Dantrolene sodium hemiheptahydrate
Catalog No.S4648 Synonyms: Dantrolene sodium salt, Dantrium, Sodium dantrolene
Molecular Weight(MW): 399.29
Dantrolene sodium hemiheptahydrate ia a skeletal muscle relaxant that acts by interfering with excitation-contraction coupling in the muscle fiber.
Purity & Quality Control
Choose Selective Calcium Channel Inhibitors
Biological Activity
| Description | Dantrolene sodium hemiheptahydrate ia a skeletal muscle relaxant that acts by interfering with excitation-contraction coupling in the muscle fiber. |
|---|---|
| In vitro |
Dantrolene sodium is a skeletal muscle relaxant, which inhibits intracellular Ca2+ release from the sarcoplasmic reticulum. Dantrolene sodium shows strong antioxidant activity in the linoleic acid emulsion system[2]. |
| In vivo | Dantrolene sodium (5 mg/kg) has a greater depressant action on the twitch contraction of the fast extensor digitorum longus (EDL) muscle than on the slow soleus (SOL) muscle[1]. |
Protocol
| Animal Research:[1] |
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Solubility (25°C)
| In vitro | DMSO | 14 mg/mL (35.06 mM) |
|---|---|---|
| Water | Insoluble | |
| Ethanol | Insoluble |
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Chemical Information
| Molecular Weight | 399.29 |
|---|---|
| Formula | C14H9N4O5.7/2H2O.Na |
| CAS No. | 24868-20-0 |
| Storage | powder |
| Synonyms | Dantrolene sodium salt, Dantrium, Sodium dantrolene |
Bio Calculators
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