New FGFR Inhibitors

Catalog No.	Product Name	Information
E6510	LOXO-435	Vepugratinib (LOXO‑435; LY3866288) is a potent, highly isoform‑selective small‑molecule inhibitor of FGFR3 that is engineered to retain activity against FGFR3 gatekeeper mutations. It also eexhibits potential antitumor activity in FGFR3‑altered advanced solid tumors, especially metastatic urothelial cancer.
E6659	TYRA-200	TYRA-200 is an orally bioavailable inhibitor of FGFR1/2/3 that exhibits potential to address clinically observed acquired resistance alterations in FGFR2, such as molecular brake and gatekeeper mutations.
F0647	Phospho-FGF Receptor (Tyr653/654) Antibody [F13P7]	FGFR1 (phospho Y653),Phospho-FGF Receptor (Tyr653/654),Phospho-FGF Receptor 1 (Tyr653/654)
E4727	TYRA-300	TYRA-300 , a 3-pyridylindazole analog, is a reversible and selective inhibitor of FGFR3 with an IC50 of 11 nM in Ba/F3 cells. It also exhibit potent activity in human bladder cancer cell lines harboring FGFR3 activating fusions or mutations.
≡ All FGFR Inhibitors