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Eloralintide

Cat.No.P1262

Eloralintide (LY-3841136) is a selective amylin receptor agonist with EC50 of 23.9 pM for human AMY1R and 253.8 pM for human AMY3R, and it reduces appetite, food intake, body weight, and fat mass with weak conditioned taste avoidance and favorable gastrointestinal tolerability.

Amino-acid Sequence

CAS No. 2883634-40-8

Quality Control

Featured Inhibitors	Y-27632 Dihydrochloride SB431542 CHIR-99021 (Laduviglusib) RMC-7977 RMC-6236 (Daraxonrasib) MRTX1133 MG132 Z-VAD-FMK VT3989 IAG933

Chemical Information & Solubility

Storage (From the date of receipt)	3 years-20°Cpowder	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
			1 month-20°Cin solvent

In vivo
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Biological Activity

Description	Eloralintide (LY-3841136) is a selective amylin receptor agonist with EC50 of 23.9 pM for human AMY1R and 253.8 pM for human AMY3R, and it reduces appetite, food intake, body weight, and fat mass with weak conditioned taste avoidance and favorable gastrointestinal tolerability.

References
https://pubmed.ncbi.nlm.nih.gov/41109426/

References

https://pubmed.ncbi.nlm.nih.gov/41109426/

Product Information

Molecular Formula	C₂₀₁H₃₁₉N₄₉O₆₅S₂
Molecular Weight	4526.10
CAS No.	2883634-40-8
Shipping	Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)