GsMTx4: Selectivity & Specificity
GsMTx4 is a potent inhibitor of PIEZO1 (Kd near 200 nM), JNK, c-Jun, AKT, CAPN2, FN1, COL1A1, TRPC6, ACTA2, MMP3, MMP13, PPP3CA, NFATC1. GsMTx4 exhibits the greatest inhibitory potency toward PIEZO1 (IC50 = 200 nM).
GsMTx4 is a potent inhibitor of PIEZO1 (Kd near 200 nM), JNK, c-Jun, AKT, CAPN2, FN1, COL1A1, TRPC6, ACTA2, MMP3, MMP13, PPP3CA, NFATC1. GsMTx4 exhibits the greatest inhibitory potency toward PIEZO1 (IC50 = 200 nM).