Salinomycin (Procoxacin)

Aminoglutethimide (Cytadren) is an anti-steroid drug which inhibits aromatase.

Catalog No.S2352
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Salinomycin (Procoxacin) Chemical Structure

Salinomycin (Procoxacin) Chemical Structure
Molecular Weight: 751.00

Product Information

Product Description

Biological Activity

Salinomycin (Procoxacin) is an antibacterial and coccidiostat ionophore therapeutic agent. Salinomycin (Procoxacin) has been shown by Piyush Gupta to kill breast cancer stem cells at least 100 times more effectively than another popular anti-cancer compound (paclitaxel) in mice. The mechanism of action by which salinomycin (Procoxacin) kills cancer stem cells specifically remains unknown, but is thought to be due to its action as a potassium ionophore due to the detection of Nigericin in the same compound screen. Salinomycin has high toxicity and a narrow therapeutic window which may limit its clinical use. [1]

Chemical Information

Molecular Weight (MW) 751.00
Formula

C42H70O11

CAS No. 53003-10-4
Synonyms Procoxacin
Solubility (25°C)
  • DMSO mg/mL
  • Water mg/mL
  • Ethanol mg/mL
Storage 2 years -20°CPowder
2 weeks4°Cin DMSO
6 months-80°Cin DMSO
Chemical Name

Research Area

Tech Support & FAQs

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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