2D Structure
loading...
2D chemical structural formula diagram.
3D Structure
loading...
This 3D model represents a theoretically simulated conformation and is for reference only.
Check the
Axitinib (AG-013736)
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | N-methyl-2-[[3-[(E)-2-pyridin-2-ylethenyl]-1H-indazol-6-yl]sulfanyl]benzamide | |
|---|---|---|
| CAS Number | 319460-85-0 | |
| Molecular Formula |
C22H18N4OS |
|
| Molecular Weight (MW) | 386.47 | |
| SMILES | CNC(=O)C1=CC=CC=C1SC2=CC3=C(C=C2)C(=NN3)C=CC4=CC=CC=N4 | |
| InChIKey | RITAVMQDGBJQJZ-FMIVXFBMSA-N |
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
26 mg/mL
(67.27 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
40 mg/mL
(103.5 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
77 mg/mL
(199.23 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
26 mg/mL
(67.27 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
41 mg/mL
(106.08 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
- Axitinib (AG-013736) Mechanism of Action: VEGFR Inhibition in Tumor Endothelial Cells Research
- Axitinib (AG-013736) Clinical Trials
- Axitinib (AG-013736): Selectivity & Specificity
- Axitinib (AG-013736) Working Concentration | Cell Culture | Treatment
- Axitinib (AG-013736) Solubility in DMSO
- Axitinib (AG-013736) Stock Solution
- Axitinib (AG-013736) Storage
- Axitinib (AG-013736) Stability
- Axitinib (AG-013736) Combination Database
- Axitinib (AG-013736) Molecular Weight
- Axitinib (AG-013736) SMILES
- Axitinib (AG-013736) CAS Number
- Axitinib (AG-013736) IC50 for Cell-based and Cell-free Assays
- Axitinib (AG-013736) APExBIO (A8370)? Try a better option.
- Axitinib (AG-013736) Cayman (13813)? Try a better option.
- Axitinib (AG-013736) MedChemExpress (HY-10065)? Try a better option.
- Axitinib (AG-013736) Sigma (AMBH2D6ED301)? Try a better option.
- Axitinib (AG-013736) SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.