Vorasidenib is a potent mutant IDH1/2 inhibitor. It affects IDH signaling by binding the enzyme, inhibiting 2-HG production.
Vorasidenib (AG-881) IC50 for Cell-based and Cell-free Assays
Comprehensive IC50 Values for Vorasidenib (AG-881) Across Cell-free Enzyme Inhibitory Profiles and Cell-based Functional Assays.