Molecular Weight: 220.22 g/mol

5-hydroxytryptophan (5-HTP) Chemical Structure
Chemical Structure
Check the 5-hydroxytryptophan (5-HTP) product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 44 mg/mL (199.8 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water 7 mg/mL
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

Aliquotting Service

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Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.

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Chemical Information

IUPAC Name 2-amino-3-(5-hydroxy-1H-indol-3-yl)propanoic acid
CAS Number 56-69-9
Molecular Formula

C11H12N2O3
Molecular Weight (MW) 220.22
SMILES C1=CC2=C(C=C1O)C(=CN2)CC(C(=O)O)N
InChIKey LDCYZAJDBXYCGN-UHFFFAOYSA-N

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Note: Technical data last updated: Sep 1, 2026.