imperial College London |
2008-09 | PHASE3 |
| NCT00066443 | COMPLETED | Breast Cancer |
NCIC Clinical Trials Group |
2003-11-03 | PHASE1; PHASE2 |
| NCT00486356 | COMPLETED | Extrahepatic Bile Duct Cancer; Gallbladder Cancer; Gastric Cancer; Liver Cancer; Unspecified Adult Solid Tumor, Protocol Specific |
University of Nebraska |
2004-10-01 | PHASE1 |
| NCT00525759 | COMPLETED | Breast Cancer |
Sheffield Teaching Hospitals NHS Foundation Trust |
2007-07 | PHASE2 |
| NCT00231582 | COMPLETED | Testicular Neoplasms |
Assistance Publique - Hôpitaux de Paris |
2004-09 | PHASE2 |
| NCT00604435 | COMPLETED | Breast Cancer |
Xijing Hospital |
2008-02 | PHASE2 |
| NCT01869192 | COMPLETED | Malignant Neoplasm of Female Breast |
University of Colorado, Denver |
2003-03-05 | PHASE2 |
| NCT00464646 | COMPLETED | Breast Cancer |
NSABP Foundation Inc |
2007-05 | PHASE2 |
| NCT00820053 | COMPLETED | Hepatocellular Carcinoma |
Eastern Hepatobiliary Surgery Hospital |
2009-01 | PHASE2 |
| NCT00309556 | COMPLETED | Breast Cancer |
Austrian Breast & Colorectal Cancer Study Group |
2005-02 | PHASE3 |
| NCT00176488 | TERMINATED | Breast Cancer |
University of Medicine and Dentistry of New Jersey |
2003-06 | PHASE2 |
| NCT00743964 | COMPLETED | Advanced Gastric Cancer |
Samsung Medical Center |
2008-04 | PHASE2 |
| NCT00540800 | COMPLETED | Breast Cancer |
National Cancer Institute, Naples |
2004-02 | PHASE3 |
| NCT00201396 | COMPLETED | Nasopharyngeal Carcinoma |
National Health Research Institutes, Taiwan |
2003-08 | PHASE3 |
| NCT00960284 | COMPLETED | Pancreatic Cancer |
IRCCS San Raffaele |
2003-06 | PHASE2; PHASE3 |
| NCT00054587 | COMPLETED | Breast Cancer |
UNICANCER |
2001-06 | PHASE3 |
| NCT00872625 | COMPLETED | Breast Cancer |
Centre Antoine Lacassagne |
2007-04 | PHASE1 |
| NCT02307227 | COMPLETED | Breast Neoplasms |
Centro di Riferimento Oncologico - Aviano |
2006-04 | PHASE2 |
| NCT00966706 | COMPLETED | Pancreatic Cancer |
IRCCS San Raffaele |
2005-06 | PHASE2 |
| NCT02392845 | COMPLETED | Metastatic Breast Cancer |
Hospices Civils de Lyon |
2005-06 | PHASE1 |
| NCT00322374 | COMPLETED | Metastatic Breast Cancer |
R-Pharm |
2006-08 | PHASE1 |
| NCT01222052 | UNKNOWN | Breast Cancer |
Martin-Luther-Universität Halle-Wittenberg |
2002-01 | PHASE3 |
| NCT00162812 | TERMINATED | Breast Cancer |
Jules Bordet Institute |
2003-01 | PHASE2 |
| NCT00753207 | COMPLETED | Breast Cancer |
Cancer Trials Ireland |
2007-10 | PHASE1 |
| NCT00193206 | COMPLETED | Breast Cancer |
SCRI Development Innovations, LLC |
2005-09 | PHASE2 |
| NCT00527449 | COMPLETED | Primary Breast Cancer |
Klinikum Weissenfels |
2006-05 | PHASE2 |
| NCT00531973 | UNKNOWN | Breast Cancer |
Catholic University, Italy |
2007-01 | PHASE4 |
| NCT00215644 | COMPLETED | Esophageal Cancer; Gastric Cancer |
Merck KGaA, Darmstadt, Germany |
2005-08-31 | PHASE2 |
| NCT00246103 | COMPLETED | Neoplasms, Advanced |
H. Lee Moffitt Cancer Center and Research Institute |
2004-03 | PHASE1 |
| NCT00193050 | COMPLETED | Breast Cancer |
SCRI Development Innovations, LLC |
2001-11 | PHASE2 |
| NCT00311636 | COMPLETED | Breast Cancer |
Gruppo Italiano Mammella (GIM) |
2003-09 | PHASE3 |
| NCT00429871 | COMPLETED | Breast Cancer |
Hellenic Oncology Research Group |
2002-05 | PHASE3 |
| NCT00431080 | COMPLETED | Breast Cancer |
Hellenic Oncology Research Group |
2004-08 | PHASE3 |
| NCT00070278 | UNKNOWN | Breast Cancer |
Cambridge University Hospitals NHS Foundation Trust |
2005-01 | PHASE3 |
| NCT00336791 | COMPLETED | Breast Cancer |
M.D. Anderson Cancer Center |
2003-09 | PHASE3 |
| NCT00242203 | COMPLETED | Breast Neoplasms |
Washington University School of Medicine |
2002-10 | PHASE2 |
| NCT00239343 | COMPLETED | Breast Cancer |
AstraZeneca |
2004-10 | PHASE2 |
| NCT00002542 | COMPLETED | Breast Cancer |
NCIC Clinical Trials Group |
1993-07-20 | PHASE3 |
| NCT00057980 | COMPLETED | Liver Cancer |
Northwestern University |
2002-10 | PHASE1; PHASE2 |
| NCT00375999 | COMPLETED | Stomach Neoplasms |
Yonsei University |
2006-09 | PHASE2 |
| NCT00110695 | COMPLETED | Breast Neoplasms |
NSABP Foundation Inc |
2005-04 | PHASE2 |
| NCT00017095 | COMPLETED | Breast Cancer |
European Organisation for Research and Treatment of Cancer - EORTC |
2001-03 | PHASE3 |
| NCT00072319 | COMPLETED | Breast Cancer |
Memorial Sloan Kettering Cancer Center |
2003-08 | PHASE2 |
| NCT00096304 | TERMINATED | Prostate Cancer |
Medical University of South Carolina |
2004-06-08 | PHASE1 |
| NCT00544232 | COMPLETED | Breast Cancer |
GBG Forschungs GmbH |
2002-08 | PHASE3 |
| NCT00140075 | COMPLETED | Adenocarcinoma |
Pfizer |
2000-11 | PHASE3 |
| NCT01433614 | COMPLETED | Metastatic Breast Cancer |
Thomas Hatschek |
2002-12 | PHASE3 |
| NCT00433420 | ACTIVE_NOT_RECRUITING | Breast Cancer |
IRCCS Azienda Ospedaliera Universitaria San Martino - IST Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy |
2003-04 | PHASE3 |
| NCT00645866 | COMPLETED | Breast Cancer |
Mayo Clinic |
2003-04 | PHASE2 |
| NCT01148446 | COMPLETED | Elderly Patients (>65 Years); Diffuse Large B Cell Lymphoma (DLBCL) |
Fondazione Italiana Linfomi - ETS |
2003-01 | PHASE3 |
| NCT00364754 | COMPLETED | Metastatic/Recurrent Breast Cancer |
YM BioSciences |
2004-05 | PHASE1 |
| NCT00129922 | COMPLETED | Breast Cancer |
Spanish Breast Cancer Research Group |
1999-11 | PHASE3 |
| NCT00795899 | COMPLETED | Breast Cancer |
GBG Forschungs GmbH |
2002-01 | PHASE2 |
| NCT00253500 | COMPLETED | Breast Cancer |
Case Comprehensive Cancer Center |
2002-06 | PHASE2 |
| NCT02115204 | COMPLETED | Breast Cancer |
Women's Cancer Study Group GmbH |
2000-06 | PHASE3 |
| NCT00062296 | COMPLETED | Leukemia; Lymphoma |
Fox Chase Cancer Center |
2003-03 | PHASE2 |
| NCT00002866 | COMPLETED | Breast Cancer; Neutropenia |
NCIC Clinical Trials Group |
1996-08-12 | PHASE1 |
| NCT00154739 | COMPLETED | Non-Small Cell Lung Cancer |
National Taiwan University Hospital |
1998-10 | PHASE2 |
| NCT00617370 | COMPLETED | Breast Cancer; Adenocarcinoma of the Breast |
Memorial Sloan Kettering Cancer Center |
2004-11 | |
| NCT00668616 | COMPLETED | Breast Cancer |
North Eastern German Society of Gynaecological Oncology |
2000-03 | PHASE3 |
| NCT00620100 | TERMINATED | Breast Neoplasms |
Sanofi |
2004-09 | PHASE2 |
| NCT00146588 | COMPLETED | Breast Cancer; Stage I Breast Cancer; Stage II Breast Cancer; Stage IIIA Breast Cancer |
Craig A. Bunnell, MD, MPH |
2002-04 | |
| NCT00038402 | COMPLETED | Breast Cancer |
M.D. Anderson Cancer Center |
2001-04 | PHASE3 |
| NCT00020748 | COMPLETED | Unspecified Adult Solid Tumor, Protocol Specific |
Georgetown University |
2000-08 | PHASE1 |
| NCT00017186 | COMPLETED | Malignant Mesothelioma |
Alliance for Clinical Trials in Oncology |
2001-07 | PHASE2 |
| NCT00005584 | ACTIVE_NOT_RECRUITING | Lymphoma |
European Organisation for Research and Treatment of Cancer - EORTC |
1998-10 | PHASE3 |
| NCT00053911 | TERMINATED | Breast Cancer |
UNICANCER |
2002-11 | PHASE3 |
| NCT00215514 | COMPLETED | Stomach Cancer; Gastric Cancer; Gastro-esophageal Junction Cancer |
Dana-Farber Cancer Institute |
2000-09 | EARLY_PHASE1 |
| NCT00193024 | TERMINATED | Breast Cancer |
SCRI Development Innovations, LLC |
2001-09 | PHASE2 |
| NCT03888677 | COMPLETED | Breast Cancer |
Henrik Lindman |
2001-02 | PHASE3 |
| NCT00004873 | COMPLETED | Gastric Cancer |
Swiss Cancer Institute |
1999-08 | PHASE2 |
| NCT00002870 | COMPLETED | Breast Cancer |
UNICANCER |
1994-12 | PHASE3 |
| NCT00008034 | COMPLETED | Breast Cancer |
European Organisation for Research and Treatment of Cancer - EORTC |
2000-02 | PHASE1 |
| NCT00309569 | COMPLETED | Early Stage Breast Cancer |
Austrian Breast & Colorectal Cancer Study Group |
1991-10 | PHASE3 |
| NCT00003852 | TERMINATED | Childhood Germ Cell Tumor; Extragonadal Germ Cell Tumor; Ovarian Cancer; Testicular Germ Cell Tumor |
UNICANCER |
1998-03 | PHASE2 |
| NCT00003606 | COMPLETED | Lung Cancer |
UNICANCER |
1996-03 | PHASE3 |
| NCT00162695 | TERMINATED | Rhabdomyosarcoma; Malignant Soft Tissue |
Gustave Roussy, Cancer Campus, Grand Paris |
1995-07 | PHASE3 |
| NCT00002544 | COMPLETED | Breast Cancer |
Arbeitsgemeinschaft fur Internistische Onkologie |
1993-05 | PHASE3 |
| NCT00378313 | COMPLETED | Stage IIB Breast Cancer; Stage IIIA Breast Cancer; Stage IIIB Breast Cancer; Stage IV Breast Cancer; Breast Cancer; Locally Advanced |
NSABP Foundation Inc |
2001-11 | PHASE2 |
| NCT00003262 | UNKNOWN | Lymphoma |
Centro di Riferimento Oncologico - Aviano |
1997-05 | PHASE2 |
| NCT00004934 | COMPLETED | Fallopian Tube Cancer; Ovarian Cancer; Primary Peritoneal Cavity Cancer |
Nordic Society of Gynaecological Oncology - Clinical Trials Unit |
1999-08 | PHASE3 |
| NCT00002615 | COMPLETED | Gastric Cancer |
Medical Research Council |
1994-06 | PHASE3 |
| NCT00114816 | COMPLETED | Breast Cancer |
Finnish Breast Cancer Group |
2004-01 | PHASE3 |
| NCT00005581 | UNKNOWN | Breast Cancer |
IRCCS Azienda Ospedaliera Universitaria San Martino - IST Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy |
2000-06 | PHASE3 |
| NCT00130936 | TERMINATED | Gastric Cancer; Esophageal Cancer; Tumors |
AHS Cancer Control Alberta |
2005-10 | PHASE1; PHASE2 |
| NCT00309920 | UNKNOWN | Breast Cancer |
Heinrich-Heine University, Duesseldorf |
2004-01 | |
| NCT00011921 | UNKNOWN | Lung Cancer |
EBMT Solid Tumors Working Party |
1997-09 | PHASE3 |
| NCT00220129 | COMPLETED | Oesophageal Carcinoma |
Royal Marsden NHS Foundation Trust |
2002-11 | PHASE2 |
| NCT00097383 | COMPLETED | Breast Cancer |
Eli Lilly and Company |
PHASE1; PHASE2 | |
| NCT00262210 | COMPLETED | Non-Hodgkin's Lymphoma |
National Health Research Institutes, Taiwan |
1995-06 | PHASE2 |
| NCT00516425 | UNKNOWN | Breast Cancer |
Charing Cross Hospital |
2007-01 | PHASE3 |
| NCT00669812 | UNKNOWN | Lymphoma; Small Intestine Cancer |
Cancer Research UK |
2008-02 | PHASE2 |
| NCT00010140 | UNKNOWN | Breast Cancer |
International Collaborative Cancer Group |
1997-08 | PHASE3 |
| NCT00033683 | UNKNOWN | Breast Cancer |
Institute of Cancer Research, United Kingdom |
2001-02 | PHASE2 |
| NCT00022178 | UNKNOWN | Carcinoma of Unknown Primary |
The Christie NHS Foundation Trust |
1998-12 | PHASE3 |
| NCT00288002 | COMPLETED | Breast Cancer |
GBG Forschungs GmbH |
2005-01 | PHASE3 |
| NCT00525642 | UNKNOWN | Breast Neoplasms; Adjuvant; Chemotherapy |
Fudan University |
2003-06 | PHASE2; PHASE3 |
| NCT00556127 | COMPLETED | Diffuse Large B-Cell Lymphoma; POOR PROGNOSIS |
Gruppo Italiano Multiregionale per lo studio dei Linfomi e delle Leucemie |
2002-06 | PHASE2 |
| NCT00003577 | COMPLETED | Breast Cancer |
University Hospital Birmingham |
1996-03 | PHASE3 |
| NCT00286819 | COMPLETED | Breast Cancer |
Central European Cooperative Oncology Group |
2005-04 | PHASE2 |
| NCT00025441 | COMPLETED | Ovarian Cancer; Sarcoma; Small Intestine Cancer |
Societe Internationale d'Oncologie Pediatrique |
1998-11 | PHASE2 |
| NCT00002953 | COMPLETED | Breast Cancer |
Medical Research Council |
1996-12 | PHASE3 |
| NCT00002898 | COMPLETED | Childhood Malignant Fibrous Histiocytoma of Bone; Sarcoma |
Societe Internationale d'Oncologie Pediatrique |
1995-01 | PHASE3 |
| NCT00198172 | TERMINATED | Germ Cell Tumor |
Indiana University |
2000-10 | PHASE2 |
| NCT00003012 | COMPLETED | Breast Cancer |
Scottish Cancer Therapy Network |
1996-10 | PHASE3 |
| NCT00220103 | COMPLETED | Adenocarcinoma of Oesophagus |
Royal Marsden NHS Foundation Trust |
2002-11 | PHASE2 |
| NCT00075465 | UNKNOWN | Gastric Cancer |
GERCOR - Multidisciplinary Oncology Cooperative Group |
2001-04 | PHASE2 |
| NCT00398489 | UNKNOWN | Breast Cancer |
Technical University of Munich |
2006-10 | PHASE2 |
| NCT00041262 | UNKNOWN | Esophageal Cancer |
Medical Research Council |
2004-11 | PHASE3 |
| NCT00099281 | TERMINATED | Breast Cancer; Metastases |
YM BioSciences |
2004-05 | PHASE3 |
| NCT00218205 | UNKNOWN | Prostate Cancer |
Department of Veterans Affairs, New Jersey |
2002-07 | PHASE2 |
| NCT00005583 | COMPLETED | Endometrial Cancer |
Nordic Society of Gynaecological Oncology - Clinical Trials Unit |
2000-01 | PHASE3 |
| NCT00039546 | UNKNOWN | Breast Cancer |
Cancer Research Campaign Clinical Trials Centre |
2001-08 | PHASE3 |
| NCT01351038 | TERMINATED | KRAS Wild Type; Resectable Type II Gastric Adenocarcinoma |
Arbeitsgemeinschaft medikamentoese Tumortherapie |
PHASE2 | |
| NCT00004237 | COMPLETED | Breast Cancer |
Royal Marsden NHS Foundation Trust |
1998-10 | PHASE2 |
| NCT00256360 | COMPLETED | Breast Cancer |
Universitaire Ziekenhuizen KU Leuven |
2005-09 | PHASE2 |
| NCT00058487 | COMPLETED | Liver Cancer |
Dana-Farber Cancer Institute |
2001-12 | PHASE2 |
| NCT00021047 | COMPLETED | Esophageal Cancer; Extrahepatic Bile Duct Cancer; Gastric Cancer; Head and Neck Cancer; Liver Cancer; Unspecified Adult Solid Tumor, Protocol Specific |
National Institutes of Health Clinical Center (CC) |
2001-07 | PHASE1; PHASE2 |
| NCT00343356 | COMPLETED | Bladder Neoplasms |
LanZhou University |
1996-06 | PHASE2 |
| NCT01159236 | WITHDRAWN | Breast Cancer |
M.D. Anderson Cancer Center |
2010-09 | |
| NCT00003893 | COMPLETED | Breast Cancer |
University Hospital Birmingham |
1998-07 | PHASE3 |
(data from https://clinicaltrials.gov, updated on 2025-09-12)
Check the
Epirubicin HCl
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Mechanism and Biochemical Profile
Appendix RUO and cGMP Quality Standards
| Quality Dimension | RUO (Research Use Only) | cGMP (Current Good Manufacturing Practice) |
|---|---|---|
| Clinical Applicability | Prohibited in human clinical trials or medical diagnostics. | Mandatory for human clinical trials (Phase I–III) and therapies. |
| Regulatory Status | Non-regulated grade; exempt from drug manufacturing laws. | Legally enforced by health authorities (e.g., FDA, EMA, NMPA). |
| Facility Environment | Unclassified analytical or research laboratories. | Validated Cleanrooms (ISO Class 5–8) with continuous monitoring. |
| Quality Control | Basic purity and activity testing. | Rigorous safety release testing (Sterility, Endotoxin, Mycoplasma). |
| Process Validation | Basic equipment calibration; no process validation required. | Full qualification (IQ/OQ/PQ) and complete batch records. |
| Quality Assurance | Vendor self-declared without required formal QMS. | Mandatory QA/QC unit, Change Control, CAPA, and vendor audits. |
| Regulatory Impact | High risk of IND rejection if used as a critical raw material. | Required for IND/NDA filings, supported by Drug Master Files (DMF). |
Footnotes
Regulatory Note: Governed by FDA (21 CFR Parts 210/211/312), EMA (EudraLex Vol 4), ICH Guidelines (E6/Q7/Q9/Q10), and compendial standards (USP <71>/<85>/<1043>).
Note: Technical data last updated: Sep 1, 2026.