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4-Hydroxytamoxifen is a potent, selective ER antagonist. It blocks ER signaling by binding ER, inhibiting tumor growth.
4-Hydroxytamoxifen (Afimoxifene): Mechanism of Action
4-Hydroxytamoxifen (Afimoxifene) MOA：Targeting Estrogen Receptor/Cre-loxP Signaling Pathway for Conditional Gene Editing and Transgenic Models
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