Y-27632 Dihydrochloride is a potent, selective ATP-competitive ROCK inhibitor. It blocks Rho/ROCK signaling by binding to the kinase catalytic domain, effectively relaxing phenylephrine pre-contracted corpus cavernosum smooth muscle.
Y-27632 Dihydrochloride IC50 for Cell-based and Cell-free Assays
Comprehensive lC50 Values for Y-27632 Dihydrochloride Across Cell-free Enzyme Inhibitory Profiles and Cell- based Functional Assays.