New Akt Inhibitors

HomeNew Akt Inhibitors
Catalog No. Product Name Information
E5971 ZINC00640089 ZINC00640089 is a selective Lipocalin-2 (LCN2) inhibitor that suppresses cell proliferation, decreases cell viability, and reduces AKT phosphorylation levels in SUM149 cells. This compound shows promising research potential for inflammatory breast cancer (IBC) studies.
E4992 Afuresertib hydrochloride Afuresertib hydrochloride (GSK 2110183 hydrochloride, LAE002 hydrochloride) is an orally bioavailable, selective, ATP-competitive and potent inhibitor of pan-Akt kinase with Ki values of 0.08 nM, 2 nM, 2.6 nM for Akt1/Akt2/Akt3 respectively.
E5820 AKT Kinase Inhibitor AKT Kinase Inhibitor is an inhibitor of Akt that reverses the protective effects of Tadalafil (TAD) in LPS-induced RWPE-1 cells by decreasing cell viability, promoting apoptosis, and increasing pro-inflammatory cytokine levels.
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