CAS No. 2229025-70-9
Batch:
Purity:98.30
Chemical Structure
Check the
WM-3835
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | 2-fluoro-N'-(3-hydroxyphenyl)sulfonyl-3-methyl-5-phenylbenzohydrazide | |
|---|---|---|
| CAS Number | 2229025-70-9 | |
| Molecular Formula |
C20H17FN2O4S |
|
| Molecular Weight (MW) | 400.42 | |
| SMILES | CC1=CC(=CC(=C1F)C(=O)NN[S](=O)(=O)C2=CC(=CC=C2)O)C3=CC=CC=C3 | |
| InChIKey | KVJFJJXCBRSCDY-UHFFFAOYSA-N |
WM-3835 is a small-molecule inhibitor targeting lysine acetyltransferase 7 (KAT7, also known as HBO1 or MYST2). By inhibiting KAT7 acetyltransferase activity, WM-3835 suppresses osteosarcoma cell proliferation and migration while inducing apoptosis. Pharmacological targeting of KAT7 impairs histone acetylation and disrupts gene expression programs essential for cancer cell survival and stem cell maintenance. [1]
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Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
80 mg/mL
(199.79 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 80 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.