XAV-939 is a specific tankyrase inhibitor. It affects the Wnt/β-catenin signaling pathway by stabilizing Axin and promoting β-catenin degradation, effectively inhibiting tumor cell proliferation, migration, and chemoresistance, while modulating stem cell differentiation.
XAV-939 IC50 for Cell-based and Cell-free Assays
Comprehensive IC50 Values for XAV-939 Across Cell-free Enzyme Inhibitory Profiles and Cell-based Functional Assays.