CAS No. 54965-21-8

Batch: Purity:99.88
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Albendazole Chemical Structure
Chemical Structure
Check the Albendazole product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name methyl N-(6-propylsulfanyl-1H-benzimidazol-2-yl)carbamate
CAS Number 54965-21-8
Molecular Formula

C12H15N3O2S
Molecular Weight (MW) 265.33
SMILES CCCSC1=CC2=C(C=C1)N=C(N2)NC(=O)OC
InChIKey HXHWSAZORRCQMX-UHFFFAOYSA-N

Ordering Information

Biological Activity

Albendazole is a benzimidazole anthelmintic agent that functions as a tubulin inhibitor by binding to the colchicine-sensitive site on tubulin and blocking microtubule polymerization. Disruption of cytoplasmic microtubule assembly impairs cellular glucose uptake and depletes intracellular glycogen stores, resulting in structural degeneration of parasitic tegument and intestinal cells and inhibition of parasite viability. [1]

How to Prepare Stock Solution?

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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 17 mg/mL (64.07 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water Insoluble
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.