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Salinomycin (Procoxacin) Chemical Structure
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Biological Activity
Salinomycin (Procoxacin) is an antibacterial and coccidiostat ionophore therapeutic agent. Salinomycin (Procoxacin) has been shown by Piyush Gupta to kill breast cancer stem cells at least 100 times more effectively than another popular anti-cancer compound (paclitaxel) in mice. The mechanism of action by which salinomycin (Procoxacin) kills cancer stem cells specifically remains unknown, but is thought to be due to its action as a potassium ionophore due to the detection of Nigericin in the same compound screen. Salinomycin has high toxicity and a narrow therapeutic window which may limit its clinical use. [1]
Chemical Information
| Molecular Weight (WM): | 751.00 |
|---|---|
| Formula: | C42H70O11 |
| CAS No.: | 53003-10-4 |
| Synonyms: |
Procoxacin
|
| Dissolve in (25°C): | DMSO <1mg/mL |
| Water <1mg/mL | |
| Ethanol <1mg/mL | |
| Storage: | 2 years-20°CPowder |
| 1 week-4°Cin DMSO | |
| 1 month-80°in DMSO |
Quality Control & MSDS
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