Enzyme Substrate

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PROTAC Others Antineoplastic and Immunosuppressive Antibiotics Selection Antibiotics for Transfected Cell Antibiotics for Mammalian Cell Culture Antibiotics for Plant Cell Culture ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC Hydrotropic Agents

Cat.No.	Product Name	Information	Product Use Citations	Product Validations
S7777	Coelenterazine	Coelenterazine is a luminescent enzyme substrate for apoaequorin and Renilla luciferase. Renilla luciferase and substrate coelenterazine have been used as bioluminescence donors in bioluminescence resonance energy transfer (BRET) to detect protein-protein interactions. Coelenterazine is a superoxide anion-sensitive chemiluminescent probe, and it can also be used in the chemiluminescent detection of peroxynitrite.	BMC Biology, 2025, 23:51 BMC Biol, 2025, 23(1):51 Biochem Biophys Res Commun, 2025, 777:152215
S6580	D-Luciferin Potassium Salt	D-luciferin is the natural substrate of the enzyme luciferase (Luc) which catalyzes the production of the typical yellow-green light of fireflies. The 560 nm chemiluminescence from this reaction peaks within seconds, with light output that is proportional to luciferase concentration when the substrate luciferin is present in excess. The luciferase (luc) gene is a popular reporter gene for research and agent screening. Chemiluminescent techniques are virtually background-free, making the luc reporter gene ideal for detecting low-level gene expression. In addition to its role as a reporter of gene expression, luciferase is commonly used in an extremely sensitive assay for ATP.	Future Med Chem, 2023, 15(4):333-344 Org Biomol Chem, 2022, 20(9):1869-1873 Breast Cancer Res, 2021, 23(1):11

Cat.No.

Product Name

Information

Product Use Citations

Product Validations

S7777

Coelenterazine

Coelenterazine is a luminescent enzyme substrate for apoaequorin and Renilla luciferase. Renilla luciferase and substrate coelenterazine have been used as bioluminescence donors in bioluminescence resonance energy transfer (BRET) to detect protein-protein interactions. Coelenterazine is a superoxide anion-sensitive chemiluminescent probe, and it can also be used in the chemiluminescent detection of peroxynitrite.

BMC Biology, 2025, 23:51

BMC Biol, 2025, 23(1):51

Biochem Biophys Res Commun, 2025, 777:152215

S6580

D-Luciferin Potassium Salt

D-luciferin is the natural substrate of the enzyme luciferase (Luc) which catalyzes the production of the typical yellow-green light of fireflies. The 560 nm chemiluminescence from this reaction peaks within seconds, with light output that is proportional to luciferase concentration when the substrate luciferin is present in excess. The luciferase (luc) gene is a popular reporter gene for research and agent screening. Chemiluminescent techniques are virtually background-free, making the luc reporter gene ideal for detecting low-level gene expression. In addition to its role as a reporter of gene expression, luciferase is commonly used in an extremely sensitive assay for ATP.

Future Med Chem, 2023, 15(4):333-344

Org Biomol Chem, 2022, 20(9):1869-1873

Breast Cancer Res, 2021, 23(1):11