CAS No. 56-12-2
| IUPAC Name | 4-aminobutanoic acid | |
|---|---|---|
| CAS Number | 56-12-2 | |
| Molecular Formula |
C4H9NO2 |
|
| Molecular Weight (MW) | 103.12 | |
| SMILES | C(CC(=O)O)CN | |
| InChIKey | BTCSSZJGUNDROE-UHFFFAOYSA-N |
4-Aminobutyric acid (GABA) is a major endogenous inhibitory neurotransmitter in the central nervous system that targets ionotropic GABAA and metabotropic GABAB receptors. Binding of GABA opens ligand-gated chloride channels or activates G-protein-coupled signaling pathways, resulting in neuronal hyperpolarization and inhibition of neurotransmission. Downstream effects include the suppression of synaptic excitability, regulation of neuronal circuit dynamics, and modulation of motor control, anxiety, and sleep. [1][2]
|
Concentration
Volume
Mass
|
|---|
| Solvent | Solubility & Note |
|---|---|
| Water | 21 mg/mL |
| DMSO |
Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.) |
| Ethanol | Insoluble |
| Water | 20 mg/mL |
| DMSO |
Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.) |
| Ethanol | Insoluble |
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
- 4-Aminobutyric acid (GABA) Clinical Trials
- 4-Aminobutyric acid (GABA) Solubility in DMSO
- 4-Aminobutyric acid (GABA) Stock Solution
- 4-Aminobutyric acid (GABA) Storage
- 4-Aminobutyric acid (GABA) Stability
- 4-Aminobutyric acid (GABA) Molecular Weight
- 4-Aminobutyric acid (GABA) SMILES
- 4-Aminobutyric acid (GABA) Chemical Structure (2D and 3D)
- 4-Aminobutyric acid (GABA) SDS｜MSDS