research use only

Allo-aca (ARV-1803)

Cat.No.P1253

Allo-aca (ARV-1803) is a synthetic peptide that functions as a specific antagonist of the leptin receptor, effectively blocking leptin signaling in both in vitro and in vivo. It also demonstrates potential therapeutic applications in the treatment of ophthalmic diseases.

CAS No.

Quality Control

94.96

Featured Inhibitors	Y-27632 Dihydrochloride SB431542 CHIR-99021 (Laduviglusib) RMC-7977 RMC-6236 (Daraxonrasib) MRTX1133 MG132 Z-VAD-FMK VT3989 IAG933

Chemical Information & Solubility

Storage (From the date of receipt)	3 years-20°Cpowder	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
			1 month-20°Cin solvent

In vitro
Batch:

Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.

In vivo Formulation Calculator

Biological Activity

Description	Allo-aca (ARV-1803) is a synthetic peptide that functions as a specific antagonist of the leptin receptor, effectively blocking leptin signaling in both in vitro and in vivo. It also demonstrates potential therapeutic applications in the treatment of ophthalmic diseases.

References
https://pubmed.ncbi.nlm.nih.gov/24366600/ https://pubmed.ncbi.nlm.nih.gov/21353530/

References

https://pubmed.ncbi.nlm.nih.gov/24366600/
https://pubmed.ncbi.nlm.nih.gov/21353530/

Product Information

Molecular Formula	C₄₈H₇₅N₁₃O₁₅
Molecular Weight	1074.19
Shipping	Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)