HomeNew Glucagon Receptor Inhibitors

New Glucagon Receptor Inhibitors

Catalog No. Product Name Information
P1247 Exendin-4 Exendin-4 (Exenatide) is a 39-amino acid peptide and a long-acting potent agonist of glucagon-like peptide-1(GLP-1) receptor with an IC50 of 3.22 nM. It is used in research and as a potential long-term treatment for type 2 diabetes mellitus.
E4779 DMB DMB (GLP-1R agonist 2, Compound 2) is an agonist of the GLP-1 receptor (GLP-1R) with a Ki of 13.25 µM. It activates GLP-1R by forming hydrogen bonds with the Tyr42, Cys71, and Ser84 residues. DMB attenuates transient focal cerebral ischemia injury and inhibits neuronal apoptosis induced by MCAO.
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