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SB 242084

Cat.No.E7488

SB 242084 is a selective, competitive and high-affinity (pKi=9.0) 5-HT2C receptor antagonist (crosses the blood-brain barrier). This compound increases basal activity of dopaminergic neurons in the ventral tegmental area (VTA) of the midbrain and dopamine release in the vomeronasal nucleus. It also increases mitochondrial gene expression and oxidative metabolism via 5-HT2A receptor. This chemical has good research potential in the negative symptoms of anxiety, depression and schizophrenia, as well as in acute organ damage.
SB 242084 Chemical Structure

Chemical Structure

Molecular Weight: 394.85

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Chemical Information, Storage & Stability

Molecular Weight 394.85 Formula Storage (From the date of receipt)
CAS No. 181632-25-7 -- Storage of Stock Solutions Solutions are unstable. Prepare fresh or purchase small, pre-packaged sizes. Repackage upon receipt.

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