Vorasidenib (AG-881): Mechanism of Action

Vorasidenib (AG-881) MOA:Targeting Mutant IDH/2-HG Pathway for Low-Grade Glioma

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Vorasidenib is a potent mutant IDH1/2 inhibitor. It affects IDH signaling by binding the enzyme, inhibiting 2-HG production.

Primary Applications and Mechanism of Action