CAS No. 73963-72-1

Batch: Purity:99.99
Cilostazol Chemical Structure
Chemical Structure
Check the Cilostazol product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name 6-[4-(1-cyclohexyltetrazol-5-yl)butoxy]-3,4-dihydro-1H-quinolin-2-one
CAS Number 73963-72-1
Molecular Formula

C20H27N5O2

Molecular Weight (MW) 369.46
SMILES C1CCC(CC1)N2C(=NN=N2)CCCCOC3=CC4=C(C=C3)NC(=O)CC4
InChIKey RRGUKTPIGVIEKM-UHFFFAOYSA-N

Ordering Information

Biological Activity

Cilostazol is a potent cyclic nucleotide phosphodiesterase type 3 (PDE3) inhibitor that also inhibits adenosine uptake. By selectively blocking PDE3, it increases intracellular cyclic AMP (cAMP) levels, leading to the inhibition of platelet aggregation and promotion of arterial vasodilation. These downstream effects result in dilated peripheral blood vessels and reduced platelet coagulation. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 74 mg/mL (200.29 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 6 mg/mL
Water Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.