AMPK-related protein kinase Selective Inhibitors

Catalog No.	Product Name	Information	Selective / Pan	IC50 / Ki
S0177	XMD-17-51	XMD-17-51 (XMD17-51) is a potent and highly selective inhibitor of NUAK1.	Selective
S8161	ON123300	ON123300 is a potent and multi-targeted kinase inhibitor with IC50 of 3.9 nM, 5 nM, 26 nM, 26 nM, 9.2 nM and 11nM for CDK4, Ark5/NUAK1, PDGFRβ, FGFR1, RET (c-RET), and Fyn, respectively.	Selective	ARK5, IC50: 4.95 nM
S7317	WZ4003	WZ4003 is a highly specific NUAK kinase inhibitor with IC50 of 20 nM and 100 nM for NUAK1 and NUAK2 in cell-base assays, respectively, without significant inhibition on 139 other kinases.	Selective	NUAK1, IC50: 20 nM; NUAK2, IC50: 100 nM
S7318	HTH-01-015	HTH-01-015 is a potent and selective NUAK1 inhibitor with IC50 of 100 nM, >100-fold selectivity over NUAK2.	Selective	NUAK1, IC50: 100 nM