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N-ras Inhibitors

Catalog No. Product Name Information Selective / Pan IC50 / Ki
S2797 Lonafarnib (SCH66336) Lonafarnib (SCH66336) is an orally bioavailable FPTase inhibitor for H-ras, K-ras-4B and N-ras with IC50 of 1.9 nM, 5.2 nM and 2.8 nM in cell-free assays, respectively. Phase 3. Pan N-ras, IC50: 2.8 nM