ULK Agonist

Featured Inhibitors
Inhibitors (10)
Chemical (1)
Agonist (1)
Activator (1)

Cat.No.	Product Name	Information	Product Use Citations	Product Validations
S8597	LYN-1604	LYN-1604 is a potential ULK1 agonist with IC50 of 1.66 μM against MDA-MB-231 cells and it binds to wild-type ULK1 with a binding affinity in the nanomole range (Kd=291.4 nM). The ULK1 (Y89A) mutant protein caused a sharp decrease in binding affinity with lower response and Kd than wild-type ULK1, ULK1 (K50A) and ULK1 (L53A) mutants.	Journal of Mens Health, 2025, 37-44 The Journal of Immunology, 2024, 1063-1068 Sci China Life Sci, 2022, 10.1007/s11427-022-2185-9

Cat.No.

Product Name

Information

Product Use Citations

Product Validations

S8597

LYN-1604

LYN-1604 is a potential ULK1 agonist with IC50 of 1.66 μM against MDA-MB-231 cells and it binds to wild-type ULK1 with a binding affinity in the nanomole range (Kd=291.4 nM). The ULK1 (Y89A) mutant protein caused a sharp decrease in binding affinity with lower response and Kd than wild-type ULK1, ULK1 (K50A) and ULK1 (L53A) mutants.

Journal of Mens Health, 2025, 37-44

The Journal of Immunology, 2024, 1063-1068

Sci China Life Sci, 2022, 10.1007/s11427-022-2185-9