CAS No. 55778-02-4
Batch:
Purity:99.07
Chemical Structure
Check the
WZ811
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | N-[[4-[(pyridin-2-ylamino)methyl]phenyl]methyl]pyridin-2-amine | |
|---|---|---|
| CAS Number | 55778-02-4 | |
| Molecular Formula |
C18H18N4
|
|
| Molecular Weight (MW) | 290.36 | |
| SMILES | C1=CC=NC(=C1)NCC2=CC=C(C=C2)CNC3=CC=CC=N3 | |
| InChIKey | KBVFRXIGQQRMEF-UHFFFAOYSA-N |
WZ811 is a potent, competitive CXCR4 antagonist. By blocking the binding of CXCL12 to the CXCR4 receptor, it effectively disrupts the CXCL12/CXCR4 signaling axis and suppresses downstream AKT and ERK/MAPK pathway activation. Consequently, WZ811 attenuates CXCL12-directed cellular chemotaxis, tumor cell migration, invasion, and survival, leading to reduced proliferation in CXCR4-expressing cancer cells.
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Concentration
Volume
Mass
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|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
30 mg/mL
(103.32 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
Note: Technical data last updated: Sep 1, 2026.